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DE10108614B4 - Water-soluble concentrate of a metabolism-influencing active substance - Google Patents

Water-soluble concentrate of a metabolism-influencing active substance Download PDF

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Publication number
DE10108614B4
DE10108614B4 DE10108614A DE10108614A DE10108614B4 DE 10108614 B4 DE10108614 B4 DE 10108614B4 DE 10108614 A DE10108614 A DE 10108614A DE 10108614 A DE10108614 A DE 10108614A DE 10108614 B4 DE10108614 B4 DE 10108614B4
Authority
DE
Germany
Prior art keywords
metabolism
water
active substance
soluble concentrate
influencing active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE10108614A
Other languages
German (de)
Other versions
DE10108614A1 (en
Inventor
Dariush Behnam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aquanova AG
Original Assignee
Aquanova AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE10108614A priority Critical patent/DE10108614B4/en
Application filed by Aquanova AG filed Critical Aquanova AG
Priority to DE10164844A priority patent/DE10164844B4/en
Priority to PCT/EP2002/001416 priority patent/WO2002085328A2/en
Priority to AU2002250914A priority patent/AU2002250914A1/en
Priority to EP02719799A priority patent/EP1377273B1/en
Priority to AT02719799T priority patent/ATE425743T1/en
Priority to ES02719799T priority patent/ES2324400T3/en
Priority to CA002436273A priority patent/CA2436273A1/en
Priority to MXPA03007141A priority patent/MXPA03007141A/en
Priority to US10/470,749 priority patent/US20040081670A1/en
Priority to EP05027278A priority patent/EP1645267A3/en
Priority to JP2002582902A priority patent/JP2004531530A/en
Priority to EP04010510A priority patent/EP1475083B1/en
Priority to AT04010510T priority patent/ATE381923T1/en
Priority to DE50213362T priority patent/DE50213362D1/en
Priority to DE50211435T priority patent/DE50211435D1/en
Publication of DE10108614A1 publication Critical patent/DE10108614A1/en
Application granted granted Critical
Publication of DE10108614B4 publication Critical patent/DE10108614B4/en
Priority to HK05103936.6A priority patent/HK1073994B/en
Priority to JP2006115962A priority patent/JP2006241167A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A23L33/11—Plant sterols or derivatives thereof, e.g. phytosterols
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/18—Antioxidants, e.g. antiradicals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE10108614A 2001-02-11 2001-02-22 Water-soluble concentrate of a metabolism-influencing active substance Expired - Lifetime DE10108614B4 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
DE10164844A DE10164844B4 (en) 2001-02-22 2001-02-22 Tocopherol concentrate
DE10108614A DE10108614B4 (en) 2001-02-22 2001-02-22 Water-soluble concentrate of a metabolism-influencing active substance
AT04010510T ATE381923T1 (en) 2001-02-11 2002-02-11 METHOD FOR PRODUCING AN ACTIVE INGREDIENTS CONCENTRATE AND ACTIVE INGREDIENTS CONCENTRATE
EP02719799A EP1377273B1 (en) 2001-02-11 2002-02-11 Method for producing an isoflavone concentrate
AT02719799T ATE425743T1 (en) 2001-02-11 2002-02-11 METHOD FOR PRODUCING AN ISOFLAVONE CONCENTRATE
ES02719799T ES2324400T3 (en) 2001-02-11 2002-02-11 PROCEDURE FOR THE PRODUCTION OF A CONCENTRATE OF ISOFLAVONAS.
CA002436273A CA2436273A1 (en) 2001-02-11 2002-02-11 Method for producing an active ingredient concentrate, and an active ingredient concentrate
MXPA03007141A MXPA03007141A (en) 2001-02-11 2002-02-11 Method for producing an active ingredient concentrate, and an active ingredient concentrate.
US10/470,749 US20040081670A1 (en) 2001-02-11 2002-02-11 Method for producing an active ingredient concentrate, and an active ingredient concentrate
EP05027278A EP1645267A3 (en) 2001-02-11 2002-02-11 Method for producing an active ingredient concentrate and active ingredient concentrate
PCT/EP2002/001416 WO2002085328A2 (en) 2001-02-11 2002-02-11 Method for producing an active ingredient concentrate, and an active ingredient concentrate
EP04010510A EP1475083B1 (en) 2001-02-11 2002-02-11 Method for producing an active ingredient concentrate, and active ingredient concentrate
AU2002250914A AU2002250914A1 (en) 2001-02-11 2002-02-11 Method for producing an active ingredient concentrate, and an active ingredient concentrate
DE50213362T DE50213362D1 (en) 2001-02-11 2002-02-11 METHOD FOR PRODUCING AN ISOFLAVONE CONCENTRATE
DE50211435T DE50211435D1 (en) 2001-02-11 2002-02-11 Process for the preparation of a drug concentrate and drug concentrate
JP2002582902A JP2004531530A (en) 2001-02-11 2002-02-11 Preparation of active substance concentrates and active substance concentrates
HK05103936.6A HK1073994B (en) 2001-02-11 2005-05-10 Method for producing an active ingredient concentrate, and active ingredient concentrate
JP2006115962A JP2006241167A (en) 2001-02-11 2006-04-19 Method for producing active ingredient concentrate and active ingredient concentrate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10108614A DE10108614B4 (en) 2001-02-22 2001-02-22 Water-soluble concentrate of a metabolism-influencing active substance

Publications (2)

Publication Number Publication Date
DE10108614A1 DE10108614A1 (en) 2002-09-05
DE10108614B4 true DE10108614B4 (en) 2005-04-28

Family

ID=7675168

Family Applications (2)

Application Number Title Priority Date Filing Date
DE10108614A Expired - Lifetime DE10108614B4 (en) 2001-02-11 2001-02-22 Water-soluble concentrate of a metabolism-influencing active substance
DE10164844A Expired - Lifetime DE10164844B4 (en) 2001-02-22 2001-02-22 Tocopherol concentrate

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE10164844A Expired - Lifetime DE10164844B4 (en) 2001-02-22 2001-02-22 Tocopherol concentrate

Country Status (1)

Country Link
DE (2) DE10108614B4 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012103767A1 (en) * 2012-04-27 2013-10-31 Chemische Fabrik Budenheim Kg Use of solubilizate comprising antimicrobial agent, emulsifier and water, as antimicrobial agent which is enclosed in micelles, e.g. for bacteriostatic or germ-reducible treatment of room air, food, objects by applying to object surfaces
US8778922B2 (en) 2009-01-08 2014-07-15 Lipocine Inc. Steroidal compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US9498485B2 (en) 2014-08-28 2016-11-22 Lipocine Inc. Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030236236A1 (en) * 1999-06-30 2003-12-25 Feng-Jing Chen Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
DE10158447B4 (en) * 2001-11-30 2005-02-10 Aquanova German Solubilisate Technologies (Agt) Gmbh Ascorbic Solubilisate
DE10306177A1 (en) * 2003-02-13 2004-09-02 Aquanova German Solubilisate Technologies (Agt) Seaweed oil, essential oil, terpene, phosphatidylserine, omega-3 fatty acid, lanolin, selin or D-panthenol concentrate containing excess polysorbate useful as an additive for foods, cosmetics, pharmaceuticals
DE20319249U1 (en) * 2003-12-10 2004-12-30 Aquanova German Solubilisate Technologies (Agt) Gmbh Lutein Concentrate
DE502004009901D1 (en) * 2004-07-22 2009-09-24 Aquanova Ag SOLUBILISATES OF ESSENTIAL OILS AND OTHER SUBSTANCES
DE102005032352A1 (en) * 2005-07-08 2007-01-11 Aquanova German Solubilisate Technologies (Agt) Gmbh Solubilizer for an active ingredient concentrate in the food industry comprises a St. John's wort extract, a roseda extract or a tarragon extract, a polysorbate emulsifier and water
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
WO2016033549A2 (en) 2014-08-28 2016-03-03 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
WO2016205423A2 (en) 2015-06-15 2016-12-22 Lipocine Inc. Composition and method for oral delivery of androgen prodrugs
EP3544614A4 (en) 2016-11-28 2020-08-05 Lipocine Inc. ORAL TESTOSTERONE UNDECANOATE THERAPY
CA3107214A1 (en) 2018-07-20 2020-01-23 Lipocine Inc. Liver disease

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04300830A (en) * 1991-03-28 1992-10-23 Zeria Pharmaceut Co Ltd Preparation of aqueous solutions of vitamin E
WO1995024832A1 (en) * 1994-03-15 1995-09-21 Smithkline Beecham Plc Stable, optically clear compositions
US6180130B1 (en) * 1996-10-07 2001-01-30 Roche Vitamins Inc. Vitamin E preparations for beverage applications
DE10104847A1 (en) * 2000-06-09 2001-12-20 Aquanova Getraenketechnologie Water-soluble concentrates of alpha-tocopherol or its derivatives and polysorbate used in skin cosmetics, medicines, drinks or food supplements

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04300830A (en) * 1991-03-28 1992-10-23 Zeria Pharmaceut Co Ltd Preparation of aqueous solutions of vitamin E
WO1995024832A1 (en) * 1994-03-15 1995-09-21 Smithkline Beecham Plc Stable, optically clear compositions
US6180130B1 (en) * 1996-10-07 2001-01-30 Roche Vitamins Inc. Vitamin E preparations for beverage applications
DE10104847A1 (en) * 2000-06-09 2001-12-20 Aquanova Getraenketechnologie Water-soluble concentrates of alpha-tocopherol or its derivatives and polysorbate used in skin cosmetics, medicines, drinks or food supplements

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8778922B2 (en) 2009-01-08 2014-07-15 Lipocine Inc. Steroidal compositions
US8865695B2 (en) 2009-01-08 2014-10-21 Lipocine Inc. Steroidal compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
DE102012103767A1 (en) * 2012-04-27 2013-10-31 Chemische Fabrik Budenheim Kg Use of solubilizate comprising antimicrobial agent, emulsifier and water, as antimicrobial agent which is enclosed in micelles, e.g. for bacteriostatic or germ-reducible treatment of room air, food, objects by applying to object surfaces
US9498485B2 (en) 2014-08-28 2016-11-22 Lipocine Inc. Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters

Also Published As

Publication number Publication date
DE10164844B4 (en) 2005-05-25
DE10108614A1 (en) 2002-09-05

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