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DE69332087D1 - Verfahren zur erhöhung den stickoxidkonzentration im blut - Google Patents

Verfahren zur erhöhung den stickoxidkonzentration im blut

Info

Publication number
DE69332087D1
DE69332087D1 DE69332087T DE69332087T DE69332087D1 DE 69332087 D1 DE69332087 D1 DE 69332087D1 DE 69332087 T DE69332087 T DE 69332087T DE 69332087 T DE69332087 T DE 69332087T DE 69332087 D1 DE69332087 D1 DE 69332087D1
Authority
DE
Germany
Prior art keywords
blood
increasing
oxide concentration
nitrogen oxide
nitric oxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69332087T
Other languages
English (en)
Other versions
DE69332087T2 (de
Inventor
Inc Etobicocke Vasogen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vasogen Ireland Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of DE69332087D1 publication Critical patent/DE69332087D1/de
Application granted granted Critical
Publication of DE69332087T2 publication Critical patent/DE69332087T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0023—Aggression treatment or altering
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/32—Oxygenators without membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0216—Ozone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0266—Nitrogen (N)
    • A61M2202/0275—Nitric oxide [NO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/05—General characteristics of the apparatus combined with other kinds of therapy
    • A61M2205/051—General characteristics of the apparatus combined with other kinds of therapy with radiation therapy
    • A61M2205/053—General characteristics of the apparatus combined with other kinds of therapy with radiation therapy ultraviolet

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
DE69332087T 1992-02-07 1993-02-08 Verfahren zur erhöhung den stickoxidkonzentration im blut Expired - Fee Related DE69332087T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83279892A 1992-02-07 1992-02-07
US94132692A 1992-09-04 1992-09-04
PCT/GB1993/000259 WO1993015779A1 (en) 1992-02-07 1993-02-08 Method of increasing the concentration of nitric oxide in blood

Publications (2)

Publication Number Publication Date
DE69332087D1 true DE69332087D1 (de) 2002-08-08
DE69332087T2 DE69332087T2 (de) 2002-10-24

Family

ID=27125561

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69332087T Expired - Fee Related DE69332087T2 (de) 1992-02-07 1993-02-08 Verfahren zur erhöhung den stickoxidkonzentration im blut
DE69334101T Expired - Fee Related DE69334101T2 (de) 1992-02-07 1993-02-08 Verwendung von Blut mit erhöhter Stickoxidkonzentration zur Herstellung eines Medikaments

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69334101T Expired - Fee Related DE69334101T2 (de) 1992-02-07 1993-02-08 Verwendung von Blut mit erhöhter Stickoxidkonzentration zur Herstellung eines Medikaments

Country Status (13)

Country Link
US (1) US5834030A (de)
EP (2) EP1243278B1 (de)
JP (1) JP3989949B2 (de)
AT (2) ATE219953T1 (de)
AU (1) AU681999B2 (de)
CA (1) CA2129630C (de)
DE (2) DE69332087T2 (de)
DK (2) DK0680346T3 (de)
ES (2) ES2280454T3 (de)
HK (1) HK1053068B (de)
NZ (1) NZ249176A (de)
PT (2) PT680346E (de)
WO (1) WO1993015779A1 (de)

