DE60036881D1 - Neues nichtstrukturelles hcv polypeptid - Google Patents
Neues nichtstrukturelles hcv polypeptidInfo
- Publication number
- DE60036881D1 DE60036881D1 DE60036881T DE60036881T DE60036881D1 DE 60036881 D1 DE60036881 D1 DE 60036881D1 DE 60036881 T DE60036881 T DE 60036881T DE 60036881 T DE60036881 T DE 60036881T DE 60036881 D1 DE60036881 D1 DE 60036881D1
- Authority
- DE
- Germany
- Prior art keywords
- polypeptides
- new non
- hcv polypeptide
- polynucleotides
- structural hcv
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/18—Togaviridae; Flaviviridae
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16750299P | 1999-11-24 | 1999-11-24 | |
| US167502P | 1999-11-24 | ||
| PCT/US2000/032326 WO2001038360A2 (en) | 1999-11-24 | 2000-11-22 | Novel hcv non-structural polypeptide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60036881D1 true DE60036881D1 (de) | 2007-12-06 |
| DE60036881T2 DE60036881T2 (de) | 2008-07-10 |
Family
ID=22607625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60036881T Expired - Lifetime DE60036881T2 (de) | 1999-11-24 | 2000-11-22 | Neues nichtstrukturelles hcv-polypeptid |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1233982B1 (de) |
| JP (1) | JP2003516732A (de) |
| KR (1) | KR100788812B1 (de) |
| CN (2) | CN101684146A (de) |
| AT (1) | ATE376558T1 (de) |
| AU (1) | AU2574601A (de) |
| CA (1) | CA2390082C (de) |
| DE (1) | DE60036881T2 (de) |
| WO (1) | WO2001038360A2 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7491808B2 (en) | 2000-06-15 | 2009-02-17 | Novartis Vaccines And Diagnostics, Inc. | HCV non-structural protein mutants and uses thereof |
| US6680059B2 (en) | 2000-08-29 | 2004-01-20 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
| US7022830B2 (en) | 2000-08-17 | 2006-04-04 | Tripep Ab | Hepatitis C virus codon optimized non-structural NS3/4A fusion gene |
| EP1947185B1 (de) | 2000-08-17 | 2011-07-20 | Tripep Ab | HCV NS3/4A kodierende Nukleinsäure |
| US6858590B2 (en) | 2000-08-17 | 2005-02-22 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
| EP2172552A3 (de) | 2001-10-11 | 2010-07-21 | Merck Sharp & Dohme Corp. | Rekombinante Nukleinsäuren beinhaltend Regionen von AD6 |
| WO2003031588A2 (en) | 2001-10-11 | 2003-04-17 | Merck & Co., Inc. | Hepatitis c virus vaccine |
| CN1678630A (zh) * | 2002-07-02 | 2005-10-05 | 希龙公司 | 具有修饰的ns3结构域的hcv融合蛋白 |
| US7927840B2 (en) | 2006-09-11 | 2011-04-19 | Gen Probe Incorporated | Method for detecting West Nile Virus nucleic acids in the 3′ non-coding region |
| ES2890882T3 (es) | 2002-10-16 | 2022-01-24 | Gen Probe Inc | Composiciones y procedimientos para detectar el virus del Nilo occidental |
| GB0226722D0 (en) * | 2002-11-15 | 2002-12-24 | Glaxo Group Ltd | Vaccine |
| CN1984677A (zh) * | 2004-05-17 | 2007-06-20 | 希龙公司 | 截短的丙肝病毒ns5结构域以及含有该截短结构域的融合蛋白 |
| EP1799868B1 (de) | 2004-08-27 | 2012-01-18 | Novartis Vaccines and Diagnostics, Inc. | Nichtstrukturelle hcv-proteinmutanten und verwendungsmöglichkeiten dafür |
| MX2007004662A (es) * | 2004-10-18 | 2007-11-23 | Globeimmune Inc | Terapia basada en levaduras para infeccion cronica por hepatitis c. |
| EP2570423B1 (de) | 2005-06-17 | 2023-05-03 | MSD Italia S.r.l. | Nukleinsäureimpfstoff für Hepatitis-C-Virus |
| CA2661492A1 (en) | 2006-08-25 | 2008-02-28 | Novartis Ag | Hcv fusion polypeptides |
| EP2185195A2 (de) | 2007-08-16 | 2010-05-19 | Tripep Ab | Immunogen-plattform |
| US8728489B2 (en) | 2008-09-19 | 2014-05-20 | Globeimmune, Inc. | Immunotherapy for chronic hepatitis C virus infection |
| ES2497016T3 (es) * | 2009-03-30 | 2014-09-22 | bioMérieux | Soporte sólido de detección del VHC |
| CN102645534B (zh) * | 2012-04-26 | 2015-08-12 | 杭州市萧山区第一人民医院 | 基于量子点编码微球芯片检测丙型肝炎病毒的方法 |
