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DE69534923D1 - Anabolische zubereitung für knochenmasse enthaltend olpadronat - Google Patents

Anabolische zubereitung für knochenmasse enthaltend olpadronat

Info

Publication number
DE69534923D1
DE69534923D1 DE69534923T DE69534923T DE69534923D1 DE 69534923 D1 DE69534923 D1 DE 69534923D1 DE 69534923 T DE69534923 T DE 69534923T DE 69534923 T DE69534923 T DE 69534923T DE 69534923 D1 DE69534923 D1 DE 69534923D1
Authority
DE
Germany
Prior art keywords
olpadronate
bone mass
mass containing
anabolic
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69534923T
Other languages
English (en)
Other versions
DE69534923T2 (de
Inventor
Socrates Papapoulos
Jose Luis Ferretti
Rafael Labriola
Nelida Mondelo
Emilio J A Roldan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gador SA
Universiteit Leiden
Original Assignee
Gador SA
Universiteit Leiden
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gador SA, Universiteit Leiden filed Critical Gador SA
Application granted granted Critical
Publication of DE69534923D1 publication Critical patent/DE69534923D1/de
Publication of DE69534923T2 publication Critical patent/DE69534923T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69534923T 1994-12-28 1995-12-27 Anabolische zubereitung für knochenmasse enthaltend olpadronat Expired - Lifetime DE69534923T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP94120799 1994-12-28
EP94120799 1994-12-28
PCT/EP1995/005142 WO1996019998A1 (en) 1994-12-28 1995-12-27 Bone mass anabolic composition comprising olpadronate

Publications (2)

Publication Number Publication Date
DE69534923D1 true DE69534923D1 (de) 2006-05-18
DE69534923T2 DE69534923T2 (de) 2006-11-23

Family

ID=8216571

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69534923T Expired - Lifetime DE69534923T2 (de) 1994-12-28 1995-12-27 Anabolische zubereitung für knochenmasse enthaltend olpadronat

Country Status (11)

Country Link
EP (1) EP0800397B1 (de)
JP (1) JP3796693B2 (de)
KR (1) KR100385697B1 (de)
AR (1) AR000555A1 (de)
AU (1) AU701258B2 (de)
BR (1) BR9510123A (de)
CA (1) CA2208714C (de)
DE (1) DE69534923T2 (de)
ES (1) ES2262145T3 (de)
WO (1) WO1996019998A1 (de)
ZA (1) ZA9510995B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0753523A1 (de) * 1995-07-10 1997-01-15 Gador S.A. Amino-substuierte bisphosphonsäure
DE19719680A1 (de) * 1997-05-09 1998-11-19 Boehringer Mannheim Gmbh Verwendung von Diphosphonsäuren zur präventiven Behandlung von Spätfolgen bei Harnblasenerweiterung oder Harnblasenersatz
DK0891979T3 (da) * 1997-07-15 2005-01-31 Gador Sa Krystallinsk form af N,N-dimethyl-3-amino-1-hydroxypropan-1,1-diphosphonsyre-mononatrium-monohydrat og fremgangsmåde til fremstilling heraf
AR013994A1 (es) * 1998-10-30 2001-01-31 Gador Sa Procedimiento y preparaciones que modulan selectivamente la funcion del osteoblasto para la prevencion y tratamiento de las osteopatias fragilizantes.
US6416737B1 (en) * 1998-11-19 2002-07-09 Board Of Trustees Of The University Of Arkansas Increasing bone strength with selected bisphosphonates
EP1372669B1 (de) 2001-01-23 2005-06-15 Gador S.A. Bisphosphonate-enthaltenden zusammensetzungen zur vorbeugung und/oder heilung von metabolischen knochenkrankheiten, verfahren zu ihren herstellung und benutzung dieser zusammensetzungen
RU2387451C2 (ru) 2002-05-10 2010-04-27 Ф.Хоффманн-Ля Рош Аг Бисфосфоновые кислоты, предназначенные для лечения и профилактики остеопороза
WO2008157050A1 (en) * 2007-06-19 2008-12-24 Albemarle Corporation Processes for manufacturing bisphosphonic acids

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE114473T1 (de) * 1984-04-30 1994-12-15 Procter & Gamble Ausrüstung für die verwendung bei der behandlung von osteoporose.
EP0573604B1 (de) * 1991-02-26 1995-03-15 PROCTER & GAMBLE PHARMACEUTICALS, INC. (an Ohio corp.) Behandlungsmethoden für osteoporose
WO1993011786A1 (en) * 1991-12-17 1993-06-24 Procter & Gamble Pharmaceuticals, Inc. Methods for the treatment of osteoporosis using bisphosphonates and parathyroid hormone
EP0648120B1 (de) * 1992-06-30 1997-12-29 PROCTER & GAMBLE PHARMACEUTICALS, INC. Verwendung von phosphinate zur behandlung der osteoporose
EP0600834A1 (de) * 1992-11-30 1994-06-08 Ciba-Geigy Ag Verwendung von Methanbiphosphonsäurederivaten zur Herstellung eines Arzneimittels zur Behandlung von Knochenbrüchen
US5366965A (en) * 1993-01-29 1994-11-22 Boehringer Mannheim Gmbh Regimen for treatment or prophylaxis of osteoporosis

Also Published As

Publication number Publication date
KR100385697B1 (ko) 2003-08-21
EP0800397A1 (de) 1997-10-15
DE69534923T2 (de) 2006-11-23
EP0800397B1 (de) 2006-04-05
CA2208714C (en) 2003-10-21
AU701258B2 (en) 1999-01-21
CA2208714A1 (en) 1996-07-04
BR9510123A (pt) 1997-12-30
AU4434796A (en) 1996-07-19
ES2262145T3 (es) 2006-11-16
JP3796693B2 (ja) 2006-07-12
WO1996019998A1 (en) 1996-07-04
JPH11502506A (ja) 1999-03-02
ZA9510995B (en) 1997-06-30
AR000555A1 (es) 1997-07-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition