ES2059778T3 - Excipiente de liberacion sostenida directamente compresible. - Google Patents
Excipiente de liberacion sostenida directamente compresible.Info
- Publication number
- ES2059778T3 ES2059778T3 ES89309518T ES89309518T ES2059778T3 ES 2059778 T3 ES2059778 T3 ES 2059778T3 ES 89309518 T ES89309518 T ES 89309518T ES 89309518 T ES89309518 T ES 89309518T ES 2059778 T3 ES2059778 T3 ES 2059778T3
- Authority
- ES
- Spain
- Prior art keywords
- directly compressible
- sustained release
- release excipient
- excipient
- heteropolysaccharide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000546 pharmaceutical excipient Substances 0.000 title abstract 3
- 238000013268 sustained release Methods 0.000 title 1
- 239000012730 sustained-release form Substances 0.000 title 1
- 238000004132 cross linking Methods 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 230000003179 granulation Effects 0.000 abstract 1
- 238000005469 granulation Methods 0.000 abstract 1
- 239000003701 inert diluent Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 229940124531 pharmaceutical excipient Drugs 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
UNA GRANULACION COMPRESIBLE DIRECTAMENTE DE FLUJO LIBRE UTIL COMO EXCIPIENTE DE REPOSICION FARMACEUTICA LENTA ESTA DISPUESTA. EL EXCIPIENTE INCLUYE UNA MATRIZ HIDROFILICA QUE INCLUYE UN MATERIAL HETEROPLISACARIDO Y POLISACARIDO CAPAZ DE UNIR TRANSVERSALMENTE EL HETEROPOLISACARIDO Y UN DILUYENTE INERTE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/246,368 US4994276A (en) | 1988-09-19 | 1988-09-19 | Directly compressible sustained release excipient |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2059778T3 true ES2059778T3 (es) | 1994-11-16 |
| ES2059778T5 ES2059778T5 (es) | 2003-07-16 |
Family
ID=22930376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES89309518T Expired - Lifetime ES2059778T5 (es) | 1988-09-19 | 1989-09-19 | Excipiente de liberacion sostenida directamente compresible. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4994276A (es) |
| EP (1) | EP0360562B2 (es) |
| JP (1) | JPH0625073B2 (es) |
| AT (1) | ATE91887T1 (es) |
| AU (1) | AU623182B2 (es) |
| CA (1) | CA1339082C (es) |
| DE (1) | DE68907835T3 (es) |
| ES (1) | ES2059778T5 (es) |
| IE (1) | IE65170B1 (es) |
| WO (1) | WO1990003165A1 (es) |
Families Citing this family (103)
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| US6746691B2 (en) | 1993-09-20 | 2004-06-08 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics |
| US20060263428A1 (en) * | 1993-09-20 | 2006-11-23 | Eugenio Cefali | Methods for treating hyperlipidemia with intermediate release nicotinic acid compositions having unique biopharmaceutical characteristics |
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| JPS6124516A (ja) * | 1984-07-12 | 1986-02-03 | Fujisawa Pharmaceut Co Ltd | 持続性錠剤 |
| GB8426152D0 (en) * | 1984-10-16 | 1984-11-21 | Reckitt & Colmann Prod Ltd | Medicinal compositions |
| DE3440288C2 (de) * | 1984-11-05 | 1987-03-12 | Gergely, Gerhard, Dr.-Ing., Wien | Pharmazeutische Zubereitung mit einem Gehalt an Ibuprofen sowie Verfahren zu ihrer Herstellung |
| WO1987000044A1 (en) * | 1985-07-02 | 1987-01-15 | The Upjohn Company | Therapeutic formulations with bimodal release characteristics |
| GB8518927D0 (en) * | 1985-07-26 | 1985-09-04 | Vincent Processes Ltd | Tablets |
| GB8522453D0 (en) * | 1985-09-11 | 1985-10-16 | Lilly Industries Ltd | Chewable capsules |
| US4704285A (en) * | 1985-11-18 | 1987-11-03 | The Dow Chemical Company | Sustained release compositions comprising hydroxypropyl cellulose ethers |
| GB8601204D0 (en) * | 1986-01-18 | 1986-02-19 | Boots Co Plc | Therapeutic agents |
| IT1191674B (it) * | 1986-03-07 | 1988-03-23 | Eurand Spa | Formulazioni per la preparazione di farmaci a rilascio prolungato adatte alla somministrazione per via orale |
| US4855143A (en) * | 1986-04-04 | 1989-08-08 | Hans Lowey | Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics |
| GB8608818D0 (en) * | 1986-04-11 | 1986-05-14 | Reckitt & Colmann Prod Ltd | Pharmaceutical compositions |
| GB8613689D0 (en) * | 1986-06-05 | 1986-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| JPH0826346B2 (ja) * | 1986-07-10 | 1996-03-13 | 株式会社林原生物化学研究所 | 固状油溶性物質の製法 |
| US4792452A (en) * | 1987-07-28 | 1988-12-20 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
-
1988
- 1988-09-19 US US07/246,368 patent/US4994276A/en not_active Expired - Lifetime
-
1989
- 1989-09-14 JP JP1510135A patent/JPH0625073B2/ja not_active Expired - Lifetime
- 1989-09-14 AU AU43057/89A patent/AU623182B2/en not_active Expired
- 1989-09-14 WO PCT/US1989/003968 patent/WO1990003165A1/en unknown
- 1989-09-18 IE IE296889A patent/IE65170B1/en not_active IP Right Cessation
- 1989-09-18 CA CA000611700A patent/CA1339082C/en not_active Expired - Lifetime
- 1989-09-19 AT AT89309518T patent/ATE91887T1/de not_active IP Right Cessation
- 1989-09-19 ES ES89309518T patent/ES2059778T5/es not_active Expired - Lifetime
- 1989-09-19 DE DE68907835T patent/DE68907835T3/de not_active Expired - Lifetime
- 1989-09-19 EP EP89309518A patent/EP0360562B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATE91887T1 (de) | 1993-08-15 |
| AU4305789A (en) | 1990-04-18 |
| DE68907835T3 (de) | 2003-09-18 |
| EP0360562B1 (en) | 1993-07-28 |
| WO1990003165A1 (en) | 1990-04-05 |
| EP0360562B2 (en) | 2002-12-11 |
| US4994276A (en) | 1991-02-19 |
| JPH04501713A (ja) | 1992-03-26 |
| AU623182B2 (en) | 1992-05-07 |
| ES2059778T5 (es) | 2003-07-16 |
| CA1339082C (en) | 1997-07-29 |
| DE68907835D1 (de) | 1993-09-02 |
| IE892968L (en) | 1990-03-19 |
| DE68907835T2 (de) | 1993-11-11 |
| EP0360562A3 (en) | 1990-11-22 |
| EP0360562A2 (en) | 1990-03-28 |
| JPH0625073B2 (ja) | 1994-04-06 |
| IE65170B1 (en) | 1995-10-04 |
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