DE69706146D1 - Taxoide, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen - Google Patents

Taxoide, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen

Info

Publication number: DE69706146D1
Authority: DE; Germany
Prior art keywords: taxoids; production; pharmaceutical compositions; compositions containing; pharmaceutical
Prior art date: 1996-03-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE69706146T

Other languages

English (en)

Other versions

DE69706146T2 (de

Inventor

Herve Bouchard

Jean-Dominique Bourzat

Alain Commercon

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Aventis Pharma SA

Original Assignee

Aventis Pharma SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-03-06

Filing date

1997-03-05

Publication date

2001-09-20

1997-03-05 Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA

2001-09-20 Application granted granted Critical

2001-09-20 Publication of DE69706146D1 publication Critical patent/DE69706146D1/de

2002-05-02 Publication of DE69706146T2 publication Critical patent/DE69706146T2/de

2017-03-06 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines Containing Plant Substances (AREA)

DE69706146T 1996-03-06 1997-03-05 Taxoide, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen Expired - Fee Related DE69706146T2 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9602804A FR2745814B1 (fr)	1996-03-06	1996-03-06	Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR1997/000386 WO1997032869A1 (fr)	1996-03-06	1997-03-05	Taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number	Publication Date
DE69706146D1 true DE69706146D1 (de)	2001-09-20
DE69706146T2 DE69706146T2 (de)	2002-05-02

Family

ID=9489910

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69706146T Expired - Fee Related DE69706146T2 (de)	1996-03-06	1997-03-05	Taxoide, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen

Country Status (34)

Country	Link
US (1)	US6160135A (de)
EP (1)	EP0885208B1 (de)
JP (1)	JP2000506158A (de)
KR (1)	KR19990087398A (de)
CN (1)	CN1210525A (de)
AP (1)	AP1023A (de)
AT (1)	ATE204266T1 (de)
AU (1)	AU715228B2 (de)
BG (1)	BG63693B1 (de)
BR (1)	BR9707887A (de)
CA (1)	CA2248195A1 (de)
CZ (1)	CZ283498A3 (de)
DE (1)	DE69706146T2 (de)
DK (1)	DK0885208T3 (de)
EA (1)	EA001516B1 (de)
EE (1)	EE03611B1 (de)
ES (1)	ES2161446T3 (de)
FR (1)	FR2745814B1 (de)
GE (1)	GEP20012517B (de)
GR (1)	GR3036410T3 (de)
HU (1)	HUP9902425A3 (de)
IL (1)	IL125998A (de)
IS (1)	IS4809A (de)
NO (1)	NO983472D0 (de)
NZ (1)	NZ331040A (de)
OA (1)	OA10855A (de)
PL (1)	PL328691A1 (de)
PT (1)	PT885208E (de)
SK (1)	SK121598A3 (de)
TR (1)	TR199801732T2 (de)
TW (1)	TW474928B (de)
WO (1)	WO1997032869A1 (de)
YU (1)	YU38398A (de)
ZA (1)	ZA971746B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5973160A (en)	1992-12-23	1999-10-26	Poss; Michael A.	Methods for the preparation of novel sidechain-bearing taxanes
US6372780B2 (en)	1995-03-27	2002-04-16	Aventis Pharma S.A.	Methods of treating cell lines expressing multidrug resistance P-glycoprotein
MA23823A1 (fr)	1995-03-27	1996-10-01	Aventis Pharma Sa	Nouveaux taxoides, leur preparation et les compositions qui les contiennent
CA2314071A1 (en) *	1997-12-19	1999-07-01	Kabushiki Kaisha Yakult Honsha	Taxane derivatives
EP1020188A1 (de) *	1999-01-13	2000-07-19	Aventis Pharma S.A.	Neue Verwendung von Taxoid-Derivaten
CO5280224A1 (es) *	2000-02-02	2003-05-30	Univ Florida State Res Found	Taxanos sustituidos con ester en c7, utiles como agentes antitumorales y composiciones farmaceuticas que los contienen
GEP20043239B (en)	2000-02-02	2004-05-25	Florida State Univ Research Foundation Us	C10 Carbonate Substituted Taxanes as Antitumor Agents
CZ2003837A3 (cs)	2000-09-22	2004-12-15	Bristol-Myers Squibb Company	Způsob pro snížení toxicity při kombinovaných chemoterapiích
FR2859996B1 (fr) *	2003-09-19	2006-02-03	Aventis Pharma Sa	Solvat acetonique du dimethoxy docetaxel et son procede de preparation
SV2006002036A (es)	2004-03-05	2006-03-16	Univ Florida State Res Found	Taxanos con sustituyente lactiloxilo en el c7
AU2008288651A1 (en) *	2007-08-22	2009-02-26	6570763 Canada Inc.	Process for converting 9-dihydro-13-acetylbaccatin III into docetaxel or paclitaxel
FR2926551A1 (fr) *	2008-01-17	2009-07-24	Aventis Pharma Sa	Formes cristallines du dimethoxy docetaxel et leurs procedes de preparation
SG10201810928SA (en)	2009-10-29	2019-01-30	Aventis Pharma Sa	Novel antitumoral use of cabazitaxel
CN104650012A (zh) *	2013-11-22	2015-05-27	天士力控股集团有限公司	一种紫杉烷类化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5136060A (en) *	1989-11-14	1992-08-04	Florida State University	Method for preparation of taxol using an oxazinone
EP0555485A4 (en) *	1991-07-17	1993-11-03	Nippon Steel Corporation	Antitumor compound nsc-lsc1 and production thereof
CA2100808A1 (en) *	1992-10-01	1994-04-02	Vittorio Farina	Deoxy paclitaxels
PT689436E (pt) *	1993-03-22	2004-04-30	Univ Florida State	Taxanos que nao possuem um grupo oxo em c-9 e composicoes farmaceuticas que os contem
FR2711369B1 (fr) *	1993-10-20	1995-11-17	Rhone Poulenc Rorer Sa	Nouveaux taxoïdes, leur préparation et les compositions qui les contiennent.
CN1073105C (zh) *	1994-07-26	2001-10-17	因迪纳有限公司	具有抗肿瘤活性的半合成紫杉烷
US6201140B1 (en) *	1994-07-28	2001-03-13	Bristol-Myers Squibb Company	7-0-ethers of taxane derivatives

1996
- 1996-03-06 FR FR9602804A patent/FR2745814B1/fr not_active Expired - Fee Related
1997
- 1997-02-26 TW TW086102360A patent/TW474928B/zh active
- 1997-02-27 ZA ZA9701746A patent/ZA971746B/xx unknown
- 1997-03-05 IL IL12599897A patent/IL125998A/en not_active IP Right Cessation
- 1997-03-05 JP JP9531523A patent/JP2000506158A/ja active Pending
- 1997-03-05 AU AU20302/97A patent/AU715228B2/en not_active Ceased
- 1997-03-05 EE EE9800264A patent/EE03611B1/xx not_active IP Right Cessation
- 1997-03-05 WO PCT/FR1997/000386 patent/WO1997032869A1/fr not_active Application Discontinuation
- 1997-03-05 NZ NZ331040A patent/NZ331040A/en unknown
- 1997-03-05 DE DE69706146T patent/DE69706146T2/de not_active Expired - Fee Related
- 1997-03-05 TR TR1998/01732T patent/TR199801732T2/xx unknown
- 1997-03-05 SK SK1215-98A patent/SK121598A3/sk unknown
- 1997-03-05 EP EP97908304A patent/EP0885208B1/de not_active Expired - Lifetime
- 1997-03-05 AP APAP/P/1998/001335A patent/AP1023A/en active
- 1997-03-05 US US09/117,659 patent/US6160135A/en not_active Expired - Fee Related
- 1997-03-05 PT PT97908304T patent/PT885208E/pt unknown
- 1997-03-05 GE GEAP19974503A patent/GEP20012517B/en unknown
- 1997-03-05 CN CN97192042A patent/CN1210525A/zh active Pending
- 1997-03-05 AT AT97908304T patent/ATE204266T1/de not_active IP Right Cessation
- 1997-03-05 HU HU9902425A patent/HUP9902425A3/hu unknown
- 1997-03-05 DK DK97908304T patent/DK0885208T3/da active
- 1997-03-05 PL PL97328691A patent/PL328691A1/xx unknown
- 1997-03-05 ES ES97908304T patent/ES2161446T3/es not_active Expired - Lifetime
- 1997-03-05 EA EA199800795A patent/EA001516B1/ru not_active IP Right Cessation
- 1997-03-05 KR KR1019980706814A patent/KR19990087398A/ko not_active Withdrawn
- 1997-03-05 BR BR9707887-5A patent/BR9707887A/pt unknown
- 1997-03-05 CA CA002248195A patent/CA2248195A1/fr not_active Abandoned
- 1997-03-05 CZ CZ982834A patent/CZ283498A3/cs unknown
1998
- 1998-07-24 IS IS4809A patent/IS4809A/is unknown
- 1998-07-28 NO NO983472A patent/NO983472D0/no not_active Application Discontinuation
- 1998-09-03 YU YU38398A patent/YU38398A/sh unknown
- 1998-09-04 OA OA9800161A patent/OA10855A/fr unknown
- 1998-09-04 BG BG102753A patent/BG63693B1/bg unknown
2001
- 2001-08-20 GR GR20010400596T patent/GR3036410T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU2030297A (en)	1997-09-22
PT885208E (pt)	2001-11-30
WO1997032869A1 (fr)	1997-09-12
NZ331040A (en)	2000-02-28
IL125998A (en)	2002-02-10
EE9800264A (et)	1999-02-15
CZ283498A3 (cs)	1999-01-13
PL328691A1 (en)	1999-02-15
AU715228B2 (en)	2000-01-20
ES2161446T3 (es)	2001-12-01
BG63693B1 (bg)	2002-09-30
CN1210525A (zh)	1999-03-10
EE03611B1 (et)	2002-02-15
HUP9902425A3 (en)	2001-08-28
FR2745814A1 (fr)	1997-09-12
BR9707887A (pt)	1999-09-21
BG102753A (en)	1999-09-30
EA001516B1 (ru)	2001-04-23
JP2000506158A (ja)	2000-05-23
TW474928B (en)	2002-02-01
AP1023A (en)	2001-11-16
HUP9902425A2 (hu)	2001-04-28
AP9801335A0 (en)	1998-09-30
EA199800795A1 (ru)	1999-02-25
GR3036410T3 (en)	2001-11-30
NO983472L (no)	1998-07-28
KR19990087398A (ko)	1999-12-27
EP0885208B1 (de)	2001-08-16
OA10855A (fr)	2003-02-05
ATE204266T1 (de)	2001-09-15
EP0885208A1 (de)	1998-12-23
DK0885208T3 (da)	2001-10-15
FR2745814B1 (fr)	1998-04-03
GEP20012517B (en)	2001-08-27
ZA971746B (en)	1997-09-16
SK121598A3 (en)	1999-01-11
IL125998A0 (en)	1999-04-11
DE69706146T2 (de)	2002-05-02
IS4809A (is)	1998-07-24
US6160135A (en)	2000-12-12
TR199801732T2 (xx)	1998-12-21
CA2248195A1 (fr)	1997-09-12
YU38398A (sh)	1999-07-28
NO983472D0 (no)	1998-07-28

