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DK0934406T3 - Syntetiske promotor biblioteker til udvalgte organismer og promotorer fra sådanne biblioteker - Google Patents

Syntetiske promotor biblioteker til udvalgte organismer og promotorer fra sådanne biblioteker

Info

Publication number
DK0934406T3
DK0934406T3 DK97936613T DK97936613T DK0934406T3 DK 0934406 T3 DK0934406 T3 DK 0934406T3 DK 97936613 T DK97936613 T DK 97936613T DK 97936613 T DK97936613 T DK 97936613T DK 0934406 T3 DK0934406 T3 DK 0934406T3
Authority
DK
Denmark
Prior art keywords
libraries
promoters
synthetic promoter
selected organisms
organisms
Prior art date
Application number
DK97936613T
Other languages
English (en)
Inventor
Peter Ruhdal Jensen
Karin Hammer
Original Assignee
Peter Ruhdal Jensen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Peter Ruhdal Jensen filed Critical Peter Ruhdal Jensen
Application granted granted Critical
Publication of DK0934406T3 publication Critical patent/DK0934406T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1051—Gene trapping, e.g. exon-, intron-, IRES-, signal sequence-trap cloning, trap vectors

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK97936613T 1996-08-23 1997-08-25 Syntetiske promotor biblioteker til udvalgte organismer og promotorer fra sådanne biblioteker DK0934406T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK88696 1996-08-23
PCT/DK1997/000342 WO1998007846A1 (en) 1996-08-23 1997-08-25 Artificial promoter libraries for selected organisms and promoters derived from such libraries

Publications (1)

Publication Number Publication Date
DK0934406T3 true DK0934406T3 (da) 2009-01-26

Family

ID=8098645

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97936613T DK0934406T3 (da) 1996-08-23 1997-08-25 Syntetiske promotor biblioteker til udvalgte organismer og promotorer fra sådanne biblioteker

Country Status (8)

Country Link
US (1) US7199233B1 (da)
EP (2) EP0934406B1 (da)
JP (2) JP2001503249A (da)
CN (1) CN1243827C (da)
AU (1) AU3938397A (da)
DE (1) DE69739121D1 (da)
DK (1) DK0934406T3 (da)
WO (1) WO1998007846A1 (da)

Families Citing this family (47)

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AU8574898A (en) 1997-07-14 1999-02-08 Valentis, Inc. Method for the identification of synthetic cell- or tissue-specific transcriptional regulatory regions
US6475183B1 (en) 1998-06-03 2002-11-05 Baxter International Inc. Direct dual filling device for sealing agents
ES2335828T3 (es) 1998-09-25 2010-04-05 Ajinomoto Co., Inc. Bacterias corineformes para producir l-glu.
US6555674B2 (en) 2000-08-09 2003-04-29 Nsgene A/S JeT promoter
AU8847801A (en) 2000-08-25 2002-03-04 Basf Plant Science Gmbh Plant polynucleotides encoding novel prenyl proteases
WO2002101058A1 (fr) * 2001-06-06 2002-12-19 Takeda Chemical Industries, Ltd. Nouveau promoteur
EP1696035A3 (en) 2002-04-10 2008-04-02 Novozymes A/S Improved bacillus host cell
US7521204B2 (en) 2002-04-10 2009-04-21 Novozymes A/S Bacillus host cell
US6644365B1 (en) 2002-04-19 2003-11-11 Baxter International, Inc. Tilting direct dual filling device
CA2483338C (en) * 2002-04-22 2014-10-14 Genencor International, Inc. Method of creating a library of bacterial clones with varying levels of gene expression
AU2003225123A1 (en) * 2002-04-22 2003-11-03 E. I. Du Pont De Nemours And Company Promoter and plasmid system for genetic engineering
DK1576094T3 (da) * 2002-04-22 2012-01-02 Danisco Us Inc Fremgangsmåder til at danne modificerede promotere resulterende i varierende genekspressionsniveauer
US20080076678A1 (en) 2005-06-15 2008-03-27 Philippe Soucaille Method of creating a library of bacterial clones with varying levels of gene expression
WO2004033421A2 (en) 2002-10-04 2004-04-22 Genencor International, Inc. Improved production of bacterial strains
US20050079617A1 (en) 2003-10-03 2005-04-14 Cervin Marguerite A. Glucose transport mutants for production of biomaterial
EP1579005A4 (en) * 2002-11-15 2007-07-25 Sangamo Biosciences Inc METHOD AND COMPOSITIONS FOR THE ANALYSIS OF REGULATORY SEQUENCES
JP4821606B2 (ja) 2003-03-12 2011-11-24 味の素株式会社 効率的にＬ−グルタミン酸を生産するためのプロモーター変異による細菌のｓｕｃＡＢ発現の最適化
WO2006116400A2 (en) 2005-04-27 2006-11-02 Massachusetts Institute Of Technology Promoter engineering and genetic control
WO2007146975A2 (en) * 2006-06-13 2007-12-21 Athenix Corporation Methods for generating genetic diversity by permutational mutagenesis
WO2008027558A2 (en) 2006-08-31 2008-03-06 Codon Devices, Inc. Iterative nucleic acid assembly using activation of vector-encoded traits
NZ577310A (en) 2006-11-29 2011-09-30 Athenix Corp Improved grg23 epsp synthases: compositions and methods of use
US7618801B2 (en) 2007-10-30 2009-11-17 Danison US Inc. Streptomyces protease
KR101683302B1 (ko) 2008-03-28 2016-12-06 다니스코 유에스 인크. 박테리아 세포 내 로커스 증폭 방법
AR076941A1 (es) 2009-06-11 2011-07-20 Danisco Us Inc Cepa de bacillus para una mayor produccion de proteina
EP2311961A1 (en) * 2009-10-15 2011-04-20 DKFZ Deutsches Krebsforschungszentrum Model-guided random assembly PCR for the synthesis of eukaryotic promoters
US20120315670A1 (en) 2009-11-02 2012-12-13 Gen9, Inc. Compositions and Methods for the Regulation of Multiple Genes of Interest in a Cell
EP4039363A1 (en) 2010-11-12 2022-08-10 Gen9, Inc. Protein arrays and methods of using and making the same
AU2011338841B2 (en) 2010-11-12 2017-02-16 Gen9, Inc. Methods and devices for nucleic acids synthesis
CN102286517B (zh) * 2011-06-10 2016-08-03 中国科学院天津工业生物技术研究所 利用人工调控元件及其文库调控微生物染色体上基因表达强度的方法
EP3954770A1 (en) 2011-08-26 2022-02-16 Gen9, Inc. Compositions and methods for high fidelity assembly of nucleic acids
EP2573172A1 (en) 2011-09-21 2013-03-27 Heinrich-Heine-Universität Düsseldorf Means and methods for rhamnolipid production
US9150853B2 (en) 2012-03-21 2015-10-06 Gen9, Inc. Methods for screening proteins using DNA encoded chemical libraries as templates for enzyme catalysis
CA2871505C (en) 2012-04-24 2021-10-12 Gen9, Inc. Methods for sorting nucleic acids and multiplexed preparative in vitro cloning
CA2877823A1 (en) 2012-06-25 2014-01-03 Gen9, Inc. Methods for nucleic acid assembly and high throughput sequencing
WO2014159850A2 (en) 2013-03-14 2014-10-02 Codexis, Inc. Low-phosphate repressible promoter
BR112018000257A2 (pt) 2015-07-08 2018-09-04 Rheinisch Westfaelische Technische Hochschule Aachen Rwth célula hospedeira, método para produzir um haa, uso de uma célula hospedeira, método para produzir uma célula hospedeira, célula, preparação de haa, método para produzir uma composição de ácido graxo e composição de ácido graxo
CN105296486B (zh) * 2015-11-18 2019-04-26 湖北大学 一种启动子文库构建方法和强启动子
US9988624B2 (en) * 2015-12-07 2018-06-05 Zymergen Inc. Microbial strain improvement by a HTP genomic engineering platform
US11208649B2 (en) * 2015-12-07 2021-12-28 Zymergen Inc. HTP genomic engineering platform
CN105603537A (zh) * 2016-03-11 2016-05-25 南京工业大学 一种启动子文库的构建方法及其应用
WO2018226964A2 (en) * 2017-06-07 2018-12-13 Zymergen Inc. Promoters from corynebacterium glutamicum and uses thereof in regulating ancillary gene expression
CN108118059B (zh) * 2017-12-30 2021-03-19 苏州金唯智生物科技有限公司 一种改进的启动子及其组成的载体和应用
EP3546582A1 (en) * 2018-03-26 2019-10-02 KWS SAAT SE & Co. KGaA Promoter activating elements
CN110317807A (zh) * 2018-03-29 2019-10-11 中国科学院天津工业生物技术研究所 一种谷氨酸棒杆菌人工启动子文库
CA3117051A1 (en) 2018-11-05 2020-05-14 Genentech, Inc. Methods of producing two chain proteins in prokaryotic host cells
CN109486847B (zh) * 2018-12-17 2021-03-02 江南大学 基于人工串联启动子的枯草芽孢杆菌高效诱导表达系统
JP2023506254A (ja) * 2019-12-16 2023-02-15 ギンゴー バイオワークス， インコーポレイテッド ヒスチジン、プリン経路代謝生成物およびプラスミドｄｎａの産生増強

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9215550D0 (en) 1992-07-22 1992-09-02 Celltech Ltd Protein expression system
AU6776194A (en) * 1993-04-28 1994-11-21 Hybritech Incorporated Method for creating optimized regulatory regions affecting protein expression and protein trafficking

Also Published As

Publication number Publication date
JP4469005B2 (ja) 2010-05-26
JP2009022293A (ja) 2009-02-05
EP0934406A2 (en) 1999-08-11
CN1233287A (zh) 1999-10-27
DE69739121D1 (de) 2009-01-02
JP2001503249A (ja) 2001-03-13
EP2034021A1 (en) 2009-03-11
EP0934406B1 (en) 2008-11-19
US7199233B1 (en) 2007-04-03
CN1243827C (zh) 2006-03-01
WO1998007846A1 (en) 1998-02-26
AU3938397A (en) 1998-03-06

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