CN221465376U - Universal disposable ion test card - Google Patents
Universal disposable ion test card Download PDFInfo
- Publication number
- CN221465376U CN221465376U CN202323275774.9U CN202323275774U CN221465376U CN 221465376 U CN221465376 U CN 221465376U CN 202323275774 U CN202323275774 U CN 202323275774U CN 221465376 U CN221465376 U CN 221465376U
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- CN
- China
- Prior art keywords
- test card
- ion
- groove
- detection channel
- waste liquid
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- 238000012360 testing method Methods 0.000 title claims abstract description 42
- 238000009413 insulation Methods 0.000 claims abstract description 17
- 238000001514 detection method Methods 0.000 claims description 36
- 239000007788 liquid Substances 0.000 claims description 20
- 239000002699 waste material Substances 0.000 claims description 19
- 239000000463 material Substances 0.000 claims description 14
- 230000026683 transduction Effects 0.000 claims description 11
- 238000010361 transduction Methods 0.000 claims description 11
- 238000002347 injection Methods 0.000 claims description 9
- 239000007924 injection Substances 0.000 claims description 9
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 7
- 239000004020 conductor Substances 0.000 claims description 6
- 239000012528 membrane Substances 0.000 claims description 6
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 5
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 5
- 229910021607 Silver chloride Inorganic materials 0.000 claims description 4
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 claims description 4
- 150000002500 ions Chemical class 0.000 abstract description 44
- 238000004519 manufacturing process Methods 0.000 abstract description 3
- 238000012423 maintenance Methods 0.000 abstract description 2
- 239000000243 solution Substances 0.000 description 19
- 238000004458 analytical method Methods 0.000 description 8
- 229910001415 sodium ion Inorganic materials 0.000 description 6
- FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 description 5
- 238000010586 diagram Methods 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 4
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 description 4
- NPYPAHLBTDXSSS-UHFFFAOYSA-N Potassium ion Chemical compound [K+] NPYPAHLBTDXSSS-UHFFFAOYSA-N 0.000 description 4
- 229910001424 calcium ion Inorganic materials 0.000 description 4
- 229910001425 magnesium ion Inorganic materials 0.000 description 4
- 229910001414 potassium ion Inorganic materials 0.000 description 4
- 239000000126 substance Substances 0.000 description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 229910002651 NO3 Inorganic materials 0.000 description 1
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 150000001450 anions Chemical class 0.000 description 1
- -1 biochemistry Substances 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 230000008094 contradictory effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000004880 explosion Methods 0.000 description 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 238000004451 qualitative analysis Methods 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
Landscapes
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Abstract
The utility model discloses a universal disposable ion test card, which comprises a card body, a support body and a hydrophilic film, wherein the card body is provided with a conductive line pattern layer and an insulation groove, when the card is used, an ion sensitive film and a reference film can be directly dripped into the card body, the card is convenient to manufacture, single ions can be detected according to design or multiple ions can be detected simultaneously, the card is disposable, maintenance is not needed, the card can be directly discarded after being used, and the economic value is high.
Description
Technical Field
The utility model relates to the technical field of electrochemical biological sensing, in particular to a universal disposable ion test card.
Background
The sensitive membrane electrode (Sensing Membrane Electrodes, SME), i.e. chemical and biological sensitive membrane electrode, refers to a class of electrodes that are selectively responsive to ionic or molecular species, i.e. ion selective electrodes recommended by the international association of pure and applied chemistry (IUPAC). The electrode is used as a conversion element and an immobilization carrier, the biosensing substance is used as a molecular recognition object to be immobilized on the surface of the electrode, then target molecules are captured on the surface of the electrode through the specific recognition function among molecules, and the basic electrode converts concentration signals into measurable electric signals such as electric potential, current, resistance or capacitance and the like to serve as response signals, so that quantitative or qualitative analysis of target analytes is realized.
