DE69904020D1 - Pharmazeutische zusammensetzung zur nasalen verabreichung von thiocolchicosid - Google Patents
Pharmazeutische zusammensetzung zur nasalen verabreichung von thiocolchicosidInfo
- Publication number
- DE69904020D1 DE69904020D1 DE69904020T DE69904020T DE69904020D1 DE 69904020 D1 DE69904020 D1 DE 69904020D1 DE 69904020 T DE69904020 T DE 69904020T DE 69904020 T DE69904020 T DE 69904020T DE 69904020 D1 DE69904020 D1 DE 69904020D1
- Authority
- DE
- Germany
- Prior art keywords
- thiocolchicoside
- pharmaceutical composition
- nasal delivery
- nasal
- delivery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- LEQAKWQJCITZNK-AXHKHJLKSA-N N-[(7S)-1,2-dimethoxy-10-(methylthio)-9-oxo-3-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide Chemical compound C1([C@@H](NC(C)=O)CCC2=C3)=CC(=O)C(SC)=CC=C1C2=C(OC)C(OC)=C3O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O LEQAKWQJCITZNK-AXHKHJLKSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229960000287 thiocolchicoside Drugs 0.000 title abstract 2
- 239000012729 immediate-release (IR) formulation Substances 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9801328A FR2774290B1 (fr) | 1998-02-05 | 1998-02-05 | Composition pharmaceutique pour l'administration par voie nasale de thiocolchicoside |
| FR9801328 | 1998-02-05 | ||
| PCT/FR1999/000204 WO1999039717A1 (fr) | 1998-02-05 | 1999-02-02 | Composition pharmaceutique pour l'administration par voie nasale de thiocolchicoside |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69904020D1 true DE69904020D1 (de) | 2003-01-02 |
| DE69904020T2 DE69904020T2 (de) | 2004-03-04 |
Family
ID=9522615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69904020T Expired - Lifetime DE69904020T2 (de) | 1998-02-05 | 1999-02-02 | Pharmazeutische zusammensetzung zur nasalen verabreichung von thiocolchicosid |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1052995B1 (de) |
| AT (1) | ATE227997T1 (de) |
| AU (1) | AU2169799A (de) |
| DE (1) | DE69904020T2 (de) |
| DK (1) | DK1052995T3 (de) |
| ES (1) | ES2187136T3 (de) |
| FR (1) | FR2774290B1 (de) |
| PT (1) | PT1052995E (de) |
| WO (1) | WO1999039717A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR200708925A1 (tr) | 2007-12-26 | 2009-07-21 | Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ | Kontrollü salım sağlayan flurbiprofen ve kas gevşetici kombinasyonları |
| TR201001903A2 (tr) | 2010-03-12 | 2011-04-21 | Ali̇ Rai̇f İlaç Sanayi̇ Ve Ti̇caret A.Ş. | Uzatılmış salımlı tiyokolşiklozit tablet. |
| ES2577118T3 (es) | 2013-09-12 | 2016-07-13 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Formulaciones farmacéuticas de liberación sostenida de tiocolchicósido |
| ES2577130T3 (es) | 2013-09-12 | 2016-07-13 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Nuevas formulaciones de tiocolchicósido |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1345991A (en) * | 1972-05-05 | 1974-02-06 | Roussel Uclaf | Thiocolchicine derivatives |
| IT1275955B1 (it) * | 1995-03-22 | 1997-10-24 | Dompe Spa | Formulazioni farmaceutiche in forma di gel tissotropico |
| IT1276996B1 (it) * | 1995-06-27 | 1997-11-04 | Indena Spa | Derivati della colchicina, loro uso e formulazioni che li contengono |
| IT1283110B1 (it) * | 1996-06-07 | 1998-04-07 | Indena Spa | Composti a scheletro colchicinico,loro uso come farmaci e composizioni che li contengono |
| FR2759587B1 (fr) * | 1997-02-20 | 1999-03-19 | Synthelabo | Composition pharmaceutique pour l'administration buccale de thiocolchicoside |
-
1998
- 1998-02-05 FR FR9801328A patent/FR2774290B1/fr not_active Expired - Fee Related
-
1999
- 1999-02-02 ES ES99901679T patent/ES2187136T3/es not_active Expired - Lifetime
- 1999-02-02 AU AU21697/99A patent/AU2169799A/en not_active Abandoned
- 1999-02-02 AT AT99901679T patent/ATE227997T1/de active
- 1999-02-02 EP EP99901679A patent/EP1052995B1/de not_active Expired - Lifetime
- 1999-02-02 WO PCT/FR1999/000204 patent/WO1999039717A1/fr active IP Right Grant
- 1999-02-02 DK DK99901679T patent/DK1052995T3/da active
- 1999-02-02 DE DE69904020T patent/DE69904020T2/de not_active Expired - Lifetime
- 1999-02-02 PT PT99901679T patent/PT1052995E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1052995A1 (de) | 2000-11-22 |
| AU2169799A (en) | 1999-08-23 |
| ES2187136T3 (es) | 2003-05-16 |
| WO1999039717A1 (fr) | 1999-08-12 |
| DE69904020T2 (de) | 2004-03-04 |
| ATE227997T1 (de) | 2002-12-15 |
| PT1052995E (pt) | 2003-03-31 |
| EP1052995B1 (de) | 2002-11-20 |
| DK1052995T3 (da) | 2003-03-17 |
| FR2774290B1 (fr) | 2000-06-16 |
| FR2774290A1 (fr) | 1999-08-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8332 | No legal effect for de | ||
| 8370 | Indication related to discontinuation of the patent is to be deleted | ||
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: INVERNI DELLA BEFFA S.P.A., MAILAND/MILANO, IT |
|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: SANOFI-AVENTIS S.P.A., MILANO, IT |