DE69734520D1 - Nukleinsäurevermittelter elektronentransfer - Google Patents
Nukleinsäurevermittelter elektronentransferInfo
- Publication number
- DE69734520D1 DE69734520D1 DE69734520T DE69734520T DE69734520D1 DE 69734520 D1 DE69734520 D1 DE 69734520D1 DE 69734520 T DE69734520 T DE 69734520T DE 69734520 T DE69734520 T DE 69734520T DE 69734520 D1 DE69734520 D1 DE 69734520D1
- Authority
- DE
- Germany
- Prior art keywords
- nucleic acid
- complexes
- electron transfer
- reduced electron
- moieties
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000027756 respiratory electron transport chain Effects 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- PPQRONHOSHZGFQ-LMVFSUKVSA-N aldehydo-D-ribose 5-phosphate Chemical group OP(=O)(O)OC[C@@H](O)[C@@H](O)[C@@H](O)C=O PPQRONHOSHZGFQ-LMVFSUKVSA-N 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
- 229910052723 transition metal Inorganic materials 0.000 abstract 1
- 150000003624 transition metals Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6825—Nucleic acid detection involving sensors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65998796A | 1996-06-07 | 1996-06-07 | |
| PCT/US1997/009739 WO1997046568A1 (en) | 1996-06-07 | 1997-06-04 | Nucleic acid mediated electron transfer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE69734520D1 true DE69734520D1 (de) | 2005-12-08 |
Family
ID=24647650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69734520T Expired - Lifetime DE69734520D1 (de) | 1996-06-07 | 1997-06-04 | Nukleinsäurevermittelter elektronentransfer |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0923595B1 (de) |
| JP (1) | JP2000511904A (de) |
| AT (1) | ATE308553T1 (de) |
| AU (1) | AU738189B2 (de) |
| CA (1) | CA2257534A1 (de) |
| DE (1) | DE69734520D1 (de) |
| WO (1) | WO1997046568A1 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6071699A (en) | 1996-06-07 | 2000-06-06 | California Institute Of Technology | Nucleic acid mediated electron transfer |
| US5620850A (en) | 1994-09-26 | 1997-04-15 | President And Fellows Of Harvard College | Molecular recognition at surfaces derivatized with self-assembled monolayers |
| US7381525B1 (en) | 1997-03-07 | 2008-06-03 | Clinical Micro Sensors, Inc. | AC/DC voltage apparatus for detection of nucleic acids |
| US7014992B1 (en) | 1996-11-05 | 2006-03-21 | Clinical Micro Sensors, Inc. | Conductive oligomers attached to electrodes and nucleoside analogs |
| CA2229386A1 (en) * | 1997-12-16 | 1999-06-16 | The University Of Saskatchewan | Conductive metal-containing nucleic acids |
| WO1999031115A1 (en) * | 1997-12-16 | 1999-06-24 | The University Of Saskatchewan | Conductive metal-containing nucleic acids |
| US7087148B1 (en) | 1998-06-23 | 2006-08-08 | Clinical Micro Sensors, Inc. | Binding acceleration techniques for the detection of analytes |
| AU4833899A (en) * | 1998-06-24 | 2000-01-10 | Therasense, Inc. | Multi-sensor array for electrochemical recognition of nucleotide sequences and methods |
| US6740518B1 (en) | 1998-09-17 | 2004-05-25 | Clinical Micro Sensors, Inc. | Signal detection techniques for the detection of analytes |
| US6541617B1 (en) | 1998-10-27 | 2003-04-01 | Clinical Micro Sensors, Inc. | Detection of target analytes using particles and electrodes |
| US20020004593A1 (en) * | 1998-11-13 | 2002-01-10 | Thomas J. Meade | Methods of making modified nucleosides |
| DE19964220C2 (de) | 1998-11-23 | 2003-07-03 | Friz Biochem Gmbh | Verfahren zur Herstellung einer modifizierten leitfähigen Oberfläche |
| US7160869B2 (en) | 1998-12-16 | 2007-01-09 | University Of Saskatchewan | Biologically active metal-containing nucleic acids |
| DE19901761A1 (de) * | 1999-01-18 | 1999-07-01 | Gerhard Dr Hartwich | Verfahren zur elektrochemischen Detektion von Nukleinsäure-Oligomer-Hybridisierungsereignissen |
| US20020177135A1 (en) | 1999-07-27 | 2002-11-28 | Doung Hau H. | Devices and methods for biochip multiplexing |
| US7312087B2 (en) | 2000-01-11 | 2007-12-25 | Clinical Micro Sensors, Inc. | Devices and methods for biochip multiplexing |
| US6787339B1 (en) | 2000-10-02 | 2004-09-07 | Motorola, Inc. | Microfluidic devices having embedded metal conductors and methods of fabricating said devices |
| WO2003018834A2 (de) | 2001-08-25 | 2003-03-06 | Friz Biochem Gmbh | Verdrängungsassay zur detektion von nukleinsäureoligomer-hybridisierungsereignissen |
| WO2003025558A1 (fr) | 2001-09-14 | 2003-03-27 | Arkray, Inc. | Procédé, outil et dispositif de mesure d'une concentration |
| GB0205455D0 (en) | 2002-03-07 | 2002-04-24 | Molecular Sensing Plc | Nucleic acid probes, their synthesis and use |
| WO2007133703A2 (en) | 2006-05-10 | 2007-11-22 | Dxterity Diagnostics | Detection of nucleic acid targets using chemically reactive oligonucleotide probes |
| CA2757300C (en) | 2009-04-01 | 2018-01-09 | Dxterity Diagnostics Incorporated | Chemical ligation dependent probe amplification (clpa) |
| DK2710145T3 (en) | 2011-05-17 | 2016-02-22 | Dxterity Diagnostics Inc | METHOD AND COMPOSITIONS FOR THE DETECTION OF TARGET NUCLEIC ACIDS |
| EP3154696B1 (de) | 2014-06-10 | 2020-04-08 | DxTerity Diagnostics Incorporated | Vorrichtungen und verfahren zur entnahme und stabilisierung biologischer proben |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5112974A (en) * | 1985-01-18 | 1992-05-12 | The Trustees Of Columbia University In The City Of New York | Mixed ligand complexes and uses thereof as binding agents to DNA |
| JPS63238166A (ja) * | 1987-03-26 | 1988-10-04 | Mitsubishi Electric Corp | 有機電子素子材料 |
| CA2094785A1 (en) * | 1992-05-08 | 1993-11-09 | Jean Gariepy | Metal chelating peptide |
| US5591578A (en) * | 1993-12-10 | 1997-01-07 | California Institute Of Technology | Nucleic acid mediated electron transfer |
| CN1192249A (zh) * | 1995-06-27 | 1998-09-02 | 查珀尔希尔北卡罗来纳大学 | 核酸杂交的电化学检测法 |
-
1997
- 1997-06-04 DE DE69734520T patent/DE69734520D1/de not_active Expired - Lifetime
- 1997-06-04 EP EP97928853A patent/EP0923595B1/de not_active Expired - Lifetime
- 1997-06-04 AU AU33014/97A patent/AU738189B2/en not_active Ceased
- 1997-06-04 CA CA002257534A patent/CA2257534A1/en not_active Abandoned
- 1997-06-04 JP JP10500855A patent/JP2000511904A/ja not_active Ceased
- 1997-06-04 AT AT97928853T patent/ATE308553T1/de not_active IP Right Cessation
- 1997-06-04 WO PCT/US1997/009739 patent/WO1997046568A1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| AU738189B2 (en) | 2001-09-13 |
| EP0923595A1 (de) | 1999-06-23 |
| JP2000511904A (ja) | 2000-09-12 |
| EP0923595B1 (de) | 2005-11-02 |
| CA2257534A1 (en) | 1997-12-11 |
| ATE308553T1 (de) | 2005-11-15 |
| AU3301497A (en) | 1998-01-05 |
| WO1997046568A1 (en) | 1997-12-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8332 | No legal effect for de |