The ion selective electrode is an indication electrode with selectivity to a certain specific ion, has wide application in the aspects of medicine, biochemistry, chemical industry, environmental protection, food and the like, and has important medical clinical significance in particular to the detection of particles in human body fluid.
The traditional ion electrode and the current general solid ion electrode are mostly reused, have extremely high requirements on the manufacturing process, high cost, complex detection process, slower response and continuous maintenance in the use process.
Disclosure of Invention
The utility model aims to overcome the defects of the prior art and provide a universal disposable ion test card which has high sensitivity, is simple and convenient to manufacture and convenient to use.
Based on the above purpose, the utility model provides a general disposable ion test card, which comprises a test card body, a support body and a hydrophilic film, wherein the test card body is provided with a conductive line pattern and an insulation groove; one end of the conducting wire pattern layer is exposed at the bottom of the insulation groove, and the other end of the conducting wire pattern layer is arranged at one end of the test card body as a connecting wire; the insulation groove is positioned right above one end point of the conductive line pattern layer, an ion sensitive film or a reference film can be accommodated in the insulation groove, and the lower surface of the ion sensitive film or the reference film is connected with the exposed end of the conductive line pattern layer.
Further, the conductive line pattern exposed in the insulation groove is formed by two types of materials: a conductive material and a transduction material; the conductive material comprises one or two of conductive silver paste or Ag/AgCl paste; the transduction material includes a mixed polyvinyl alcohol transduction material.
Further, the support body is provided with a communicated micro-channel hole, the micro-channel hole can be directly clung to the upper part of the test card body to form a detection channel groove and a waste liquid groove, and the insulation groove is positioned on the central axis of the detection channel groove.
Further, the hydrophilic membrane is provided with a sample injection port and a vent hole, and can be directly sealed and clung to the upper part of the support body to form a detection channel and a waste liquid pool together with the detection channel groove and the waste liquid groove; the sample injection port is positioned above one end, far away from the waste liquid pool, of the detection channel and is communicated with the detection channel; the vent hole is positioned above one end of the waste liquid pool far away from the detection channel and is communicated with the waste liquid pool.
Drawings
The achievement of the objects, functional features and advantages of the present utility model will be further described with reference to the accompanying drawings, in conjunction with the embodiments.
FIG. 1 is a schematic diagram of a general-purpose disposable ion test card according to an embodiment of the utility model.
FIG. 2 is a schematic diagram of an explosion structure of a universal disposable ion test card according to an embodiment of the present utility model.
FIG. 3 is a schematic diagram of a general-purpose disposable ion test card body according to an embodiment of the present utility model.
FIG. 4 is a schematic diagram of a micro-channel structure of a universal disposable ion test card according to an embodiment of the present utility model.
FIG. 5 is a graph showing the detection of sodium ion concentration using a novel exemplary universal disposable ion test card.
FIG. 6 is a diagram showing the detection of sodium ion, potassium ion concentration, calcium ion and magnesium ion using the universal disposable ion test card according to the present embodiment.
Detailed Description
The technical solutions in the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model. It will be apparent that the described embodiments are only some, but not all, embodiments of the utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
It should be noted that all directional indicators (such as up, down, left, right, front, and rear … …) in the embodiments of the present utility model are merely used to explain the relative positional relationship, movement, etc. between the components in a particular posture (as shown in the drawings), and if the particular posture is changed, the directional indicators are changed accordingly.
Furthermore, the description of "first," "second," etc. in this disclosure is for descriptive purposes only and is not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include at least one such feature. In addition, the technical solutions of the embodiments may be combined with each other, but it is necessary to base that the technical solutions can be realized by those skilled in the art, and when the technical solutions are contradictory or cannot be realized, the combination of the technical solutions should be considered to be absent and not within the scope of protection claimed in the present utility model.
It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the utility model.
With reference to fig. 1-6, for the above purposes, the present utility model provides a universal disposable ion test card 1, where the test card 1 is a universal test card that can be used to detect the concentration of common ions in a solution, such as cations: sodium, potassium, calcium, magnesium, etc., such as anions: chloride, iodide, nitrate, phosphate, and the like. The utility model does not limit the types and the number of ion detection items, and can independently detect single ion concentration or simultaneously detect a plurality of ion concentrations according to different designs of the test card. The test card 1 is a disposable test card, is maintenance-free, and can be directly discarded after the test is finished.
Specifically, the universal disposable test card 1 comprises a test card body 6, a support body 5 and a hydrophilic film 4, and is formed by direct sealing and close fitting, so that the assembly is convenient. The test card body 6 is provided with a conductive pattern layer, which can be directly screen-printed.
In one embodiment, one end 63 of the conductive pattern may be designed to the edge of the test card as a connection line to facilitate insertion of the analytical device into the analytical device connector and the other end 64 is exposed at the bottom of the insulating recesses 61, 62. When the electrode is manufactured, the ion electrode sensitive film layer can be directly dripped into any one of the insulation grooves such as the insulation groove 61, and the reference film is dripped into the other insulation groove such as the insulation groove 62, so that the lower surfaces of the sensitive film layer and the reference film are in direct contact with the upper surface of the conductive line pattern layer, and the electrochemical signals can be conveniently collected. The simultaneous detection of several ions is not limited here, and a plurality of insulating grooves are designed if a plurality is used.
The conductive line pattern 64 exposed at the bottom of the insulating recesses 61 and 62 is composed of two types of materials: a conductive material and a transduction material; the conductive material comprises one or two of conductive silver paste or Ag/AgCl paste; the transduction material comprises a mixed polyvinyl alcohol transduction material.
In one embodiment, the conductive pattern layer in the exposed insulating groove is screen printed with two layers, the lower layer is conductive silver paste, the upper layer is mixed polyvinyl alcohol transduction material, and the other layers are conductive silver paste. FIG. 5 is a graph showing the concentration of sodium ions detected in this example, with a slope of up to 57, and excellent performance.
In another embodiment, the conductive line pattern layer in the exposed insulation groove is screen printed with three layers, the lower layer is conductive silver paste, the middle layer is Ag/AgCl paste, the upper layer is mixed polyvinyl alcohol transduction material, and the other places are conductive silver paste. FIG. 6 is a graph showing the concentration of sodium ion, potassium ion, calcium ion and magnesium ion detected simultaneously in the embodiment, the test card enters two solutions before and after, and the concentration of sodium ion and magnesium ion in the two solutions is unchanged; the potassium ion and the calcium ion are multiplied by 10, and the potential of the sodium ion and the potential of the magnesium ion in two different solutions are unchanged, so that the potentials of the potassium ion and the calcium ion are respectively increased by 57mV and 28mV, and the performance is excellent.
The insulating groove 61 or 62 is located right above one end point of the conductive line pattern layer, and can internally accommodate an ion sensitive film or a reference film, and the lower surface of the ion sensitive film or the reference film is connected with the upper surface of the conductive line pattern layer exposed inside. When the ions are detected, the ions to be detected are in direct contact with the ion sensitive film layer, the ion sensitive film can specifically adsorb the ions to be detected, different potential values are generated, the ions are detected by the analysis equipment through the conducting wire pattern layer, and then the concentration of the ions to be detected is analyzed.
The support body 5 is provided with a communicating micro-channel hole 51, which can be directly attached to the upper side of the test card body 6 to form a detection channel groove 52 and a waste liquid groove 53. After assembly, the insulating grooves 61 and 62 are located on the middle axis of the detection channel 52.
The hydrophilic membrane layer 4 is provided with a sample injection port 3 and a vent hole 2, and can be directly sealed and clung to the upper part of the supporting body 5 to form a detection channel and a waste liquid pool. The sample injection port 3 is positioned above one end of the detection channel 52 far away from the waste liquid pool and is communicated with the detection channel; the vent hole 2 is positioned above one end of the waste liquid pool far away from the detection channel and is communicated with the waste liquid pool. The vent hole is communicated with the atmosphere, so that the detection channel is communicated with the atmosphere, and the liquid can flow more smoothly. During detection, the constant value solution firstly enters a detection channel, one-point calibration is carried out, namely the constant value solution contacts with an ion electrode and a reference electrode in the channel, and an analysis device acquires an electrochemical signal; then the solution to be measured enters from the sample injection port and flows into the detection channel, and meanwhile the original constant value solution is discharged into the waste liquid pool, and when the solution to be measured contacts with the ion electrode and the reference electrode, the analysis equipment collects electrochemical signals to carry out ion detection.
In one embodiment, a method of using a universal disposable ion test card includes: s1: detection preparation: confirming the type of the ion test card, namely the type of the ion sensitive film layer in the groove; s2: the test card interfaces with the analysis device: inserting the universal disposable test reagent card into a connector of an analytical device; s3: automatic calibration: injecting a constant value solution from a sample injection port, automatically entering a detection channel, acquiring an electrochemical signal by analysis equipment, and storing the electrochemical signal in the analysis equipment; s4: sample detection: injecting the solution to be tested from the sample injection port, enabling the solution to be tested to enter a detection channel, discharging the constant value solution into a waste liquid pool, and automatically acquiring an electrochemical signal of the solution to be tested by analysis equipment; s5: outputting a detection result: the analysis equipment processes and analyzes the collected electrochemical signals and calculates the concentration value of each detected ion.
The foregoing description is only of the preferred embodiments of the present utility model and is not intended to limit the scope of the utility model, and all equivalent structures or equivalent processes using the descriptions and drawings of the present utility model or directly or indirectly applied to other related technical fields are included in the scope of the utility model.
Claims (4)
1. The utility model provides a general disposable ion test card which is characterized in that the test card comprises a test card body, a support body and a hydrophilic film, wherein the test card body is provided with a conductive line pattern layer and an insulation groove; one end of the conducting wire pattern layer is exposed at the bottom of the insulation groove, and the other end of the conducting wire pattern layer is arranged at one end of the test card body as a connecting wire; the insulation groove is positioned right above one end point of the conductive wire pattern layer, an ion sensitive film or a reference film can be accommodated in the insulation groove, and the lower surface of the ion sensitive film or the reference film is connected with the exposed end of the conductive wire pattern layer.
2. The universal disposable ion test card of claim 1, wherein the conductive trace layer exposed in the insulating recess is comprised of two types of materials: a conductive material and a transduction material; the conductive material comprises one or two of conductive silver paste or Ag/AgCl paste; the transduction material includes a mixed polyvinyl alcohol transduction material.
3. The universal disposable ion test card of claim 1, wherein the support body is provided with a communicating micro-channel hole which can be directly clung to the upper part of the test card body to form a detection channel groove and a waste liquid groove, and the insulation groove is positioned on the central axis of the detection channel groove.
4. The universal disposable ion test card according to claim 3, wherein the hydrophilic membrane is provided with a sample injection port and a vent hole, and can be directly sealed and clung to the upper part of the support body to form a detection channel and a waste liquid pool together with the detection channel groove and the waste liquid groove; the sample injection port is positioned above one end, far away from the waste liquid pool, of the detection channel and is communicated with the detection channel; the vent hole is positioned above one end of the waste liquid pool far away from the detection channel and is communicated with the waste liquid pool.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202323275774.9U CN221465376U (en) | 2023-12-03 | 2023-12-03 | Universal disposable ion test card |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202323275774.9U CN221465376U (en) | 2023-12-03 | 2023-12-03 | Universal disposable ion test card |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN221465376U true CN221465376U (en) | 2024-08-02 |
Family
ID=92359668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202323275774.9U Active CN221465376U (en) | 2023-12-03 | 2023-12-03 | Universal disposable ion test card |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN221465376U (en) |
-
2023
- 2023-12-03 CN CN202323275774.9U patent/CN221465376U/en active Active
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| GR01 | Patent grant | ||
| GR01 | Patent grant |