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DE69727483D1 - Gewebetransplantat aus der magensubmukosa zur reparatur neurologischen gewebes - Google Patents

Gewebetransplantat aus der magensubmukosa zur reparatur neurologischen gewebes

Info

Publication number
DE69727483D1
DE69727483D1 DE69727483T DE69727483T DE69727483D1 DE 69727483 D1 DE69727483 D1 DE 69727483D1 DE 69727483 T DE69727483 T DE 69727483T DE 69727483 T DE69727483 T DE 69727483T DE 69727483 D1 DE69727483 D1 DE 69727483D1
Authority
DE
Germany
Prior art keywords
tissue
submukosa
magic
transplant
repairing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69727483T
Other languages
English (en)
Other versions
DE69727483T2 (de
Inventor
A Cobb
F Badylak
Gary Isom
Archana Sharma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Purdue Research Foundation
Original Assignee
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation filed Critical Purdue Research Foundation
Publication of DE69727483D1 publication Critical patent/DE69727483D1/de
Application granted granted Critical
Publication of DE69727483T2 publication Critical patent/DE69727483T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/38—Stomach; Intestine; Goblet cells; Oral mucosa; Saliva
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0679—Cells of the gastro-intestinal tract
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Nutrition Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Prostheses (AREA)
DE69727483T 1996-09-16 1997-09-16 Gewebetransplantat aus der magensubmukosa zur reparatur neurologischen gewebes Expired - Lifetime DE69727483T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2619796P 1996-09-16 1996-09-16
US26197P 1996-09-16
PCT/US1997/016294 WO1998010775A1 (en) 1996-09-16 1997-09-16 Composition and method for repairing neurological tissue

Publications (2)

Publication Number Publication Date
DE69727483D1 true DE69727483D1 (de) 2004-03-11
DE69727483T2 DE69727483T2 (de) 2004-11-25

Family

ID=21830422

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69727483T Expired - Lifetime DE69727483T2 (de) 1996-09-16 1997-09-16 Gewebetransplantat aus der magensubmukosa zur reparatur neurologischen gewebes
DE69739928T Expired - Lifetime DE69739928D1 (de) 1996-09-16 1997-09-16 Gewebetransplantat aus der Magensubmukosa zur Reparatur neurologischen Gewebes

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69739928T Expired - Lifetime DE69739928D1 (de) 1996-09-16 1997-09-16 Gewebetransplantat aus der Magensubmukosa zur Reparatur neurologischen Gewebes

Country Status (9)

Country Link
US (1) US6241981B1 (de)
EP (1) EP0925067B1 (de)
JP (1) JP4572009B2 (de)
AU (1) AU731768B2 (de)
CA (1) CA2263898C (de)
DE (2) DE69727483T2 (de)
DK (1) DK0925067T3 (de)
ES (1) ES2213835T3 (de)
WO (1) WO1998010775A1 (de)

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US20020095218A1 (en) 1996-03-12 2002-07-18 Carr Robert M. Tissue repair fabric
AU742457B2 (en) 1996-08-23 2002-01-03 Cook Biotech, Incorporated Graft prosthesis, materials and methods
US6666892B2 (en) 1996-08-23 2003-12-23 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
JP4606583B2 (ja) 1998-06-05 2011-01-05 オルガノジェネシス インク． 生物工学的手法による平面シート状移植補綴
DE69940507D1 (de) * 1998-06-05 2009-04-16 Organogenesis Inc Biotechnisch erzeugte gefässprothese für die implantation
CA2334368C (en) 1998-06-05 2011-05-24 Organogenesis, Inc. Bioengineered tubular graft prostheses
WO1999062427A1 (en) * 1998-06-05 1999-12-09 Organogenesis Inc. Bioengineered vascular graft support prostheses
US6448076B2 (en) 1998-09-15 2002-09-10 The Regents Of The University Of Michigan Method for chemically acellularizing a biological tissue sample
US8882850B2 (en) 1998-12-01 2014-11-11 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
AU761153B2 (en) * 1998-12-01 2003-05-29 Purdue Research Foundation Method for vocal cord reconstruction
US6918396B1 (en) 1998-12-01 2005-07-19 Purdue Research Foundation Method for vocal cord reconstruction
EP1320390A2 (de) * 2000-09-18 2003-06-25 Organogenesis Inc. Bioartifizielle flache schichtförmige prothesen und ihre verwendung
DE10146903C1 (de) * 2001-09-24 2002-11-14 Cytonet Gmbh & Co Kg Verfahren zur Herstellung von in vitro-Hohlorganen
US20100254900A1 (en) * 2002-03-18 2010-10-07 Campbell Phil G Biocompatible polymers and Methods of use
US8529956B2 (en) 2002-03-18 2013-09-10 Carnell Therapeutics Corporation Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
ATE472938T1 (de) * 2002-05-02 2010-07-15 Purdue Research Foundation Transplantatkonstrukte mit verbesserter vaskularisierung
EP1503652A4 (de) * 2002-05-02 2006-02-08 Purdue Research Foundation Durch vaskularisierung verstärkte prothesenkonstrukte
CA2483913C (en) * 2002-05-02 2014-07-15 Purdue Research Foundation Vascularization enhanced graft constructs comprising basement membrane
US7326571B2 (en) 2003-07-17 2008-02-05 Boston Scientific Scimed, Inc. Decellularized bone marrow extracellular matrix
US20050125049A1 (en) * 2003-10-21 2005-06-09 The Regents Of The University Of Michigan Tissue engineered vascular construct and method for producing same
GB2430626B (en) * 2004-02-09 2008-09-24 Cook Biotech Inc Stent graft devices having collagen coating
WO2006050459A2 (en) * 2004-10-28 2006-05-11 Cook Incorporated Methods and systems for modifying vascular valves
US20060292227A1 (en) * 2005-06-23 2006-12-28 Mcpherson Timothy B Extracellular matrix material particles and methods of preparation
WO2007126411A2 (en) 2005-07-28 2007-11-08 Carnegie Mellon University Biocompatible polymers and methods of use
CN1903144A (zh) * 2005-07-29 2007-01-31 广东冠昊生物科技有限公司 生物型人工韧带及其制备方法
CN1903143A (zh) * 2005-07-29 2007-01-31 广东冠昊生物科技有限公司 生物型人工血管及其制备方法
CN100482178C (zh) * 2005-08-04 2009-04-29 广东冠昊生物科技有限公司 带生物膜的血管瘤夹
CN1986001B (zh) * 2005-12-20 2011-09-14 广东冠昊生物科技股份有限公司 生物护创膜
CN1986006A (zh) * 2005-12-20 2007-06-27 广州知光生物科技有限公司 生物型神经导管
CN1985778B (zh) * 2005-12-20 2010-10-13 广东冠昊生物科技股份有限公司 生物型人工角膜
CN1986007B (zh) * 2005-12-20 2011-09-14 广东冠昊生物科技股份有限公司 生物型外科补片
CN101332314B (zh) * 2008-07-22 2012-11-14 广东冠昊生物科技股份有限公司 生物型关节软骨修补件
US20100023129A1 (en) * 2008-07-22 2010-01-28 Guo-Feng Xu Jawbone prosthesis and method of manufacture
CN101332316B (zh) * 2008-07-22 2012-12-26 广东冠昊生物科技股份有限公司 生物型鼻梁植入体
US8529961B2 (en) 2006-10-17 2013-09-10 Carmell Therapeutics Corporation Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
WO2008097906A2 (en) * 2007-02-02 2008-08-14 The Regents Of The University Of Michigan System and method for forming bone, ligament and bone-ligament constructs
