[go: up one dir, main page]

DE69532416D1 - Methode und vorrichtung zur tröpfchenerzeugung mit hoher rate bei der durchfluss-cytometrie - Google Patents

Methode und vorrichtung zur tröpfchenerzeugung mit hoher rate bei der durchfluss-cytometrie

Info

Publication number
DE69532416D1
DE69532416D1 DE69532416T DE69532416T DE69532416D1 DE 69532416 D1 DE69532416 D1 DE 69532416D1 DE 69532416 T DE69532416 T DE 69532416T DE 69532416 T DE69532416 T DE 69532416T DE 69532416 D1 DE69532416 D1 DE 69532416D1
Authority
DE
Germany
Prior art keywords
flow cytometry
high rate
rate drop
drop production
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69532416T
Other languages
English (en)
Other versions
DE69532416T2 (de
Inventor
Den Engh Ger Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Washington
Original Assignee
University of Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Washington filed Critical University of Washington
Application granted granted Critical
Publication of DE69532416D1 publication Critical patent/DE69532416D1/de
Publication of DE69532416T2 publication Critical patent/DE69532416T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G01N15/1409—Handling samples, e.g. injecting samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G01N2015/1406—Control of droplet point
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/117497—Automated chemical analysis with a continuously flowing sample or carrier stream
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/117497—Automated chemical analysis with a continuously flowing sample or carrier stream
    • Y10T436/118339—Automated chemical analysis with a continuously flowing sample or carrier stream with formation of a segmented stream
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
DE69532416T 1994-10-14 1995-10-13 Methode und vorrichtung zur tröpfchenerzeugung mit hoher rate bei der durchfluss-cytometrie Expired - Lifetime DE69532416T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32327094A 1994-10-14 1994-10-14
US323270 1994-10-14
PCT/US1995/013308 WO1996012171A2 (en) 1994-10-14 1995-10-13 High speed flow cytometer droplet formation system

Publications (2)

Publication Number Publication Date
DE69532416D1 true DE69532416D1 (de) 2004-02-12
DE69532416T2 DE69532416T2 (de) 2004-12-02

Family

ID=23258439

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69532416T Expired - Lifetime DE69532416T2 (de) 1994-10-14 1995-10-13 Methode und vorrichtung zur tröpfchenerzeugung mit hoher rate bei der durchfluss-cytometrie

Country Status (6)

