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DE69600928C5 - Kapillar-mikroküvette - Google Patents

Kapillar-mikroküvette Download PDF

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Publication number
DE69600928C5
DE69600928C5 DE69600928T DE69600928T DE69600928C5 DE 69600928 C5 DE69600928 C5 DE 69600928C5 DE 69600928 T DE69600928 T DE 69600928T DE 69600928 T DE69600928 T DE 69600928T DE 69600928 C5 DE69600928 C5 DE 69600928C5
Authority
DE
Germany
Prior art keywords
microcuvette
channel
recess
base body
inner peripheral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69600928T
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English (en)
Other versions
DE69600928T2 (de
DE69600928D1 (de
Inventor
Anders Williamsson
Stefan Wahlqvist
Sven-Erik Nilsson
Jan Lilja
Lars Jansson
Bertil Nilsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hemocue AB
Original Assignee
Hemocue AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26662277&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69600928(C5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hemocue AB filed Critical Hemocue AB
Publication of DE69600928D1 publication Critical patent/DE69600928D1/de
Publication of DE69600928T2 publication Critical patent/DE69600928T2/de
Application granted granted Critical
Publication of DE69600928C5 publication Critical patent/DE69600928C5/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0825—Test strips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0321—One time use cells, e.g. integrally moulded
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Optical Measuring Cells (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Micromachines (AREA)
  • Electron Tubes For Measurement (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

Einstückige kapillare Mikroküvette (1) zur Messung chemischer Blutwerte, die einen Grundkörper (2) und eine die Blutprobe aufnehmende Ausnehmung (3) mit einem Messbereich (4) in dem Grundkörper aufweist, wobei die Ausnehmung (3) definiert ist durch zwei einander gegenüberliegende, im Wesentlichen parallele innere Oberflächen (5, 6) des Grundkörpers (2), einen äußeren Umfangsrand (7) mit einem Probeneinlass (8) am äußeren Ende der Mikroküvette, wobei der Umfangsrand (7) vom Probeneinlass (8) ausgehend schräg nach hinten verläuft, und einen inneren Umfangsbereich (9) mit einem Kanal (10) von höherer Kapillarkraft als der Messbereich (4), wobei beide Enden des Kanals (10) mit der Umgebung der Mikroküvette (1) in Verbindung stehen und dieser Kanal (10) durch eine innere Endwand dieses inneren Umfangsbereichs (9) und zwei im wesentlichen ebene Oberflächen dieses Grundkörpers definiert ist und sich der Abstand zwischen den beiden im wesentlichen ebenen Oberflächen dieses Grundkörpers (2) in Richtung weg von dieser inneren Endwand dieses inneren Umfangsbereichs...

Description

  • Tenor
  • Der Xa-Zivilsenat des Bundesgerichtshofs hat auf die mündliche Verhandlung vom 25. November 2010 für Recht erkannt:
    Auf die Berufung der Beklagten wird das am 2. Mai 2007 verkündete Urteil des 4. Senats (Nichtigkeitssenats) des Bundespatent gerichts unter Abweisung der weitergehenden Klage abgeändert.
    Das europäische Patent 821 784 wird mit Wirkung für die Bundesrepublik Deutschland dadurch teilweise für nichtig erklärt, dass der nicht angegriffene Patentanspruch 3 in seiner Rückbeziehung über Patentanspruch 2 auf Patentanspruch 1 in der Fassung des erteilten Patents bestehen bleibt und an die Stelle der angegriffenen Patentansprüche 1, 2 sowie 4 bis 8 folgende Patentansprüche treten:

Claims (5)

  1. Einstückige kapillare Mikroküvette (1) zur Messung chemischer Blutwerte, die einen Grundkörper (2) und eine die Blutprobe aufnehmende Ausnehmung (3) mit einem Messbereich (4) in dem Grundkörper aufweist, wobei die Ausnehmung (3) definiert ist durch zwei einander gegenüberliegende, im Wesentlichen parallele innere Oberflächen (5, 6) des Grundkörpers (2), einen äußeren Umfangsrand (7) mit einem Probeneinlass (8) am äußeren Ende der Mikroküvette, wobei der Umfangsrand (7) vom Probeneinlass (8) ausgehend schräg nach hinten verläuft, und einen inneren Umfangsbereich (9) mit einem Kanal (10) von höherer Kapillarkraft als der Messbereich (4), wobei beide Enden des Kanals (10) mit der Umgebung der Mikroküvette (1) in Verbindung stehen und dieser Kanal (10) durch eine innere Endwand dieses inneren Umfangsbereichs (9) und zwei im wesentlichen ebene Oberflächen dieses Grundkörpers definiert ist und sich der Abstand zwischen den beiden im wesentlichen ebenen Oberflächen dieses Grundkörpers (2) in Richtung weg von dieser inneren Endwand dieses inneren Umfangsbereichs (9) vergrößert.
  2. Mikroküvette (1) nach Anspruch 1, wobei diese Ausnehmung (3) ein vorgegebenes Volumen aufweist.
  3. Mikroküvette (1) nach Anspruch 1, wobei diese Ausnehmung (3) ein trockenes Reagenz in vorgegebener Menge enthält.
  4. Mikroküvette (1) nach Anspruch 1 zur Verwendung bei der Bestimmung des Hämoglobingehalts von unverdünntem Vollblut, wobei dieser Messbereich eine Tiefe aufweist, die 0,15 mm nicht übersteigt.
  5. Mikroküvette (1) nach Anspruch 4, wobei der Hämoglobingehalt nach dem Azidmethämoglobin-Verfahren bestimmt wird.
DE69600928T 1995-04-21 1996-04-18 Kapillar-mikroküvette Expired - Lifetime DE69600928C5 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE9501460A SE504193C2 (sv) 1995-04-21 1995-04-21 Kapillär mikrokyvett
SE9501460 1995-04-21
US08/429,494 US5674457A (en) 1995-04-21 1995-04-26 Capillary microcuvette
PCT/SE1996/000504 WO1996033399A1 (en) 1995-04-21 1996-04-18 Capillary microcuvette

Publications (3)

Publication Number Publication Date
DE69600928D1 DE69600928D1 (de) 1998-12-10
DE69600928T2 DE69600928T2 (de) 1999-03-18
DE69600928C5 true DE69600928C5 (de) 2011-07-28

Family

ID=26662277

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69600928T Expired - Lifetime DE69600928C5 (de) 1995-04-21 1996-04-18 Kapillar-mikroküvette
DE29623464U Expired - Lifetime DE29623464U1 (de) 1995-04-21 1996-04-18 Kapillare Mikroküvette

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE29623464U Expired - Lifetime DE29623464U1 (de) 1995-04-21 1996-04-18 Kapillare Mikroküvette

Country Status (11)

Country Link
US (1) US5674457A (de)
EP (1) EP0821784B1 (de)
JP (1) JP2941063B2 (de)
CN (1) CN1111732C (de)
AU (1) AU5412296A (de)
DE (2) DE69600928C5 (de)
DK (1) DK0821784T3 (de)
ES (1) ES2125107T3 (de)
SE (1) SE504193C2 (de)
WO (1) WO1996033399A1 (de)
ZA (1) ZA963147B (de)

Families Citing this family (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9602237D0 (sv) * 1996-06-05 1996-06-05 Bertil Nilsson Colour indicator
SE521120C2 (sv) 1997-10-03 2003-09-30 Hemocue Ab Framställning av mikrokyvetter
SE9800070D0 (sv) * 1998-01-14 1998-01-14 Hemocue Ab Blandningsmetod
JP2002529729A (ja) 1998-11-05 2002-09-10 シェモメテック・アクティーゼルスカブ 粒子の検査方法ならびに該方法に使用する系およびデバイス
USD433150S (en) * 1998-11-24 2000-10-31 Hemocue Ab Microcuvette
USD445909S1 (en) 1999-11-11 2001-07-31 Hemocue Ab Cuvette
US6406919B1 (en) 1999-12-16 2002-06-18 Biosafe Laboratories, Inc. Whole blood collection device and method
JP3621617B2 (ja) * 2000-01-21 2005-02-16 ブラザー工業株式会社 グルコース濃度測定用のキャピラリー装置、グルコース濃度の非侵襲的モニター方法及び血糖値の非侵襲的モニター方法
SE518539C2 (sv) 2000-06-28 2002-10-22 Migrata U K Ltd Sätt och kyvett för kvantitativ hemoglobinbestämning i outspätt helblod
US7029628B2 (en) 2000-12-28 2006-04-18 Stat-Chem Inc. Portable co-oximeter
US20020160520A1 (en) * 2001-03-16 2002-10-31 Phoenix Bioscience Silicon nano-collection analytic device
US6678542B2 (en) 2001-08-16 2004-01-13 Optiscan Biomedical Corp. Calibrator configured for use with noninvasive analyte-concentration monitor and employing traditional measurements
US6989891B2 (en) 2001-11-08 2006-01-24 Optiscan Biomedical Corporation Device and method for in vitro determination of analyte concentrations within body fluids
US7050157B2 (en) * 2001-11-08 2006-05-23 Optiscan Biomedical Corp. Reagent-less whole-blood glucose meter
SE0104443D0 (sv) 2001-12-28 2001-12-28 Hemocue Ab Analysis method and cuvette therefor
US20040132167A1 (en) * 2003-01-06 2004-07-08 Peter Rule Cartridge lance
US20040132168A1 (en) * 2003-01-06 2004-07-08 Peter Rule Sample element for reagentless whole blood glucose meter
US20050106749A1 (en) * 2003-04-15 2005-05-19 Braig James R. Sample element for use in material analysis
JP4861830B2 (ja) * 2003-12-24 2012-01-25 グライコフィ， インコーポレイテッド 糖タンパク質の産生において、グリカンのマンノシルリン酸化を除去する方法
CN1957254B (zh) * 2004-04-07 2012-01-25 沃德劳有限合伙公司 用于分析生物流体的可置换腔
WO2005111580A1 (en) * 2004-05-07 2005-11-24 Optiscan Biomedical Corporation Sample element with fringing-reduction capabilities
US7238535B2 (en) * 2004-09-01 2007-07-03 World Properties, Inc. Test cell for evaluating phosphor
US7224448B2 (en) * 2004-11-16 2007-05-29 Agilent Technologies, Inc. Apparatus and methods for evaluating an optical property of a liquid sample
US20060235348A1 (en) 2005-02-14 2006-10-19 Callicoat David N Method of extracting and analyzing the composition of bodily fluids
US20060203236A1 (en) * 2005-03-08 2006-09-14 Zhenghua Ji Sample cell
SE528697C2 (sv) * 2005-03-11 2007-01-30 Hemocue Ab Volymetrisk bestämning av antalet vita blodkroppar i ett blodprov
SE529643C3 (sv) * 2005-07-08 2007-11-06 Hemocue Ab En kuvett och en metod och ett verktyg för tillverkning därav
US7842247B2 (en) 2005-08-19 2010-11-30 Canadian Blood Services Sample holder for dynamic light scattering
US7277167B2 (en) * 2005-09-13 2007-10-02 Agilent Technologies, Inc. Modular cuvettes and methods for use thereof
US9561001B2 (en) 2005-10-06 2017-02-07 Optiscan Biomedical Corporation Fluid handling cassette system for body fluid analyzer
US20070081159A1 (en) * 2005-10-11 2007-04-12 Giffin Kristin M Apparatus and methods for evaluating an optical property of a liquid sample
US7731901B2 (en) * 2005-10-19 2010-06-08 Abbott Laboratories Apparatus and method for performing counts within a biologic fluid sample
US7918975B2 (en) 2005-11-17 2011-04-05 Abbott Diabetes Care Inc. Analytical sensors for biological fluid
US7763453B2 (en) 2005-11-30 2010-07-27 Micronics, Inc. Microfluidic mixing and analytic apparatus
US9056291B2 (en) 2005-11-30 2015-06-16 Micronics, Inc. Microfluidic reactor system
SE531233C2 (sv) * 2006-03-28 2009-01-27 Hemocue Ab Anordning och förfarande för detektion av fluorecensmärkta biologiska komponenter
USD562988S1 (en) * 2006-03-29 2008-02-26 Hemocue Ab Cuvette
SE530244C2 (sv) * 2006-05-05 2008-04-08 Hemocue Ab Förfarande och system för kvantitativ hemoglobinbestämning
DE102006025477B4 (de) * 2006-05-30 2009-01-15 Ekf - Diagnostic Gmbh Küvette und Verfahren zu ihrer Herstellung
AU2007265628B2 (en) 2006-06-23 2012-12-06 Revvity Health Sciences, Inc. Methods and devices for microfluidic point-of-care immunoassays
SE531041C2 (sv) * 2006-07-17 2008-11-25 Hemocue Ab Räkning av trombocyter
US20080084559A1 (en) * 2006-10-10 2008-04-10 C Technologies, Inc. Microvolume sampling device
US7738094B2 (en) 2007-01-26 2010-06-15 Becton, Dickinson And Company Method, system, and compositions for cell counting and analysis
DE102008039810B3 (de) * 2008-08-25 2010-04-08 Ekf - Diagnostic Gmbh Einmal-Mikroküvette zur Bestimmung des Hämoglobingehalts in Vollblut
KR101147534B1 (ko) * 2009-06-02 2012-05-21 주식회사 인포피아 시료 채취 및 주입 기구
US9554742B2 (en) 2009-07-20 2017-01-31 Optiscan Biomedical Corporation Fluid analysis system
US8731638B2 (en) 2009-07-20 2014-05-20 Optiscan Biomedical Corporation Adjustable connector and dead space reduction
CN106110923A (zh) 2009-12-18 2016-11-16 艾博特健康公司 生物流体样本分析卡盒
EP2528687B1 (de) 2010-01-29 2018-08-22 Micronics, Inc. System beinhaltend ein wirtinstrument und eine mikrofluidische kartusche für untersuchungen
WO2011156522A1 (en) 2010-06-09 2011-12-15 Optiscan Biomedical Corporation Measuring analytes in a fluid sample drawn from a patient
US10114020B2 (en) 2010-10-11 2018-10-30 Mbio Diagnostics, Inc. System and device for analyzing a fluidic sample
US9522396B2 (en) 2010-12-29 2016-12-20 S.D. Sight Diagnostics Ltd. Apparatus and method for automatic detection of pathogens
EP2658653B1 (de) 2010-12-30 2015-03-04 Abbott Point Of Care, Inc. Kassette zur analyse biologischer proben mit probebehandlungsteil und analysekammerteil
WO2013006716A1 (en) 2011-07-06 2013-01-10 Optiscan Biomedical Corporation Sample cell for fluid analysis system
KR101215006B1 (ko) 2011-08-16 2012-12-24 바디텍메드 주식회사 이중 채취수단을 갖는 모세관 마이크로 큐베트
CN103890590B (zh) 2011-08-24 2016-03-09 艾博特健康公司 生物流体样品分析盒
WO2013075031A1 (en) 2011-11-16 2013-05-23 Becton, Dickinson And Company Methods and systems for detecting an analyte in a sample
BR112014016072B1 (pt) 2011-12-29 2021-01-12 Sight Diagnostics Ltd. método e sistema para detectar uma infecção por plasmodium em uma amostra de sangue
CN104136123B (zh) 2012-01-09 2017-03-01 精密公司 微流体反应器系统
RU2496104C1 (ru) * 2012-02-17 2013-10-20 Закрытое акционерное общество Научно-производственное предприятие "ТЕХНОМЕДИКА" Оптический картридж
EP2911791A4 (de) 2012-10-29 2016-11-02 Mbio Diagnostics Inc Biopartikelidentifikationssystem, kartusche und zugehörige verfahren
WO2014089120A1 (en) 2012-12-07 2014-06-12 Integrated Plasmonics Corporation Plasmonic spectroscopic sensor and cuvette therefor
KR20150097764A (ko) 2012-12-21 2015-08-26 마이크로닉스 인코포레이티드. 휴대형 형광 검출 시스템 및 미량분석 카트리지
WO2014100743A2 (en) 2012-12-21 2014-06-26 Micronics, Inc. Low elasticity films for microfluidic use
KR102102123B1 (ko) 2012-12-21 2020-04-20 퍼킨엘머 헬스 사이언시즈, 아이엔씨. 유체 공학 회로 및 관련 제조 방법
US9976963B2 (en) 2012-12-21 2018-05-22 Integrated Plasmonics Corporation Microcuvette cartridge
BR112015010695B1 (pt) 2013-01-11 2023-03-07 Becton, Dickinson And Company Dispositivo microfluídico e método para realizar um ensaio de uma amostra líquida, método para formar um dispositivo microfluídico, sistema e kit
FR3003033B1 (fr) * 2013-03-07 2015-04-17 Commissariat Energie Atomique Dispositif de prelevement d'un echantillon de liquide par capillarite et procede d'analyse associe
US10481089B2 (en) 2013-03-12 2019-11-19 Integrated Plasmonics Corporation Optical detection system with tilted sensor
US9995623B2 (en) 2013-03-14 2018-06-12 Integrated Plasmonics Corporation Ambient light assisted spectroscopy
US9784986B2 (en) 2013-03-14 2017-10-10 Integrated Plasmonics Corporation Self-aligned spatial filter
EP2994543B1 (de) 2013-05-07 2018-08-15 Micronics, Inc. Vorrichtung zur herstellung und analyse von nukleinsäuren
CN105189750B (zh) 2013-05-07 2020-07-28 珀金埃尔默健康科学有限公司 使用粘土矿物和碱性溶液制备含核酸样品的方法
US10386377B2 (en) 2013-05-07 2019-08-20 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
EP2999988A4 (de) 2013-05-23 2017-01-11 S.D. Sight Diagnostics Ltd. Verfahren und system zur bildgebung einer zellprobe
IL227276A0 (en) 2013-07-01 2014-03-06 Parasight Ltd A method and system for obtaining a monolayer of cells, for use specifically for diagnosis
CN105659151B (zh) 2013-08-26 2018-06-29 思迪赛特诊断有限公司 数码显微系统与方法
WO2015035420A1 (en) 2013-09-09 2015-03-12 University Of Florida Research Foundation, Inc. Point of care sickle cell test
CN113477149B (zh) 2013-11-06 2023-09-12 贝克顿·迪金森公司 微流体性装置和制造和使用其的方法
US10018640B2 (en) 2013-11-13 2018-07-10 Becton, Dickinson And Company Optical imaging system and methods for using the same
CN104655568A (zh) * 2013-11-21 2015-05-27 达尔生技股份有限公司 微型比色皿
EP3186778B1 (de) 2014-08-27 2023-01-11 S.D. Sight Diagnostics Ltd. System und verfahren zur berechnung der fokusvariation für ein digitales mikroskop
CA3130077A1 (en) 2014-10-14 2016-04-21 Becton, Dickinson And Company Blood sample management using open cell foam
US11298061B2 (en) 2014-10-14 2022-04-12 Becton, Dickinson And Company Blood sample management using open cell foam
WO2016115397A1 (en) * 2015-01-14 2016-07-21 Hartley Frank Thomas Apparatus for drawing of a bodily fluid and method therefor
FR3033407B1 (fr) 2015-03-02 2017-03-31 Avalun Dispositif de prelevement d'un echantillon liquide par capillarite.
CN107636445A (zh) 2015-03-09 2018-01-26 加州理工学院 中红外高光谱的光谱系统及其方法
BR112017002312B1 (pt) 2015-03-10 2022-06-28 Becton, Dickinson And Company Dispositivo de coleta de fluido biológico
WO2017040650A1 (en) 2015-09-01 2017-03-09 Becton, Dickinson And Company Depth filtration device for separating specimen phases
CN108474934B (zh) 2015-09-17 2022-01-18 思迪赛特诊断有限公司 用于检测身体样本中实体的方法和设备
US11733150B2 (en) 2016-03-30 2023-08-22 S.D. Sight Diagnostics Ltd. Distinguishing between blood sample components
EP4177593A1 (de) 2016-05-11 2023-05-10 S.D. Sight Diagnostics Ltd. Probenträger für optische messungen
BR112018072627A2 (pt) 2016-05-11 2019-02-19 S D Sight Diagnostics Ltd realização de medições óticas em uma amostra
GB2555403B (en) * 2016-10-24 2021-03-24 Entia Ltd A Cuvette
US11067526B2 (en) 2017-08-17 2021-07-20 Abbott Point Of Care Inc. Devices, systems, and methods for performing optical and electrochemical assays
USD870315S1 (en) * 2017-11-09 2019-12-17 Hemocue Ab Cuvette
US11921272B2 (en) 2017-11-14 2024-03-05 S.D. Sight Diagnostics Ltd. Sample carrier for optical measurements
US11433390B2 (en) 2017-12-07 2022-09-06 Ion Llc Methods and systems for a capillary device
CN108240973A (zh) * 2018-01-23 2018-07-03 江苏康尚生物医疗科技有限公司 一种全血血红蛋白浓度检测方法及装置
CN113557415B (zh) 2019-02-06 2024-12-20 加州理工学院 紧凑型高光谱中红外光谱仪
CN111912771A (zh) * 2019-05-09 2020-11-10 磐创精准(北京)生物科技有限公司 一种免疫检测联合白细胞计数的同步检测装置及其检测方法
CN111912764B (zh) * 2019-05-09 2025-08-22 苏州中科苏净生物技术有限公司 一种细胞计数分型用微流控芯片及其取样方法
CN111912766A (zh) * 2019-05-09 2020-11-10 磐创精准(北京)生物科技有限公司 免疫检测与细胞分析用组合检测卡及联合检测方法
CN111912770A (zh) * 2019-05-09 2020-11-10 磐创精准(北京)生物科技有限公司 一种手持式白细胞计数仪及白细胞计数方法
WO2021092579A1 (en) 2019-11-08 2021-05-14 California Institute Of Technology Infrared spectrometer having dielectric-polymer-based spectral filter
EP4073492A1 (de) 2019-12-12 2022-10-19 S.D. Sight Diagnostics Ltd. Analyse eines analyten in einem medium
EP4073566B1 (de) 2019-12-12 2025-04-23 S.D. Sight Diagnostics Ltd. Künstliche erzeugung eines farbigen blutausstrichbildes
US11191460B1 (en) 2020-07-15 2021-12-07 Shani Biotechnologies LLC Device and method for measuring blood components
EP3974809A1 (de) 2020-09-29 2022-03-30 Bioanalyt GmbH Mikroküvette
CN119137485A (zh) * 2022-05-13 2024-12-13 株式会社普欧威盖特 流体器件
USD1060722S1 (en) * 2023-06-14 2025-02-04 Hemocue Ab Microcuvette
IT202300014922A1 (it) * 2023-07-17 2025-01-17 Univ Bologna Alma Mater Studiorum Microcella elettrochimica

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2062588A (en) * 1934-03-30 1936-12-01 Gilbert & Barker Mfg Co Oil tester
US2059374A (en) * 1934-03-30 1936-11-03 Gilbert & Barker Mfg Co Oil tester
US2015949A (en) * 1934-07-28 1935-10-01 Maw Frank James Slide for testing liquids
US2056791A (en) * 1934-10-17 1936-10-06 Gilbert & Barker Mfg Co Fluid sample holder
US2069374A (en) * 1935-01-16 1937-02-02 Emilio J Lagomarsino Beverage cooler
US3363503A (en) * 1963-10-07 1968-01-16 Beckman Instruments Inc Micro-volume sample cells
US3501242A (en) * 1967-11-06 1970-03-17 Perkin Elmer Corp Pivoting sample cell holder
US3565537A (en) * 1968-10-30 1971-02-23 Jack Fielding Specimen holder for example for testing the colour of a liquid such as blood
FR2035058A1 (de) * 1969-03-19 1970-12-18 American Optical Corp
US3705000A (en) * 1971-06-01 1972-12-05 American Optical Corp Liquid sample holder for a photometer
US3814522A (en) * 1973-02-28 1974-06-04 American Hospital Supply Corp Specimen tube for microscopic examination
FR2232776B1 (de) * 1973-06-05 1976-06-25 Eastman Kodak Co
SE399768B (sv) * 1975-09-29 1978-02-27 Lilja Jan E Kyvett for provtagning, blandning av, provet med ett reagensmedel och direkt utforande av, serskilt optisk, analys av det med reagensmedlet blandade provet
US4405235A (en) * 1981-03-19 1983-09-20 Rossiter Val J Liquid cell for spectroscopic analysis
US4596695A (en) * 1984-09-10 1986-06-24 Cottingham Hugh V Agglutinographic reaction chamber
US4756884A (en) * 1985-08-05 1988-07-12 Biotrack, Inc. Capillary flow device
US4761381A (en) * 1985-09-18 1988-08-02 Miles Inc. Volume metering capillary gap device for applying a liquid sample onto a reactive surface
US4746215A (en) * 1986-04-24 1988-05-24 Pacific Scientific Company Particle counter air inlet assembly
US4865812A (en) * 1987-02-03 1989-09-12 Davstar Industries, Inc. Integral specimen collection tube and microscope slide device
CA1315181C (en) * 1987-04-13 1993-03-30 Joel M. Blatt Test strip device with volume metering capillary gap
US4981654A (en) * 1988-05-06 1991-01-01 Davstar Industries, Inc. Unitary centrifuge tube and separable dispensing receptacle
JPH0217426A (ja) * 1988-07-05 1990-01-22 Kiyouseki Seihin Gijutsu Kenkyusho:Kk 液体試料用の分析セル
US5030421A (en) * 1988-08-31 1991-07-09 Davstar Industries, Inc. Integral centrifuge tube and specimen slide
US4957582A (en) * 1989-03-16 1990-09-18 Eastman Kodak Company Capillary transport zone coated with adhesive
AU642444B2 (en) * 1989-11-30 1993-10-21 Mochida Pharmaceutical Co., Ltd. Reaction vessel
US5260032A (en) * 1991-12-27 1993-11-09 Davstar California, Inc. Integral centrifuge tube and specimen slide

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SE9501460L (sv) 1996-10-22
ES2125107T3 (es) 1999-02-16
CN1168173A (zh) 1997-12-17
SE504193C2 (sv) 1996-12-02
WO1996033399A1 (en) 1996-10-24
EP0821784B1 (de) 1998-11-04
EP0821784A1 (de) 1998-02-04
DE69600928T2 (de) 1999-03-18
DK0821784T3 (da) 1999-07-12
US5674457A (en) 1997-10-07
DE69600928D1 (de) 1998-12-10
SE9501460D0 (sv) 1995-04-21
JP2941063B2 (ja) 1999-08-25
CN1111732C (zh) 2003-06-18
DE29623464U1 (de) 1998-08-27
ZA963147B (en) 1996-10-25
JPH10507837A (ja) 1998-07-28
AU5412296A (en) 1996-11-07

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