DE102015000112A1 - Automated system for patient-related storage and filling of drugs - Google Patents

Abstract

System for patient-bound storage and for automatic, patient-bound filling of solid, single dose oral medication, in particular tablets, capsules, pills or drops, from original medication blisters associated with particular patients (blister blisters, preferably original blister packs filled by the manufacturer) in at least one of the same patient associated container with in each case at least one tablet compartment for receiving the medication of the respective patient for a certain intake time. Systems are known which are based on the storage of loose drugs, which therefore previously deblistered, d. H. were removed from their blister to be loosely stored in bulk and fed to the system, where they are preferably welded into plastic bags. To increase drug safety, in the system of the present invention, the single mediman doses are removed in real time from the original blister and filled into the corresponding bulge of a patient blister. The detour via a collecting container and the mixing of different batch numbers are thereby avoided, the annoying Entblistern deleted.

Description

The invention relates to a system for patient-bound storage and for automatic, patient-bound filling of solid, single-dose oral medication doses, especially tablets, capsules, pills or drops, from each patient specific originated drug blisters (Quellblister, preferably those filled by the manufacturer Original blister packs) in at least one of the same patient associated container with at least one tablet compartment for receiving the medication of each patient for a certain period and / or time. Preferably, each patient container comprises tablet compartments for 4 times (morning, noon, evening, night) on 7 days of the week.

Systems are known which are mainly used in large pharmacies and blister centers and are based on the storage of loose drugs, which therefore previously deblistered, d. H. from their blister to be stored in larger numbers, ideally separated by batch numbers. Due to patient-specific information, these loosely stored individual drug doses are then filled manually or automatically into patient-bound containers. These containers can z. B. be real-time welded plastic bag or special patient blister.

A major disadvantage of these known methods is the mixing of the single drug doses of different original blisters, in the worst case (and more common than usual in current practice) even different batch numbers and / or manufacturing data or locations and blending in the patient blister different medicines in common subjects. Another problem is that in the known machines, all drugs run through the same handling systems, which accumulate drug dusts, which can ultimately lead to unwanted and sometimes dangerous contamination of subsequent medications. The effects of such drug interference on the patient's organism are both unpredictable and unpredictable and therefore unacceptable under today's safety aspects. Furthermore, it is difficult, if not practical, for the medical pharmacist, if at all practicable, to store the medication packages to be reimbursed by the social funds, which normally contain several blisters of a drug, sorted strictly according to patient assignment as soon as they have started but are not yet used up.

The object of the present invention is to overcome the described disadvantages of the known systems by means of an automated system for patient-bound storage and filling of medicaments according to claim 1. Advantageous embodiments of the invention are set forth in the dependent claims. The system according to the present invention ideally comprises a plurality of holders ( 1 ), in which the original blister ( 4a . 4b , ...) are kept by one patient and inserted into the automatic filling system if required. Ideally, such a holder ( 1 ) at least one original blister ( 4a . 4b , ...) of each drug needed for the patient's automatic medication, so that a change of the holder ( 1 ) is normally not required during the running process. These patient-bound mounts ( 1 ) are managed and stored manually and / or automatically. Within the automatic filling system either the original blister ( 4a . 4b , ...) moves in its holder to the patient container or vice versa or the transfer of each single dose of medication is carried out by an intermediate carrier ( 3c ) from the original blister ( 4a . 4b , ...) receives a single dose taken and then to the patient container ( 2 ) again. This intermediate carrier ( 3c ) must then be cleaned at regular intervals, ideally at least always between two different drugs, in order to avoid dust buildup and consequent interactions or impurities. The patient container ( 2 ) ideally has 7 times 4 filling areas (for 4 administration times on 7 weekdays), whereby each filling area of the patient container ( 2 ) on several separate subjects ( 2a ), so that the drugs can ideally be bottled according to type.

It should be mentioned that here with patient container ( 2 ), any kind of receptacle that can receive the medication (s) for a patient for one or more administration times. However, special disposable blisters are considered hygienic and economically advantageous here.

It should be noted that the terms "single drug dose" or "tablet" used in this specification mean any type of solid, single dose oral medication to be taken orally, ie in particular tablets, pills, capsules, drops, etc.

• 1 – 1a – 1b – Träger für die Ausgangsblister Ein Gestell oder Rahmen, auf dem die Ausgangsblister (4a, 4b, 4c, 4d, 4e, 4f, 4g, ...) bevorzugt Original-Ausdrückpackungen der pharmazeutischen Industrie) dauerhaft bis zum Aufbrauchen des jeweiligen Medikaments befestigt werden.
• 2 – Patientengebundener Aufbewahrungsbehälter (2), bevorzugt ein individualisierter Patientenblister mit 7 × 4 Teilblistern für 4 unterschiedliche Einnahmezeitpunkte an 7 Tagen. Jeder Teilblister umfasst mehrere Einzeldosis-Behälter (2a).
• 3 – Entnahme- und Abfüllvorrichtung, die mit beispielsweise mit einem Stößel (3a) die Medikamenten-Einzeldosis aus ihrem Originalbehälter (4a, 4b, ...) entnimmt, sie direkt in den Patientenbehälter (2) fallen lässt oder sie zunächst mittels eines Transportbehälters (3c) zum Patientenbehälter (2) bewegt und dort einfüllt.

The system consists essentially of the following components:

• 1 - 1a - 1b - Carrier for the original blisters A frame or frame on which the blister ( 4a . 4b . 4c . 4d . 4e . 4f . 4g , ...) preferred original expressing packages of the pharmaceutical industry) are permanently attached until the consumption of the respective drug.
• 2 - Patient-bound storage container ( 2 ), preferably an individualized patient blister with 7 × 4 partial blisters for 4 different administration times in 7 days. Each sub-blister comprises several single-dose containers ( 2a ).
• 3 - removal and filling device, which with for example with a plunger ( 3a ) the single dose of medication from its original container ( 4a . 4b , ...) takes them directly into the patient container ( 2 ) or first by means of a transport container ( 3c ) to the patient container ( 2 ) and filled there.

Claims (10)

Automated system for patient-bound storage and filling of solid, single dose oral medication, in particular tablets, pills, capsules, drops, etc., characterized in that the individual medication single doses either directly from the source blister ( 4a . 4b , ...) in the patient-bound storage container ( 2 ) or by means of one or more intermediate containers ( 3c ), which record the single dose of medication in real time for a short time and to the 2 ). Storage and filling system according to claim 1, characterized in that it comprises one or more patient-bound receiving device (s), which is / are each assigned to a specific patient, for receiving in each case one or more medicament blisters (source blisters) associated with the patient ( 4a . 4b , ...) and one or more receiving devices for receiving at least one container, the at least one compartment ( 2a ) for storing the medication of a patient for at least one time of administration. Storage and filling system according to claims 1 and / or 2, characterized in that the different single drug doses into separate compartments ( 2a ) should be bottled to avoid possible interactions between the different medicinal products and to facilitate any subsequent visual follow-up. Storage and filling system according to claims 1 and / or 3, characterized in that the patient-bound destination container ( 2 ) one or more subjects for each administration ( 2a ) for single drug doses for unmixed filling. Storage and filling system according to one of the preceding claims, characterized in that the intermediate container is cleaned at regular and / or irregular intervals by blowing off, suction, brushing or other suitable methods and freed from the traces of the preceding drugs to preclude dangerous interactions. Storage and filling system according to one of the preceding claims, characterized in that the individual medication doses by cutting and / or punching and / or ejection and / or suction and / or expressions and / or expelling and / or squeezing out of the source blister ( 4a . 4b , ...) are taken. Storage and filling system according to one of the preceding claims, characterized in that at least a part of the source blister ( 4a . 4b , ...) of each patient together in a patient-bound holding and storage device ( 1 ) and kept. Storage and filling system according to one of the preceding claims, characterized in that the patient-bound holding and storage devices ( 1 ) manually and / or automatically be stored and retrieved. Storage and filling system according to one of the preceding claims, characterized in that the patient-bound holding and storage devices ( 1 ) are automatically fed to the filling station. Storage and filling system according to one of the preceding claims, characterized in that the patient-bound target blister ( 2 ) is checked for proper filling by suitable sensors and / or an image processing system.

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