DE69033072D1 - Verfahren und Mittel zum Nachweis von Krankheitszuständen aus Änderungen im Östrogenstoffwechsel - Google Patents
Verfahren und Mittel zum Nachweis von Krankheitszuständen aus Änderungen im ÖstrogenstoffwechselInfo
- Publication number
- DE69033072D1 DE69033072D1 DE69033072T DE69033072T DE69033072D1 DE 69033072 D1 DE69033072 D1 DE 69033072D1 DE 69033072 T DE69033072 T DE 69033072T DE 69033072 T DE69033072 T DE 69033072T DE 69033072 D1 DE69033072 D1 DE 69033072D1
- Authority
- DE
- Germany
- Prior art keywords
- estrone
- metabolites
- enzymatic
- quotient
- estrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229940011871 estrogen Drugs 0.000 title abstract 4
- 239000000262 estrogen Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- 230000004060 metabolic process Effects 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- DNXHEGUUPJUMQT-UHFFFAOYSA-N (+)-estrone Natural products OC1=CC=C2C3CCC(C)(C(CC4)=O)C4C3CCC2=C1 DNXHEGUUPJUMQT-UHFFFAOYSA-N 0.000 abstract 4
- DNXHEGUUPJUMQT-CBZIJGRNSA-N Estrone Chemical compound OC1=CC=C2[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1 DNXHEGUUPJUMQT-CBZIJGRNSA-N 0.000 abstract 4
- 230000002255 enzymatic effect Effects 0.000 abstract 4
- 229960003399 estrone Drugs 0.000 abstract 4
- 239000002207 metabolite Substances 0.000 abstract 4
- 241000124008 Mammalia Species 0.000 abstract 3
- 230000007170 pathology Effects 0.000 abstract 3
- 238000012360 testing method Methods 0.000 abstract 3
- 230000004075 alteration Effects 0.000 abstract 2
- 238000003149 assay kit Methods 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 150000002167 estrones Chemical class 0.000 abstract 1
- 230000033444 hydroxylation Effects 0.000 abstract 1
- 238000005805 hydroxylation reaction Methods 0.000 abstract 1
- 238000011835 investigation Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
- 230000011987 methylation Effects 0.000 abstract 1
- 238000007069 methylation reaction Methods 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/743—Steroid hormones
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38106489A | 1989-07-17 | 1989-07-17 | |
| US54929090A | 1990-07-11 | 1990-07-11 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69033072D1 true DE69033072D1 (de) | 1999-06-02 |
| DE69033072T2 DE69033072T2 (de) | 1999-10-28 |
Family
ID=27009231
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69033072T Expired - Lifetime DE69033072T2 (de) | 1989-07-17 | 1990-07-17 | Verfahren und Mittel zum Nachweis von Krankheitszuständen aus Änderungen im Östrogenstoffwechsel |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0409176B1 (de) |
| JP (1) | JPH03215745A (de) |
| AT (1) | ATE179522T1 (de) |
| AU (1) | AU641409B2 (de) |
| CA (1) | CA2021309C (de) |
| DE (1) | DE69033072T2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5854009A (en) * | 1995-09-19 | 1998-12-29 | Immuna Care Corporation | Method of detecting estrogen-sensitive pathologies |
| US5962242A (en) * | 1995-09-19 | 1999-10-05 | Immuna Care Corporation | Methods of predicting estrogen-dependent osteopenia |
| CN113189334B (zh) * | 2021-04-27 | 2022-04-26 | 华南农业大学 | Comt蛋白在食蟹猴超数排卵良好应答预测中的应用 |
| PL441360A1 (pl) * | 2022-06-02 | 2023-12-04 | Gdański Uniwersytet Medyczny | Zastosowanie nadtlenku wodoru oraz 17β-estradiolu i jego metabolitów jako biomarkerów w sposobie diagnozowania in vitro chorób neurodegeneracyjnych |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4366241A (en) * | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| US4711856A (en) * | 1984-09-19 | 1987-12-08 | Mayo Medical Resources | Nuclear binding assay for steroid receptor functionality in cancerous cells |
| EP0200960A1 (de) * | 1985-05-08 | 1986-11-12 | Abbott Laboratories | Fluoreszenzpolarisationsimmunoassay auf Gesamtöstriol |
-
1990
- 1990-07-17 AU AU59051/90A patent/AU641409B2/en not_active Expired
- 1990-07-17 AT AT90113694T patent/ATE179522T1/de not_active IP Right Cessation
- 1990-07-17 CA CA002021309A patent/CA2021309C/en not_active Expired - Lifetime
- 1990-07-17 DE DE69033072T patent/DE69033072T2/de not_active Expired - Lifetime
- 1990-07-17 JP JP2190349A patent/JPH03215745A/ja active Pending
- 1990-07-17 EP EP90113694A patent/EP0409176B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH03215745A (ja) | 1991-09-20 |
| DE69033072T2 (de) | 1999-10-28 |
| ATE179522T1 (de) | 1999-05-15 |
| AU5905190A (en) | 1991-01-17 |
| CA2021309A1 (en) | 1991-01-18 |
| EP0409176B1 (de) | 1999-04-28 |
| CA2021309C (en) | 2003-04-01 |
| EP0409176A2 (de) | 1991-01-23 |
| EP0409176A3 (en) | 1991-10-30 |
| AU641409B2 (en) | 1993-09-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |