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DE69534429D1 - Verfahren und vorrichtung zur durchführung automatischer analysen - Google Patents

Verfahren und vorrichtung zur durchführung automatischer analysen

Info

Publication number
DE69534429D1
DE69534429D1 DE69534429T DE69534429T DE69534429D1 DE 69534429 D1 DE69534429 D1 DE 69534429D1 DE 69534429 T DE69534429 T DE 69534429T DE 69534429 T DE69534429 T DE 69534429T DE 69534429 D1 DE69534429 D1 DE 69534429D1
Authority
DE
Germany
Prior art keywords
housing
fluid
carrying
out automatic
prime mover
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69534429T
Other languages
English (en)
Other versions
DE69534429T2 (de
Inventor
L Chupp
E Lobban
Ran Kim
Walton Larue
Paul Stuart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/488,532 external-priority patent/US5631165A/en
Priority claimed from US08/482,678 external-priority patent/US5656499A/en
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE69534429D1 publication Critical patent/DE69534429D1/de
Publication of DE69534429T2 publication Critical patent/DE69534429T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1081—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
    • G01N35/109—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with two horizontal degrees of freedom
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/30—Injector mixers
    • B01F25/31—Injector mixers in conduits or tubes through which the main component flows
    • B01F25/313—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced in the centre of the conduit
    • B01F25/3132—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced in the centre of the conduit by using two or more injector devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/30—Injector mixers
    • B01F25/31—Injector mixers in conduits or tubes through which the main component flows
    • B01F25/313—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced in the centre of the conduit
    • B01F25/3132—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced in the centre of the conduit by using two or more injector devices
    • B01F25/31324—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced in the centre of the conduit by using two or more injector devices arranged concentrically
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/0092—Scheduling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1004—Cleaning sample transfer devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/10—Devices for withdrawing samples in the liquid or fluent state
    • G01N1/14—Suction devices, e.g. pumps; Ejector devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/012—Red blood cells
    • G01N2015/014—Reticulocytes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/018—Platelets
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G01N2015/1413—Hydrodynamic focussing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00356—Holding samples at elevated temperature (incubation)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00524—Mixing by agitating sample carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1032—Dilution or aliquotting
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices

Landscapes

  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Optical Measuring Cells (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
DE69534429T 1994-08-01 1995-07-28 Verfahren und vorrichtung zur durchführung automatischer analysen Expired - Lifetime DE69534429T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US28337994A 1994-08-01 1994-08-01
US283379 1994-08-01
US488532 1995-06-07
US08/488,532 US5631165A (en) 1994-08-01 1995-06-07 Method for performing automated hematology and cytometry analysis
US482678 1995-06-07
US08/482,678 US5656499A (en) 1994-08-01 1995-06-07 Method for performing automated hematology and cytometry analysis
PCT/US1995/009555 WO1996004544A1 (en) 1994-08-01 1995-07-28 Method and apparatus for performing automated analysis

Publications (2)

Publication Number Publication Date
DE69534429D1 true DE69534429D1 (de) 2005-10-13
DE69534429T2 DE69534429T2 (de) 2006-06-22

Family

ID=27403380

Family Applications (4)

Application Number Title Priority Date Filing Date
DE69527292T Expired - Lifetime DE69527292T2 (de) 1994-08-01 1995-07-28 Pseudo-telezentrischer optischer aufbau für ein durchflusszytometrisches analysegerät für blutzellen
DE69535807T Expired - Lifetime DE69535807D1 (de) 1994-08-01 1995-07-28 Vorrichtung und Verfahren zur Vorbereitung einer Flüssigkeit
DE69532045T Expired - Lifetime DE69532045T2 (de) 1994-08-01 1995-07-28 Verfahren und Vorrichtung zur Vorbereitung einer Flüssigkeit
DE69534429T Expired - Lifetime DE69534429T2 (de) 1994-08-01 1995-07-28 Verfahren und vorrichtung zur durchführung automatischer analysen

Family Applications Before (3)

Application Number Title Priority Date Filing Date
DE69527292T Expired - Lifetime DE69527292T2 (de) 1994-08-01 1995-07-28 Pseudo-telezentrischer optischer aufbau für ein durchflusszytometrisches analysegerät für blutzellen
DE69535807T Expired - Lifetime DE69535807D1 (de) 1994-08-01 1995-07-28 Vorrichtung und Verfahren zur Vorbereitung einer Flüssigkeit
DE69532045T Expired - Lifetime DE69532045T2 (de) 1994-08-01 1995-07-28 Verfahren und Vorrichtung zur Vorbereitung einer Flüssigkeit

Country Status (9)

Country Link
US (1) US5631730A (de)
EP (4) EP1356859B1 (de)
JP (3) JP2963541B2 (de)
AT (4) ATE220200T1 (de)
AU (2) AU3235095A (de)
CA (2) CA2193971C (de)
DE (4) DE69527292T2 (de)
ES (4) ES2311659T3 (de)
WO (2) WO1996004543A1 (de)

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ATE304170T1 (de) 2005-09-15
EP0774112B1 (de) 2002-07-03
DE69532045T2 (de) 2004-07-08
ES2311659T3 (es) 2009-02-16
EP0810026B1 (de) 2003-10-29
EP0774113A1 (de) 1997-05-21
JPH10160730A (ja) 1998-06-19
EP0810026A1 (de) 1997-12-03
WO1996004543A1 (en) 1996-02-15
DE69534429T2 (de) 2006-06-22
CA2193971C (en) 2000-10-31
JP2863511B2 (ja) 1999-03-03
WO1996004544A1 (en) 1996-02-15
JPH09508703A (ja) 1997-09-02
AU3235095A (en) 1996-03-04
DE69527292D1 (de) 2002-08-08
DE69527292T2 (de) 2003-02-27
US5631730A (en) 1997-05-20
EP0774113B1 (de) 2005-09-07
ES2210426T3 (es) 2004-07-01
JP2963541B2 (ja) 1999-10-18
CA2193971A1 (en) 1996-02-15
ATE252938T1 (de) 2003-11-15
CA2192835A1 (en) 1996-02-15
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AU3271895A (en) 1996-03-04
ATE220200T1 (de) 2002-07-15
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EP0774112A1 (de) 1997-05-21
ES2180650T3 (es) 2003-02-16
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DE69532045D1 (de) 2003-12-04

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