EP1053315A4 - GENE OF CALVITIS IN MEN, PROTEIN AND USES THEREOF - Google Patents

GENE OF CALVITIS IN MEN, PROTEIN AND USES THEREOF

Info

Publication number: EP1053315A4
Authority: EP; European Patent Office
Prior art keywords: calvitis; men; gene; protein
Prior art date: 1998-01-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

EP99905596A

Other languages

German (de)

French (fr)

Other versions

EP1053315A1 (en

Inventor

Angela M Christiano

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Columbia University in the City of New York

Original Assignee

Columbia University in the City of New York

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-01-29

Filing date

1999-01-29

Publication date

2003-07-30

1999-01-29 Application filed by Columbia University in the City of New York filed Critical Columbia University in the City of New York

2000-11-22 Publication of EP1053315A1 publication Critical patent/EP1053315A1/en

2003-07-30 Publication of EP1053315A4 publication Critical patent/EP1053315A4/en

Status Pending legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/606—Nucleosides; Nucleotides; Nucleic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
- A61Q7/02—Preparations for inhibiting or slowing hair growth
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/86—Products or compounds obtained by genetic engineering
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Birds (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Dermatology (AREA)
Organic Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

EP99905596A 1998-01-29 1999-01-29 GENE OF CALVITIS IN MEN, PROTEIN AND USES THEREOF Pending EP1053315A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US7304398P	1998-01-29	1998-01-29
US73043P		1998-01-29
PCT/US1999/002128 WO1999038965A1 (en)	1998-01-29	1999-01-29	Human hairless gene, protein and uses thereof

Publications (2)

Publication Number	Publication Date
EP1053315A1 EP1053315A1 (en)	2000-11-22
EP1053315A4 true EP1053315A4 (en)	2003-07-30

Family

ID=22111367

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP99905596A Pending EP1053315A4 (en)	1998-01-29	1999-01-29	GENE OF CALVITIS IN MEN, PROTEIN AND USES THEREOF

Country Status (4)

Country	Link
EP (1)	EP1053315A4 (en)
AU (1)	AU2572499A (en)
CA (1)	CA2362320A1 (en)
WO (1)	WO1999038965A1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6348348B1 (en)	1998-04-07	2002-02-19	The Carnegie Institution Of Washington	Human hairless gene and protein
GB0011269D0 (en) *	2000-05-11	2000-06-28	Univ Sheffield	Protein over expression
EP1368493A2 (en)	2001-03-07	2003-12-10	Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.	Identification and use of inhibitors of hair growth
ATE489466T1 (en)	2001-04-13	2010-12-15	Univ Columbia	NUCLEIC ACIDS FOR INHIBITING HAIRLESS PROTEIN EXPRESSION AND METHOD FOR USE THEREOF
US7169564B1 (en)	2001-06-26	2007-01-30	Anaderm Research Corporation	FKBP51/52 and CyP40-mediated mammalian hair growth
EP1399579A4 (en) *	2001-06-26	2006-04-19	Anaderm Res Corp	Fkbp51/52 and cyp40-mediated mammalian hair growth
US10011836B2 (en)	2002-11-14	2018-07-03	Thermo Fisher Scientific Inc.	Methods and compositions for selecting siRNA of improved functionality
US9719092B2 (en)	2002-11-14	2017-08-01	Thermo Fisher Scientific Inc.	RNAi targeting CNTD2
US9228186B2 (en)	2002-11-14	2016-01-05	Thermo Fisher Scientific Inc.	Methods and compositions for selecting siRNA of improved functionality
US9719094B2 (en)	2002-11-14	2017-08-01	Thermo Fisher Scientific Inc.	RNAi targeting SEC61G
US9879266B2 (en)	2002-11-14	2018-01-30	Thermo Fisher Scientific Inc.	Methods and compositions for selecting siRNA of improved functionality
US9839649B2 (en)	2002-11-14	2017-12-12	Thermo Fisher Scientific Inc.	Methods and compositions for selecting siRNA of improved functionality
US9771586B2 (en)	2002-11-14	2017-09-26	Thermo Fisher Scientific Inc.	RNAi targeting ZNF205
ATE517992T1 (en)	2002-11-14	2011-08-15	Dharmacon Inc	FUNCTIONAL AND HYPERFUNCTIONAL SIRNA
WO2006006948A2 (en)	2002-11-14	2006-01-19	Dharmacon, Inc.	METHODS AND COMPOSITIONS FOR SELECTING siRNA OF IMPROVED FUNCTIONALITY
US7612196B2 (en)	2002-11-14	2009-11-03	Dharmacon, Inc.	siRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B)
US20050106141A1 (en) *	2003-11-13	2005-05-19	The Procter & Gamble Company	Hairless protein-interacting partner complexes and methods thereof for the beautification and/or improvement of mammalian skin
AU2005238034A1 (en)	2004-04-23	2005-11-10	The Trustees Of Columbia University In The City Of New York	Inhibition of hairless protein mRNA
US8168600B2 (en)	2004-04-23	2012-05-01	Isis Pharmaceuticals, Inc.	Compositions and methods for topical delivery of oligonucleotides
WO2014022655A1 (en) *	2012-08-01	2014-02-06	The Trustees Of Columbia University In The City Of New York	Methods for regulating hair growth disorders
EP2735303A1 (en) *	2012-11-23	2014-05-28	Pilosciences	Hair growth compositions and methods
WO2019161805A1 (en) *	2018-02-26	2019-08-29	Biocytogen Jiangsu Co., Ltd.	Hr knockout non-human animal
CN113717975B (en) *	2021-09-01	2023-09-26	中国农业大学	A kind of miRNA marker related to the hairless trait of pigs and its application

