DE69028101D1 - Melaninkonzentrierende hormone und dns die diese expremieren - Google Patents

Melaninkonzentrierende hormone und dns die diese expremieren

Info

Publication number: DE69028101D1
Authority: DE; Germany
Prior art keywords: mch; glu; peptides; ala; rat
Prior art date: 1989-03-22
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE69028101T

Other languages

English (en)

Other versions

DE69028101T2 (de

Inventor

Joan Vaughan

Wolfgang Fischer

Jean Rivier

Jean-Louis Marie Nahon

Francoise Genevieve Presse

Wylie Vale

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Salk Institute for Biological Studies

Original Assignee

Salk Institute for Biological Studies

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-03-22

Filing date

1990-03-20

Publication date

1996-09-19

1990-03-20 Application filed by Salk Institute for Biological Studies filed Critical Salk Institute for Biological Studies

1996-09-19 Application granted granted Critical

1996-09-19 Publication of DE69028101D1 publication Critical patent/DE69028101D1/de

1997-03-06 Publication of DE69028101T2 publication Critical patent/DE69028101T2/de

2010-03-21 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

229940088597 hormone Drugs 0.000 title 1
239000005556 hormone Substances 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 7
101800002739 Melanin-concentrating hormone Proteins 0.000 abstract 6
102400001132 Melanin-concentrating hormone Human genes 0.000 abstract 6
ORRDHOMWDPJSNL-UHFFFAOYSA-N melanin concentrating hormone Chemical compound N1C(=O)C(C(C)C)NC(=O)C(CCCNC(N)=N)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CCSC)NC(=O)C(NC(=O)C(CCCNC(N)=N)NC(=O)C(NC(=O)C(NC(=O)C(N)CC(O)=O)C(C)O)CCSC)CSSCC(C(=O)NC(CC=2C3=CC=CC=C3NC=2)C(=O)NC(CCC(O)=O)C(=O)NC(C(C)C)C(O)=O)NC(=O)C2CCCN2C(=O)C(CCCNC(N)=N)NC(=O)C1CC1=CC=C(O)C=C1 ORRDHOMWDPJSNL-UHFFFAOYSA-N 0.000 abstract 5
102000004196 processed proteins & peptides Human genes 0.000 abstract 4
239000002243 precursor Substances 0.000 abstract 3
239000000055 Corticotropin-Releasing Hormone Substances 0.000 abstract 2
101500028288 Homo sapiens Melanin-concentrating hormone Proteins 0.000 abstract 2
101500025368 Rattus norvegicus Melanin-concentrating hormone Proteins 0.000 abstract 2
108020004635 Complementary DNA Proteins 0.000 abstract 1
102400000739 Corticotropin Human genes 0.000 abstract 1
101800000414 Corticotropin Proteins 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
102400000740 Melanocyte-stimulating hormone alpha Human genes 0.000 abstract 1
101710200814 Melanotropin alpha Proteins 0.000 abstract 1
206010029098 Neoplasm skin Diseases 0.000 abstract 1
108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
OOLOTUZJUBOMAX-GUBZILKMSA-N Pro-Ala-Val Chemical group [H]N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(O)=O OOLOTUZJUBOMAX-GUBZILKMSA-N 0.000 abstract 1
PMTWIUBUQRGCSB-FXQIFTODSA-N Ser-Val-Ala Chemical compound [H]N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(O)=O PMTWIUBUQRGCSB-FXQIFTODSA-N 0.000 abstract 1
208000000453 Skin Neoplasms Diseases 0.000 abstract 1
150000001413 amino acids Chemical group 0.000 abstract 1
IDLFZVILOHSSID-OVLDLUHVSA-N corticotropin Chemical compound C([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)NC(=O)[C@@H](N)CO)C1=CC=C(O)C=C1 IDLFZVILOHSSID-OVLDLUHVSA-N 0.000 abstract 1
229960000258 corticotropin Drugs 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
201000001441 melanoma Diseases 0.000 abstract 1
230000035755 proliferation Effects 0.000 abstract 1
230000028327 secretion Effects 0.000 abstract 1
208000017520 skin disease Diseases 0.000 abstract 1
241000894007 species Species 0.000 abstract 1
210000004881 tumor cell Anatomy 0.000 abstract 1
WHNFPRLDDSXQCL-UAZQEYIDSA-N α-msh Chemical compound C([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(N)=O)NC(=O)[C@H](CO)NC(C)=O)C1=CC=C(O)C=C1 WHNFPRLDDSXQCL-UAZQEYIDSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/854—Glands

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Cosmetics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DE69028101T 1989-03-22 1990-03-20 Melaninkonzentrierende hormone und dns die diese expremieren Expired - Fee Related DE69028101T2 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/326,984 US5049655A (en)	1989-03-22	1989-03-22	Melanin-concentrating hormones
PCT/US1990/001492 WO1990011295A1 (en)	1989-03-22	1990-03-20	Melanin-concentrating hormones and methods of treatment using same

Publications (2)

Publication Number	Publication Date
DE69028101D1 true DE69028101D1 (de)	1996-09-19
DE69028101T2 DE69028101T2 (de)	1997-03-06

Family

ID=23274624

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69028101T Expired - Fee Related DE69028101T2 (de)	1989-03-22	1990-03-20	Melaninkonzentrierende hormone und dns die diese expremieren

Country Status (8)

Country	Link
US (3)	US5049655A (de)
EP (1)	EP0464105B1 (de)
JP (1)	JP2944202B2 (de)
AT (1)	ATE141288T1 (de)
CA (1)	CA2046900C (de)
DE (1)	DE69028101T2 (de)
DK (1)	DK0464105T3 (de)
WO (1)	WO1990011295A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5849708A (en) *	1995-06-06	1998-12-15	Joslin Diabetes Center, Inc.	Promotion of eating behavior
US6346510B1 (en)	1995-10-23	2002-02-12	The Children's Medical Center Corporation	Therapeutic antiangiogenic endostatin compositions
AU1802000A (en) *	1998-12-28	2000-07-24	Takeda Chemical Industries Ltd.	Screening method
GB9924351D0 (en) *	1999-10-14	1999-12-15	Brennan Frank	Immunomodulation methods and compositions
EP1255770A4 (de) *	2000-02-03	2004-12-08	Merck & Co Inc	Analoge des melanin konzentrierenden hormons
US7220720B2 (en) *	2000-02-03	2007-05-22	Merk & Co., Inc.	Melanin-concentrating hormone analogs
US20070135425A1 (en) *	2001-05-04	2007-06-14	Amgen Inc.	Fused heterocyclic compounds
US6809104B2 (en) *	2001-05-04	2004-10-26	Tularik Inc.	Fused heterocyclic compounds
GB0112343D0 (en) *	2001-05-21	2001-07-11	Norske Stats Oljeselskap	Well treatment
EP1485405A4 (de) *	2001-05-31	2005-09-21	Merck & Co Inc	Melanin konzentrierende hormonanaloge
JP2004537581A (ja) *	2001-08-08	2004-12-16	メルク　エンド　カムパニー　インコーポレーテッド	メラニン濃縮ホルモン拮抗物質
WO2003060091A2 (en) *	2002-01-09	2003-07-24	Merck & Co., Inc.	Selective melanin-concentrating hormone type -1 receptor agonists
KR20030066187A (ko) *	2002-02-05	2003-08-09	나드리화장품주식회사	미백 화장료 조성물
PL376659A1 (pl) *	2002-11-06	2006-01-09	Tularik Inc.	Skondensowane związki heterocykliczne
NO347192B1 (no)	2004-06-17	2023-06-26	Equinor Energy As	Brønnbehandling
CA2569770C (en) *	2004-06-17	2012-02-21	Statoil Asa	Water reductions in subterranean formations
MX2007013262A (es) *	2005-04-26	2008-01-21	Statoil Asa	Metodo de construccion y tratamiento de pozos.
KR100839194B1 (ko)	2006-12-14	2008-06-17	부경대학교 산학협력단	양식 넙치의 멜라닌농축호르몬
GB2450502B (en) *	2007-06-26	2012-03-07	Statoil Asa	Microbial enhanced oil recovery
WO2009043523A2 (en) *	2007-09-11	2009-04-09	Mondobiotech Laboratories Ag	Cortistatin 17 and neuropeptide 1 for use as therapeutic agent
US20100184679A1 (en) *	2007-09-11	2010-07-22	Dorian Bevec	Use of a combination of cart peptides as a therapeutic agent

