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DK1734368T3 - Annexin-autoantistoffer anvendt som markörer for lungecancer - Google Patents

Annexin-autoantistoffer anvendt som markörer for lungecancer

Info

Publication number
DK1734368T3
DK1734368T3 DK06075982T DK06075982T DK1734368T3 DK 1734368 T3 DK1734368 T3 DK 1734368T3 DK 06075982 T DK06075982 T DK 06075982T DK 06075982 T DK06075982 T DK 06075982T DK 1734368 T3 DK1734368 T3 DK 1734368T3
Authority
DK
Denmark
Prior art keywords
markers
lung cancer
annexin
annexin autoantibodies
autoantibodies used
Prior art date
Application number
DK06075982T
Other languages
English (en)
Inventor
Samir M Hanash
David Misek
Robert Hinderer
David Beer
Franck Brichory
Original Assignee
Univ Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Michigan filed Critical Univ Michigan
Application granted granted Critical
Publication of DK1734368T3 publication Critical patent/DK1734368T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57423—Specifically defined cancers of lung
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4718—Lipocortins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK06075982T 1999-08-06 2000-08-04 Annexin-autoantistoffer anvendt som markörer for lungecancer DK1734368T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/370,337 US6645465B2 (en) 1999-08-06 1999-08-06 Annexin proteins and autoantibodies as serum markers for cancer
PCT/US2000/021514 WO2001011372A1 (en) 1999-08-06 2000-08-04 Annexins and autoantibodies used as markers for cancer

Publications (1)

Publication Number Publication Date
DK1734368T3 true DK1734368T3 (da) 2009-06-02

Family

ID=23459219

Family Applications (2)

Application Number Title Priority Date Filing Date
DK00952594T DK1200832T3 (da) 1999-08-06 2000-08-04 Annexiner og autoantistoffer anvendt som markörer for lungecancer og ösofageal cancer
DK06075982T DK1734368T3 (da) 1999-08-06 2000-08-04 Annexin-autoantistoffer anvendt som markörer for lungecancer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK00952594T DK1200832T3 (da) 1999-08-06 2000-08-04 Annexiner og autoantistoffer anvendt som markörer for lungecancer og ösofageal cancer

Country Status (10)

Country Link
US (5) US6645465B2 (da)
EP (3) EP1734368B1 (da)
JP (1) JP4594575B2 (da)
AT (3) ATE426167T1 (da)
AU (1) AU780772B2 (da)
CA (1) CA2380398C (da)
DE (2) DE60041839D1 (da)
DK (2) DK1200832T3 (da)
ES (2) ES2320585T3 (da)
WO (1) WO2001011372A1 (da)

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GB9827228D0 (en) * 1998-12-10 1999-02-03 Univ Nottingham Cancer detection method and reagents
US6645465B2 (en) * 1999-08-06 2003-11-11 Michigan, University Of The Regents Annexin proteins and autoantibodies as serum markers for cancer
US20030232399A1 (en) * 2000-06-14 2003-12-18 Robertson John Forsyth Russell Cancer detection methods and reagents
ATE426611T1 (de) * 2000-07-21 2009-04-15 Chemo Sero Therapeut Res Inst Verfahren zur reinigung eines kalziumionen- bindenden proteins
JP2004528025A (ja) 2001-02-21 2004-09-16 サーロメッド・インコーポレーテッド 修飾されたアネキシン蛋白質及び血栓症を防ぐための方法
US7635680B2 (en) 2001-02-21 2009-12-22 Alavita Pharmaceuticals, Inc. Attenuation of reperfusion injury
US7645739B2 (en) 2001-02-21 2010-01-12 Alavita Pharmaceuticals, Inc. Modified annexin compositions and methods of using same
US7635676B2 (en) 2001-02-21 2009-12-22 Alavita Pharmaccuticals, Inc. Modified annexin proteins and methods for their use in organ transplantation
US7214498B2 (en) * 2001-03-23 2007-05-08 Benaroya Research Institute At Virginia Mason Tumor associated antigens and methods of using the same
WO2003025568A2 (de) * 2001-09-14 2003-03-27 Reinhard Zeidler Identifizierung von antigenen durch xenogene, allogene oder autologe antikörper-vermittelte präzipitation
WO2003064593A2 (en) * 2001-11-09 2003-08-07 Virginia Mason Research Center Antigen panels and methods of using the same
GB2424273B (en) * 2002-11-14 2007-06-27 Univ Nottingham Method for preparing tumour marker protein
WO2004079368A2 (en) 2003-03-08 2004-09-16 Auvation Ltd Markers for colorectal cancer
EP1720611B1 (de) * 2004-02-16 2010-05-19 ProteoSys AG Diagnostische marker für krebs
WO2005114192A1 (en) * 2004-05-13 2005-12-01 Centre National De La Recherche Scientifique A device for binding a target entity to a bait entity and detection methods using the same
EP1778874B1 (en) 2004-07-30 2011-11-23 Adeza Biomedical Corporation Oncofetal fibronectin as a marker for cervical cancer
RU2277242C2 (ru) * 2004-08-23 2006-05-27 Александр Владимирович Балюра Способ диагностики опухолей
WO2006098144A1 (ja) * 2005-03-17 2006-09-21 National University Corporation Chiba University 特発性肺線維症の検出マーカー、検出キット及び検出方法
EP1724585A1 (en) * 2005-05-21 2006-11-22 ProteoSys AG Annexin for cancer risk assessment
EP1724586A3 (en) * 2005-05-21 2007-07-04 ProteoSys AG Annexin for cancer risk assessment
GB2426581A (en) * 2005-05-27 2006-11-29 Univ Nottingham Immunoassay methods
BRPI0610267B8 (pt) 2005-05-27 2021-07-27 Oncimmune Ltd métodos de detecção de um estado doentio ou de uma suscetibilidade à doença em um indivíduo mamífero, e, uso do método
US20060286074A1 (en) * 2005-05-31 2006-12-21 Yucheng Tang Methods for immunotherapy of cancer
US8999727B2 (en) * 2005-09-26 2015-04-07 Ulrich Loos Innovative TSH-R-Ab-kit
US20090197285A1 (en) * 2005-11-10 2009-08-06 University Of Kentucky Lung Cancer Diagnostic Assay
US9347945B2 (en) * 2005-12-22 2016-05-24 Abbott Molecular Inc. Methods and marker combinations for screening for predisposition to lung cancer
KR20090034961A (ko) * 2006-07-08 2009-04-08 유니버시티 오브 켄터키 리서치 파운데이션 폐암 진단 검사
US8574848B2 (en) * 2006-09-13 2013-11-05 Oncimmune Ltd. Immunoassay methods
US20080305512A1 (en) * 2006-10-26 2008-12-11 Mattingly Phillip G Assay for cardiac troponin autoantibodies
US7776605B2 (en) * 2006-10-26 2010-08-17 Abbott Laboratories Assay for cardiac troponin autoantibodies
EP2097750A2 (en) * 2006-10-26 2009-09-09 Abbott Laboratories Immunoassay of analytes in samples containing endogenous anti-analyte antibodies
US20090047689A1 (en) * 2007-06-20 2009-02-19 John Kolman Autoantigen biomarkers for early diagnosis of lung adenocarcinoma
GB0725239D0 (en) * 2007-12-24 2008-02-06 Oncimmune Ltd Calibrator for autoantibody assay
CN102171569A (zh) * 2008-05-09 2011-08-31 杜克大学 检测和治疗癌症的自身抗体
US9581599B2 (en) 2010-06-28 2017-02-28 The Board Of Regents Of The University Of Texas System Diagnosis of benign and cancerous growths by measuring circulating tumor stem cells and serum AnnexinA2
WO2012048190A1 (en) * 2010-10-08 2012-04-12 Regents Of The University Of Minnesota Annexin ii compositions and methods
KR20150010882A (ko) * 2013-07-19 2015-01-29 삼성전자주식회사 아넥신 Ａ2 결합단백질, ｐ53 단백질 및 ｐ18 단백질을 포함하는 융합 단백질 및 이를 포함하는 암의 예방 또는 치료용 조성물
EP3047277B1 (en) * 2013-09-18 2018-11-21 Adelaide Research & Innovation Pty Ltd. Autoantibody biomarkers of ovarian cancer
CA2930567C (en) 2013-11-13 2023-09-26 Regents Of The University Of Minnesota Annexin ii variant compositions and methods
CN104407151B (zh) * 2014-11-19 2016-06-08 汕头大学医学院 Kindlin-2，Myosin-9和Annexin II三蛋白联合预测食管鳞癌患者预后试剂盒
CN113721021B (zh) * 2021-09-16 2023-07-07 郑州大学 Prkcz自身抗体在食管鳞癌辅助诊断中的应用
CN116539885B (zh) * 2023-07-06 2023-09-29 上海秤信生物科技有限公司 用于乳腺癌早期检测的肿瘤自身抗原/抗体组合及应用

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JPH02496A (ja) * 1987-12-24 1990-01-05 Nippon Shinyaku Co Ltd モノクローナル抗体、製法、及び利用法
DE4012341A1 (de) * 1990-04-18 1991-10-24 Behringwerke Ag Monoklonale antikoerper gegen pp4, verfahren zu ihrer herstellung und ihre verwendung
DE4040306A1 (de) 1990-12-17 1992-06-25 Behringwerke Ag Verfahren zur bestimmung von antikoerpern gegen lipocortine
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JPH0772149A (ja) * 1993-06-30 1995-03-17 Nippon Shinyaku Co Ltd 肝癌又は肝硬変の診断薬及び診断法
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EP0651253A1 (en) * 1993-11-02 1995-05-03 Abbott Laboratories Immunoassay for the detection of human autoantibodies
US5658877A (en) * 1995-05-18 1997-08-19 Wisconsin Alumni Research Foundation Method to treat endotoxin effects by administration of 33 kilodalton phospholipid binding protein
ATE266203T1 (de) 1997-06-26 2004-05-15 Univ Michigan Methode zur identifizierung von tumorantigenen mit autoantikörpern in serum
JP4431798B2 (ja) * 1997-10-08 2010-03-17 昇 金子 尿中のアネキシンｖの分析方法及びその利用
CA2356963A1 (en) 1998-12-28 2000-07-06 David Hung Devices, methods and systems for collecting material from a breast duct
US6645465B2 (en) * 1999-08-06 2003-11-11 Michigan, University Of The Regents Annexin proteins and autoantibodies as serum markers for cancer

Also Published As

Publication number Publication date
US7759081B2 (en) 2010-07-20
ES2259609T3 (es) 2006-10-16
EP1734368A2 (en) 2006-12-20
EP2051079A3 (en) 2009-06-10
EP1200832A1 (en) 2002-05-02
DE60041839D1 (de) 2009-04-30
EP1200832B1 (en) 2006-05-17
US6645465B2 (en) 2003-11-11
US20100330587A1 (en) 2010-12-30
ATE426167T1 (de) 2009-04-15
EP1734368B1 (en) 2009-03-18
ATE529751T1 (de) 2011-11-15
EP2051079B1 (en) 2011-10-19
ATE326699T1 (de) 2006-06-15
EP1734368A3 (en) 2007-03-07
WO2001011372A1 (en) 2001-02-15
JP2003535309A (ja) 2003-11-25
AU780772B2 (en) 2005-04-14
US20040048320A1 (en) 2004-03-11
EP2051079A2 (en) 2009-04-22
DK1200832T3 (da) 2006-09-18
AU6526200A (en) 2001-03-05
CA2380398C (en) 2017-01-31
JP4594575B2 (ja) 2010-12-08
US20020168696A1 (en) 2002-11-14
US20060275845A1 (en) 2006-12-07
CA2380398A1 (en) 2001-02-15
US7955602B2 (en) 2011-06-07
DE60028040D1 (de) 2006-06-22
ES2320585T3 (es) 2009-05-25
US20070037227A1 (en) 2007-02-15
WO2001011372A9 (en) 2002-04-11
DE60028040T2 (de) 2006-11-23

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