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DE69300674T2 - Verfahren zur isolierung von lactoferrin und lactoperoxidase aus milch und milchprodukten. - Google Patents

Verfahren zur isolierung von lactoferrin und lactoperoxidase aus milch und milchprodukten.

Info

Publication number
DE69300674T2
DE69300674T2 DE69300674T DE69300674T DE69300674T2 DE 69300674 T2 DE69300674 T2 DE 69300674T2 DE 69300674 T DE69300674 T DE 69300674T DE 69300674 T DE69300674 T DE 69300674T DE 69300674 T2 DE69300674 T2 DE 69300674T2
Authority
DE
Germany
Prior art keywords
milk
column
proteins
whey
bed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69300674T
Other languages
German (de)
English (en)
Other versions
DE69300674D1 (de
Inventor
Marinus Kivits
Klaas Kussendrager
Albert Verver
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Campina Melkune BV
Original Assignee
Campina Melkune BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19860296&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69300674(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Campina Melkune BV filed Critical Campina Melkune BV
Application granted granted Critical
Publication of DE69300674D1 publication Critical patent/DE69300674D1/de
Publication of DE69300674T2 publication Critical patent/DE69300674T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
    • A23C9/146—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by ion-exchange
    • A23C9/1465—Chromatographic separation of protein or lactose fraction; Adsorption of protein or lactose fraction followed by elution
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
    • A23J1/205—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey from whey, e.g. lactalbumine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/832—Milk; colostrum
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/833—Whey; cheese

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Dairy Products (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • General Preparation And Processing Of Foods (AREA)
DE69300674T 1992-01-15 1993-01-14 Verfahren zur isolierung von lactoferrin und lactoperoxidase aus milch und milchprodukten. Expired - Fee Related DE69300674T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL9200064 1992-01-15
PCT/NL1993/000014 WO1993013676A1 (fr) 1992-01-15 1993-01-14 Procede d'isolation de lactoferrine et de lactoperoxydase a partir du lait et des produits laitiers, et produits ainsi obtenus

Publications (2)

Publication Number Publication Date
DE69300674D1 DE69300674D1 (de) 1995-11-23
DE69300674T2 true DE69300674T2 (de) 1996-05-15

Family

ID=19860296

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69300674T Expired - Fee Related DE69300674T2 (de) 1992-01-15 1993-01-14 Verfahren zur isolierung von lactoferrin und lactoperoxidase aus milch und milchprodukten.

Country Status (10)

Country Link
US (1) US5596082A (fr)
EP (1) EP0620709B1 (fr)
AT (1) ATE129125T1 (fr)
CA (1) CA2128111C (fr)
DE (1) DE69300674T2 (fr)
DK (1) DK0620709T3 (fr)
ES (1) ES2089797T3 (fr)
FI (1) FI111326B (fr)
NZ (1) NZ249235A (fr)
WO (1) WO1993013676A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10062056A1 (de) * 2000-12-15 2002-07-04 Henkel Ecolab Gmbh & Co Ohg Verfahren zur Reinigung von Ionenaustauscher-Kunststoffharzen

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69524386D1 (de) * 1994-02-16 2002-01-17 Pharming Intellectual Pty Bv Isolierung von lactoferrin aus milch
ES2089970B1 (es) * 1994-03-08 1997-05-01 Univ Zaragoza Metodo de aislamiento de lactoferrina y otras proteinas lacteas.
JP3112637B2 (ja) * 1994-09-30 2000-11-27 雪印乳業株式会社 骨強化剤
JP2974604B2 (ja) * 1996-01-23 1999-11-10 雪印乳業株式会社 塩基性タンパク質組成物、塩基性ペプチド組成物及びその利用
JP3073439B2 (ja) * 1996-02-08 2000-08-07 雪印乳業株式会社 骨形成促進及び骨吸収防止剤
NL1005677C2 (nl) * 1997-03-27 1998-09-29 Campina Melkunie Bv Werkwijze voor het winnen van groeifactoren, of een samenstelling die één of meer groeifactoren bevat, uit melk of een derivaat daarvan.
ATE290323T1 (de) * 2001-06-01 2005-03-15 Upfront Chromatography As Fraktionierung von proteinhaltigen mischungen
NZ535784A (en) * 2002-03-07 2006-02-24 Upfront Chromatography As A process of isolating lactoferrin
US20030191193A1 (en) * 2002-04-03 2003-10-09 Jillian Cornish Lactoferrin
FR2841747B1 (fr) 2002-07-02 2004-08-20 Cie Laitiere Europeenne Isolat de proteines de lait et procede pour sa preparation
WO2004082397A1 (fr) * 2003-03-21 2004-09-30 Upfront Chromatography A/S Procede pour volumes a haut rendement servant au fractionnement de biomolecules par des systemes chromatographiques
JP4263932B2 (ja) * 2003-04-01 2009-05-13 雪印乳業株式会社 ラクトフェリンの製造方法
US20040259770A1 (en) * 2003-06-19 2004-12-23 Rush University Medical Center Method for determining leukocyte activation
DK1717311T3 (da) * 2004-02-17 2013-01-14 Morinaga Milk Industry Co Ltd Fremgangsmåde til fremstilling af lactoperoxidase
US7125963B2 (en) * 2004-03-03 2006-10-24 En N Tech Inc Treatments for contaminant reduction in lactoferrin preparations and lactoferrin containing compositions
US8551547B2 (en) * 2006-11-10 2013-10-08 Murray Goulburn Co-Operative Co., Limited Process for the preparation of angiogenin
US7919589B2 (en) 2007-07-10 2011-04-05 Glanbia Nutritionals (Ireland), Ltd. Method for removing endotoxin from proteins
KR101760758B1 (ko) 2008-05-14 2017-07-24 애그리컬쳐 빅토리아 서비스 피티와이 엘티디 질병 및 장애를 치료하기 위한 안지오게닌 또는 안지오게닌 아고니스트의 이용
AU2013204740C1 (en) 2012-05-10 2015-10-01 Agriculture Victoria Services Pty Ltd Methods of treating cancer using angiogenin or an angiogenin agonist
AU2013204858B2 (en) * 2012-10-08 2015-06-25 Saputo Dairy Australia Pty Limited Improved process for purifying milk proteins and products thereof
US9661868B2 (en) 2013-07-16 2017-05-30 Mead Johnson Nutrition Company Expanded bed adsorption methods for isolation of basic milk proteins including lactoferrin
CZ2013885A3 (cs) 2013-11-15 2015-08-19 Univerzita PalackĂ©ho Způsob separace syrovátkových proteinů z mléčného média a zařízení k provádění tohoto způsobu
DK3097787T3 (en) * 2015-05-24 2019-03-11 Dmk Deutsches Milchkontor Gmbh PROCEDURE FOR OBTAINING LACTOPEROXIDASE FROM MILK
EP3097788B1 (fr) * 2015-05-26 2018-10-17 DMK Deutsches Milchkontor GmbH Procédé pour obtenir lactoferrin à partir du lait
US20210388058A1 (en) 2018-11-06 2021-12-16 Arhel Projektiranje In Inzeniring D.O.O. Method for manufacturing highly purified lactoferrin and lactoperoxidase from milk, colostrum and acid or sweet whey
AU2020203454B1 (en) * 2020-05-26 2021-07-22 HPS Tech Pty Ltd Processing protein
FR3117736B1 (fr) * 2020-12-22 2024-04-05 Savencia Nouveau procédé de préparation d’un isolat de protéines cationiques de lactosérum et le produit ainsi obtenu

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2505615A1 (fr) * 1981-05-15 1982-11-19 Elf Aquitaine Procede d'extraction de lactoferrine et d'immunoglobulines du lait
BE901672A (fr) * 1985-02-07 1985-08-07 Oleofina Sa Procede de purification de proteines du lait et de ses derives.
IE61701B1 (en) * 1986-07-17 1994-11-30 Morinaga Milk Industry Co Ltd Process for producing bovine lactoferrin in high purity
FR2613368B1 (fr) * 1987-03-10 1989-06-23 Entremont Sa Procede pour extraire des proteines du lactoserum, par adsorption et elution
SE458818B (sv) * 1987-11-27 1989-05-16 Svenska Mejeriernas Riksforeni Foerfarande foer utvinning av rena fraktioner av laktoperoxidas och laktoferrin ur mjoelkserum
NZ230031A (en) * 1988-07-27 1991-10-25 Snow Brand Milk Products Co Ltd Separation of proteins (e.g. lactoferrin) using affinity gel carrier in a rotary column
JP2686831B2 (ja) * 1989-09-22 1997-12-08 雪印乳業株式会社 鉄結合性蛋白質を分離、精製し、採取する方法
JP2974434B2 (ja) * 1990-03-15 1999-11-10 雪印乳業株式会社 分泌性コンポネント含有組成物
JPH05202098A (ja) * 1992-01-29 1993-08-10 Snow Brand Milk Prod Co Ltd 乳質原料から生理活性物質の製造法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10062056A1 (de) * 2000-12-15 2002-07-04 Henkel Ecolab Gmbh & Co Ohg Verfahren zur Reinigung von Ionenaustauscher-Kunststoffharzen

Also Published As

Publication number Publication date
FI943368A0 (fi) 1994-07-15
CA2128111A1 (fr) 1993-07-22
NZ249235A (en) 1995-12-21
ATE129125T1 (de) 1995-11-15
FI111326B (fi) 2003-07-15
EP0620709B1 (fr) 1995-10-18
FI943368A7 (fi) 1994-07-15
US5596082A (en) 1997-01-21
EP0620709A1 (fr) 1994-10-26
DE69300674D1 (de) 1995-11-23
ES2089797T3 (es) 1996-10-01
DK0620709T3 (da) 1995-12-04
CA2128111C (fr) 1998-06-16
WO1993013676A1 (fr) 1993-07-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee