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ES2026826A6 - Procedimiento para la produccion de una vacuna subunidad contra el parvovirus canino y otros virus relacionados. - Google Patents

Procedimiento para la produccion de una vacuna subunidad contra el parvovirus canino y otros virus relacionados.

Info

Publication number
ES2026826A6
ES2026826A6 ES9100844A ES9100844A ES2026826A6 ES 2026826 A6 ES2026826 A6 ES 2026826A6 ES 9100844 A ES9100844 A ES 9100844A ES 9100844 A ES9100844 A ES 9100844A ES 2026826 A6 ES2026826 A6 ES 2026826A6
Authority
ES
Spain
Prior art keywords
cpv
protein
producing
related viruses
canine parvovirus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES9100844A
Other languages
English (en)
Inventor
De Turiso Sanchez Jose A Lopez
Caja Concepcion Martinez
Valdes Elena Cortes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inmunologia y Genetica Aplicada SA
Original Assignee
Ercros SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ercros SA filed Critical Ercros SA
Priority to ES9100844A priority Critical patent/ES2026826A6/es
Priority to PCT/ES1992/000031 priority patent/WO1992017205A1/es
Priority to DE69223939T priority patent/DE69223939T2/de
Priority to AU15850/92A priority patent/AU1585092A/en
Priority to DK92908548T priority patent/DK0554414T3/da
Priority to AT92908548T priority patent/ATE161729T1/de
Priority to EP92908548A priority patent/EP0554414B1/en
Publication of ES2026826A6 publication Critical patent/ES2026826A6/es
Priority to US08/317,785 priority patent/US5882652A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14311—Parvovirus, e.g. minute virus of mice
    • C12N2750/14322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/818—Viral vaccine for canidae or mustelidae, e.g. dogs, foxes, minks

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROCEDIMIENTO PARA LA PRODUCCION DE UNA VACUNA SUBUNIDAD CONTRA PARVOVIRUS CANINO (CPV) Y OTROS VIRUS RELACIONADOS (FPLV Y MEV). EL PROCEDIMIENTO COMPRENDE EN UNA PRIMERA ETAPA OBTENER UNA PROTEINA RECOMBINANTE VP2 DE CPV UTILIZANDO LA REPLICACION DE UN BACULOVIRUS RECOMBINANTE, DONDE HA SIDO PREVIAMENTE INSERTADO EL GEN CORRESPONDIENTE A LA VP2, EN CELULAS DE UN HUESPED PERMISIVO. LA PROTEINA VP2 OBTENIDA EN ESTA INVENCION TIENE LA CAPACIDAD DE FORMAR CAPSIDAS QUIMERICAS VACIAS CON ALTO PODER INMUNOGENICO POR LO QUE PUEDEN SER FORMULADAS EN VACUNAS PARA PROTEGER ANIMALES DE LA INFECCION CAUSADA POR CPV FPLV Y MEV. ADICIONALMENTE PUEDEN MANIPULARSE QUIMICA O GENETICAMENTE PARA INCORPORAR EPITOPOS CORRESPONDIENTES A OTRAS PROTEINAS VIRALES Y UTILIZARSE EN LA FORMULACION DE VACUNAS POLIVALENTES. EL BACULOVIRUS RECOMBINANTE ACMNPV.PCPVEX17 EXPRESA LA VP2 DE CPV EN CONDICIONES QUE LA POSIBILITAN PARA FORMAR CAPSIDAS PSEUDO-VIRALES Y HA SIDO DEPOSITADO EN LA ECACC. ESTAS VACUNAS TIENEN APLICACION A VETERINARIA.
ES9100844A 1991-03-26 1991-03-26 Procedimiento para la produccion de una vacuna subunidad contra el parvovirus canino y otros virus relacionados. Expired - Lifetime ES2026826A6 (es)

Priority Applications (8)

Application Number Priority Date Filing Date Title
ES9100844A ES2026826A6 (es) 1991-03-26 1991-03-26 Procedimiento para la produccion de una vacuna subunidad contra el parvovirus canino y otros virus relacionados.
PCT/ES1992/000031 WO1992017205A1 (es) 1991-03-26 1992-03-26 Procedimiento para la produccion de una vacuna subunidad contra el parvovirus canino y otros virus relacionados
DE69223939T DE69223939T2 (de) 1991-03-26 1992-03-26 Verfahren zur herstellung von untereinheitsimpfstoff gegen hundeparvovirus und verwandten viren
AU15850/92A AU1585092A (en) 1991-03-26 1992-03-26 Method for producing a subunit vaccine against the canine parvovirus and other related viruses
DK92908548T DK0554414T3 (da) 1991-03-26 1992-03-26 Fremgangsmåde til fremstilling af en underenhedsvaccine mod hundeparvovirus og andre beslægtede vira
AT92908548T ATE161729T1 (de) 1991-03-26 1992-03-26 Verfahren zur herstellung von untereinheitsimpfstoff gegen hundeparvovirus und verwandten viren
EP92908548A EP0554414B1 (en) 1991-03-26 1992-03-26 Method for producing a subunit vaccine against the canine parvovirus and other related viruses
US08/317,785 US5882652A (en) 1991-03-26 1994-10-04 Empty canine parvovirus capsids having CPV recombinant VP2 and vaccines having such capsids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9100844A ES2026826A6 (es) 1991-03-26 1991-03-26 Procedimiento para la produccion de una vacuna subunidad contra el parvovirus canino y otros virus relacionados.

Publications (1)

Publication Number Publication Date
ES2026826A6 true ES2026826A6 (es) 1992-05-01

Family

ID=8271929

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9100844A Expired - Lifetime ES2026826A6 (es) 1991-03-26 1991-03-26 Procedimiento para la produccion de una vacuna subunidad contra el parvovirus canino y otros virus relacionados.

Country Status (8)

Country Link
US (1) US5882652A (es)
EP (1) EP0554414B1 (es)
AT (1) ATE161729T1 (es)
AU (1) AU1585092A (es)
DE (1) DE69223939T2 (es)
DK (1) DK0554414T3 (es)
ES (1) ES2026826A6 (es)
WO (1) WO1992017205A1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2065254A1 (es) * 1993-01-23 1995-02-01 Inmunologia & Genetica Aplic Peptidos y vacunas sinteticas contra parvovirus canino y otros virus relacionados.

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US5814510A (en) * 1994-11-08 1998-09-29 Cornell Research Foundation, Inc. Attenuated canine parvovirus vaccine
US5885585A (en) * 1994-11-08 1999-03-23 Cornell Research Foundation, Inc. Attenuated canine parvovirus vaccine
CA2252375C (en) * 1996-04-19 2011-12-20 Colpan, Metin Nucleic acid vaccination for parvoviral infections
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WO1998025574A2 (en) * 1996-12-10 1998-06-18 Sloan-Kettering Institute For Cancer Research Stimulation of an immune response to differentiation antigen stimulated by altered antigen
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US8021666B2 (en) 1997-02-18 2011-09-20 Sloan-Kettering Institute For Cancer Research Method and compositions for stimulation of an immune response to CD20 using a xenogeneic CD20 antigen
CZ287956B6 (cs) * 1997-11-04 2001-03-14 Medipharm Cz, S. R. O. Perorální přípravek k prevenci a léčbě parvovirózy psů
US6759237B1 (en) 1998-11-05 2004-07-06 The Trustees Of The University Of Pennsylvania Adeno-associated virus serotype 1 nucleic acid sequences, vectors and host cells containing same
US6238860B1 (en) 1998-11-05 2001-05-29 Dyax Corp. Binding moieties for human parvovirus B19
DE69941905D1 (de) * 1998-11-10 2010-02-25 Univ North Carolina Virusvektoren und verfahren für ihre herstellung und verabreichung.
JP2003526377A (ja) * 2000-03-14 2003-09-09 ニユーロロジクス・インコーポレーテツド キメラキャプシドベクターの製造
EP1828390B1 (en) * 2004-12-15 2012-06-13 The University Of North Carolina At Chapel Hill Chimeric vectors
WO2007084773A2 (en) * 2006-01-20 2007-07-26 University Of North Carolina At Chapel Hill Enhanced production of infectious parvovirus vectors in insect cells
US8258274B2 (en) * 2007-06-14 2012-09-04 The Board Of Regents For Oklahoma State University Vaccines containing canine parvovirus genetic variants
US8227583B2 (en) 2007-06-14 2012-07-24 The Board Of Regents For Oklahoma State University Vaccines containing canine parvovirus genetic variants
CN102459578A (zh) * 2009-01-30 2012-05-16 俄克拉荷马州大学评议会 基于在北美狗中循环的犬瘟热病毒的免疫原性组合物、疫苗和诊断方法
WO2010093784A2 (en) 2009-02-11 2010-08-19 The University Of North Carolina At Chapel Hill Modified virus vectors and methods of making and using the same
CA2777692A1 (en) 2009-10-14 2011-04-21 Sanjay Kapil Isolation of a virus related to canine parvovirus-2 from a raccoon
EP2524037B1 (en) 2010-01-12 2018-05-16 The University Of North Carolina At Chapel Hill Restrictive inverted terminal repeats for viral vectors
WO2012109570A1 (en) 2011-02-10 2012-08-16 The University Of North Carolina At Chapel Hill Viral vectors with modified transduction profiles and methods of making and using the same
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WO2014143932A1 (en) 2013-03-15 2014-09-18 The University Of North Carolina At Chapel Hill Synthetic adeno-associated virus inverted terminal repeats
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EP3449250B1 (en) 2016-04-28 2020-11-04 Indiana University Research & Technology Corporation Methods and compositions for resolving components of a virus preparation
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WO2019060538A1 (en) 2017-09-20 2019-03-28 The Trustees Of Indiana University METHODS FOR LIPOPROTEIN RESOLUTION BY MASS SPECTROMETRY
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2065254A1 (es) * 1993-01-23 1995-02-01 Inmunologia & Genetica Aplic Peptidos y vacunas sinteticas contra parvovirus canino y otros virus relacionados.

Also Published As

Publication number Publication date
EP0554414A1 (en) 1993-08-11
ATE161729T1 (de) 1998-01-15
WO1992017205A1 (es) 1992-10-15
EP0554414B1 (en) 1998-01-07
AU1585092A (en) 1992-11-02
DE69223939D1 (de) 1998-02-12
DK0554414T3 (da) 1998-09-07
DE69223939T2 (de) 1998-07-09
US5882652A (en) 1999-03-16

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Effective date: 20141120