CO6241096A2 - Aislados antimicrobianos y anti-inflamatorios de extracto de regaliz - Google Patents
Aislados antimicrobianos y anti-inflamatorios de extracto de regalizInfo
- Publication number
- CO6241096A2 CO6241096A2 CO09137860A CO09137860A CO6241096A2 CO 6241096 A2 CO6241096 A2 CO 6241096A2 CO 09137860 A CO09137860 A CO 09137860A CO 09137860 A CO09137860 A CO 09137860A CO 6241096 A2 CO6241096 A2 CO 6241096A2
- Authority
- CO
- Colombia
- Prior art keywords
- extract
- care
- clause
- composition
- oral care
- Prior art date
Links
- 230000003110 anti-inflammatory effect Effects 0.000 title abstract 3
- 230000000845 anti-microbial effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 5
- 230000000844 anti-bacterial effect Effects 0.000 abstract 2
- 230000000843 anti-fungal effect Effects 0.000 abstract 2
- 229940121375 antifungal agent Drugs 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000002324 mouth wash Substances 0.000 abstract 2
- 239000003826 tablet Substances 0.000 abstract 2
- 239000000606 toothpaste Substances 0.000 abstract 2
- 229940034610 toothpaste Drugs 0.000 abstract 2
- GDAAEAXMNLVRCZ-GOSISDBHSA-N 7-O-Methyllicoricidin Natural products O(C)c1c(C/C=C(\C)/C)c(OC)cc2OC[C@H](c3c(O)c(C/C=C(\C)/C)c(O)cc3)Cc12 GDAAEAXMNLVRCZ-GOSISDBHSA-N 0.000 abstract 1
- 235000010585 Ammi visnaga Nutrition 0.000 abstract 1
- 244000153158 Ammi visnaga Species 0.000 abstract 1
- 241000196324 Embryophyta Species 0.000 abstract 1
- 241000628997 Flos Species 0.000 abstract 1
- VTAJIXDZFCRWBR-UHFFFAOYSA-N Licoricesaponin B2 Natural products C1C(C2C(C3(CCC4(C)CCC(C)(CC4C3=CC2)C(O)=O)C)(C)CC2)(C)C2C(C)(C)CC1OC1OC(C(O)=O)C(O)C(O)C1OC1OC(C(O)=O)C(O)C(O)C1O VTAJIXDZFCRWBR-UHFFFAOYSA-N 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 229940112822 chewing gum Drugs 0.000 abstract 1
- 235000015218 chewing gum Nutrition 0.000 abstract 1
- 239000000551 dentifrice Substances 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 229930003935 flavonoid Natural products 0.000 abstract 1
- 150000002215 flavonoids Chemical class 0.000 abstract 1
- 235000017173 flavonoids Nutrition 0.000 abstract 1
- LPLVUJXQOOQHMX-UHFFFAOYSA-N glycyrrhetinic acid glycoside Natural products C1CC(C2C(C3(CCC4(C)CCC(C)(CC4C3=CC2=O)C(O)=O)C)(C)CC2)(C)C2C(C)(C)C1OC1OC(C(O)=O)C(O)C(O)C1OC1OC(C(O)=O)C(O)C(O)C1O LPLVUJXQOOQHMX-UHFFFAOYSA-N 0.000 abstract 1
- 229960004949 glycyrrhizic acid Drugs 0.000 abstract 1
- UYRUBYNTXSDKQT-UHFFFAOYSA-N glycyrrhizic acid Natural products CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(=O)O)OC6OC(C(O)C(O)C6OC7OC(O)C(O)C(O)C7C(=O)O)C(=O)O UYRUBYNTXSDKQT-UHFFFAOYSA-N 0.000 abstract 1
- 239000001685 glycyrrhizic acid Substances 0.000 abstract 1
- 235000019410 glycyrrhizin Nutrition 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- GDAAEAXMNLVRCZ-UHFFFAOYSA-N licorisoflavan A Natural products C1C=2C(OC)=C(CC=C(C)C)C(OC)=CC=2OCC1C1=CC=C(O)C(CC=C(C)C)=C1O GDAAEAXMNLVRCZ-UHFFFAOYSA-N 0.000 abstract 1
- GDAAEAXMNLVRCZ-SFHVURJKSA-N licorisoflavan A Chemical compound C1([C@@H]2COC=3C=C(C(=C(OC)C=3C2)CC=C(C)C)OC)=CC=C(O)C(CC=C(C)C)=C1O GDAAEAXMNLVRCZ-SFHVURJKSA-N 0.000 abstract 1
- GBRZTUJCDFSIHM-UHFFFAOYSA-N licorisoflavan B Natural products C1C=2C(OC)=C(CC=C(C)C)C(O)=CC=2OCC1C1=CC=C(O)C(CC=C(C)C)=C1O GBRZTUJCDFSIHM-UHFFFAOYSA-N 0.000 abstract 1
- 239000007937 lozenge Substances 0.000 abstract 1
- 229940051866 mouthwash Drugs 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Birds (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Dermatology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
La presente invención proporciona en un aspecto productos hechos de un extracto CO2 súper crítico no obvio y novedoso de las raíces de Glicirriza sp., efectivo como un antiinflamatorio, antibacterial, antifungal y agente antiadherente, incluyendo, pero no limitándose a los productos para el cuidado oral y para el cuidado del cuerpo. La presente invención proporciona en otro aspecto componentes aislados del extracto CO2 súper crítico de las raíces de Glicirriza sp., efectivo como un antiinflamatorio, un agente antibacterial, antifungal y antiadherente incluyendo, pero no limitándose a productos para el cuidado oral y para el cuidado del cuerpo. 1.- Una composición para el cuidado del cuerpo o para el cuidado oral que comprende un extracto de la raíz de la planta de glicirriza sp que comprende un extracto libre de ácido glicirrizico esencialmente en donde los componentes principales del extracto son flavonoides prenilatados y en donde la raíz extraída por un proceso de extracción CO2 es súper crítico. 2.- La composición para el cuidado del cuerpo o para el cuidado oral tal y como se reivindica en la cláusula 1, caracterizada porque dicho extracto es de Glicirriza uralensis y en donde los componentes principales del extracto son licoricidina y licorisoflavan A. 3.- La composición para el cuidado del cuerpo o para el cuidado oral tal y como se reivindica en la cláusula 1, caracterizada porque el extracto es de Glicirriza glabra y en donde el componente principal del extracto es glabidrina. 4.- La composición para el cuidado oral tal y como se reivindica en la cláusula 1, caracterizada porque la composición para el cuidado oral es seleccionada del grupo que consiste de un dentífrico, pasta de dientes, limpiador de dentaduras, hilo dental, palillos de dientes, enjuague bucal, lavados bucales, pastillas, goma de mascar, tabletas que pueden disolverse, tabletas que pueden ser masticadas y cápsulas. 5.- El dentífrico tal y como se reivindica en la cláusula 4, caracterizado porque dicho extracto está a una concentración de alrededor de 0.002 por ciento por peso a alrededor de 2.0 por ciento por peso. 6.- El limpiador para dentadura tal y como se reivindica en la cláusula 4, caracterizado porque dicho extracto está a una concentración de 0.002 por ciento por peso a alrededor de 2.0 por ciento por peso.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/799,524 US8236360B2 (en) | 2007-05-02 | 2007-05-02 | Supercritical CO2 liquorice extract and products made there from |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO6241096A2 true CO6241096A2 (es) | 2011-01-20 |
Family
ID=39939691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO09137860A CO6241096A2 (es) | 2007-05-02 | 2009-12-02 | Aislados antimicrobianos y anti-inflamatorios de extracto de regaliz |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8236360B2 (es) |
| EP (1) | EP2150233B1 (es) |
| JP (1) | JP5438672B2 (es) |
| CN (1) | CN101730521A (es) |
| AU (1) | AU2008248272B2 (es) |
| BR (1) | BRPI0810774A2 (es) |
| CA (1) | CA2685845C (es) |
| CO (1) | CO6241096A2 (es) |
| MX (1) | MX2009011869A (es) |
| RU (1) | RU2423116C1 (es) |
| SG (1) | SG180038A1 (es) |
| WO (1) | WO2008137009A1 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA013370B1 (ru) * | 2009-05-15 | 2010-04-30 | Общество С Ограниченной Ответственностью "Вдс" | Средство для профилактики стоматологических заболеваний |
| US8715625B1 (en) | 2010-05-10 | 2014-05-06 | The Clorox Company | Natural oral care compositions |
| JP5893324B2 (ja) * | 2011-09-30 | 2016-03-23 | サンスター株式会社 | メチルメルカプタン抑制剤 |
| WO2014037528A1 (en) * | 2012-09-07 | 2014-03-13 | Analyticon Discovery Gmbh | Composition comprising licoricidine |
| JP2015093848A (ja) * | 2013-11-12 | 2015-05-18 | 丸善製薬株式会社 | 皮膚化粧料及び頭髪化粧料 |
| CN105806964A (zh) * | 2014-12-30 | 2016-07-27 | 洛阳惠中兽药有限公司 | 刺五加甘草制剂的检测方法及其应用 |
| WO2017049328A1 (en) * | 2015-09-16 | 2017-03-23 | Tshwane University Of Technology | A chewable gum composition |
| RU2645070C2 (ru) * | 2016-06-06 | 2018-02-15 | Федеральное государственное бюджетное учреждение науки Институт клеточного и внутриклеточного симбиоза Уральского отделения Российской академии наук | Способ получения антимикробных пептидов из тромбоцитов курицы домашней |
| CN108101923B (zh) * | 2017-12-14 | 2020-07-31 | 中山大学 | 一种光甘草定单体的分离提纯方法 |
| EP3806686A4 (en) * | 2018-06-12 | 2022-03-23 | Buzzelet Development And Technologies Ltd | DENTAL CARE DEVICE AND THEIR USE |
| CN108743580B (zh) * | 2018-07-31 | 2019-03-19 | 南京道尔医药科技有限公司 | 甘草异黄烷甲在制备治疗抑郁症药物中的应用 |
| CN109223663A (zh) * | 2018-11-23 | 2019-01-18 | 丹东康齿灵牙膏有限公司 | 一种用于牙龈炎症的中草药牙膏及其制备方法 |
| BE1028259B1 (fr) * | 2020-05-04 | 2021-12-07 | Dyna S A R L | Composition de renforcement et/ou de régulation de la réponse immunitaire |
| CN113786399A (zh) * | 2021-10-13 | 2021-12-14 | 吉林大学 | 光甘草定在制备沙门氏菌ⅲ型分泌系统抑制剂中的应用 |
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| US20060269494A1 (en) | 2005-05-27 | 2006-11-30 | Gupta Shyam K | New Ubiquitin-Proteasome Regulating Compounds and Their Application in Cosmetic and Pharmaceutical Formulations |
| US7736629B2 (en) * | 2005-11-18 | 2010-06-15 | Colgate-Palmolive Company | Red herbal dentifrice |
| CN100404526C (zh) | 2006-01-20 | 2008-07-23 | 华中科技大学 | 一种提取分离甘草酸、甘草黄酮和甘草多糖的方法 |
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2007
- 2007-05-02 US US11/799,524 patent/US8236360B2/en active Active
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2008
- 2008-05-01 CA CA2685845A patent/CA2685845C/en not_active Expired - Fee Related
- 2008-05-01 BR BRPI0810774A patent/BRPI0810774A2/pt not_active Application Discontinuation
- 2008-05-01 RU RU2009144535/15A patent/RU2423116C1/ru not_active IP Right Cessation
- 2008-05-01 EP EP08767466.9A patent/EP2150233B1/en not_active Not-in-force
- 2008-05-01 CN CN200880023333A patent/CN101730521A/zh active Pending
- 2008-05-01 WO PCT/US2008/005578 patent/WO2008137009A1/en active Application Filing
- 2008-05-01 MX MX2009011869A patent/MX2009011869A/es active IP Right Grant
- 2008-05-01 JP JP2010506311A patent/JP5438672B2/ja not_active Expired - Fee Related
- 2008-05-01 AU AU2008248272A patent/AU2008248272B2/en not_active Ceased
- 2008-05-01 SG SG2010077592A patent/SG180038A1/en unknown
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- 2009-12-02 CO CO09137860A patent/CO6241096A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2685845A1 (en) | 2008-11-13 |
| EP2150233B1 (en) | 2018-07-11 |
| JP5438672B2 (ja) | 2014-03-12 |
| US8236360B2 (en) | 2012-08-07 |
| WO2008137009A1 (en) | 2008-11-13 |
| AU2008248272B2 (en) | 2012-03-08 |
| MX2009011869A (es) | 2010-02-24 |
| SG180038A1 (en) | 2012-05-30 |
| AU2008248272A1 (en) | 2008-11-13 |
| US20080274179A1 (en) | 2008-11-06 |
| RU2423116C1 (ru) | 2011-07-10 |
| JP2010526067A (ja) | 2010-07-29 |
| CA2685845C (en) | 2014-07-29 |
| EP2150233A1 (en) | 2010-02-10 |
| BRPI0810774A2 (pt) | 2015-09-15 |
| CN101730521A (zh) | 2010-06-09 |
| EP2150233A4 (en) | 2015-08-12 |
| RU2009144535A (ru) | 2011-06-10 |
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