EP0901629A4 - LIGAND LIBRARY BASED ON CARBON HYDRATES, ASSAY AND METHOD THEREOF - Google Patents

LIGAND LIBRARY BASED ON CARBON HYDRATES, ASSAY AND METHOD THEREOF

Info

Publication number: EP0901629A4
Authority: EP; European Patent Office
Prior art keywords: assay; library based; ligand library; carbon hydrates; hydrates
Prior art date: 1996-03-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP97916164A

Other languages

German (de)

French (fr)

Other versions

EP0901629A1 (en

Inventor

Daniel E Kahne

Jennifer Loebach

Lin Yan

Rui Liang

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Princeton University

Original Assignee

Princeton University

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-03-21

Filing date

1997-03-21

Publication date

2000-02-02

1997-03-21 Application filed by Princeton University filed Critical Princeton University

1999-03-17 Publication of EP0901629A1 publication Critical patent/EP0901629A1/en

2000-02-02 Publication of EP0901629A4 publication Critical patent/EP0901629A4/en

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Investigating Or Analysing Biological Materials (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

EP97916164A 1996-03-21 1997-03-21 LIGAND LIBRARY BASED ON CARBON HYDRATES, ASSAY AND METHOD THEREOF Withdrawn EP0901629A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US1537996P	1996-03-21	1996-03-21
US15379P		1996-03-21
PCT/US1997/004639 WO1997035202A1 (en)	1996-03-21	1997-03-21	Carbohydrate-based ligand library, assay and method

Publications (2)

Publication Number	Publication Date
EP0901629A1 EP0901629A1 (en)	1999-03-17
EP0901629A4 true EP0901629A4 (en)	2000-02-02

Family

ID=21771058

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP97916164A Withdrawn EP0901629A4 (en)	1996-03-21	1997-03-21	LIGAND LIBRARY BASED ON CARBON HYDRATES, ASSAY AND METHOD THEREOF

Country Status (4)

Country	Link
EP (1)	EP0901629A4 (en)
AU (1)	AU2341397A (en)
CA (1)	CA2249290A1 (en)
WO (1)	WO1997035202A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6040433A (en) *	1996-03-21	2000-03-21	The Trustees Of Princeton University	Sulfinyl hexose derivatives useful for glycosylation
WO1998011436A1 (en) *	1996-09-13	1998-03-19	Whitehead Institute For Biomedical Research	Non-specific affinity enhancement to identify combinatorial library members
WO1999061583A2 (en) *	1998-05-28	1999-12-02	Incara Pharmaceuticals Corp.	Carbohydrate-based scaffold compounds, combinatorial libraries and methods for their construction
US6998233B2 (en)	1998-06-26	2006-02-14	Sunesis Pharmaceuticals, Inc.	Methods for ligand discovery
US6919178B2 (en)	2000-11-21	2005-07-19	Sunesis Pharmaceuticals, Inc.	Extended tethering approach for rapid identification of ligands
US6335155B1 (en)	1998-06-26	2002-01-01	Sunesis Pharmaceuticals, Inc.	Methods for rapidly identifying small organic molecule ligands for binding to biological target molecules
EP1147129A4 (en) *	1999-01-12	2003-01-15	Univ Princeton	SACCHARID COUPLED TO SUBSTANCES THAT BIND CELL SURFACE PEPTIDES OR PROTEINS.
US20010051349A1 (en)	2000-02-17	2001-12-13	Glycominds Ltd.	Combinatorial complex carbohydrate libraries and methods for the manufacture and uses thereof
US6579725B1 (en)	1999-03-05	2003-06-17	Massachusetts Institute Of Technology	Linkers for synthesis of oligosaccharides on solid supports
US20020098513A1 (en) *	2000-02-17	2002-07-25	Glycominds Ltd.	Combinatorial complex carbohydrate libraries and methods for the manufacture and uses thereof
US6656694B2 (en) *	2001-01-11	2003-12-02	Theravance, Inc.	Method for identifying a ligand for a biological substrate
US20040082079A1 (en) *	2001-02-05	2004-04-29	Ralf Besenbruch	Low affinity screening method
WO2002063303A1 (en) *	2001-02-07	2002-08-15	Graffinity Pharmaceuticals Ag	Screening method using solid supports modified with self-assembled monolayers

Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0601417A2 (en) *	1992-12-11	1994-06-15	Hoechst Aktiengesellschaft	Physiologically compatible and degradable polymer-based carbohydrate receptor blockers, a method for their preparation and their use
WO1994019360A1 (en) *	1993-02-23	1994-09-01	The Trustees Of Princeton University	Solution and solid-phase formation of glycosidic linkages
WO1995003315A2 (en) *	1993-07-21	1995-02-02	Oxford Glycosystems Ltd	Saccharides, their synthesis and use
WO1996036627A1 (en) *	1995-05-19	1996-11-21	Glycomed Incorporated	Collection of activated glycoside compounds and their biological use

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US5650489A (en) *	1990-07-02	1997-07-22	The Arizona Board Of Regents	Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
AU1602995A (en) *	1994-01-11	1995-08-01	Affymax Technologies N.V.	Methods for the solid phase synthesis of glycoconjugates
US5575324A (en) *	1995-04-07	1996-11-19	Hwang; Charles	Sunshield and method of manufacture of sunshield

1997
- 1997-03-21 WO PCT/US1997/004639 patent/WO1997035202A1/en not_active Application Discontinuation
- 1997-03-21 AU AU23413/97A patent/AU2341397A/en not_active Abandoned
- 1997-03-21 CA CA 2249290 patent/CA2249290A1/en not_active Abandoned
- 1997-03-21 EP EP97916164A patent/EP0901629A4/en not_active Withdrawn

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0601417A2 (en) *	1992-12-11	1994-06-15	Hoechst Aktiengesellschaft	Physiologically compatible and degradable polymer-based carbohydrate receptor blockers, a method for their preparation and their use
WO1994019360A1 (en) *	1993-02-23	1994-09-01	The Trustees Of Princeton University	Solution and solid-phase formation of glycosidic linkages
WO1995003315A2 (en) *	1993-07-21	1995-02-02	Oxford Glycosystems Ltd	Saccharides, their synthesis and use
WO1996036627A1 (en) *	1995-05-19	1996-11-21	Glycomed Incorporated	Collection of activated glycoside compounds and their biological use

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
BAMHAOUD T ET AL: "A NOVEL APPROACH TO THE CONSTRUCTION OF HYDROXYLAMINO INTERGLYCOSIDIC LINKAGES", JOURNAL OF THE CHEMICAL SOCIETY, CHEMICAL COMMUNICATIONS,GB,CHEMICAL SOCIETY. LETCHWORTH, no. 20, 1992, pages 1494-1496, XP000857310, ISSN: 0022-4936 *
BECKER D ET AL: "SYNTHESIS AND UTILIZATION OF SACCHARIDE INTERMEDIATES", CARBOHYDRATE RESEARCH,NL,ELSEVIER SCIENTIFIC PUBLISHING COMPANY. AMSTERDAM, vol. 248, 1993, pages 129-141, XP000857309, ISSN: 0008-6215 *
JOHNSTON J N ET AL: "Studies directed toward the total synthesis of polycavernoside A. enantioselective synthesis of the disaccharide component", TETRAHEDRON LETTERS,NL,ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, vol. 36, no. 25, 1995, pages 4341-4344, XP004027848, ISSN: 0040-4039 *
NICOLAOU K C ET AL: "TOTAL SYNTHESIS OF THE TUMOR-ASSOCIATED LEX FAMILY OF GLYCOSPHINGOLIPIDS", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,US,AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, vol. 112, pages 3693-3695, XP000601632, ISSN: 0002-7863 *
S.CAO ET AL.: "Phase Transfer Catalyzed Anomeric Nucleophilic Substitutions Occur by an SN2-Type Mechanism.", CARBOHYDRATE LETTERS, vol. 2, no. 1, 1996, pages 27 - 34, XP000856877 *
S.KOMBA ET AL.: "Synthesis and Biological Activities of Three Sulfates Sialyl Lex Ganglioside Analogues for Clarifying the Real Carbohydrate Ligand Structure of L-Selectin.", BIOORGANIC AND MEDICINAL CHEMISTRY, vol. 4, no. 11, November 1996 (1996-11-01), pages 1833 - 1847, XP000856927 *
See also references of WO9735202A1 *

Also Published As

Publication number	Publication date
CA2249290A1 (en)	1997-09-25
EP0901629A1 (en)	1999-03-17
AU2341397A (en)	1997-10-10
WO1997035202A1 (en)	1997-09-25

Publication	Publication Date	Title
EP0901629A4 (en)	2000-02-02	LIGAND LIBRARY BASED ON CARBON HYDRATES, ASSAY AND METHOD THEREOF
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DE69513997D1 (en)	2000-01-20	MASSIVE PARALLEL SEQUENCING ON SORTED POLYNUCLEOTIDES
FI955542A0 (en)	1995-11-16	Carbon compounds and methods for making a non-conductive electroplating agent
MX163490B (en)	1992-05-22	NEW CARBON AND ETHENE MONOXIDE POLYMERS
FI960006A0 (en)	1996-01-02	Immunoassay for soluble fibrin polymers
FI955979A7 (en)	1995-12-13	Sustained-release, film-coated astemizole and pseudoephedrine tablet
DE69811131D1 (en)	2003-03-13	Optical-active phosphine derivatives containing at least two vinyl groups, derived polymers and their transition metal complexes
IT8720510A0 (en)	1987-05-14	COMPOUNDS BASED ON VINYL-AROMATIC POLYMERS WITH HIGH TOUGHNESS AND CHEMICAL RESISTANCE.
DE69624839D1 (en)	2002-12-19	SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS.
NO960369D0 (en)	1996-01-29	Organometallic compounds, and polymers made therefrom
DE69003013D1 (en)	1993-10-07	Polymers containing aminophosphonates.
DE69725940D1 (en)	2003-12-11	Carrier plate detector and connector with such a detector
DE68922152D1 (en)	1995-05-18	Carbon monoxide copolymers.
DE69014912D1 (en)	1995-01-26	Polymerizable compound and polymers thereof.
DE59008078D1 (en)	1995-02-02	System for operating a portable lamp.
FR2730076B1 (en)	1997-03-28	METHOD FOR AUTHENTICATING BY A SERVER THE CARRIER OF A PORTABLE OBJECT WITH MICROPROCESSOR, CORRESPONDING SERVER AND PORTABLE OBJECT
FR2780725B1 (en)	2000-09-29	FERTILIZER BASED ON WATERPROOFER (S)
FI946015A7 (en)	1996-01-09	Electroless contact nodule formation method
FR2775005B1 (en)	2000-05-26	COATING BASED ON ULTRA-HARD AND FLEXIBLE CARBON NITRIDE AND PREPARATION METHOD THEREOF
KR960705586A (en)	1996-11-08	Sustained-release preparation base, sustained-release preparation, and preparation method thereof
NO994012D0 (en)	1999-08-19	Procedure for processing a base material for specific properties
FR2703085B1 (en)	1995-06-16	MIXER AND METHOD FOR COATING A GRANULAR MATERIAL.
FR2697054B1 (en)	1994-11-18	Rotor-type device with induced destabilization for moving a mobile.

Legal Events

Date	Code	Title	Description
1999-01-29	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1999-03-17	17P	Request for examination filed	Effective date: 19980921
1999-03-17	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
1999-05-06	RIN1	Information on inventor provided before grant (corrected)	Inventor name: LIANG, RUI Inventor name: YAN, LIN Inventor name: LOEBACH, JENNIFER Inventor name: KAHNE, DANIEL, E.
2000-02-02	A4	Supplementary search report drawn up and despatched	Effective date: 19991220
2000-02-02	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2000-02-02	RIC1	Information provided on ipc code assigned before grant	Free format text: 7G 01N 33/543 A, 7C 12N 9/00 B, 7C 07H 5/08 B, 7C 07H 15/12 B, 7C 07H 15/14 B, 7A 61K 39/385 B, 7C 07H 1/00 B
2002-03-13	17Q	First examination report despatched	Effective date: 20020128
2002-10-25	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2002-12-11	18D	Application deemed to be withdrawn	Effective date: 20020608