1999
- 1999-01-29 CA CA002362320A patent/CA2362320A1/en not_active Abandoned
- 1999-01-29 EP EP99905596A patent/EP1053315A4/en active Pending
- 1999-01-29 AU AU25724/99A patent/AU2572499A/en not_active Abandoned
- 1999-01-29 WO PCT/US1999/002128 patent/WO1999038965A1/en not_active Application Discontinuation

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
AHMAD W ET AL: "ALOPECIA UNIVERSALIS ASSOCIATED WITH A MUTATION IN THE HUMAN HAIRLESS GENE", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 279, 30 January 1998 (1998-01-30), pages 720 - 724, XP000971022, ISSN: 0036-8075 *
AHMAD WASIM ET AL: "A missense mutation in the zinc-finger domain of the human hairless gene underlies congenital atrichia in a family of Irish travellers.", AMERICAN JOURNAL OF HUMAN GENETICS, vol. 63, no. 4, October 1998 (1998-10-01), pages 984 - 991, XP002241689, ISSN: 0002-9297 *
CACHON-GONZALEZ M B ET AL: "STRUCTURE AND EXPRESSION OF THE HAIRLESS GENE OF MICE", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 91, August 1994 (1994-08-01), pages 7717 - 7721, XP002933874, ISSN: 0027-8424 *
CICHON S ET AL: "CLONING, GENOMIC ORGANIZATION, ALTERNATIVE TRANSCRIPTS AND MUTATIONAL ANALYSIS OF THE GENE RESPONSIBLE FOR AUTOSOMAL RECESSIVEUNIVERSAL CONGENITAL ALOPECIA", HUMAN MOLECULAR GENETICS, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 7, no. 11, October 1998 (1998-10-01), pages 1671 - 1679, XP000971023, ISSN: 0964-6906 *
DATABASE EMBL [online] 16 August 1996 (1996-08-16), HILLIER L. ET AL.: "ze85d02.r1 Soares_fetal_heart_NbHH19W Homo sapiens cDNA clone IMAGE:365763 5', mRNA sequence", XP002241691, Database accession no. AA025648 *
FRANK J ET AL: "Exposing the human nude phenotype.", NATURE. ENGLAND 8 APR 1999, vol. 398, no. 6727, 8 April 1999 (1999-04-08), pages 473 - 474, XP002241688, ISSN: 0028-0836 *
SCHORPP M ET AL: "CHARACTERIZATION OF MOUSE AND HUMAN NUDE GENES", IMMUNOGENETICS, SPRINGER VERLAG, BERLIN, DE, vol. 46, no. 6, November 1997 (1997-11-01), pages 509 - 515, XP000876601, ISSN: 0093-7711 *
See also references of WO9938965A1 *
SEGRE J A ET AL: "POSITIONAL CLONING OF THE NUDE LOCUS: GENETIC, PHYSICAL AND TRANSCRIPTION MAPS OF THE REGION AND MUTATIONS IN THE MOUSE AND RAT", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, vol. 28, no. 3, 10 August 1995 (1995-08-10), pages 549 - 559, XP001041492, ISSN: 0888-7543 *
THOMPSON CATHERINE C: "Thyroid hormone-responsive genes in developing cerebellum include a novel synaptotagmin and a hairless homolog.", JOURNAL OF NEUROSCIENCE, vol. 16, no. 24, 1996, pages 7832 - 7840, XP002241687, ISSN: 0270-6474 *
ZLOTOGORSKI ABRAHAM ET AL: "Congenital atrichia in five Arab Palestinian families resulting from a deletion mutation in the human hairless gene.", HUMAN GENETICS, vol. 103, no. 4, October 1998 (1998-10-01), pages 400 - 404, XP002241690, ISSN: 0340-6717 *

Also Published As

Publication number	Publication date
EP1053315A1 (en)	2000-11-22
WO1999038965A1 (en)	1999-08-05
CA2362320A1 (en)	1999-08-05
AU2572499A (en)	1999-08-16

Publication	Publication Date	Title
EP1053315A4 (en)	2003-07-30	GENE OF CALVITIS IN MEN, PROTEIN AND USES THEREOF
EP1165586A4 (en)	2003-05-28	TCL-1b GENE AND PROTEIN, METHODS AND COMPOSITIONS RELATING thereto
LU91437I2 (en)	2008-07-14	"dabigatran-etexilate and its salts - particularly dabigatran-etexilate-mesilate (PRADAXA)"
EP1018987A4 (en)	2004-12-15	NEOCARTILAGE AND ITS METHODS OF USE
PT1108039E (en)	2008-07-11	GENES OF ALONGASES AND THEIR USES
ATE312597T1 (en)	2005-12-15	USE OF NANODISPERSIONS IN FINAL PHARMACEUTICAL FORMULATIONS
EP0977836A4 (en)	2002-10-16	"LEAFY COTYLEDON 1" TYPE GENES AND THEIR USE
NL300295I2 (en)	2008-03-03	3,3-diarylpropylamines, their use and preparation
DE69825625D1 (en)	2004-09-16	AMINOBIGUANIDES AND THEIR USE FOR DISINFECTING CONTACT LENSES AND PRESERVATING PHARMACEUTICAL PREPARATIONS
AU3510200A (en)	2000-09-21	Human dickkopf-related protein and nucleic acid molecules and uses therefor
EP0853486A3 (en)	1997-06-12	Therapeutic applications of animal sera including horse serum in the treatment of aids, cancer, and other viral and bacterial diseases
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EP1047773A4 (en)	2004-12-29	CUBILIN PROTEIN, DNA SEQUENCES ENCODING CUBILIN, AND USES THEREOF
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EP1124840A4 (en)	2002-07-17	OVAR-SPECIFIC GENES AND PROTEINS
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AU2001297556A1 (en)	2002-10-03	38650, 28472, 5495, 65507, 81588 and 14354 methods and compositions of human proteins and uses thereof

Legal Events

Date	Code	Title	Description
2000-10-06	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2000-11-22	17P	Request for examination filed	Effective date: 20000828
2000-11-22	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2003-05-02	18D	Application deemed to be withdrawn	Effective date: 20020801
2003-06-20	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2003-07-09	D18D	Application deemed to be withdrawn (deleted)
2003-07-23	R18D	Application deemed to be withdrawn (corrected)	Effective date: 20020801
2003-07-30	A4	Supplementary search report drawn up and despatched	Effective date: 20030617
2003-07-30	D18D	Application deemed to be withdrawn (deleted)
2003-08-06	R18D	Application deemed to be withdrawn (corrected)	Effective date: 20020801