| EP2968526A4 (de) | 2013-03-14 | 2016-11-09 | Abbott Lab | Hcv-antigen-antikörper-kombinationstest sowie verfahren und zusammensetzungen zur verwendung darin |
| MX2015012824A (es) * | 2013-03-14 | 2016-06-24 | Abbott Lab | Antigenos recombinantes ns3 del vhc y mutantes de los mismos para la deteccion mejorada de anticuerpos. |
| US9371374B2 (en) | 2013-03-14 | 2016-06-21 | Abbott Laboratories | HCV core lipid binding domain monoclonal antibodies |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5683864A (en) * | 1987-11-18 | 1997-11-04 | Chiron Corporation | Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies |
| WO1991015771A1 (en) * | 1990-04-04 | 1991-10-17 | Chiron Corporation | Combinations of hepatitis c virus (hcv) antigens for use in immunoassays for anti-hcv antibodies |
| EP0573624A4 (en) * | 1991-11-07 | 1997-09-17 | Baxter Diagnostics Inc | Epitope mapping ot the c33c region of hcv |
| US5709995A (en) * | 1994-03-17 | 1998-01-20 | The Scripps Research Institute | Hepatitis C virus-derived peptides capable of inducing cytotoxic T lymphocyte responses |
| DE4428705A1 (de) * | 1994-08-12 | 1996-02-15 | Boehringer Mannheim Gmbh | Rekombinantes Antigen aus der NS3-Region des Hepatitis C Virus |
| US6143715A (en) * | 1997-08-11 | 2000-11-07 | Boehringer Ingelheim (Canada) Ltd. | Hepatitis C inhibitor peptide analogues |
| US6211338B1 (en) * | 1997-11-28 | 2001-04-03 | Schering Corporation | Single-chain recombinant complexes of hepatitis C virus NS3 protease and NS4A cofactor peptide |
| AU746258B2 (en) * | 1998-01-30 | 2002-04-18 | General Hospital Corporation, The | Genetic immunization with nonstructural proteins of hepatitis C virus |
| JP4782927B2 (ja) * | 1999-05-04 | 2011-09-28 | ベーリンガー インゲルハイム (カナダ) リミテッド | 代理細胞ベースシステム及びc型肝炎ウイルスns3プロテアーゼの活性を評価する方法 |
-
2000
- 2000-11-22 EP EP00989206A patent/EP1233982B1/de not_active Expired - Lifetime
- 2000-11-22 AU AU25746/01A patent/AU2574601A/en not_active Abandoned
- 2000-11-22 CA CA2390082A patent/CA2390082C/en not_active Expired - Fee Related
- 2000-11-22 KR KR1020027006693A patent/KR100788812B1/ko not_active Expired - Fee Related
- 2000-11-22 WO PCT/US2000/032326 patent/WO2001038360A2/en active Search and Examination
- 2000-11-22 CN CN200910170570A patent/CN101684146A/zh active Pending
- 2000-11-22 JP JP2001540123A patent/JP2003516732A/ja active Pending
- 2000-11-22 DE DE60036881T patent/DE60036881T2/de not_active Expired - Lifetime
- 2000-11-22 CN CN00818577A patent/CN1425027A/zh active Pending
- 2000-11-22 AT AT00989206T patent/ATE376558T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001038360A9 (en) | 2002-12-12 |
| CN101684146A (zh) | 2010-03-31 |
| WO2001038360A2 (en) | 2001-05-31 |
| JP2003516732A (ja) | 2003-05-20 |
| CA2390082A1 (en) | 2001-05-31 |
| AU2574601A (en) | 2001-06-04 |
| KR100788812B1 (ko) | 2007-12-27 |
| EP1233982A2 (de) | 2002-08-28 |
| CA2390082C (en) | 2010-06-29 |
| EP1233982B1 (de) | 2007-10-24 |
| WO2001038360A3 (en) | 2002-03-07 |
| DE60036881T2 (de) | 2008-07-10 |
| CN1425027A (zh) | 2003-06-18 |
| ATE376558T1 (de) | 2007-11-15 |
| KR20020065537A (ko) | 2002-08-13 |
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| KR950000881A (ko) | 새로운 한국형 씨(C)형 간염 바이러스 씨디엔에이(cDNA) 절편의 뉴클레오티드 서열 및 이로부터 유추된 아미노산 서열 | |
| WO2004089978A3 (en) | Use of hcv proteins |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8381 | Inventor (new situation) |
Inventor name: COIT, DORIS, EMERYVILLE, CALIF., US Inventor name: MEDINA-SELBY, ANGELICA, EMERYVILLE, CALIF., US Inventor name: SELBY, MARK, EMERYVILLE, CALIF., US Inventor name: HOUGHTON, MICHAEL, EMERYVILLE, CALIF., US |
|
| 8339 | Ceased/non-payment of the annual fee | ||
| 8370 | Indication related to discontinuation of the patent is to be deleted | ||
| 8363 | Opposition against the patent |