Country Link
US (1) US6133044A (de)
EP (1) EP0786078B1 (de)
JP (1) JPH10507524A (de)
AU (1) AU698929B2 (de)
DE (1) DE69532416T2 (de)
WO (1) WO1996012171A2 (de)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6861265B1 (en) 1994-10-14 2005-03-01 University Of Washington Flow cytometer droplet formation system
JP4323571B2 (ja) 1997-01-31 2009-09-02 エックスワイ， インコーポレイテッド 光学装置
US6149867A (en) * 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
GB2381004B (en) * 1997-12-31 2003-06-04 Xy Inc A method of sorting cells
US6071689A (en) * 1997-12-31 2000-06-06 Xy, Inc. System for improving yield of sexed embryos in mammals
RU2224992C2 (ru) * 1998-02-20 2004-02-27 Кси, Инк. Вибрационная система для проточного цитометра, предназначенного для сортинга
US6746873B1 (en) * 1998-02-20 2004-06-08 Xy, Inc. Vibratory system for a sorting flow cytometer
US6248590B1 (en) * 1998-02-27 2001-06-19 Cytomation, Inc. Method and apparatus for flow cytometry
WO2000006193A1 (en) 1998-07-30 2000-02-10 Xy, Inc. Equine system for non-surgical artificial insemination
US6372506B1 (en) * 1999-07-02 2002-04-16 Becton, Dickinson And Company Apparatus and method for verifying drop delay in a flow cytometer
EP1099484B1 (de) * 1999-11-11 2006-06-07 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin Vorrichtung und Verfahren zur Verabreichung von Tropfen
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
US6263745B1 (en) 1999-12-03 2001-07-24 Xy, Inc. Flow cytometer nozzle and flow cytometer sample handling methods
IL152714A (en) 2000-05-09 2014-03-31 Xy Llc High-purity spermatozoa populations carrying chromosome-x and chromosome-y
US20020086431A1 (en) * 2000-08-21 2002-07-04 Markham Walter Bruce Sample preparation and slide plating apparatus and method
CA2468772C (en) 2000-11-29 2013-10-29 George E. Seidel System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
US20020106308A1 (en) * 2001-02-02 2002-08-08 Zweifel Ronald A. Microdrop dispensing apparatus
US6669909B2 (en) * 2001-03-26 2003-12-30 Allegro Technologies Limited Liquid droplet dispensing
US7345758B2 (en) 2001-05-17 2008-03-18 Cytopeia Apparatus for analyzing and sorting biological particles
US20030211009A1 (en) * 2001-05-18 2003-11-13 Buchanan Kris S. Rapid multi-material sample input system
US6808683B2 (en) * 2001-09-25 2004-10-26 Cytonome, Inc. Droplet dispensing system
US6976590B2 (en) 2002-06-24 2005-12-20 Cytonome, Inc. Method and apparatus for sorting particles
US9943847B2 (en) 2002-04-17 2018-04-17 Cytonome/St, Llc Microfluidic system including a bubble valve for regulating fluid flow through a microchannel
US7362424B2 (en) * 2002-04-24 2008-04-22 The Institute For Systems Biology Compositions and methods for drop boundary detection and radiation beam alignment
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
WO2004012837A2 (en) 2002-08-01 2004-02-12 Xy, Inc. Low pressure sperm cell separation system
MXPA05001654A (es) 2002-08-15 2005-10-18 Xy Inc Citometro de flujo de alta resolucion.
JP3898103B2 (ja) * 2002-08-26 2007-03-28 独立行政法人科学技術振興機構 細胞分析分離装置
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
US7201875B2 (en) * 2002-09-27 2007-04-10 Becton Dickinson And Company Fixed mounted sorting cuvette with user replaceable nozzle
JP3891925B2 (ja) * 2002-12-03 2007-03-14 ベイバイオサイエンス株式会社 生物学的粒子の情報を得る装置
US7758811B2 (en) 2003-03-28 2010-07-20 Inguran, Llc System for analyzing particles using multiple flow cytometry units
ES2541121T3 (es) 2003-05-15 2015-07-16 Xy, Llc Clasificación eficiente de células haploides por sistemas de citometría de flujo
US20050147976A1 (en) * 2003-12-29 2005-07-07 Xing Su Methods for determining nucleotide sequence information
AU2005229073B2 (en) 2004-03-29 2010-08-19 Inguran, Llc Sperm suspensions for use in insemination
JP4304120B2 (ja) * 2004-04-30 2009-07-29 ベイバイオサイエンス株式会社 生物学的粒子をソーティングする装置及び方法
BRPI0513685A (pt) 2004-07-22 2008-05-13 Monsanto Technology Llc processo para enriquecimento de uma população de células de esperma
ES2264608B2 (es) * 2004-09-30 2007-08-16 Universidad De Sevilla Dispositivo y procedimiento para la atomizacion neumatica de liquidos mediante flujo implosivo de gas.
US7618770B2 (en) 2005-07-29 2009-11-17 Xy, Inc. Methods and apparatus for reducing protein content in sperm cell extenders
US20070116608A1 (en) * 2005-11-23 2007-05-24 Birdsell Michael P Vented ceramic tip arrangement for use with a microarray
US20070269348A1 (en) * 2006-05-19 2007-11-22 Cytopeia Incorporated Enhanced droplet flow cytometer system and method
ITTO20100651A1 (it) 2010-07-28 2012-01-29 Ist Sperimentale It Lazzaro Spallanza Procedimento ed apparecchiatura per la caratterizzazione e la separazione di spermatozoi con sensori micrometrici a leva sospesa
EP2864049A4 (de) * 2012-06-22 2016-01-20 Bio Rad Laboratories Düse mit kondensierter geometrie für durchflusszytometrie
US9222872B2 (en) 2012-09-19 2015-12-29 Inguran, Llc Flow cytometer nozzle tip
NZ706552A (en) 2012-09-19 2016-09-30 Inguran Llc Nozzle assembly for a flow cytometer system and methods of manufacture
US11668640B2 (en) 2015-03-06 2023-06-06 Inguran, Llc Nozzle assembly for a flow cytometry system and methods of manufacture
ES2900530T3 (es) 2013-04-12 2022-03-17 Becton Dickinson Co Configuración automatizada para la clasificación celular
WO2015111293A1 (ja) * 2014-01-24 2015-07-30 ソニー株式会社 粒子分取装置及び粒子分取方法
US11577366B2 (en) 2016-12-12 2023-02-14 Omax Corporation Recirculation of wet abrasive material in abrasive waterjet systems and related technology
USD868991S1 (en) 2017-03-28 2019-12-03 Becton, Dickinson And Company Register block
USD869676S1 (en) 2017-03-28 2019-12-10 Becton, Dickinson And Company Particle sorting module
US10443838B2 (en) * 2017-04-05 2019-10-15 Hall Labs Llc Method for forming consistently-sized and controllably-timed droplets
USD876668S1 (en) 2018-01-30 2020-02-25 Becton, Dickinson And Company Particle sorting module mount
USD872296S1 (en) 2018-01-30 2020-01-07 Becton, Dickinson And Company Particle sorting module
USD882817S1 (en) 2018-01-30 2020-04-28 Becton, Dickinson And Company Sample container
USD864415S1 (en) 2018-01-30 2019-10-22 Becton, Dickinson And Company Particle sorting system
JP7073805B2 (ja) * 2018-03-14 2022-05-24 株式会社リコー 液滴形成ヘッド、液滴形成装置、及び液滴形成方法
US20230236173A1 (en) 2020-06-22 2023-07-27 Westfaelische Wilhelms-Universitaet Muenster Sperm stratification
WO2022024575A1 (ja) * 2020-07-28 2022-02-03 ソニーグループ株式会社 微小粒子分析装置、微小粒子分取システム及び微小粒子分析方法
DE112021003987T5 (de) * 2020-07-28 2023-05-11 Sony Group Corporation Mikroteilchensortiervorrichtung und mikroteilchensortierverfahren

