[go: up one dir, main page]

EP1784502A4 - Fluorescent lifetime biological detection and imaging using water-stable semiconductor nanocrystals - Google Patents

Fluorescent lifetime biological detection and imaging using water-stable semiconductor nanocrystals

Info

Publication number
EP1784502A4
EP1784502A4 EP05769351A EP05769351A EP1784502A4 EP 1784502 A4 EP1784502 A4 EP 1784502A4 EP 05769351 A EP05769351 A EP 05769351A EP 05769351 A EP05769351 A EP 05769351A EP 1784502 A4 EP1784502 A4 EP 1784502A4
Authority
EP
European Patent Office
Prior art keywords
imaging
water
semiconductor nanocrystals
biological detection
fluorescent lifetime
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05769351A
Other languages
German (de)
French (fr)
Other versions
EP1784502A2 (en
Inventor
Wei Liu
Zuoyan Peng
Michael Locascio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evident Technologies Inc
Original Assignee
Evident Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/885,867 external-priority patent/US7192780B2/en
Application filed by Evident Technologies Inc filed Critical Evident Technologies Inc
Publication of EP1784502A2 publication Critical patent/EP1784502A2/en
Publication of EP1784502A4 publication Critical patent/EP1784502A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/588—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with semiconductor nanocrystal label, e.g. quantum dots

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nanotechnology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
EP05769351A 2004-07-08 2005-07-08 Fluorescent lifetime biological detection and imaging using water-stable semiconductor nanocrystals Withdrawn EP1784502A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/885,867 US7192780B2 (en) 2002-10-23 2004-07-08 Fluorescent lifetime biological detection and imaging using water-stable semiconductor nanocrystals
PCT/US2005/024211 WO2006014576A2 (en) 2002-10-23 2005-07-08 Fluorescent lifetime biological detection and imaging using water-stable semiconductor nanocrystals

Publications (2)

Publication Number Publication Date
EP1784502A2 EP1784502A2 (en) 2007-05-16
EP1784502A4 true EP1784502A4 (en) 2007-10-03

Family

ID=37872031

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05769351A Withdrawn EP1784502A4 (en) 2004-07-08 2005-07-08 Fluorescent lifetime biological detection and imaging using water-stable semiconductor nanocrystals

Country Status (2)

Country Link
EP (1) EP1784502A4 (en)
CA (1) CA2573150A1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040115817A1 (en) * 2002-10-23 2004-06-17 Wei Liu Water-stable photoluminescent semiconductor nanocrystal complexes and method of making same

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040115817A1 (en) * 2002-10-23 2004-06-17 Wei Liu Water-stable photoluminescent semiconductor nanocrystal complexes and method of making same

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ALIVISATOS PAUL: "The use of nanocrystals in biological detection.", NATURE BIOTECHNOLOGY, vol. 22, no. 1, January 2004 (2004-01-01), pages 47 - 52, XP002446195, ISSN: 1087-0156 *
DAHAN M ET AL: "TIME-GATED BIOLOGICAL IMAGING BY USE OF COLLOIDAL QUANTUM DOTS", OPTICS LETTERS, OSA, OPTICAL SOCIETY OF AMERICA, WASHINGTON, DC, US, vol. 26, no. 11, 1 June 2001 (2001-06-01), pages 825 - 827, XP001103014, ISSN: 0146-9592 *
LAKOWICZ JOSEPH R ET AL: "Time-resolved spectral observations of cadmium-enriched cadmium sulfide nanoparticles and the effects of DNA oligomer binding", ANALYTICAL BIOCHEMISTRY, vol. 280, no. 1, 10 April 2000 (2000-04-10), pages 128 - 136, XP002446376, ISSN: 0003-2697 *
See also references of WO2006014576A2 *
WU X ET AL: "IMMUNOFLUORESCENT LABELING OF CANCER MARKER HER2 AND OTHER CELLULAR TARGETS WITH SEMICONDUCTOR QUANTUM DOTS", NATURE BIOTECHNOLOGY, NATURE PUB. CO, NEW YORK, NY, US, vol. 21, January 2003 (2003-01-01), pages 41 - 46, XP008053284, ISSN: 1087-0156 *

Also Published As

Publication number Publication date
EP1784502A2 (en) 2007-05-16
CA2573150A1 (en) 2006-02-09

Similar Documents

Publication Publication Date Title
EP1731941A4 (en) Observing device and fluorescent light observing device
EP1817573A4 (en) Fluorescence detection
EP1674579A4 (en) Fluorescent probe
IL174379A0 (en) Fluorescence polarization imaging devices and methods
EP1659944A4 (en) Method for fluorescence lifetime imaging microscopy and spectroscopy
EP1788379A4 (en) Fluorescent microscope and fluorescent correlation spectral analysis device
EP1855102A4 (en) Fluorescence detecting device and fluorescence detecting method
EP1593091A4 (en) High contrast optoacoustical imaging using nanoparticles
GB0803596D0 (en) Fluorescent substance
GB2409036B (en) Analysis systems detecting particle size and fluorescence
EP1935958A4 (en) PHOSPHOR AND LUMINESCENT DEVICE USING THE SAME
GB0329849D0 (en) Fluorometers
GB0821526D0 (en) Lumen-traveling biological interface device
IL156556A0 (en) Life signs detector
DE602006015175D1 (en) FLUORESCENT AND MANUFACTURING METHOD THEREFOR
DE602006011168D1 (en) FLUORESCENT AND LIGHTING DEVICE
EP1785464A4 (en) FLUORESCENT AND LIGHT-EMITTING DEVICE, IMAGE DISPLAY AND LIGHTING DEVICE BASED ON IT
EP1571448A4 (en) FLUORESCENT INDICATOR USING FREIGHT
EP1731898A4 (en) FLUORESCENT PROBES
ZA200608959B (en) Immunoassay for plasmodium falciparum and assay device used therefor
EP1832875A4 (en) Biological microchip for multiple parallel immunoassay of compounds and immunoassay methods using said microchip
ZA200500238B (en) Fluorescent sensor.
EP1877425A4 (en) Fluorescent proteins and uses thereof
GB0507600D0 (en) Driving unit of fluorescent lamp and method for driving the same
EP1784502A4 (en) Fluorescent lifetime biological detection and imaging using water-stable semiconductor nanocrystals

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20070206

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

RIC1 Information provided on ipc code assigned before grant

Ipc: G01N 33/58 20060101AFI20070823BHEP

Ipc: G01N 21/64 20060101ALI20070823BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20070904

DAX Request for extension of the european patent (deleted)
17Q First examination report despatched

Effective date: 20071218

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20090730