DE602004017714D1 - ANTIBIOTISCHE TETRAHYDRO-b-CARBOLINDERIVATIVE - Google Patents
ANTIBIOTISCHE TETRAHYDRO-b-CARBOLINDERIVATIVEInfo
- Publication number
- DE602004017714D1 DE602004017714D1 DE602004017714T DE602004017714T DE602004017714D1 DE 602004017714 D1 DE602004017714 D1 DE 602004017714D1 DE 602004017714 T DE602004017714 T DE 602004017714T DE 602004017714 T DE602004017714 T DE 602004017714T DE 602004017714 D1 DE602004017714 D1 DE 602004017714D1
- Authority
- DE
- Germany
- Prior art keywords
- tetrahydro
- ppat
- structural formula
- carboline derivative
- bacteria
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- CFTOTSJVQRFXOF-UHFFFAOYSA-N 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole Chemical class N1C2=CC=CC=C2C2=C1CNCC2 CFTOTSJVQRFXOF-UHFFFAOYSA-N 0.000 title abstract 2
- 230000003115 biocidal effect Effects 0.000 title 1
- 241000894006 Bacteria Species 0.000 abstract 2
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 241000590002 Helicobacter pylori Species 0.000 abstract 1
- 102000004357 Transferases Human genes 0.000 abstract 1
- 108090000992 Transferases Proteins 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 230000006806 disease prevention Effects 0.000 abstract 1
- 229940037467 helicobacter pylori Drugs 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
- -1 structural formula I Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Maintenance And Management Of Digital Transmission (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46653703P | 2003-04-29 | 2003-04-29 | |
| PCT/US2004/013322 WO2004096802A2 (en) | 2003-04-29 | 2004-04-29 | ANTIBIOTIC TETRAHYDRO-β-CARBOLINE DERIVATIVES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602004017714D1 true DE602004017714D1 (de) | 2008-12-24 |
Family
ID=33418394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004017714T Expired - Fee Related DE602004017714D1 (de) | 2003-04-29 | 2004-04-29 | ANTIBIOTISCHE TETRAHYDRO-b-CARBOLINDERIVATIVE |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20060273819A1 (de) |
| EP (1) | EP1628977B1 (de) |
| JP (1) | JP2006525347A (de) |
| AT (1) | ATE414082T1 (de) |
| AU (1) | AU2004234405A1 (de) |
| CA (1) | CA2524125A1 (de) |
| DE (1) | DE602004017714D1 (de) |
| WO (1) | WO2004096802A2 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8571070B2 (en) | 2005-12-02 | 2013-10-29 | Broadcom Corporation | Method and system for speed negotiation for twisted pair links in fibre channel sytems |
| US8124616B2 (en) | 2007-11-30 | 2012-02-28 | Biota Scientific Management Pty Ltd | Bicyclic PPAT inhibitors as antibacterial agents |
| AU2008350293A1 (en) * | 2007-11-30 | 2009-08-20 | Biota Scientific Management Pty Ltd | Antibiotic tetrahydro-beta-carboline derivatives |
| WO2010008367A1 (en) | 2008-07-15 | 2010-01-21 | Lsi Corporation | System for injecting protocol specific errors during the certification of components in a storage area network |
| US9319348B2 (en) * | 2011-05-24 | 2016-04-19 | Cisco Technology, Inc. | Octal serial gigabit media-independent interface |
| AU2013243898A1 (en) | 2012-04-05 | 2014-10-23 | Chdi Foundation, Inc. | Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof |
| US9413497B2 (en) * | 2013-03-07 | 2016-08-09 | Viavi Solutions Deutschland Gmbh | Bit error pattern analyzer and method |
