DK0631502T3 - Lymfocytaktivitetsregulering ved hjælp af HLA-peptider - Google Patents
Lymfocytaktivitetsregulering ved hjælp af HLA-peptiderInfo
- Publication number
- DK0631502T3 DK0631502T3 DK93918763T DK93918763T DK0631502T3 DK 0631502 T3 DK0631502 T3 DK 0631502T3 DK 93918763 T DK93918763 T DK 93918763T DK 93918763 T DK93918763 T DK 93918763T DK 0631502 T3 DK0631502 T3 DK 0631502T3
- Authority
- DK
- Denmark
- Prior art keywords
- peptides
- lymphocyte activity
- activity regulation
- hla peptides
- domains
- Prior art date
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 230000000694 effects Effects 0.000 title abstract 2
- 210000004698 lymphocyte Anatomy 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 102000011786 HLA-A Antigens Human genes 0.000 abstract 1
- 108010075704 HLA-A Antigens Proteins 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000009089 cytolysis Effects 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/6425—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56977—HLA or MHC typing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/844,716 US5888512A (en) | 1987-01-30 | 1992-03-02 | Lymphocyte activity regulation by HLA peptides |
| PCT/US1993/001758 WO1993017699A1 (en) | 1992-03-02 | 1993-02-25 | Lymphocyte activity regulation by hla peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0631502T3 true DK0631502T3 (da) | 2001-01-02 |
Family
ID=25293452
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93918763T DK0631502T3 (da) | 1992-03-02 | 1993-02-25 | Lymfocytaktivitetsregulering ved hjælp af HLA-peptider |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5888512A (da) |
| EP (1) | EP0631502B1 (da) |
| JP (1) | JP2846470B2 (da) |
| AT (1) | ATE196150T1 (da) |
| AU (1) | AU678381B2 (da) |
| CA (1) | CA2131299A1 (da) |
| DE (1) | DE69329379T2 (da) |
| DK (1) | DK0631502T3 (da) |
| ES (1) | ES2150949T3 (da) |
| GR (1) | GR3034964T3 (da) |
| PT (1) | PT631502E (da) |
| WO (1) | WO1993017699A1 (da) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5723128A (en) * | 1987-01-30 | 1998-03-03 | The Board Of Trustees Of The Leland Stanford Junior University | Cytotoxic T-cell lymphocyte ("CTL") activity regulation by class I MHC peptides |
| US7011834B1 (en) | 1987-01-30 | 2006-03-14 | The Board Of Trustees Of Leland Stanford Junior University | Immunomodulating dimers |
| US5639458A (en) * | 1987-03-20 | 1997-06-17 | Regents Of The University Of California | Class I MHC modulation of surface receptor activity |
| US5843156A (en) * | 1988-08-24 | 1998-12-01 | Endoluminal Therapeutics, Inc. | Local polymeric gel cellular therapy |
| JPH09508617A (ja) * | 1993-11-10 | 1997-09-02 | ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ | 表面膜タンパク質および免疫応答に対するそれらの影響 |
| US5977300A (en) * | 1994-06-03 | 1999-11-02 | Ludwig Institute Of Cancer Research | Isolated nonapeptide which bind to HLA-B44 molecules and the uses thereof |
| CA2210812C (en) * | 1995-01-16 | 2009-09-01 | Nicholas Manolios | T-cell affecting peptides |
| US6162434A (en) | 1995-05-03 | 2000-12-19 | Sangstat Medical Corporation | Cytomodulating peptide for inhibiting lymphocyte activity |
| US5753625A (en) * | 1995-05-12 | 1998-05-19 | Sangstat Medical Corporation | Treatment for inhibiting the progression of autoimmune disease |
| AU1823697A (en) * | 1996-01-02 | 1997-07-28 | Board Of Trustees Of The Leland Stanford Junior University | Interaction of hla proteins with members of the hsp70 family of proteins |
| US6436903B1 (en) | 1996-05-22 | 2002-08-20 | Stanford University (Board Of Trustees Of The Leland Standford Junior University) | Immunomodulating compounds comprising d-isomers of amino acids |
| EP0950065B1 (de) * | 1996-09-18 | 2003-02-19 | Gerhild Wildner | Peptide als diagnostikum und therapeutikum für autoimmunerkrankungen |
| EP1027073A2 (en) * | 1996-11-19 | 2000-08-16 | Sangstat Medical Corporation | Enhanced effects for hapten conjugated therapeutics |
| PL336302A1 (en) * | 1997-04-11 | 2000-06-19 | Sangstat Medical Corp | Cytomodulating lypophylic peptides useful in moudulating the immune system and inhibiting inflammations |
| US6696545B1 (en) | 1997-04-11 | 2004-02-24 | Sangstat Medical Corporation | Cytomodulating lipophilic peptides for modulating immune system activity and inhibiting inflammation |
| CN1441676B (zh) | 2000-03-31 | 2012-08-22 | 普渡研究基金会 | 用配体-免疫原缀合物治疗的方法 |
| US7094413B2 (en) | 2002-01-24 | 2006-08-22 | Sangstat Medical Corporation | Combined therapy for treatment of HIV infection |
| US20110104186A1 (en) | 2004-06-24 | 2011-05-05 | Nicholas Valiante | Small molecule immunopotentiators and assays for their detection |
| EP1982992B1 (en) | 2006-02-07 | 2010-10-27 | NEC Corporation | Hla-binding peptide, precursor thereof, dna fragment encoding the same and recombinant vector |
| TW200745163A (en) * | 2006-02-17 | 2007-12-16 | Syntonix Pharmaceuticals Inc | Peptides that block the binding of IgG to FcRn |
| GB0609121D0 (en) | 2006-05-09 | 2006-06-21 | Univ Birmingham | Peptide Therapy |
| JPWO2008044567A1 (ja) | 2006-10-12 | 2010-02-12 | 日本電気株式会社 | Hla結合性ペプチド、その前駆体、それをコードするdna断片および組み換えベクター |
| ES2425486T3 (es) * | 2007-05-09 | 2013-10-15 | Circassia Limited | Análisis de pronóstico para determinar la respuesta de células T a antígenos HLA y uso del mismo en el campo del trasplante de tejidos |
| MX2010001363A (es) * | 2007-08-09 | 2010-03-09 | Syntonix Pharmaceuticals Inc | Peptidos inmunomoduladores. |
| US20100048488A1 (en) * | 2008-08-01 | 2010-02-25 | Syntonix Pharmaceuticals, Inc. | Immunomodulatory peptides |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL69686A (en) * | 1983-09-11 | 1988-03-31 | Yeda Res & Dev | Compositions containing cell membrane proteins and process for their preparation |
| US5202424A (en) * | 1984-03-19 | 1993-04-13 | The Rockefeller University | Mesangial cell-derived receptors for advanced glycosylation endproducts and uses thereof |
| US4681760A (en) * | 1985-04-17 | 1987-07-21 | The Board Of Trustees Of The Leland Stanford Junior University | Method of conferring immunotolerance to a specific antigen |
| WO1988005784A1 (en) * | 1987-01-30 | 1988-08-11 | The Board Of Trustees Of The Leland Stanford Junio | Lymphocyte inhibition by hla peptides |
| EP0400077A4 (en) * | 1988-02-12 | 1990-12-27 | The Regents Of The University Of California | Use of synthetic peptides to generate and manipulate cellular immunity |
| WO1990010016A1 (en) * | 1989-03-03 | 1990-09-07 | The Regents Of The University Of California | Class i mhc modulation of surface receptor activity |
| US5073540A (en) * | 1989-05-15 | 1991-12-17 | Receptron | Composite binding site drugs |
| CA2081582A1 (en) * | 1991-11-05 | 1993-05-06 | Teodorica Bugawan | Methods and reagents for hla class i dna typing |
-
1992
- 1992-03-02 US US07/844,716 patent/US5888512A/en not_active Expired - Fee Related
-
1993
- 1993-02-25 ES ES93918763T patent/ES2150949T3/es not_active Expired - Lifetime
- 1993-02-25 EP EP93918763A patent/EP0631502B1/en not_active Expired - Lifetime
- 1993-02-25 PT PT93918763T patent/PT631502E/pt unknown
- 1993-02-25 JP JP5515785A patent/JP2846470B2/ja not_active Expired - Fee Related
- 1993-02-25 AU AU48078/93A patent/AU678381B2/en not_active Ceased
- 1993-02-25 DK DK93918763T patent/DK0631502T3/da active
- 1993-02-25 DE DE69329379T patent/DE69329379T2/de not_active Expired - Fee Related
- 1993-02-25 AT AT93918763T patent/ATE196150T1/de not_active IP Right Cessation
- 1993-02-25 CA CA002131299A patent/CA2131299A1/en not_active Abandoned
- 1993-02-25 WO PCT/US1993/001758 patent/WO1993017699A1/en active IP Right Grant
-
2000
- 2000-11-30 GR GR20000402667T patent/GR3034964T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2131299A1 (en) | 1993-09-16 |
| AU4807893A (en) | 1993-10-05 |
| ES2150949T3 (es) | 2000-12-16 |
| JP2846470B2 (ja) | 1999-01-13 |
| WO1993017699A1 (en) | 1993-09-16 |
| EP0631502A1 (en) | 1995-01-04 |
| DE69329379D1 (de) | 2000-10-12 |
| JPH08504168A (ja) | 1996-05-07 |
| AU678381B2 (en) | 1997-05-29 |
| ATE196150T1 (de) | 2000-09-15 |
| EP0631502A4 (en) | 1996-07-24 |
| EP0631502B1 (en) | 2000-09-06 |
| DE69329379T2 (de) | 2001-03-29 |
| US5888512A (en) | 1999-03-30 |
| GR3034964T3 (en) | 2001-02-28 |
| PT631502E (pt) | 2001-03-30 |
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