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US5980954A (en) 1992-02-07 1999-11-09 Vasogen Ireland Limited Treatment of autoimmune diseases
US6669965B2 (en) 1992-02-07 2003-12-30 Vasogen Ireland Limited Method of treating atherosclerosis
US6204058B1 (en) 1992-02-07 2001-03-20 Vasogen Ireland Limited Treatment of autoimmune diseases
US5910316A (en) * 1992-08-24 1999-06-08 The United States Of America, As Represented By The Department Of Health And Human Services Use of nitric oxide-releasing agents to treat impotency
AU760465B2 (en) * 1995-05-05 2003-05-15 Vasogen Ireland Limited Endothelial lining effects and treatment of vasospastic disorders
CA2194485C (en) * 1995-05-05 2001-09-18 Anthony Ernest Bolton Endothelial lining effects and treatment of vasospastic disorders
US6866755B2 (en) * 2001-08-01 2005-03-15 Battelle Memorial Institute Photolytic artificial lung
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PT1011696E (pt) * 1997-09-12 2004-03-31 Vasogen Ireland Ltd Tratamento do stresse e precondicoes contra o stresse
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US7045124B1 (en) * 1999-01-12 2006-05-16 Vasogen Irelend Limited Pre-conditioning against cell death
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CA2309424A1 (en) 2000-05-25 2001-11-25 Vasogen Ireland Limited Apoptotic entities for use in treatment of neurodegenerative and other neurological disorders
CN1267212C (zh) 2000-08-11 2006-08-02 大卫·R·怀特洛克 氨氧化细菌在药物中的应用、由其制成的制剂及用其处理过的用品
NL1015999C2 (nl) * 2000-08-23 2002-02-26 A J Van Liebergen Holding B V Inrichting voor het verwarmen van bloed of andere fysiologische vloeistoffen.
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US7335383B2 (en) * 2001-01-16 2008-02-26 The Regents Of The University Of Michigan Generation of nitric oxide in vivo from nitrite, nitrate or nitrosothiols endogenous in blood
US7128904B2 (en) * 2001-01-16 2006-10-31 The Regents Of The University Of Michigan Material containing metal ion ligand complex producing nitric oxide in contact with blood
US7122208B2 (en) 2001-04-06 2006-10-17 Vasogen Ireland Limited Compositions containing apoptotic entities
JP4286661B2 (ja) * 2001-08-01 2009-07-01 ブルース エフ． モンジック， 生理学的ガス交換を与えるための光分解セル
US6472390B1 (en) * 2001-11-13 2002-10-29 Duke University Use of therapeutic dosages for nitric oxide donors which do not significantly lower blood pressure or pulmonary artery pressure
BR0306868A (pt) * 2002-01-11 2005-04-12 David R Whitlock Composições incluindo bactérias oxidando amonìaco e métodos para usar as mesmas
CA2377442A1 (en) * 2002-03-20 2003-09-20 Thomas Ichim Increasing tumor oxygen content by administration of stressed cells
US20050244298A1 (en) * 2002-04-10 2005-11-03 Smith Eldon R Electrocardiographic aspects of chf treatment
US7531133B2 (en) 2002-09-10 2009-05-12 Pulmonox Technologies Corporation Use of nitric oxide gas in an extracorporeal circuitry to treat blood plasma
US20050189302A1 (en) * 2003-07-31 2005-09-01 Latino Joseph S. Viral inactivation using ozone
US20100318014A1 (en) * 2003-07-31 2010-12-16 Latino Joseph S Treatment of acute ischemic brain stroke with ozone
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US20050087498A1 (en) * 2003-07-31 2005-04-28 Keyser Steven A. Ozone delivery system including gas-fluid contacting devices and methods of use
US20100316730A1 (en) * 2003-07-31 2010-12-16 Latino Joseph S Treatment of cardiovascular diseases with ozone
US7736494B2 (en) * 2003-07-31 2010-06-15 Acquisci, Inc. Ozone delivery system including a variable pitch gas-fluid contact device
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CN100475275C (zh) * 2004-01-05 2009-04-08 董永华 肿瘤血管栓塞剂及其储存和释放装置
CN1950120B (zh) 2004-05-11 2010-10-20 伟亚医疗森迪斯公司 一氧化氮气体的间歇计量
US8518457B2 (en) 2004-05-11 2013-08-27 Pulmonox Technologies Corporation Use of inhaled gaseous nitric oxide as a mucolytic agent or expectorant
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US20080181832A1 (en) * 2007-01-30 2008-07-31 Lih-Ren Shiue Pocket-size ozone generator
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ITMI20131667A1 (it) * 2013-10-09 2015-04-10 Ind Paolo Gobbi Frattini Metodo per pre-trattare le cellule ematiche prima della separazione.
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Also Published As

Publication number Publication date
ATE219953T1 (de) 2002-07-15
AU3506393A (en) 1993-09-03
EP0680346B1 (de) 2002-07-03
DE69334101T2 (de) 2007-10-04
DE69334101D1 (de) 2007-02-15
EP1243278B1 (de) 2007-01-03
CA2129630C (en) 2003-09-23
EP1243278A3 (de) 2003-02-26
NZ249176A (en) 1996-11-26
HK1053068B (en) 2007-03-30
DE69332087T2 (de) 2002-10-24
WO1993015779A1 (en) 1993-08-19
EP1243278A2 (de) 2002-09-25
EP0680346A1 (de) 1995-11-08
US5834030A (en) 1998-11-10
ATE350046T1 (de) 2007-01-15
JPH07503722A (ja) 1995-04-20
CA2129630A1 (en) 1993-08-08
ES2179828T3 (es) 2003-02-01
HK1053068A1 (en) 2003-10-10
ES2280454T3 (es) 2007-09-16
AU681999B2 (en) 1997-09-18
DK0680346T3 (da) 2002-10-28
JP3989949B2 (ja) 2007-10-10
DK1243278T3 (da) 2007-05-07
PT1243278E (pt) 2007-04-30
PT680346E (pt) 2002-10-31

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: VASOGEN IRELAND LTD., SHANNON, COUNTY CLARE, IE

8381 Inventor (new situation)

Inventor name: BOLTON, ANTHONY E., SHEFFIELD S7 1NB, GB

Inventor name: BOLTON, ANTHONY E., SHEFFELD, GB

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee