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DE602004015980D1 - Verfahren zur insulinproduktion in pflanzen - Google Patents

Verfahren zur insulinproduktion in pflanzen

Info

Publication number
DE602004015980D1
DE602004015980D1 DE602004015980T DE602004015980T DE602004015980D1 DE 602004015980 D1 DE602004015980 D1 DE 602004015980D1 DE 602004015980 T DE602004015980 T DE 602004015980T DE 602004015980 T DE602004015980 T DE 602004015980T DE 602004015980 D1 DE602004015980 D1 DE 602004015980D1
Authority
DE
Germany
Prior art keywords
plants
insulin production
insulin
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004015980T
Other languages
English (en)
Inventor
Maurice M Moloney
Joseph Boothe
Richard Keon
Cory Nykiforuk
Rooijen Gijs Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SemBioSys Genetics Inc
Original Assignee
SemBioSys Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SemBioSys Genetics Inc filed Critical SemBioSys Genetics Inc
Publication of DE602004015980D1 publication Critical patent/DE602004015980D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H1/00—Processes for modifying genotypes ; Plants characterised by associated natural traits
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Developmental Biology & Embryology (AREA)
  • Environmental Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE602004015980T 2003-06-17 2004-06-17 Verfahren zur insulinproduktion in pflanzen Expired - Lifetime DE602004015980D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47881803P 2003-06-17 2003-06-17
US54953904P 2004-03-04 2004-03-04
PCT/CA2004/000896 WO2004111244A2 (en) 2003-06-17 2004-06-17 Methods for the production of insulin in plants

Publications (1)

Publication Number Publication Date
DE602004015980D1 true DE602004015980D1 (de) 2008-10-02

Family

ID=33555509

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004015980T Expired - Lifetime DE602004015980D1 (de) 2003-06-17 2004-06-17 Verfahren zur insulinproduktion in pflanzen

Country Status (23)

Country Link
US (2) US7547821B2 (de)
EP (2) EP1959017A1 (de)
JP (2) JP4864701B2 (de)
KR (1) KR101216762B1 (de)
CN (1) CN1836047B (de)
AR (1) AR044803A1 (de)
AT (1) ATE405660T1 (de)
AU (1) AU2004247762B2 (de)
BR (1) BRPI0411479A (de)
CA (1) CA2528741A1 (de)
CY (1) CY1108477T1 (de)
DE (1) DE602004015980D1 (de)
DK (1) DK1633876T3 (de)
EA (1) EA014887B1 (de)
ES (1) ES2313018T3 (de)
IL (1) IL172469A (de)
MX (1) MXPA05013723A (de)
NO (1) NO20055885L (de)
NZ (1) NZ544522A (de)
PL (1) PL1633876T3 (de)
PT (1) PT1633876E (de)
TW (1) TWI345587B (de)
WO (1) WO2004111244A2 (de)

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EP2074140B8 (de) 2006-10-04 2015-10-28 Case Western Reserve University Fibrillationsresistentes insulin und insulinanaloga
CN101688213A (zh) 2007-04-27 2010-03-31 陶氏环球技术公司 用于快速筛选微生物宿主以鉴定某些在表达异源蛋白质方面具有改善的产量和/或质量的菌株的方法
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
EP2910571B1 (de) * 2008-03-18 2016-10-05 Novo Nordisk A/S Proteasestabilisierte, acylierte insulinanaloga
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US20110195896A1 (en) * 2008-04-22 2011-08-11 Case Western Reserve University Isoform-specific insulin analogues
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US9200053B2 (en) 2008-07-31 2015-12-01 Case Western Reserve University Insulin analogues containing penta-fluoro-Phenylalanine at position B24
KR20120129875A (ko) * 2008-07-31 2012-11-28 케이스 웨스턴 리저브 유니버시티 염소화 아미노산을 갖는 인슐린 유사체
CN101736029B (zh) * 2008-11-21 2013-01-02 复旦大学 一种利用植物油体蛋白表达系统生产人胰岛素样生长因子-i的方法
US8399407B2 (en) * 2009-09-17 2013-03-19 Case Western Reserve University Non-standard insulin analogues
BR112012014025A2 (pt) 2009-12-11 2017-01-31 Univ Case Western Reserve análogo de insulina, ácido nucleico, vetor de expressão, célula hospedeira e método de tratar um paciente
CN102268451B (zh) * 2010-06-01 2014-03-12 安胜军 一种含有人胰岛素基因的表达载体及其构建方法与应用
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WO2013059213A1 (en) * 2011-10-18 2013-04-25 Amidebio, Llc Chemically and thermodynamically stable insulin analogues and improved methods for their production
US9352456B2 (en) 2011-10-26 2016-05-31 Black & Decker Inc. Power tool with force sensing electronic clutch
EP2836508B1 (de) 2012-04-11 2016-06-29 Novo Nordisk A/S Insulinformulierungen
EP2986315A4 (de) 2013-04-17 2017-03-01 AmideBio LLC Chemisch und thermodynamisch stabile insulinanaloga und verbesserte verfahren zu deren herstellung
KR101625746B1 (ko) 2013-09-23 2016-05-31 순천대학교 산학협력단 프로미니인슐린 재조합 단백질이 발현된 형질전환 식물 및 이의 제조방법
KR102569743B1 (ko) 2014-10-06 2023-08-23 케이스 웨스턴 리저브 유니버시티 이상 단일 사슬 인슐린 유사체
US20220096607A1 (en) * 2015-04-09 2022-03-31 Kinetiq Therapeutics, Llc Subcutaneous therapeutic enzyme formulations, uses, and methods for generating thereof
CN115154591B (zh) 2016-12-16 2023-04-14 诺和诺德股份有限公司 含胰岛素的药物组合物
KR102642178B1 (ko) * 2017-08-08 2024-02-29 중앙대학교 산학협력단 돌연변이에 의해, 혈중 반감기 및 공수병 바이러스 중화 효능이 증대된 공수병 바이러스 중화 항체
AU2019218315A1 (en) * 2018-02-09 2020-07-09 Jiangsu Hengrui Medicine Co., Ltd. Codon optimized precursor gene and signal peptide gene of human insulin analogue
CN114144426A (zh) * 2019-04-19 2022-03-04 印地安纳大学理事会 餐时或基础胰岛素类似物通过内部二硒桥的稳定化
EP4069278B1 (de) * 2019-12-06 2025-06-11 Dr. Mary Morris & Associates, LLC Verfahren und zusammensetzungen zur prävention von typ-1-diabetes
JP2023542241A (ja) * 2020-07-03 2023-10-05 クリヤ セラピューティクス， インコーポレイテッド 糖尿病を処置するための修飾型インスリンおよびグルコキナーゼ核酸
EP4190905A1 (de) 2021-12-01 2023-06-07 Core Biogenesis Verfahren zur reinigung von rekombinanten proteinen unter verwendung von ölkörperproteinen

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Also Published As

Publication number Publication date
HK1088037A1 (en) 2006-10-27
DK1633876T3 (da) 2008-12-08
WO2004111244A2 (en) 2004-12-23
TWI345587B (en) 2011-07-21
AR044803A1 (es) 2005-10-05
PL1633876T3 (pl) 2009-01-30
CA2528741A1 (en) 2004-12-23
BRPI0411479A (pt) 2006-07-25
PT1633876E (pt) 2008-11-03
JP2011200251A (ja) 2011-10-13
EP1633876B1 (de) 2008-08-20
AU2004247762B2 (en) 2010-05-27
JP2007523611A (ja) 2007-08-23
US20050039235A1 (en) 2005-02-17
ATE405660T1 (de) 2008-09-15
US20090282583A1 (en) 2009-11-12
JP4864701B2 (ja) 2012-02-01
AU2004247762A1 (en) 2004-12-23
NZ544522A (en) 2008-03-28
EA200600050A1 (ru) 2006-06-30
KR101216762B1 (ko) 2013-01-02
EP1633876A2 (de) 2006-03-15
ES2313018T3 (es) 2009-03-01
EA014887B1 (ru) 2011-02-28
IL172469A0 (en) 2006-04-10
CN1836047B (zh) 2010-12-22
NO20055885L (no) 2006-01-17
IL172469A (en) 2011-08-31
TW200510529A (en) 2005-03-16
MXPA05013723A (es) 2006-03-13
WO2004111244A3 (en) 2005-02-03
KR20060052705A (ko) 2006-05-19
US7547821B2 (en) 2009-06-16
CN1836047A (zh) 2006-09-20
EP1959017A1 (de) 2008-08-20
CY1108477T1 (el) 2014-04-09

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