EP1012333A4 - ISOLATION OF A NEW GENE p23 FROM THE SENESCENCE FACTOR - Google Patents

ISOLATION OF A NEW GENE p23 FROM THE SENESCENCE FACTOR

Info

Publication number: EP1012333A4
Authority: EP; European Patent Office
Prior art keywords: isolation; new gene; senescence factor; senescence; factor
Prior art date: 1997-08-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP98938406A

Other languages

German (de)

French (fr)

Other versions

EP1012333A1 (en

Inventor

Karen Swisshelm

Suzanne Hosier

Manfred Kubbies

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

University of Washington

Original Assignee

University of Washington

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-08-08

Filing date

1998-08-05

Publication date

2003-01-02

1998-08-05 Application filed by University of Washington filed Critical University of Washington

2000-06-28 Publication of EP1012333A1 publication Critical patent/EP1012333A1/en

2003-01-02 Publication of EP1012333A4 publication Critical patent/EP1012333A4/en

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4738—Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Biomedical Technology (AREA)
General Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Cell Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
Immunology (AREA)
Plant Pathology (AREA)
Crystallography & Structural Chemistry (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

EP98938406A 1997-08-08 1998-08-05 ISOLATION OF A NEW GENE p23 FROM THE SENESCENCE FACTOR Withdrawn EP1012333A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US90887397A	1997-08-08	1997-08-08
US908873		1997-08-08
PCT/US1998/016343 WO1999007893A1 (en)	1997-08-08	1998-08-05	ISOLATION OF A NOVEL SENESCENCE-FACTOR GENE, p23

Publications (2)

Publication Number	Publication Date
EP1012333A1 EP1012333A1 (en)	2000-06-28
EP1012333A4 true EP1012333A4 (en)	2003-01-02

Family

ID=25426353

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP98938406A Withdrawn EP1012333A4 (en)	1997-08-08	1998-08-05	ISOLATION OF A NEW GENE p23 FROM THE SENESCENCE FACTOR

Country Status (9)

Country	Link
EP (1)	EP1012333A4 (en)
JP (1)	JP2001512698A (en)
KR (1)	KR20010022741A (en)
CN (1)	CN1270637A (en)
AU (1)	AU8693598A (en)
BR (1)	BR9811865A (en)
CA (1)	CA2296598A1 (en)
TR (1)	TR200000331T2 (en)
WO (1)	WO1999007893A1 (en)

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2002024721A1 (en) *	2000-09-20	2002-03-28	Human Genome Sciences, Inc.	21 human secreted proteins
ATE463566T1 (en) *	2000-01-21	2010-04-15	Polymun Scient Immunbio Forsch	TUMOR AND SENSENCE MARKERS
AU750296B2 (en)	2000-06-23	2002-07-11	F. Hoffmann-La Roche Ag	Antibodies against SEMP1, methods for their production and uses thereof
WO2002101075A2 (en)	2001-06-13	2002-12-19	Millennium Pharmaceuticals, Inc.	Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of cervical cancer
DK2789684T3 (en)	2008-05-23	2017-02-20	Siwa Corp	Methods and compositions for facilitating regeneration
US9649376B2 (en)	2010-09-27	2017-05-16	Siwa Corporation	Selective removal of age-modified cells for treatment of atherosclerosis
US8721571B2 (en)	2010-11-22	2014-05-13	Siwa Corporation	Selective removal of cells having accumulated agents
CN107001459B (en)	2014-09-19	2021-11-23	Siwa有限公司	anti-AGE antibodies for the treatment of inflammatory and autoimmune disorders
US10358502B2 (en)	2014-12-18	2019-07-23	Siwa Corporation	Product and method for treating sarcopenia
US9993535B2 (en)	2014-12-18	2018-06-12	Siwa Corporation	Method and composition for treating sarcopenia
ES2912064T3 (en)	2016-02-19	2022-05-24	Siwa Corp	Method and composition for treating cancer, killing metastatic cancer cells, and preventing cancer metastasis using antibody to advanced glycation end products (AGEs)
WO2018191718A1 (en)	2017-04-13	2018-10-18	Siwa Corporation	Humanized monoclonal advanced glycation end-product antibody
KR20180133452A (en)	2016-04-15	2018-12-14	시와 코퍼레이션	Anti-aging antibodies to treat neurodegenerative diseases
JP2019518763A (en)	2016-06-23	2019-07-04	シワコーポレーション	Vaccines for use in the treatment of various diseases and disorders
US10961321B1 (en)	2017-01-06	2021-03-30	Siwa Corporation	Methods and compositions for treating pain associated with inflammation
US10858449B1 (en)	2017-01-06	2020-12-08	Siwa Corporation	Methods and compositions for treating osteoarthritis
US10925937B1 (en)	2017-01-06	2021-02-23	Siwa Corporation	Vaccines for use in treating juvenile disorders associated with inflammation
US10995151B1 (en)	2017-01-06	2021-05-04	Siwa Corporation	Methods and compositions for treating disease-related cachexia
US11518801B1 (en)	2017-12-22	2022-12-06	Siwa Corporation	Methods and compositions for treating diabetes and diabetic complications

Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1996013610A2 (en) *	1994-10-31	1996-05-09	Geron Corporation	Methods and reagents for the identification and regulation of senescence-related genes
WO1999007850A1 (en) *	1997-08-06	1999-02-18	Millennium Biotherapeutics, Inc.	Tango-71, tango-73, tango-74, tango-76, and tango-83 nucleic acid molecules and polypeptides
WO1999046281A2 (en) *	1998-03-10	1999-09-16	Genentech, Inc.	Novel polypeptides and nucleic acids encoding the same
WO2000000609A2 (en) *	1998-06-29	2000-01-06	Incyte Pharmaceuticals, Inc.	Molecules associated with apoptosis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5580726A (en) *	1994-04-29	1996-12-03	Geron Corporation	Method and Kit for enhanced differential display

1998
- 1998-08-05 EP EP98938406A patent/EP1012333A4/en not_active Withdrawn
- 1998-08-05 KR KR1020007001338A patent/KR20010022741A/en not_active Withdrawn
- 1998-08-05 WO PCT/US1998/016343 patent/WO1999007893A1/en active Search and Examination
- 1998-08-05 BR BR9811865-0A patent/BR9811865A/en not_active Application Discontinuation
- 1998-08-05 CN CN98807887A patent/CN1270637A/en active Pending
- 1998-08-05 AU AU86935/98A patent/AU8693598A/en not_active Abandoned
- 1998-08-05 TR TR2000/00331T patent/TR200000331T2/en unknown
- 1998-08-05 CA CA002296598A patent/CA2296598A1/en not_active Abandoned
- 1998-08-05 JP JP2000506375A patent/JP2001512698A/en not_active Withdrawn

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1996013610A2 (en) *	1994-10-31	1996-05-09	Geron Corporation	Methods and reagents for the identification and regulation of senescence-related genes
WO1999007850A1 (en) *	1997-08-06	1999-02-18	Millennium Biotherapeutics, Inc.	Tango-71, tango-73, tango-74, tango-76, and tango-83 nucleic acid molecules and polypeptides
WO1999046281A2 (en) *	1998-03-10	1999-09-16	Genentech, Inc.	Novel polypeptides and nucleic acids encoding the same
WO2000000609A2 (en) *	1998-06-29	2000-01-06	Incyte Pharmaceuticals, Inc.	Molecules associated with apoptosis

Non-Patent Citations (12)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 15 June 1999 (1999-06-15), "Human Tango-73 encoding cDNA", XP002217496, retrieved from EBI Database accession no. AAX19956 *
DATABASE EMBL [online] 15 June 1999 (1999-06-15), "Human Tango-73 protein", XP002217495, retrieved from EBI Database accession no. AAY04143 *
DATABASE EMBL [online] 5 May 2000 (2000-05-05), "cDNA encoding a human molecule associated with apoptosis 2 (MAPOP-2)", XP002217494, retrieved from EBI Database accession no. AAZ60459 *
DATABASE EMBL [online] 7 December 1999 (1999-12-07), "Human PRO944 nucleotide sequence", XP002217498, retrieved from EBI Database accession no. AAZ34118 *
DATABASE EMBL [online] 7 December 1999 (1999-12-07), "Human PRO944 protein sequence", XP002217497, retrieved from EBI Database accession no. AAY41726 *
DATABASE EMBLLEVANT [online] 5 May 2000 (2000-05-05), "A human molecule associated with apoptosis 2 (MAPOP-2)", XP002217493, retrieved from EBI Database accession no. AAY68679 *
FURUSE M ET AL: "CLAUDIN-1 AND -2: NOVEL INTEGRAL MEMBRANE PROTEINS LOCALIZING AT TIGHT JUNCTIONS WITH NO SEQUENCE SIMILARITY TO OCCLUDIN", JOURNAL OF CELL BIOLOGY, ROCKEFELLER UNIVERSITY PRESS, NEW YORK, US, US, vol. 141, no. 7, 29 June 1998 (1998-06-29), pages 1539 - 1550, XP001008152, ISSN: 0021-9525 *
JONASDOTTIR A. ET AL.: "Refinement of the dominant optic atrophy locus (OPA1) to a 1.4-cM interval on chromosome 3q28-3q29 within a 3-Mb YAC contig", ORIGINAL INVESTIGATION, vol. 99, 1997, pages 115 - 120, XP002217491 *
LINSKENS M H K ET AL: "CATALOGING ALTERED GENE EXPRESSION IN YOUNG AND SENESCENT CELLS USING ENHANCED DIFFERENTIAL DISPLAY", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 23, no. 16, 1995, pages 3244 - 3251, XP002047039, ISSN: 0305-1048 *
See also references of WO9907893A1 *
SMITH D. ET AL.: "Localization of 616 human chromosome 3-specific cosmids using a somatic cell hybrid deletion mapping panel", GENOMICS, vol. 11, September 1991 (1991-09-01), pages 179 - 187, XP001107125 *
SWISSHELM K ET AL: "SEMP1, a senescence-associated cDNA isolated from human mammary epithelial cells, is a member of an epithelial membrane protein superfamily", GENE, ELSEVIER BIOMEDICAL PRESS. AMSTERDAM, NL, vol. 226, no. 2, 21 January 1999 (1999-01-21), pages 285 - 295, XP004155143, ISSN: 0378-1119 *

Also Published As

Publication number	Publication date
TR200000331T2 (en)	2000-05-22
AU8693598A (en)	1999-03-01
CA2296598A1 (en)	1999-02-18
EP1012333A1 (en)	2000-06-28
KR20010022741A (en)	2001-03-26
CN1270637A (en)	2000-10-18
JP2001512698A (en)	2001-08-28
BR9811865A (en)	2000-08-15
WO1999007893A1 (en)	1999-02-18

Publication	Publication Date	Title
EP1012333A4 (en)	2003-01-02	ISOLATION OF A NEW GENE p23 FROM THE SENESCENCE FACTOR
PL340600A1 (en)	2001-02-12	Many times substituted varieties of protease
IL122477A (en)	2000-02-29	Expandable aircraft section
ID24757A (en)	2000-08-03	PRODUCT DETERGENT OF GRAIN
IL132452A0 (en)	2001-03-19	Preparation of hydroxy urethanes
GB9514435D0 (en)	1995-09-13	Inhibition of gene expression
IL133248A (en)	2003-11-23	Fungicide mixtures of methoxycarbamates
ZA9873B (en)	1998-07-08	Shower partition
EP0813874A4 (en)	1998-05-06	Remedy for pancreatitis
GB9602060D0 (en)	1996-04-03	Combined shower
ZA941093B (en)	1994-08-29	Shower partition
ZA963356B (en)	1996-07-30	Novel uses of heptafluoropropane
GB2322546B (en)	2001-02-07	Shower trays
SG64924A1 (en)	1999-05-25	Inhibiting photodecompostion of 3-substituted-2- oxindoles
GB9515854D0 (en)	1995-10-04	Spider inhibitor
GB9521173D0 (en)	1995-12-20	Isolation of parasites
TW367984U (en)	1999-08-21	Slide assembling structure for pulling-door of bathroom
TW355041U (en)	1999-03-21	Improvement of three section faucet
IT239251Y1 (en)	2001-02-26	ENAMELLED ENAMELLING CABIN
GB9703672D0 (en)	1997-04-09	Inhibition of gene expression
GB9703663D0 (en)	1997-04-09	Inhibition of gene expression
GB9706060D0 (en)	1997-05-14	Inhibition of gene expression
TW309934U (en)	1997-07-01	Structure of cigarrette shelf
TW361152U (en)	1999-06-11	New design of combined shelves
IT243309Y1 (en)	2002-03-04	CONTAINER - EXHIBITOR FOR PLURALITY OF OBJECTS

Legal Events

Date	Code	Title	Description
2000-05-12	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2000-06-28	17P	Request for examination filed	Effective date: 20000125
2000-06-28	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
2003-01-02	A4	Supplementary search report drawn up and despatched	Effective date: 20021113
2003-01-02	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
2003-06-20	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2003-08-06	18D	Application deemed to be withdrawn	Effective date: 20030116