DE69133552D1 - Nicht-A, nicht-B Hepatitis Virus Antigen, und diagnostische Verfahren. - Google Patents

Nicht-A, nicht-B Hepatitis Virus Antigen, und diagnostische Verfahren.

Info

Publication number: DE69133552D1
Authority: DE; Germany
Prior art keywords: sequence; nanbv; hutch; hcv; strain
Prior art date: 1990-08-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69133552T

Other languages

English (en)

Other versions

DE69133552T2 (de

DE69133552C5 (de

Inventor

Suzanne Zebedee

Genevieve Inchauspe

Marc S Nasoff

Alfred M Prince

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bioprocess Pty Ltd

F Hoffmann La Roche AG

Original Assignee

Bioprocess Pty Ltd

New York Blood Center Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-25

Filing date

1991-08-23

Publication date

2007-01-04

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27416160&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69133552(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1991-08-23 Application filed by Bioprocess Pty Ltd, New York Blood Center Inc filed Critical Bioprocess Pty Ltd

2007-01-04 Application granted granted Critical

2007-01-04 Publication of DE69133552D1 publication Critical patent/DE69133552D1/de

2007-08-23 Publication of DE69133552T2 publication Critical patent/DE69133552T2/de

2008-01-10 Publication of DE69133552C5 publication Critical patent/DE69133552C5/de

2011-08-24 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/23—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a GST-tag
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/82—Hepatitis associated antigens and antibodies
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/826—Viruses

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Virology (AREA)
Immunology (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Communicable Diseases (AREA)
Microbiology (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Gastroenterology & Hepatology (AREA)
Hematology (AREA)
Cell Biology (AREA)
Epidemiology (AREA)
Food Science & Technology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Mycology (AREA)
Pharmacology & Pharmacy (AREA)
Biotechnology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DE69133552T 1990-08-25 1991-08-23 Nicht-A, nicht-B Hepatitis Virus Antigen, und diagnostische Verfahren. Expired - Lifetime DE69133552C5 (de)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date
US57364390A	1990-08-25	1990-08-25
US573643		1990-08-27
US61636990A	1990-11-21	1990-11-21
US616369		1990-11-21
US74856491A	1991-08-21	1991-08-21
US748564		1991-08-21

Publications (3)

Publication Number	Publication Date
DE69133552D1 true DE69133552D1 (de)	2007-01-04
DE69133552T2 DE69133552T2 (de)	2007-08-23
DE69133552C5 DE69133552C5 (de)	2008-01-10

Family

ID=27416160

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69133552T Expired - Lifetime DE69133552C5 (de)	1990-08-25	1991-08-23	Nicht-A, nicht-B Hepatitis Virus Antigen, und diagnostische Verfahren.

Country Status (9)

Country	Link
EP (2)	EP0544838A4 (de)
KR (1)	KR930702365A (de)
AT (1)	ATE346302T1 (de)
AU (1)	AU673135B2 (de)
CA (1)	CA2090335A1 (de)
DE (1)	DE69133552C5 (de)
DK (1)	DK1227323T4 (de)
ES (1)	ES2273934T5 (de)
WO (1)	WO1992003458A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE144993T1 (de) *	1990-12-14	1996-11-15	Innogenetics Nv	Synthetische antigene zum nachweis von antikörpern gegen hepatitis c-virus
CA2111108A1 (en) *	1991-06-10	1992-12-23	Joong Myung Cho	Hepatitis c diagnostics and vaccines
JP3516681B2 (ja)	1991-06-24	2004-04-05	カイロンコーポレイション	Ｃ型肝炎ウイルス（ｈｃｖ）ポリペプチド
ATE161291T1 (de) *	1991-08-27	1998-01-15	Hoffmann La Roche	Verfahren und reagenzien zum nachweis von hepatitis c
US6667387B1 (en)	1996-09-30	2003-12-23	N.V. Innogenetics S.A.	HCV core peptides
US6709828B1 (en)	1992-03-06	2004-03-23	N.V. Innogenetics S.A.	Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them
DE4240980A1 (de) *	1992-08-07	1994-02-10	Boehringer Mannheim Gmbh	HCV Peptidantigene und Verfahren zur Bestimmung von HCV
US6153378A (en) *	1992-10-16	2000-11-28	Bionova Corporation	Diagnosis of, and vaccination against, a positive stranded RNA virus using an isolated, unprocessed polypeptide encoded by a substantially complete genome of such virus
WO1994021816A1 (en) *	1993-03-25	1994-09-29	Envirocon International Incorporated	Test kits and methods for rapidly testing for contamination by microorganisms
GB9507232D0 (en) *	1995-04-07	1995-05-31	Gatsby Charitable Foundation	Plant pathogen resistance genes and uses thereof
CN1061991C (zh) *	1994-06-08	2001-02-14	北京医科大学	新型血吸虫疫苗肽(三)
CN1061990C (zh) *	1994-06-08	2001-02-14	北京医科大学	新型血吸虫疫苗肽(一)
CN1068334C (zh) *	1994-06-08	2001-07-11	北京医科大学	新型血吸虫疫苗肽(二)
WO2001051500A1 (en)	2000-01-14	2001-07-19	The United States Of America, Represented By The Secretary, Department Of Health And Human Services	Oligodeoxynucleotide and its use to induce an immune response
WO2004011650A2 (en)	2002-07-24	2004-02-05	Intercell Ag	Antigens encoded by alternative reading frame from pathogenic viruses
AU2003258672B2 (en)	2002-09-13	2008-10-30	Intercell Ag	Method for isolating hepatitis C virus peptides
WO2004084938A1 (en)	2003-03-24	2004-10-07	Intercell Ag	Improved vaccines
CN1822856B (zh)	2003-07-11	2010-04-28	英特塞尔股份公司	Hcv疫苗

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3744242A1 (de) *	1987-02-20	1989-07-06	Seelig Renate	Virusantigen, verfahren zu seiner gewinnung und anwendung in diagnose und therapie (impfstoff)
US5032511A (en) *	1987-03-31	1991-07-16	Mitsubishi Kasei Corporation	DNA fragments coding for antigens specific to non-A non-B hepatitis, expression vectors containing said DNA fragments, transformants and process for producing said antigens
CA1341629C (en) *	1987-11-18	2012-05-08	Chiron Corporation	Hepatitis c diagnostics and vaccines
AU624105B2 (en) *	1987-11-18	1992-06-04	Novartis Vaccines And Diagnostics, Inc.	Nanbv diagnostics and vaccines
EP0423239A4 (en) *	1988-07-06	1992-05-20	Genelabs Incorporated	Post-transfusion, non-a, non-b hepatitis virus and antigens
IL91371A0 (en) *	1988-08-24	1990-04-29	Us Commerce	Clones or vectors bearing dna sequences of non-a and non-b hepatitis and a method for detecting these materials in blood
US5191064A (en) *	1988-09-30	1993-03-02	The Research Foundation For Microbial Diseases (Osaka University)	Non-a, non-b hepatitis virus antigen peptide
JPH02167081A (ja) *	1988-12-21	1990-06-27	Tetsuo Nakamura	非Ａ非Ｂ型肝炎ウイルスゲノムＲＮＡ、ｃＤＮＡおよびウイルス抗原蛋白質
UA50829C2 (uk) *	1989-03-17	2002-11-15	Чірон Корпорейшн	Очищений поліпептид, що містить антиген вірусу гепатиту с, полінуклеотид, вектор, клітини, система експресії, моноклональне антитіло, препарат поліклональних антитіл, нуклеотидна проба, аналітичні набори, спосіб виявлення нуклеїнових кислот, способи імуноаналізу, вакцина, спосіб одержання антитіл

1991
- 1991-08-23 CA CA002090335A patent/CA2090335A1/en not_active Abandoned
- 1991-08-23 ES ES02006640T patent/ES2273934T5/es not_active Expired - Lifetime
- 1991-08-23 AU AU89041/91A patent/AU673135B2/en not_active Ceased
- 1991-08-23 DE DE69133552T patent/DE69133552C5/de not_active Expired - Lifetime
- 1991-08-23 KR KR1019930700552A patent/KR930702365A/ko not_active Ceased
- 1991-08-23 EP EP91920080A patent/EP0544838A4/en not_active Withdrawn
- 1991-08-23 DK DK02006640.3T patent/DK1227323T4/da active
- 1991-08-23 EP EP02006640A patent/EP1227323B2/de not_active Expired - Lifetime
- 1991-08-23 WO PCT/US1991/006037 patent/WO1992003458A1/en not_active Application Discontinuation
- 1991-08-23 AT AT02006640T patent/ATE346302T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
ES2273934T3 (es)	2007-05-16
EP0544838A4 (en)	1997-09-10
DE69133552T2 (de)	2007-08-23
EP1227323A1 (de)	2002-07-31
AU673135B2 (en)	1996-10-31
EP1227323B1 (de)	2006-11-22
EP0544838A1 (de)	1993-06-09
CA2090335A1 (en)	1992-02-26
AU8904191A (en)	1992-03-17
DE69133552C5 (de)	2008-01-10
DK1227323T3 (da)	2007-03-26
DK1227323T4 (da)	2011-04-26
KR930702365A (ko)	1993-09-08
WO1992003458A1 (en)	1992-03-05
EP1227323B2 (de)	2011-01-19
ATE346302T1 (de)	2006-12-15
ES2273934T5 (es)	2011-05-17

Publication	Publication Date	Title
DE69133552D1 (de)	2007-01-04	Nicht-A, nicht-B Hepatitis Virus Antigen, und diagnostische Verfahren.
EP0992581B1 (de)	2004-08-25	Von menschlichen T-Zellen immunodominante Epitopen des Virus der C-Hepatitis
Battegay et al.	1995	Patients with chronic hepatitis C have circulating cytotoxic T cells which recognize hepatitis C virus-encoded peptides binding to HLA-A2. 1 molecules
Nishizawa et al.	1997	A novel DNA virus (TTV) associated with elevated transaminase levels in posttransfusion hepatitis of unknown etiology
ATE195953T1 (de)	2000-09-15	Peptide zur induktion von immunantwort durch zytotoxischen t lymphocyten gegen das virus von hepatitis c
Martell et al.	1994	Dynamic behavior of hepatitis C virus quasispecies in patients undergoing orthotopic liver transplantation
MY110260A (en)	1998-03-31	Nanbv diagnostics and vaccines.
HK38293A (en)	1993-04-30	Hepatitis c virus
Kurokohchi et al.	1996	Use of recombinant protein to identify a motif-negative human cytotoxic T-cell epitope presented by HLA-A2 in the hepatitis C virus NS3 region
DE68903165D1 (de)	1992-11-12	Rns des genoms des non-a, non-b-hepatitisvirus und antigenisches virales protein.
Matsuura et al.	1993	The molecular biology of hepatitis C virus
EP0644894A1 (de)	1995-03-29	Peptid für die stimulierung von für hepatitis c virus spesifischen cytotoischen t lymphozyten.
Höhne et al.	1994	Sequence variability in the env-coding region of hepatitis C virus isolated from patients infected during a single source outbreak
Okamoto et al.	1992	Full-length nucleotide sequence of a Japanese hepatitis C virus isolate (HC-J1) with high homology to USA isolates
Honda et al.	1992	Sequence comparisons for a hepatitis C virus genome RNA isolated from a patient with liver cirrhosis
DE69106141D1 (de)	1995-02-02	Non-a non-b sequenzen.
Major et al.	2000	Characterization of hepatitis C virus infectious clones in chimpanzees: long-term studies
KR950000880A (ko)	1995-01-03	한국형 씨(c)형 간염 바이러스의 일종인 케이에이치씨브이-엘2(khcv-l2)의 전체 뉴클레오티드서열 및 이로부터 유추된 아미노산 서열
Mishiro et al.	1994	Diversity of the classification and nomenclature systems for hepatitis C virus genotypes: a proposed solution to the present confusion
MY105097A (en)	1994-08-30	Nanbv diagnostics and vaccines
NO950527L (no)	1990-04-02	Analogifremgangsmåte ved fremstilling av non-A, non-B hepatittvirus-antigenpeptid

Legal Events

Date	Code	Title	Description
2007-05-10	8363	Opposition against the patent
2007-06-28	8327	Change in the person/name/address of the patent owner	Owner name: BIOPROCESS PTY. LTD., EVELEIGH, NORTH SOUTH WA, AU Owner name: F. HOFFMANN-LA ROCHE LTD., BASEL, CH
2007-11-08	8315	Request for restriction filed
2007-11-15	8318	Patent restricted
2008-01-10	8393	Patent changed during the limitation procedure (changed patent specification reprinted)
2011-03-24	8366	Restricted maintained after opposition proceedings