Publication	Publication Date	Title
ATE188471T1 (de)	2000-01-15	Taxal derivate, deren herstellung und diese enthaltende pharmazeutische zusammensetzung
DE69928260D1 (de)	2005-12-15	Schwefel-substituierte sulfonylaminocarbonsäure n-arylamide, ihre herstellung, ihre anwendung und diese enthaltende pharmazeutische zusammensetzungen
DE69630145D1 (de)	2003-10-30	Taxal derivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen
DE59905572D1 (de)	2003-06-18	Substituierte 4-amino-2-aryl-pyrimidine, ihre herstellung, ihre verwendung und sie enthaltende pharmazeutische präparate
DK0747050T4 (da)	2013-05-21	Farmaceutiske sammensætninger, der indeholder irbesartan
DE60138872D1 (de)	2009-07-16	Azetidinderivate, ihre herstellung und sie enthaltende pharmazeutische zusammensetzungen
ATA188592A (de)	1995-12-15	Alkyl-bisacylphosphinoxide, diese enthaltende zusammensetzungen und ihre verwendung
ATE164843T1 (de)	1998-04-15	Naphthalinderivate, ihre herstellungsverfahren und zwischenprodukte dafür, und diese enthaltende pharmazeutische zusammensetzungen
KR100547921B1 (ko)	2006-10-19	설폰아미드-치환된크로만,이의제조방법및이를포함하는약제학적조성물
DE69715009D1 (de)	2002-10-02	Substituierte thiazolidinedione derivate, ihre herstellung und pharmazeutische zusammensetzungen, die sie enthalten
DE69706146D1 (de)	2001-09-20	Taxoide, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen
DE69608680D1 (de)	2000-07-06	Taxal derivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen
EE9900034A (et)	1999-08-16	Arüültsükloalkaankarboksüülestrid, nende kasutamine, farmatseutilised kompositsioonid ja valmistamine
FR2712288B1 (fr)	1996-01-05	Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
DE69610085D1 (de)	2000-10-05	Taxol derivate,deren herstellung und diese enthaltende pharmazeutische zusammenstellungen
ATE252096T1 (de)	2003-11-15	Prolylendopeptidase-inhibitoren, ihre herstellung und ihre pharmazeutische verwendung
EP0672052A1 (de)	1995-09-20	Tachyquinin antagonisten, ihre herstellung und ihre verwendung in pharmazeutischen formulierungen.
TR199501082A2 (tr)	1996-06-21	Farmasötik formülasyonlar.
FR2721023B1 (fr)	1996-07-12	Nouveaux Taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
DE68914700D1 (de)	1994-05-26	Polymere Zusammensetzungen und ihre Herstellung.
DE69614568D1 (de)	2001-09-20	Neue taxoide, herstellung und pharmazeutische zusammensetzungen diese enthaltend
DE69311463D1 (de)	1997-07-17	Pfropfpolymerteilchen, herstellung davon, und diese enthaltende zusammensetzung
DE69509621D1 (de)	1999-06-17	Diarylheptanoidderivat und diese enthaltende pharmazeutische Zusammensetzung
FR2711370B1 (fr)	1996-01-05	Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
ATE157360T1 (de)	1997-09-15	Thienocyclopentanonoximether, ihre herstellung und diese enthaltende arzneimittel

Legal Events

Date	Code	Title	Description
2002-09-12	8364	No opposition during term of opposition
2004-01-15	8339	Ceased/non-payment of the annual fee