1989
- 1989-03-22 US US07/326,984 patent/US5049655A/en not_active Expired - Lifetime
1990
- 1990-03-20 DK DK90905279.7T patent/DK0464105T3/da active
- 1990-03-20 JP JP2505271A patent/JP2944202B2/ja not_active Expired - Lifetime
- 1990-03-20 AT AT90905279T patent/ATE141288T1/de active
- 1990-03-20 WO PCT/US1990/001492 patent/WO1990011295A1/en active IP Right Grant
- 1990-03-20 CA CA002046900A patent/CA2046900C/en not_active Expired - Lifetime
- 1990-03-20 EP EP90905279A patent/EP0464105B1/de not_active Expired - Lifetime
- 1990-03-20 DE DE69028101T patent/DE69028101T2/de not_active Expired - Fee Related
1994
- 1994-03-09 US US08/208,531 patent/US5449766A/en not_active Expired - Lifetime
1995
- 1995-05-23 US US08/447,613 patent/US5530095A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CA2046900A1 (en)	1990-09-23
EP0464105B1 (de)	1996-08-14
DE69028101T2 (de)	1997-03-06
CA2046900C (en)	2000-08-22
EP0464105A4 (en)	1992-08-12
JP2944202B2 (ja)	1999-08-30
DK0464105T3 (da)	1997-01-06
US5449766A (en)	1995-09-12
US5530095A (en)	1996-06-25
ATE141288T1 (de)	1996-08-15
JPH04503812A (ja)	1992-07-09
US5049655A (en)	1991-09-17
WO1990011295A1 (en)	1990-10-04
EP0464105A1 (de)	1992-01-08

Publication	Publication Date	Title
DE69028101D1 (de)	1996-09-19	Melaninkonzentrierende hormone und dns die diese expremieren
KR100345254B1 (ko)	2003-08-02	생물학적샘플속의인터루킨12또는인터루킨12의p40아단위를검출하는방법
Prinz et al.	1994	T cell clones from psoriasis skin lesions can promote keratinocyte proliferation in vitro via secreted products
US7052684B2 (en)	2006-05-30	Methods of healing wounds and fibrotic disorders using IL-10
Goldstein et al.	2004	Thymosins: chemistry and biological properties in health and disease
DE69132275T2 (de)	2001-01-25	Beta-type ähnlicher transformierender wachstumfaktor
DE69032816T2 (de)	1999-07-29	Verwendung von oncostatin m zur suppression von mhc antigenen
Lernhardt et al.	1982	T-cell hybridomas which produce B lymphocyte replication factors only
JP2010155859A (ja)	2010-07-15	生物活性ケラチンタンパク質
DE69332413D1 (de)	2002-11-21	Interleukin-2 analoge mit niedriger toxizität zur verwendung in der immuntherapie
JPH075481B2 (ja)	1995-01-25	創傷の治癒
MX7701E (es)	1990-09-20	Procedimiento para preparar peptidos
KR100424553B1 (ko)	2004-07-01	사람인터루킨-6억제제
ES545760A0 (es)	1986-07-16	Procedimiento para preparar peptidos liberadores de la hormona del crecimiento.
ES2173856T3 (es)	2002-11-01	Proceso para la preparacion de vectores geneticos para la expresion del factor de crecimiento nervioso en celulas eucariotas.
Bhartiya et al.	1992	Enhanced wound healing in animal models by interferon and an interferon inducer
JPS63122699A (ja)	1988-05-26	ペプチド
TAKAOKA et al.	1993	Purification and characterization of a bone-inducing protein from a murine osteosarcoma (Dunn type)
CA2566776C (en)	2011-08-02	Method for ameliorating an inflammatory skin condition
Quaroni et al.	1980	Biochemical characterization of collagens synthesized by intestinal epithelial cell cultures.
JP3160013B2 (ja)	2001-04-23	新規ペプチド
Vaughan et al.	1996	DNA encoding NEI and NGE peptides
Dimaline et al.	1987	A novel family of VIP-like peptides from the dogfish scyliorhinus canicula.
HUT66624A (en)	1994-12-28	Novel cytokine
WO2024122722A1 (ko)	2024-06-13	연골 재생용 펩타이드 및 이의 용도

Legal Events

Date	Code	Title	Description
1997-09-11	8364	No opposition during term of opposition
2010-01-21	8339	Ceased/non-payment of the annual fee