DK0830130T3 - TNF-alfa-omdannende enzym - Google Patents
TNF-alfa-omdannende enzymInfo
- Publication number
- DK0830130T3 DK0830130T3 DK96923209T DK96923209T DK0830130T3 DK 0830130 T3 DK0830130 T3 DK 0830130T3 DK 96923209 T DK96923209 T DK 96923209T DK 96923209 T DK96923209 T DK 96923209T DK 0830130 T3 DK0830130 T3 DK 0830130T3
- Authority
- DK
- Denmark
- Prior art keywords
- converting enzyme
- tnf alpha
- protease
- alpha converting
- isolated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Pulmonology (AREA)
- AIDS & HIV (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Vascular Medicine (AREA)
- Biotechnology (AREA)
- Cardiology (AREA)
- Microbiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48245895A | 1995-06-08 | 1995-06-08 | |
| US50461495A | 1995-07-20 | 1995-07-20 | |
| US08/655,345 US5830742A (en) | 1995-06-08 | 1996-05-23 | TNF-α converting enzyme |
| PCT/US1996/008407 WO1996041624A1 (en) | 1995-06-08 | 1996-06-03 | TNF-α CONVERTING ENZYME |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0830130T3 true DK0830130T3 (da) | 2004-12-20 |
Family
ID=27413615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96923209T DK0830130T3 (da) | 1995-06-08 | 1996-06-03 | TNF-alfa-omdannende enzym |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0830130B9 (da) |
| JP (1) | JP4326022B2 (da) |
| AT (1) | ATE274346T1 (da) |
| AU (1) | AU712759C (da) |
| CA (1) | CA2222650C (da) |
| DE (1) | DE69633231T2 (da) |
| DK (1) | DK0830130T3 (da) |
| ES (1) | ES2227598T3 (da) |
| IL (1) | IL122305A0 (da) |
| NO (1) | NO323623B1 (da) |
| NZ (2) | NZ312285A (da) |
| PT (1) | PT830130E (da) |
| WO (1) | WO1996041624A1 (da) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6180403B1 (en) | 1999-10-28 | 2001-01-30 | Isis Pharmaceuticals Inc. | Antisense inhibition of tumor necrosis factor alpha converting enzyme (TACE) expression |
| US6255064B1 (en) | 1996-03-01 | 2001-07-03 | The Procter & Gamble Company | Disintegrin metalloprotease and its use |
| EP0900272A2 (en) * | 1996-03-26 | 1999-03-10 | Glaxo Group Limited | Tumor necrosis factor alpha convertase |
| US5853977A (en) * | 1996-07-12 | 1998-12-29 | Schering Corporation | Mammalian TNF-α convertases |
| JP2000500660A (ja) * | 1996-07-12 | 2000-01-25 | シェーリング コーポレイション | 哺乳動物ＴＮＦ―αコンベルターゼ |
| EP0988385A2 (en) | 1997-01-21 | 2000-03-29 | Human Genome Sciences | Tace-like and matrilysin-like polypeptides |
| CA2281085A1 (en) * | 1997-02-25 | 1998-08-27 | The Procter & Gamble Company | Use of a novel disintegrin metalloprotease, mutants, fragments and the like |
| US6551857B2 (en) | 1997-04-04 | 2003-04-22 | Elm Technology Corporation | Three dimensional structure integrated circuits |
| US6548633B1 (en) | 1998-12-22 | 2003-04-15 | Genset, S.A. | Complementary DNA's encoding proteins with signal peptides |
| DE69936445T2 (de) * | 1998-02-04 | 2008-04-10 | Immunex Corp., Seattle | Kristallines tnf-alpha-konvertierendes enzym und verwendung davon |
| US6842704B2 (en) | 1998-02-04 | 2005-01-11 | Immunex Corporation | Crystalline TNF-α-converting enzyme and uses thereof |
| US6632667B1 (en) | 1999-10-28 | 2003-10-14 | Isis Pharmaceuticals, Inc. | Modulation of L-selectin shedding via inhibition of tumor necrosis factor-α converting enzyme (TACE) |
| EP1449538A1 (en) | 2003-02-21 | 2004-08-25 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Inhibition of TACE or amphiregulin for the modulation of EGF receptor signal transactivation |
| WO2005030798A2 (en) | 2003-09-24 | 2005-04-07 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | TNFαCONVERTING ENZYME INHIBITORY AGENTS AND STIMULATORY AGENTS- |
| ES2755386T5 (es) * | 2006-08-28 | 2023-04-05 | Ares Trading Sa | Proceso para la purificación de proteínas que contienen fragmentos Fc |
| MX2009002013A (es) * | 2006-08-28 | 2009-03-09 | Ares Trading Sa | Proceso para la purificacion de proteinas de fusion fc. |
| WO2012104581A1 (en) | 2011-02-01 | 2012-08-09 | Cancer Research Technology Limited | Anti-tace antibody molecules and their uses |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE148992T1 (de) * | 1989-08-16 | 1997-03-15 | Chiron Corp | Zusammensetzungen zur hemmung der bildung von proteinhormon und deren verwendungen |
| WO1991002756A1 (en) * | 1989-08-16 | 1991-03-07 | Cetus Corporation | Prohormone cleavage site blocking antibody |
| JP3268777B2 (ja) * | 1990-06-22 | 2002-03-25 | ゲゼルシャフト・フュア・ビオテクノロギッシェ・フォルシュンク・ミット・ベシュレンクテル・ハフツング | セリンプロテアーゼをコードするｄｎａ―配列とその関連対象物 |
| AU8337291A (en) * | 1990-08-06 | 1992-03-02 | Cetus Corporation | Methods for the identification of cytokine convertase inhibitors |
| EP0648225A1 (en) * | 1992-06-25 | 1995-04-19 | Chiron Corporation | Compositions for the inhibition of protein hormone formation and uses thereof |
| EP0749494A1 (en) * | 1994-03-07 | 1996-12-27 | Chiron Corporation | Compositions for the inhibition of tnf formation and uses thereof |
| EP0900272A2 (en) * | 1996-03-26 | 1999-03-10 | Glaxo Group Limited | Tumor necrosis factor alpha convertase |
-
1996
- 1996-06-03 AU AU63781/96A patent/AU712759C/en not_active Ceased
- 1996-06-03 EP EP96923209A patent/EP0830130B9/en not_active Expired - Lifetime
- 1996-06-03 IL IL12230596A patent/IL122305A0/xx not_active IP Right Cessation
- 1996-06-03 WO PCT/US1996/008407 patent/WO1996041624A1/en active IP Right Grant
- 1996-06-03 DK DK96923209T patent/DK0830130T3/da active
- 1996-06-03 DE DE69633231T patent/DE69633231T2/de not_active Expired - Fee Related
- 1996-06-03 CA CA002222650A patent/CA2222650C/en not_active Expired - Fee Related
- 1996-06-03 PT PT96923209T patent/PT830130E/pt unknown
- 1996-06-03 NZ NZ312285A patent/NZ312285A/en not_active IP Right Cessation
- 1996-06-03 NZ NZ510390A patent/NZ510390A/xx not_active IP Right Cessation
- 1996-06-03 AT AT96923209T patent/ATE274346T1/de not_active IP Right Cessation
- 1996-06-03 ES ES96923209T patent/ES2227598T3/es not_active Expired - Lifetime
- 1996-06-03 JP JP50310797A patent/JP4326022B2/ja not_active Expired - Fee Related
-
1997
- 1997-11-26 NO NO19975438A patent/NO323623B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0830130A1 (en) | 1998-03-25 |
| IL122305A0 (en) | 1998-04-05 |
| WO1996041624A1 (en) | 1996-12-27 |
| CA2222650A1 (en) | 1996-12-27 |
| CA2222650C (en) | 2009-10-13 |
| EP0830130B9 (en) | 2004-12-29 |
| DE69633231T2 (de) | 2005-08-04 |
| JP2002515020A (ja) | 2002-05-21 |
| AU712759B2 (en) | 1999-11-18 |
| NO323623B1 (no) | 2007-06-18 |
| NO975438L (no) | 1998-02-06 |
| NO975438D0 (no) | 1997-11-26 |
| PT830130E (pt) | 2004-11-30 |
| AU712759C (en) | 2001-08-09 |
| ATE274346T1 (de) | 2004-09-15 |
| EP0830130B1 (en) | 2004-08-25 |
| MX9709744A (es) | 1998-07-31 |
| DE69633231D1 (de) | 2004-09-30 |
| NZ510390A (en) | 2002-11-26 |
| JP4326022B2 (ja) | 2009-09-02 |
| NZ312285A (en) | 2001-04-27 |
| EP0830130A4 (en) | 2000-03-29 |
| AU6378196A (en) | 1997-01-09 |
| ES2227598T3 (es) | 2005-04-01 |
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