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EP1931806A4 - Activation de la pkr par reaction en chaine d'hybridation - Google Patents

Activation de la pkr par reaction en chaine d'hybridation

Info

Publication number
EP1931806A4
EP1931806A4 EP06836249A EP06836249A EP1931806A4 EP 1931806 A4 EP1931806 A4 EP 1931806A4 EP 06836249 A EP06836249 A EP 06836249A EP 06836249 A EP06836249 A EP 06836249A EP 1931806 A4 EP1931806 A4 EP 1931806A4
Authority
EP
European Patent Office
Prior art keywords
pkr
activation
rna
hybridization chain
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP06836249A
Other languages
German (de)
English (en)
Other versions
EP1931806B1 (fr
EP1931806A2 (fr
Inventor
Robert Dirks
Niles A Pierce
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
California Institute of Technology
Original Assignee
California Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by California Institute of Technology filed Critical California Institute of Technology
Publication of EP1931806A2 publication Critical patent/EP1931806A2/fr
Publication of EP1931806A4 publication Critical patent/EP1931806A4/fr
Application granted granted Critical
Publication of EP1931806B1 publication Critical patent/EP1931806B1/fr
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
EP06836249A 2005-10-07 2006-10-06 Activation de la pkr par reaction en chaine d'hybridation Not-in-force EP1931806B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72501105P 2005-10-07 2005-10-07
PCT/US2006/039571 WO2007044727A2 (fr) 2005-10-07 2006-10-06 Activation de la pkr par reaction en chaine d'hybridation

Publications (3)

Publication Number Publication Date
EP1931806A2 EP1931806A2 (fr) 2008-06-18
EP1931806A4 true EP1931806A4 (fr) 2010-05-26
EP1931806B1 EP1931806B1 (fr) 2011-10-05

Family

ID=37943474

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06836249A Not-in-force EP1931806B1 (fr) 2005-10-07 2006-10-06 Activation de la pkr par reaction en chaine d'hybridation

Country Status (4)

Country Link
US (2) US7960357B2 (fr)
EP (1) EP1931806B1 (fr)
AT (1) ATE526975T1 (fr)
WO (1) WO2007044727A2 (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602005023426D1 (de) * 2004-03-25 2010-10-21 California Inst Of Techn Hybridisierungskettenreaktion
US7727721B2 (en) 2005-03-08 2010-06-01 California Institute Of Technology Hybridization chain reaction amplification for in situ imaging
WO2007044727A2 (fr) 2005-10-07 2007-04-19 California Institute Of Technology Activation de la pkr par reaction en chaine d'hybridation
US8778846B2 (en) * 2006-12-04 2014-07-15 General Electric Company Composition, device and associated method
US8318921B2 (en) 2007-03-01 2012-11-27 California Institute Of Technology Triggered RNAi
WO2008144562A1 (fr) 2007-05-16 2008-11-27 California Institute Of Technology Motif polyvalent d'acide nucléique en épingle à cheveux pour la programmation de voies d'auto-assemblage biomoléculaire
US8497364B2 (en) * 2008-02-27 2013-07-30 California Institute Of Technology Triggered RNAi
US20100021904A1 (en) * 2008-05-21 2010-01-28 Pierce Niles A Shielded cross-linking probes
US20100021901A1 (en) * 2008-05-22 2010-01-28 Peng Yin Compositions and methods for detecting analytes
US8241854B2 (en) * 2008-05-22 2012-08-14 California Institute Of Technology Triggered RNAi
JP5492901B2 (ja) * 2008-10-23 2014-05-14 コーニンクレッカ フィリップス エヌ ヴェ 分子イメージング
CN101756151B (zh) * 2008-12-24 2012-12-12 安琪酵母股份有限公司 一种高谷氨酸酵母抽提物及其制备方法
JP2009159990A (ja) * 2009-04-21 2009-07-23 Sanei Gen Ffi Inc 高栄養食
US8658780B2 (en) 2010-05-18 2014-02-25 California Institute Of Technology Triggered covalent probes for imaging and silencing genetic expression
US9834439B2 (en) 2010-07-20 2017-12-05 California Institute Of Technology Biomolecular self-assembly
US8877438B2 (en) 2010-07-20 2014-11-04 California Institute Of Technology Self-assembled polynucleotide structure
US8962241B2 (en) 2010-07-20 2015-02-24 California Institute Of Technology Triggered molecular geometry based bioimaging probes
DE102012203964B3 (de) * 2012-03-14 2013-02-28 GNA Biosolultions GmbH Verfahren und Kit zur Detektion von Nukleinsäuren
US9856472B2 (en) 2013-07-01 2018-01-02 California Institute Of Technology Small conditional RNAs
GB201401885D0 (en) 2014-02-04 2014-03-19 Olink Ab Proximity assay with detection based on hybridisation chain reaction (HCR)
EP3481843B1 (fr) 2016-07-05 2022-01-26 California Institute of Technology Réaction en chaîne d'hybridation d'initiateurs fractionnaire
CA3034617A1 (fr) 2016-08-30 2018-03-08 California Institute Of Technology Immunohistochimie par reaction en chaine d'hybridation
WO2018217905A1 (fr) * 2017-05-23 2018-11-29 Rutgers, The State University Of New Jersey Amplification de signaux in situ médiée par une cible avec des sondes en épingle à cheveux à double interaction
US12054711B2 (en) 2017-07-14 2024-08-06 City Of Hope Meta-stable oligonucleotides junctions for delivery of therapeutics
US12385041B2 (en) 2017-08-10 2025-08-12 City Of Hope Conditional-siRNAS and uses thereof in treating cardiac hypertrophy
CN110286216B (zh) * 2019-05-16 2021-10-15 中国科学院武汉物理与数学研究所 一种快速可视化的溶血性大肠杆菌o157：h7检测方法
US11873485B2 (en) 2021-01-26 2024-01-16 California Institute Of Technology Allosteric conditional guide RNAs for cell-selective regulation of CRISPR/Cas
CN117794550A (zh) * 2021-08-04 2024-03-29 国立大学法人东京大学 发夹核酸组合物
WO2024005045A1 (fr) * 2022-06-28 2024-01-04 国立大学法人東京大学 Composition d'acide nucléique en épingle à cheveux
WO2024166539A1 (fr) * 2023-02-07 2024-08-15 国立大学法人東京大学 Produit pharmaceutique d'assemblage d'acides nucléiques
AU2024242953A1 (en) 2023-04-04 2025-09-11 California Institute Of Technology Ultrasensitive molecular detection via hybridization chain reaction

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Also Published As

Publication number Publication date
US20110313030A1 (en) 2011-12-22
EP1931806B1 (fr) 2011-10-05
US8962582B2 (en) 2015-02-24
US20070087334A1 (en) 2007-04-19
EP1931806A2 (fr) 2008-06-18
ATE526975T1 (de) 2011-10-15
WO2007044727A3 (fr) 2009-05-28
US7960357B2 (en) 2011-06-14
WO2007044727A2 (fr) 2007-04-19

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