DK3723790T3 - Fremgangsmåder til inducering af immuntolerance og reduktion af anti-lægemiddel-antistofrespons - Google Patents
Fremgangsmåder til inducering af immuntolerance og reduktion af anti-lægemiddel-antistofrespons Download PDFInfo
- Publication number
- DK3723790T3 DK3723790T3 DK18889387.9T DK18889387T DK3723790T3 DK 3723790 T3 DK3723790 T3 DK 3723790T3 DK 18889387 T DK18889387 T DK 18889387T DK 3723790 T3 DK3723790 T3 DK 3723790T3
- Authority
- DK
- Denmark
- Prior art keywords
- immunotolerance
- induction
- drug
- reduction
- methods
- Prior art date
Links
- 230000006058 immune tolerance Effects 0.000 title 1
- 230000006698 induction Effects 0.000 title 1
- 230000004044 response Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/577—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 tolerising response
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Transplantation (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762597441P | 2017-12-12 | 2017-12-12 | |
| PCT/IL2018/051342 WO2019116367A1 (en) | 2017-12-12 | 2018-12-10 | Methods of inducing immune tolerance and reducing anti-drug antibody response |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3723790T3 true DK3723790T3 (da) | 2024-04-22 |
Family
ID=66820781
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18889387.9T DK3723790T3 (da) | 2017-12-12 | 2018-12-10 | Fremgangsmåder til inducering af immuntolerance og reduktion af anti-lægemiddel-antistofrespons |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20210008183A1 (da) |
| EP (1) | EP3723790B1 (da) |
| CA (1) | CA3085696A1 (da) |
| DK (1) | DK3723790T3 (da) |
| ES (1) | ES2984415T3 (da) |
| FI (1) | FI3723790T3 (da) |
| IL (1) | IL275328B2 (da) |
| PL (1) | PL3723790T3 (da) |
| PT (1) | PT3723790T (da) |
| WO (1) | WO2019116367A1 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2757875C1 (ru) * | 2020-11-13 | 2021-10-22 | Генфа Глобал Лб (Лабораторис Биофармасьютика) Са | Применение ингибитора альфа1-протеиназы (альфа1-антитрипсина) для профилактики и/или лечения острого респираторного дистресс синдрома и способ профилактики и/или лечения острого респираторного дистресс синдрома с использованием альфа1-антитрипсина |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5218091A (en) | 1982-08-13 | 1993-06-08 | Zymogenetics, Inc. | Glycolytic promoters for regulated protein expression: protease inhibitor |
| US4711848A (en) | 1984-03-14 | 1987-12-08 | Zymogenetics, Inc. | Site specific mutagenesis in alpha-1-antitrypsin |
| US4931373A (en) | 1984-05-25 | 1990-06-05 | Zymogenetics, Inc. | Stable DNA constructs for expression of α-1 antitrypsin |
| US4732973A (en) | 1984-06-14 | 1988-03-22 | Chiron Corporation | Active site modified protease α-1-antitrypsin inhibitors |
| WO1986000337A1 (fr) | 1984-06-19 | 1986-01-16 | Transgene S.A. | DERIVES DE L'alpha1-ANTITRYPSINE HUMAINE ET PROCEDE POUR LEUR PREPARATION |
| US5366894A (en) | 1986-06-30 | 1994-11-22 | Pharmaceutical Proteins Limited | Peptide production |
| US5093316A (en) | 1986-12-24 | 1992-03-03 | John Lezdey | Treatment of inflammation |
| JP2656944B2 (ja) | 1987-04-30 | 1997-09-24 | クーパー ラボラトリーズ | タンパク質性治療剤のエアロゾール化 |
| US5079336A (en) | 1989-06-23 | 1992-01-07 | The Trustees Of The University Of Pennsylvania | α-1-antichymotrypsin, analogues and methods of production |
| US5134119A (en) | 1990-10-16 | 1992-07-28 | Lezdey John | Treatment of inflammation using 358 substituted alpha-antitrypsin |
| US5780440A (en) | 1996-06-17 | 1998-07-14 | Protease Sciences Inc. | Treatment of pulmonary disease with protease inhibitors |
| US5948407A (en) * | 1997-03-19 | 1999-09-07 | Shire Laboratories Inc. | Oral induction of tolerance to parenterally administered non-autologous polypeptides |
| EE200000546A (et) | 1998-03-16 | 2002-02-15 | Inhale Therapeutic Systems, Inc. | Aerosoolistatud toimeaine manustamissüsteem |
| DK1071806T3 (da) * | 1998-04-24 | 2004-07-19 | Univ Florida | Rekombinant adeno-associeret virus-vektor, der koder for alpha-1-antitrypsin i genterapi |
| DE19953317C1 (de) | 1999-11-05 | 2001-02-01 | Pari Gmbh | Inhalationsvernebler |
| US20040096456A1 (en) * | 2000-12-01 | 2004-05-20 | Conti-Fine Bianca M | Method to treat hemophilia |
| WO2004024655A2 (en) * | 2002-09-12 | 2004-03-25 | Avanir Pharmaceuticals | Phenyl-indole compounds for modulating ige and inhibiting cellular proliferation |
| ATE391730T1 (de) | 2003-09-22 | 2008-04-15 | Kamada Ltd | Herstellung eines alpha-1-proteinaseinhibitors im grossmassstab und dessen verwendung |
| CA2641872A1 (en) * | 2006-02-09 | 2007-08-16 | Kamada Ltd. | Alpha-i antitrypsin for treating exacerbation episodes of pulmonary diseases |
| WO2018154568A1 (en) * | 2017-02-21 | 2018-08-30 | Kamada Ltd. | Methods and uses of alpha 1-antitrypsin for early intervention in pulmonary diseases |
-
2018
- 2018-12-10 US US16/772,407 patent/US20210008183A1/en not_active Abandoned
- 2018-12-10 CA CA3085696A patent/CA3085696A1/en active Pending
- 2018-12-10 PT PT188893879T patent/PT3723790T/pt unknown
- 2018-12-10 DK DK18889387.9T patent/DK3723790T3/da active
- 2018-12-10 FI FIEP18889387.9T patent/FI3723790T3/fi active
- 2018-12-10 WO PCT/IL2018/051342 patent/WO2019116367A1/en not_active Ceased
- 2018-12-10 EP EP18889387.9A patent/EP3723790B1/en active Active
- 2018-12-10 PL PL18889387.9T patent/PL3723790T3/pl unknown
- 2018-12-10 ES ES18889387T patent/ES2984415T3/es active Active
- 2018-12-10 IL IL275328A patent/IL275328B2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL275328B1 (en) | 2023-11-01 |
| US20210008183A1 (en) | 2021-01-14 |
| PL3723790T3 (pl) | 2024-05-13 |
| PT3723790T (pt) | 2024-05-10 |
| EP3723790A1 (en) | 2020-10-21 |
| IL275328B2 (en) | 2024-03-01 |
| CA3085696A1 (en) | 2019-06-20 |
| FI3723790T3 (fi) | 2024-04-19 |
| ES2984415T3 (es) | 2024-10-29 |
| EP3723790B1 (en) | 2024-03-13 |
| IL275328A (en) | 2020-07-30 |
| WO2019116367A1 (en) | 2019-06-20 |
| EP3723790A4 (en) | 2021-09-15 |
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