WO2008109407A2 (en) 2007-03-02 2008-09-12 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Extracellular matrix-derived gels and related methods
US8257434B2 (en) * 2007-12-18 2012-09-04 Cormatrix Cardiovascular, Inc. Prosthetic tissue valve
US8679176B2 (en) 2007-12-18 2014-03-25 Cormatrix Cardiovascular, Inc Prosthetic tissue valve
US8735054B1 (en) 2008-01-04 2014-05-27 Lifecell Corporation Acellular tissue matrix preservation solution
US9150318B1 (en) 2009-01-02 2015-10-06 Lifecell Corporation Method for sterilizing an acellular tissue matrix
DK2398502T3 (en) * 2009-02-18 2015-11-23 Cormatrix Cardiovascular Inc FORMATIONS AND PROCESSES FOR PREVENTING cardiac arrhythmia
US20100267143A1 (en) * 2009-04-16 2010-10-21 Snu R&Db Foundation Method for Surface Modification of Polymeric Scaffold for Stem Cell Transplantation Using Decellularized Extracellular Matrix
US8845719B2 (en) 2011-05-27 2014-09-30 Cormatrix Cardiovascular, Inc Extracellular matrix material conduits and methods of making and using same
US9011368B2 (en) * 2013-09-25 2015-04-21 Amanda C. Rivera-Begeman Methods for improving cerebrospinal fluid flow
US9878071B2 (en) 2013-10-16 2018-01-30 Purdue Research Foundation Collagen compositions and methods of use
CA2943182A1 (en) 2014-03-21 2015-09-24 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods for preparation of a terminally sterilized hydrogel derived from extracellular matrix
ES3027646T3 (en) 2014-08-27 2025-06-16 Purdue Research Foundation Collagen-based therapeutic delivery systems
WO2016172365A1 (en) 2015-04-21 2016-10-27 Purdue Research Foundation Office Of Technology Commercialization Cell-collagen-silica composites and methods of making and using the same
US20190117837A1 (en) 2016-03-02 2019-04-25 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Matrix bound nanovesicles and their use
FR3058321B1 (fr) 2016-11-07 2020-01-31 Tbf Genie Tissulaire (Tbf) Guide implantable pour la regeneration tissulaire
JP7242553B2 (ja) 2017-01-31 2023-03-20 ジェニフィス，インコーポレイテッド 基質の調製のための方法及び組成物
KR102745611B1 (ko) 2017-03-02 2024-12-20 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 식도 염증 치료를 위한 ecm 하이드로겔
US11291688B2 (en) 2017-03-02 2022-04-05 University of Pittsburgh—of the Commonwealth System of Higher Education Extracellular matrix (ECM) hydrogel and soluble fraction thereof for the treatment of cancer
US11739291B2 (en) 2017-04-25 2023-08-29 Purdue Research Foundation 3-dimensional (3D) tissue-engineered muscle for tissue restoration
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AU2019288588B2 (en) 2018-06-21 2024-06-13 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Extracellular matrix (ECM) hydrogel as a submucosal fluid cushion
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DK0528978T3 (da) * 1990-05-16 2003-02-17 Southern Res Inst Mikrokapsler til reguleret afgivelse og deres anvendelse i stimulering af nervefibervækst
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US5711969A (en) * 1995-04-07 1998-01-27 Purdue Research Foundation Large area submucosal tissue graft constructs

Also Published As

Publication number Publication date
US6241981B1 (en) 2001-06-05
EP0925067A4 (de) 2001-05-30
CA2263898C (en) 2009-12-08
AU731768B2 (en) 2001-04-05
DE69727483T2 (de) 2004-11-25
CA2263898A1 (en) 1998-03-19
JP4572009B2 (ja) 2010-10-27
DK0925067T3 (da) 2004-05-03
DE69739928D1 (de) 2010-08-19
EP0925067A1 (de) 1999-06-30
ES2213835T3 (es) 2004-09-01
WO1998010775A1 (en) 1998-03-19
JP2001500512A (ja) 2001-01-16
EP0925067B1 (de) 2004-02-04
AU4348597A (en) 1998-04-02

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