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3299354A (en) * 1962-07-05 1967-01-17 Coulter Electronics Aperture tube structure for particle study apparatus
US3810010A (en) * 1968-11-02 1974-05-07 Telefunken Patent Particle analysis method and apparatus wherein liquid containing particles is sucked into a constricted flow path
US3661460A (en) * 1970-08-28 1972-05-09 Technicon Instr Method and apparatus for optical analysis of the contents of a sheathed stream
US3826364A (en) * 1972-05-22 1974-07-30 Univ Leland Stanford Junior Particle sorting method and apparatus
US3761941A (en) * 1972-10-13 1973-09-25 Mead Corp Phase control for a drop generating and charging system
US4070617A (en) * 1974-05-08 1978-01-24 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Device for controlling the particle flow in an apparatus for measuring the properties of particles suspended in liquid
US3973196A (en) * 1974-05-24 1976-08-03 Coulter Electronics, Inc. Method and apparatus for ejecting a metered amount of particulate sample
US3963606A (en) * 1974-06-03 1976-06-15 Coulter Electronics, Inc. Semi-automatic adjusting delay for an electronic particle separator
US4014611A (en) * 1975-04-30 1977-03-29 Coulter Electronics, Inc. Aperture module for use in particle testing apparatus
US3960449A (en) * 1975-06-05 1976-06-01 The Board Of Trustees Of Leland Stanford Junior University Measurement of angular dependence of scattered light in a flowing stream
US4162282A (en) * 1976-04-22 1979-07-24 Coulter Electronics, Inc. Method for producing uniform particles
US4302166A (en) * 1976-04-22 1981-11-24 Coulter Electronics, Inc. Droplet forming apparatus for use in producing uniform particles
US4230558A (en) * 1978-10-02 1980-10-28 Coulter Electronics, Inc. Single drop separator
US4318481A (en) * 1979-08-20 1982-03-09 Ortho Diagnostics, Inc. Method for automatically setting the correct phase of the charge pulses in an electrostatic flow sorter
US4318482A (en) * 1979-08-20 1982-03-09 Ortho Diagnostics, Inc. Method for measuring the velocity of a perturbed jetting fluid in an electrostatic particle sorting system
US4318483A (en) * 1979-08-20 1982-03-09 Ortho Diagnostics, Inc. Automatic relative droplet charging time delay system for an electrostatic particle sorting system using a relatively moveable stream surface sensing system
US4317520A (en) * 1979-08-20 1982-03-02 Ortho Diagnostics, Inc. Servo system to control the spatial position of droplet formation of a fluid jet in a cell sorting apparatus
US4318480A (en) * 1979-08-20 1982-03-09 Ortho Diagnostics, Inc. Method and apparatus for positioning the point of droplet formation in the jetting fluid of an electrostatic sorting device
US4325483A (en) * 1979-08-20 1982-04-20 Ortho Diagnostics, Inc. Method for detecting and controlling flow rates of the droplet forming stream of an electrostatic particle sorting apparatus
US4691829A (en) * 1980-11-03 1987-09-08 Coulter Corporation Method of and apparatus for detecting change in the breakoff point in a droplet generation system
US4487320A (en) * 1980-11-03 1984-12-11 Coulter Corporation Method of and apparatus for detecting change in the breakoff point in a droplet generation system
US4395676A (en) * 1980-11-24 1983-07-26 Coulter Electronics, Inc. Focused aperture module
US4361400A (en) * 1980-11-26 1982-11-30 The United States Of America As Represented By The United States Department Of Energy Fluidic assembly for an ultra-high-speed chromosome flow sorter
US4673288A (en) * 1981-05-15 1987-06-16 Ratcom, Inc. Flow cytometry
US4818103A (en) * 1981-05-15 1989-04-04 Ratcom Flow cytometry
US4515274A (en) * 1981-12-02 1985-05-07 Coulter Corporation Particle analyzing and sorting apparatus
SU1056008A1 (ru) * 1982-01-25 1983-11-23 Предприятие П/Я Р-6681 Проточный цитофлуориметр
US4538733A (en) * 1983-10-14 1985-09-03 Becton, Dickinson And Company Particle sorter with neutralized collection wells and method of using same
US4631483A (en) * 1984-02-01 1986-12-23 Coulter Electronics, Inc. Particle analyzing apparatus and method of moving particles in suspension through such apparatus
US4660971A (en) * 1984-05-03 1987-04-28 Becton, Dickinson And Company Optical features of flow cytometry apparatus
DE3851458T2 (de) * 1987-04-08 1995-02-09 Hitachi Ltd Vorrichtung mit einer scheideförmigen Durchflusszelle.
JPS63262565A (ja) * 1987-04-20 1988-10-28 Hitachi Ltd フロ−セル
US4845025A (en) * 1987-11-10 1989-07-04 Coulter Corporation Biological sample mixing apparatus and method
JPH0224535A (ja) * 1988-07-12 1990-01-26 Canon Inc 粒子解析装置
JPH0718785B2 (ja) * 1988-09-19 1995-03-06 株式会社日立製作所 フローセル装置
US4981580A (en) * 1989-05-01 1991-01-01 Coulter Corporation Coincidence arbitration in a flow cytomery sorting system
JPH0353164A (ja) * 1989-07-20 1991-03-07 Canon Inc サンプル供給装置及びこれを用いたサンプル測定装置
US5005981A (en) * 1989-09-08 1991-04-09 Becton, Dickinson And Company Apparatus for method for causing vortices in a test tube
US5215376A (en) * 1989-09-08 1993-06-01 Becton, Dickinson And Company Method for causing vortices in a test tube
EP0418026B1 (de) * 1989-09-13 1994-11-30 Kabushiki Kaisha Tiyoda Seisakusho Gerät zur Zellenvorbehandlung für Durchfluss-Zytometrie
JP3049254B2 (ja) * 1990-02-08 2000-06-05 シスメックス株式会社 ２種類の光源を備えた光学式粒子分析装置
JPH0716392B2 (ja) * 1990-06-20 1995-03-01 株式会社ピーシーシーテクノロジー 細胞融合及び融合細胞選別システム
JPH0710226B2 (ja) * 1990-06-20 1995-02-08 株式会社ピーシーシーテクノロジー プロトプラスト攪拌装置並びにそれを含む細胞融合装置及びフローサイトメーター装置
JP2939647B2 (ja) * 1990-07-24 1999-08-25 シスメックス株式会社 フローイメージングサイトメータにおける自動焦点調整方法
US5259593A (en) * 1990-08-30 1993-11-09 University Of Southern California Apparatus for droplet stream manufacturing
JP2874746B2 (ja) * 1990-11-22 1999-03-24 シスメックス株式会社 フローイメージングサイトメータにおけるフローセル機構
JP3121849B2 (ja) * 1991-02-27 2001-01-09 シスメックス株式会社 フローイメージサイトメータ
JPH0734012B2 (ja) * 1991-02-27 1995-04-12 東亜医用電子株式会社 フローイメージサイトメータ
US5144224A (en) * 1991-04-01 1992-09-01 Larsen Lawrence E Millimeter wave flow cytometer
US5199576A (en) * 1991-04-05 1993-04-06 University Of Rochester System for flexibly sorting particles
US5412466A (en) * 1991-07-26 1995-05-02 Toa Medical Electronics Co., Ltd. Apparatus for forming flattened sample flow for analyzing particles
US5370842A (en) * 1991-11-29 1994-12-06 Canon Kabushiki Kaisha Sample measuring device and sample measuring system
US5359907A (en) * 1992-11-12 1994-11-01 Horiba Instruments, Inc. Method and apparatus for dry particle analysis