| JP2016536350A (ja) | 2013-09-26 | 2016-11-24 | シーエイチディーアイ ファウンデーション，インコーポレーテッド | キヌレニン−３−モノオキシゲナーゼ阻害薬、医薬組成物、及びこれらの使用方法 |
| JP6449893B2 (ja) | 2013-09-26 | 2019-01-09 | シーエイチディーアイ ファウンデーション，インコーポレーテッド | キヌレニン−３−モノオキシゲナーゼ阻害薬、医薬組成物、及びこれらの使用方法 |
| US9531625B2 (en) | 2015-01-28 | 2016-12-27 | Ciena Corporation | System and method for providing redundant network connections |
| CN119462646A (zh) * | 2024-11-07 | 2025-02-18 | 江苏科技大学 | 一种取代的四氢-β-咔啉衍生物、其合成方法及其用途 |
| CN119528904B (zh) * | 2025-01-21 | 2025-04-25 | 成都湃来生物科技有限公司 | 具有抗菌活性的吲哚衍生物、其制备方法、其用途及其制成的药物组合物和医疗器械 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1055203A (en) * | 1964-09-16 | 1967-01-18 | Ici Ltd | -ß-carboline derivatives, a process for their manufacture, and compositions containing them |
| US4283536A (en) * | 1977-12-29 | 1981-08-11 | University Of Vermont | Preparation of vincadifformine and related derivatives |
| FR2619111B1 (fr) * | 1987-08-07 | 1991-01-11 | Synthelabo | Derives de (piperidinyl-4)methyl-2 tetrahydro-1,2,3,4 9h-pyrido (3,4-b) indole, leur preparation et leur application en therapeutique |
| AR024158A1 (es) * | 1999-06-01 | 2002-09-04 | Smithkline Beecham Corp | Compuestos antibacterianos |
| FR2796644B1 (fr) * | 1999-07-23 | 2001-09-07 | Adir | Nouveaux derives de beta-carboline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| EP1286994A1 (de) * | 2000-05-15 | 2003-03-05 | Darwin Discovery Limited | Hydroxamsäure- und carbonsäure-derivate mit mmp und tnf hemmender wirkung |
| US6720330B2 (en) * | 2000-11-17 | 2004-04-13 | Pfizer Inc. | Somatostatin antagonists and agonists that act at the SST subtype 2 receptor |
| JP2004532816A (ja) * | 2000-12-08 | 2004-10-28 | スミスクライン・ビーチャム・コーポレイション | 抗菌性化合物 |
| ATE346067T1 (de) * | 2001-02-12 | 2006-12-15 | Lilly Icos Llc | Carbolinderivate |
| ES2248412T3 (es) * | 2001-02-12 | 2006-03-16 | Lilly Icos Llc | Derivados de carbolina. |
| WO2003035653A1 (fr) * | 2001-10-26 | 2003-05-01 | Nippon Soda Co.,Ltd. | Compose pyridothienopyrimidine et son sel |
| TWI329111B (en) * | 2002-05-24 | 2010-08-21 | X Ceptor Therapeutics Inc | Azepinoindole and pyridoindole derivatives as pharmaceutical agents |
-
2004
- 2004-04-29 JP JP2006513457A patent/JP2006525347A/ja active Pending
- 2004-04-29 AU AU2004234405A patent/AU2004234405A1/en not_active Abandoned
- 2004-04-29 WO PCT/US2004/013322 patent/WO2004096802A2/en active Application Filing
- 2004-04-29 US US10/554,756 patent/US20060273819A1/en not_active Abandoned
- 2004-04-29 DE DE602004017714T patent/DE602004017714D1/de not_active Expired - Fee Related
- 2004-04-29 CA CA002524125A patent/CA2524125A1/en not_active Abandoned
- 2004-04-29 EP EP04750953A patent/EP1628977B1/de not_active Expired - Lifetime
- 2004-04-29 AT AT04750953T patent/ATE414082T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1628977B1 (de) | 2008-11-12 |
| JP2006525347A (ja) | 2006-11-09 |
| WO2004096802A3 (en) | 2005-05-12 |
| ATE414082T1 (de) | 2008-11-15 |
| WO2004096802A2 (en) | 2004-11-11 |
| EP1628977A2 (de) | 2006-03-01 |
| CA2524125A1 (en) | 2004-11-11 |
| US20060273819A1 (en) | 2006-12-07 |
| AU2004234405A1 (en) | 2004-11-11 |
| WO2004096802A9 (en) | 2005-01-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |