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DK1042319T3 - Dihydrobenzofuraner - Google Patents

Dihydrobenzofuraner

Info

Publication number
DK1042319T3
DK1042319T3 DK98966288T DK98966288T DK1042319T3 DK 1042319 T3 DK1042319 T3 DK 1042319T3 DK 98966288 T DK98966288 T DK 98966288T DK 98966288 T DK98966288 T DK 98966288T DK 1042319 T3 DK1042319 T3 DK 1042319T3
Authority
DK
Denmark
Prior art keywords
dihydrobenzofuranes
meaningand
heterocycle
meanings
compounds
Prior art date
Application number
DK98966288T
Other languages
Danish (da)
English (en)
Inventor
Hildegard Boss
Hendrik Timmerman
Der Laan Ivonne Johanna Van
Wolf-Ruediger Ulrich
Ulrich Thibaut
Armin Hatzelmann
Dietrich Haefner
Rolf Beume
Hans-Peter Kley
Geert Jan Sterk
Der Mey Margaretha Van
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of DK1042319T3 publication Critical patent/DK1042319T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
DK98966288T 1997-12-15 1998-12-10 Dihydrobenzofuraner DK1042319T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97122039 1997-12-15
PCT/EP1998/008054 WO1999031090A1 (fr) 1997-12-15 1998-12-10 Dihydrobenzofurans

Publications (1)

Publication Number Publication Date
DK1042319T3 true DK1042319T3 (da) 2004-06-01

Family

ID=8227798

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98966288T DK1042319T3 (da) 1997-12-15 1998-12-10 Dihydrobenzofuraner

Country Status (17)

Country Link
US (1) US6380196B1 (fr)
EP (1) EP1042319B1 (fr)
JP (1) JP2002508368A (fr)
AT (1) ATE258930T1 (fr)
AU (1) AU753576B2 (fr)
CA (1) CA2314111A1 (fr)
CZ (1) CZ299304B6 (fr)
DE (1) DE69821530T2 (fr)
DK (1) DK1042319T3 (fr)
EE (1) EE04312B1 (fr)
ES (1) ES2216349T3 (fr)
HU (1) HU225114B1 (fr)
IL (1) IL136359A (fr)
PL (1) PL191236B1 (fr)
PT (1) PT1042319E (fr)
SI (1) SI1042319T1 (fr)
WO (1) WO1999031090A1 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200909479T2 (tr) 1999-08-21 2012-02-21 Nycomed Gmbh Sinerjistik kombinasyon.
AU7654200A (en) * 1999-09-14 2001-04-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Phthalazinone derivatives as pd3/4 inhibitors
EA005856B1 (ru) * 1999-10-25 2005-06-30 Алтана Фарма Аг Тетрагидротиопиранфталазиноновые производные в качестве ингибиторов pde4
EP1228046B1 (fr) * 1999-10-25 2007-09-26 Nycomed GmbH Derives de phthalazinone, utilises comme inhibiteurs de pde4
CZ20023997A3 (cs) * 2000-06-05 2003-05-14 Altana Pharma Ag Pyridazinonové deriváty
CA2438520C (fr) * 2001-02-15 2011-10-04 Altana Pharma Ag Derives de phtalazinone-piperidine en tant qu'inhibiteurs de pde4
JP4021329B2 (ja) * 2001-04-25 2007-12-12 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング ピペラジノ誘導体およびｐｄｅ４阻害剤としてのその使用
AU2002317733B2 (en) 2001-04-25 2007-12-13 Altana Pharma Ag Phthalazinones derivatives useful as PDE4/7 inhibitors
JP2005521711A (ja) * 2002-03-29 2005-07-21 中外製薬株式会社 呼吸器疾病の予防または治療のための医薬組成物
CA2494634A1 (fr) 2002-08-10 2004-03-04 Altana Pharma Ag Piperidine-pyridazones et phthalazones en tant qu'inhibiteurs de pde4
HRP20050197A2 (en) * 2002-08-10 2006-06-30 Altana Pharma Ag Piperidine-n-oxide-derivatives
AU2003255376A1 (en) * 2002-08-10 2004-03-11 Altana Pharma Ag Piperidine-derivatives as pde4 inhibitors
WO2004018451A1 (fr) * 2002-08-10 2004-03-04 Altana Pharma Ag Derives de pyridazinone utilises comme inhibiteurs de pde4
CA2517487A1 (fr) 2003-04-01 2004-10-14 Applied Research Systems Ars Holding N.V. Inhibiteurs de phosphodiesterases dans l'infecondite
US20080227790A1 (en) * 2004-02-04 2008-09-18 Altana Pharma Ag Pyridazinone Derivatives and their Use as Pde4 Inhibitors
WO2005075456A1 (fr) * 2004-02-04 2005-08-18 Altana Pharma Ag Derives de 2-(piperidin-4-yl)-4,5-dihydro-2h-pyridazin-3-one inhibiteurs de pde4
JP4890439B2 (ja) * 2005-03-07 2012-03-07 杏林製薬株式会社 ピラゾロピリジン−４−イルピリダジノン誘導体とその付加塩及びそれらを有効成分とするｐｄｅ阻害剤
AR057986A1 (es) * 2005-11-21 2008-01-09 Japan Tobacco Inc Compuesto heterociclico y su uso farmaceutico
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4721784A (en) * 1986-12-22 1988-01-26 Ortho Pharmaceutical Corporation 6-benzoxazinyl-2,3,4,5-tetrahydropyridazin-3-ones
DE59009351D1 (de) * 1989-04-17 1995-08-03 Byk Gulden Lomberg Chem Fab Neue arylpyridazine, ihre herstellung, verwendung und sie enthaltende arzneimittel.
JP3120857B2 (ja) 1990-02-19 2000-12-25 中外製薬株式会社 新規な縮合複素環化合物とこれを用いた抗喘息剤
JPH06501941A (ja) * 1990-10-16 1994-03-03 ビイク　グルデン　ロンベルク　ヒエーミツシエ　フアブリーク　ゲゼルシヤフト　ミツト　ベシユレンクテル　ハフツング アリールピリダジノン
AU1574892A (en) * 1991-04-26 1992-12-21 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel pyridazines
ATE141791T1 (de) * 1991-07-05 1996-09-15 Byk Gulden Lomberg Chem Fab Verwendung substituierter pyridazine gegen dermatosen
NZ244660A (en) 1991-10-09 1995-05-26 Syntex Inc Pyridopyridazine derivatives and medicaments
DE4230755A1 (de) * 1992-09-14 1994-03-17 Schering Ag Verwendung von PDE-Inhibitoren bei der Behandlung von Nieren- und Ureter-Erkrankungen
CZ141795A3 (en) 1992-12-02 1995-11-15 Pfizer 4-substituted catechol diethers as such and for treating diseases and pharmaceutical preparations based thereon
US5411935A (en) * 1993-03-17 1995-05-02 Sumitomo Chemical Co., Ltd. Dihydrobenzofuran derivatives, their production and use
PL185683B1 (pl) * 1994-07-22 2003-07-31 Altana Pharma Ag Dihydrobenzofurany
EP0722936B1 (fr) * 1994-08-09 2004-05-19 Eisai Co., Ltd. Compose de pyridazine condense
DE19533975A1 (de) * 1995-09-14 1997-03-20 Merck Patent Gmbh Arylalkyl-diazinone
US5821250A (en) * 1996-02-01 1998-10-13 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents

Also Published As

Publication number Publication date
ATE258930T1 (de) 2004-02-15
HU225114B1 (en) 2006-06-28
PT1042319E (pt) 2004-06-30
EE200000335A (et) 2001-10-15
EP1042319A1 (fr) 2000-10-11
IL136359A0 (en) 2001-06-14
PL341239A1 (en) 2001-03-26
EE04312B1 (et) 2004-06-15
EP1042319B1 (fr) 2004-02-04
IL136359A (en) 2003-03-12
US6380196B1 (en) 2002-04-30
CZ299304B6 (cs) 2008-06-11
DE69821530T2 (de) 2004-12-23
WO1999031090A1 (fr) 1999-06-24
CZ20002218A3 (cs) 2000-11-15
HUP0004561A2 (hu) 2002-03-28
AU753576B2 (en) 2002-10-24
PL191236B1 (pl) 2006-04-28
AU2270199A (en) 1999-07-05
DE69821530D1 (de) 2004-03-11
SI1042319T1 (en) 2004-08-31
HUP0004561A3 (en) 2002-04-29
CA2314111A1 (fr) 1999-06-24
ES2216349T3 (es) 2004-10-16
JP2002508368A (ja) 2002-03-19

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