Also Published As

Publication number Publication date
DE69532416T2 (de) 2004-12-02
JPH10507524A (ja) 1998-07-21
AU3958295A (en) 1996-05-06
WO1996012171A2 (en) 1996-04-25
EP0786078A2 (de) 1997-07-30
EP0786078B1 (de) 2004-01-07
AU698929B2 (en) 1998-11-12
US6133044A (en) 2000-10-17
WO1996012171A3 (en) 1996-08-01

Similar Documents

Publication Publication Date Title
DE69532416D1 (de) Methode und vorrichtung zur tröpfchenerzeugung mit hoher rate bei der durchfluss-cytometrie
DE69628542D1 (de) Verfahren und vorrichtung zur durchflusscytometrie
DE69414006D1 (de) Vorrichtung und methode zur verbesserung des rückspülens mit gas in seitlichen unterdrainagesystemen
DE69530957D1 (de) Verfahren zur Sättigung mit einem flüssigen Mittel, Vorrichtung und Artikel
DE69006980D1 (de) Vorrichtung zur Steuerung des Zwischenraumes zwischen den Blättern bei Druckern und Verfahren zur Steuerung des Zwischenraumes.
DE69116670D1 (de) Verfahren und Vorrichtung zur Durchflussregelung
DE69634829D1 (de) Verfahren und vorrichtung zur leukozytenfiltration
DE69122637D1 (de) Verfahren und Vorrichtung zur Lebenszeichenüberwachung
DE69831082D1 (de) Verfahren und vorrichtung zur ablauffolgeplanung der rückwärtsverbindungsrate
DE69229309D1 (de) Verfahren und Vorrichtung zur Überwachung des Vorschubes in numerisch gesteuerten Systemen
DE69127609D1 (de) Vorrichtung und verfahren zur herstellung von diamanten
DE69133203D1 (de) Verfahren und vorrichtung zur kontinuierlichen volumendurchflussmessung
DE69913589D1 (de) Verfahren und Vorrichtung zur Herstellung von Linsen und mit deren hergestellte Linsen
DE69533763D1 (de) Verfahren und Vorrichtung zur automatischen Steuerung der Lautstärke in einem Kommunikationsapparat
DE69404302D1 (de) Verfahren und vorrichtung zur abgabe viskoser materialien
DE69213311D1 (de) Verfahren und Vorrichtung zur Versorgung mit Gas
DE69213967D1 (de) Verfahren und Vorrichtung zur Herstellung von faserförmigen Schleifpartikeln
DE59606677D1 (de) Verfahren und vorrichtung zur vereinheitlichten, kontinuierlichen herstellung von polyamiden
DE69516197D1 (de) Verfahren und Vorrichtung für die Versorgung mit gasförmigen Rohstoffen
DE69514454D1 (de) Verfahren und Vorrichtung zur Gastrennung mit Membranen
AT399551B (de) Ersatzrohr zum einbau in eine bestehende leitung sowie verfahren und vorrichtung zur herstellung desselben
DE69626165D1 (de) Flüssigkeitsausstosskopf, Vorrichtung zum Ausstossen von Flüssigkeit und Verfahren zur Wiederherstellung derselben
DE69008818D1 (de) Vorrichtung und verfahren zur kontinuierlichen entfernung von sauerstoff aus flüssigkeitsströmen.
DE69503114D1 (de) Verfahren und vorrichtung zur herstellung von fleischaehnlichen produkten
DE69221408D1 (de) Verfahren und Vorrichtung zur Überwachung des Vorschubes bei kreisförmigen Bahnabschnitten

Legal Events

Date Code Title Description
8364 No opposition during term of opposition