DE69721497D1 - Multifunktionelle formulierung für fettabsorbierung und zur senkung des cholesterolgehaltes im blut, welche chitosan und nicotinsäure enthält - Google Patents
Multifunktionelle formulierung für fettabsorbierung und zur senkung des cholesterolgehaltes im blut, welche chitosan und nicotinsäure enthältInfo
- Publication number
- DE69721497D1 DE69721497D1 DE69721497T DE69721497T DE69721497D1 DE 69721497 D1 DE69721497 D1 DE 69721497D1 DE 69721497 T DE69721497 T DE 69721497T DE 69721497 T DE69721497 T DE 69721497T DE 69721497 D1 DE69721497 D1 DE 69721497D1
- Authority
- DE
- Germany
- Prior art keywords
- nicotinic acid
- blood
- reducing
- acid
- chitosan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 title abstract 6
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title abstract 4
- 229920001661 Chitosan Polymers 0.000 title abstract 3
- 238000009472 formulation Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 229960003512 nicotinic acid Drugs 0.000 title abstract 3
- 235000001968 nicotinic acid Nutrition 0.000 title abstract 3
- 239000011664 nicotinic acid Substances 0.000 title abstract 3
- 235000012000 cholesterol Nutrition 0.000 title abstract 2
- 238000010521 absorption reaction Methods 0.000 title 1
- 239000008280 blood Substances 0.000 title 1
- 210000004369 blood Anatomy 0.000 title 1
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 abstract 2
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 abstract 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 abstract 2
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 abstract 1
- 102000015779 HDL Lipoproteins Human genes 0.000 abstract 1
- 108010010234 HDL Lipoproteins Proteins 0.000 abstract 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 235000010323 ascorbic acid Nutrition 0.000 abstract 1
- 229960005070 ascorbic acid Drugs 0.000 abstract 1
- 239000011668 ascorbic acid Substances 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 235000020958 biotin Nutrition 0.000 abstract 1
- 229960002685 biotin Drugs 0.000 abstract 1
- 239000011616 biotin Substances 0.000 abstract 1
- 210000001072 colon Anatomy 0.000 abstract 1
- 229960000304 folic acid Drugs 0.000 abstract 1
- 235000019152 folic acid Nutrition 0.000 abstract 1
- 239000011724 folic acid Substances 0.000 abstract 1
- 210000002429 large intestine Anatomy 0.000 abstract 1
- 229940055726 pantothenic acid Drugs 0.000 abstract 1
- 235000019161 pantothenic acid Nutrition 0.000 abstract 1
- 239000011713 pantothenic acid Substances 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
- 229940088594 vitamin Drugs 0.000 abstract 1
- 235000013343 vitamin Nutrition 0.000 abstract 1
- 239000011782 vitamin Substances 0.000 abstract 1
- 229930003231 vitamin Natural products 0.000 abstract 1
- -1 vitamin acids Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US601388 | 1996-02-14 | ||
| US08/601,388 US5736532A (en) | 1996-02-14 | 1996-02-14 | Multifunctional fat absorption and blood cholesterol reducing formulation comprising chitosan |
| PCT/US1997/001635 WO1997029760A1 (en) | 1996-02-14 | 1997-02-04 | Multifunctional fat absorption and blood cholesterol reducing formulation containing chitosan and nicotinic acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69721497D1 true DE69721497D1 (de) | 2003-06-05 |
| DE69721497T2 DE69721497T2 (de) | 2004-03-18 |
Family
ID=24407295
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69721497T Expired - Fee Related DE69721497T2 (de) | 1996-02-14 | 1997-02-04 | Multifunktionelle formulierung für fettabsorbierung und zur senkung des cholesterolgehaltes im blut, welche chitosan und nicotinsäure enthält |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5736532A (de) |
| EP (1) | EP0881903B1 (de) |
| JP (1) | JP2000504724A (de) |
| AT (1) | ATE238805T1 (de) |
| AU (1) | AU1852597A (de) |
| DE (1) | DE69721497T2 (de) |
| ES (1) | ES2199342T3 (de) |
| ID (1) | ID15895A (de) |
| WO (1) | WO1997029760A1 (de) |
| ZA (1) | ZA971134B (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69917784T2 (de) | 1998-07-30 | 2004-12-02 | Vital Living, Inc., Phoenix | Flüssige chitosan-enthaltende zusammensetzungen und verfahren zur herstellung und verwendung |
| GB9920393D0 (en) * | 1999-08-27 | 1999-11-03 | Medix Scient Uk Limited | Plant extract mixtures and their uses |
| AU2002321707A1 (en) * | 2001-08-08 | 2003-02-24 | Paolina Galvao | Pharmaceutical enteric coated composition comprising chitosan |
| US6897348B2 (en) | 2001-12-19 | 2005-05-24 | Kimberly Clark Worldwide, Inc | Bandage, methods of producing and using same |
| US7419655B2 (en) * | 2002-09-11 | 2008-09-02 | Kimberly-Clark Worldwide, Inc. | Skin care products |
| GB0302741D0 (en) * | 2003-02-06 | 2003-03-12 | Advanced Biopolymers As | Use |
| RU2232775C1 (ru) * | 2003-05-16 | 2004-07-20 | Общество с ограниченной ответственностью "Инвест-Фарм" | Способ получения ионосвязанных производных олигосахарида хитозана |
| US20070116713A1 (en) * | 2005-11-22 | 2007-05-24 | Gill Robert P | Compositions and methods for reducing or controlling blood cholesterol, lipoproteins, triglycerides and atherosclerosis |
| KR100882611B1 (ko) * | 2006-11-14 | 2009-02-12 | 주식회사 키토라이프 | 표적 리간드로서 폴릭산이 도입된 유전자 전달체용저분자량 수용성 키토산 나노입자 및 이의 제조방법 |
| US7659313B2 (en) * | 2007-09-13 | 2010-02-09 | Gateway Health Alliances, Inc. | Methods and related compositions using specific indanes to reduce weight and inhibit lipase, α-amylase and α-glucosidase activity in mammals |
| CN102469782A (zh) | 2010-06-18 | 2012-05-23 | 哈洛资源公司 | 包含壳聚糖的固态共混物的制剂及方法 |
| PT2861229T (pt) * | 2012-06-15 | 2021-01-05 | Conaris Res Institute Ag | Uma composição farmacêutica que contém ácido nicotínico e/ou nicotinamida e/ou triptofano para influenciar positivamente a microbiota intestinal |
| DK3079675T3 (da) | 2013-12-13 | 2020-04-20 | Conaris Res Institute Ag | Farmaceutisk sammensætning indeholdende nikotinsyre og/eller nikotinamid til anvendelse til gavnlig påvirkning af blodlipidniveauer ved modificering af tarmmikrobiataen |
| WO2015086838A2 (en) * | 2013-12-13 | 2015-06-18 | Conaris Research Institute Ag | A pharmaceutical composition containing combinations of nicotinamide and 5-aminosalicylic acid for beneficially influencing the intestinal microbiota and/or treating gastrointestinal inflammation |
| ITUA20161937A1 (it) * | 2016-03-23 | 2017-09-23 | S I I T S R L Servizio Int Imballaggi Termosaldanti | Preparazione per il controllo del peso corporeo a base di chitosano e cellulosa |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4223023A (en) * | 1978-10-12 | 1980-09-16 | Ivan Furda | Nonabsorbable lipid binder |
| US4946870A (en) * | 1986-06-06 | 1990-08-07 | Union Carbide Chemicals And Plastics Company Inc. | Delivery systems for pharmaceutical or therapeutic actives |
| US5300494A (en) * | 1986-06-06 | 1994-04-05 | Union Carbide Chemicals & Plastics Technology Corporation | Delivery systems for quaternary and related compounds |
| JP2667351B2 (ja) * | 1992-03-24 | 1997-10-27 | 麒麟麦酒株式会社 | 食餌脂質消化吸収阻害剤および飲食品 |
| US5420197A (en) * | 1994-01-13 | 1995-05-30 | Hydromer, Inc. | Gels formed by the interaction of polyvinylpyrrolidone with chitosan derivatives |
-
1996
- 1996-02-14 US US08/601,388 patent/US5736532A/en not_active Expired - Lifetime
-
1997
- 1997-02-04 WO PCT/US1997/001635 patent/WO1997029760A1/en active IP Right Grant
- 1997-02-04 DE DE69721497T patent/DE69721497T2/de not_active Expired - Fee Related
- 1997-02-04 AT AT97904162T patent/ATE238805T1/de not_active IP Right Cessation
- 1997-02-04 AU AU18525/97A patent/AU1852597A/en not_active Abandoned
- 1997-02-04 ES ES97904162T patent/ES2199342T3/es not_active Expired - Lifetime
- 1997-02-04 EP EP97904162A patent/EP0881903B1/de not_active Expired - Lifetime
- 1997-02-04 JP JP9529372A patent/JP2000504724A/ja active Pending
- 1997-02-06 ID IDP970367A patent/ID15895A/id unknown
- 1997-02-11 ZA ZA9701134A patent/ZA971134B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000504724A (ja) | 2000-04-18 |
| EP0881903B1 (de) | 2003-05-02 |
| ID15895A (id) | 1997-08-14 |
| ZA971134B (en) | 1997-08-25 |
| US5736532A (en) | 1998-04-07 |
| AU1852597A (en) | 1997-09-02 |
| ATE238805T1 (de) | 2003-05-15 |
| ES2199342T3 (es) | 2004-02-16 |
| WO1997029760A1 (en) | 1997-08-21 |
| DE69721497T2 (de) | 2004-03-18 |
| EP0881903A1 (de) | 1998-12-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |