[go: up one dir, main page]

ES2173966T3 - Composiciones de esteroles a partir de jabon formado de la trituracion de pasta papelera. - Google Patents

Composiciones de esteroles a partir de jabon formado de la trituracion de pasta papelera.

Info

Publication number
ES2173966T3
ES2173966T3 ES95932593T ES95932593T ES2173966T3 ES 2173966 T3 ES2173966 T3 ES 2173966T3 ES 95932593 T ES95932593 T ES 95932593T ES 95932593 T ES95932593 T ES 95932593T ES 2173966 T3 ES2173966 T3 ES 2173966T3
Authority
ES
Spain
Prior art keywords
jabon
pasta
sterols
crushing
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95932593T
Other languages
English (en)
Other versions
ES2173966T5 (es
Inventor
Egon Novak
James P Kutney
Peter J Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of British Columbia
Original Assignee
University of British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23222178&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2173966(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by University of British Columbia filed Critical University of British Columbia
Publication of ES2173966T3 publication Critical patent/ES2173966T3/es
Application granted granted Critical
Publication of ES2173966T5 publication Critical patent/ES2173966T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • A23L33/11Plant sterols or derivatives thereof, e.g. phytosterols
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15Vitamins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nutrition Science (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Botany (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Fats And Perfumes (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Manufacture Of Tobacco Products (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

Uso de una composición que reduce el colesterol que comprende beta-sitosterol, campesterol y que comprende además estigmastanol, en la que el campesterol y el estigmastanol juntos comprenden al menos 50% de la concentración de beta-sitosterol y en el que la relación de beta-sitosterol es 1, 0, el campesterol está entre 0, 2 y 0, 4, y el estigmastanol está entre 0, 2 y 0, 5 en la fabricación de un medicamento para uso en un método de reducción de la concentración en plasma de colesterol lipoproteínico de baja densidad.
ES95932593T 1994-09-29 1995-09-29 Composiciones de esteroles a partir de jabon formado de la trituracion de pasta papelera. Expired - Lifetime ES2173966T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31494594A 1994-09-29 1994-09-29
US314945 1994-09-29

Publications (2)

Publication Number Publication Date
ES2173966T3 true ES2173966T3 (es) 2002-11-01
ES2173966T5 ES2173966T5 (es) 2008-01-16

Family

ID=23222178

Family Applications (2)

Application Number Title Priority Date Filing Date
ES05011507.0T Expired - Lifetime ES2464465T3 (es) 1994-09-29 1995-09-29 Composiciones de esteroles a partir de jabón de pulpa
ES95932593T Expired - Lifetime ES2173966T5 (es) 1994-09-29 1995-09-29 Composiciones de esteroles a partir de jabon formado de la trituracion de pasta papelera.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES05011507.0T Expired - Lifetime ES2464465T3 (es) 1994-09-29 1995-09-29 Composiciones de esteroles a partir de jabón de pulpa

Country Status (28)

Country Link
US (1) US5770749A (es)
EP (3) EP0783514B2 (es)
JP (1) JPH10506394A (es)
CN (1) CN1057768C (es)
AT (1) ATE216395T1 (es)
AU (1) AU3559795A (es)
BG (1) BG64054B1 (es)
BR (1) BR9509119A (es)
CA (1) CA2201328A1 (es)
CZ (1) CZ298622B6 (es)
DE (1) DE69526442T3 (es)
DK (2) DK0783514T4 (es)
EE (1) EE9700073A (es)
ES (2) ES2464465T3 (es)
GE (1) GEP20022657B (es)
HU (1) HUT77522A (es)
LT (1) LT4305B (es)
LV (1) LV11900B (es)
MD (1) MD1721C2 (es)
MX (1) MX9702308A (es)
NO (2) NO310293B1 (es)
NZ (1) NZ293210A (es)
PL (1) PL186441B1 (es)
PT (1) PT783514E (es)
RU (1) RU2165431C2 (es)
SK (1) SK284250B6 (es)
TJ (1) TJ302B (es)
WO (1) WO1996010033A1 (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965449A (en) * 1996-07-03 1999-10-12 Forbes Medi-Tech, Inc. Method of assessing risk for cardiovascular disease and other disorders and phytosterol-based compositions useful in preventing and treating cardiovascular disease and other disorders
US6139872A (en) * 1996-08-14 2000-10-31 Henkel Corporation Method of producing a vitamin product
US5985936A (en) * 1997-12-18 1999-11-16 Forbes Medi-Tech, Inc. Method of preventing and delaying onset of Alzheimer's disease and composition therefor
US5952393A (en) * 1998-02-12 1999-09-14 Sorkin, Jr.; Harlan Lee Composition for reducing serum cholesterol levels
US6110502A (en) * 1998-02-19 2000-08-29 Mcneil-Ppc, Inc. Method for producing water dispersible sterol formulations
JP2002517418A (ja) * 1998-06-05 2002-06-18 フォーブス メディ−テック インコーポレーテッド 高められた溶解性および分散性を有するフィトステロールおよび/またはフィトスタノ−ルよりなる組成物
AU4891699A (en) 1998-07-20 2000-02-14 Forbes Medi-Tech Inc. Compositions comprising phytosterol, phytostanol or mixtures of both and omega-3fatty acids or derivatives thereof and use of the composition in treating or preventing cardiovascular disease and other disorders
US6242001B1 (en) 1998-11-30 2001-06-05 Mcneil-Ppc, Inc. Method for producing dispersible sterol and stanol compounds
DE19916034C1 (de) * 1999-04-09 2000-08-03 Cognis Deutschland Gmbh Verfahren zur Gewinnung von Phytosterinen
JP2002543095A (ja) * 1999-04-27 2002-12-17 ステロール テクノロジース エルティディ. 抽出単離方法
JP2002543088A (ja) * 1999-04-27 2002-12-17 フォーブス メディ−テック インコーポレーテッド 木材または植物由来供給源からのフィトステロールの精製方法、およびそれから生じる組成物
US6770767B1 (en) * 1999-04-27 2004-08-03 Sterol Techologies Ltd. Method for the extraction and isolation of neutral substances from a soap
FI991533L (fi) * 1999-07-05 2001-01-06 Sohkar Oy Menetelmä orgaanisten aineiden käsittelemiseksi
WO2001015552A1 (en) * 1999-08-30 2001-03-08 Ocean Nutrition Canada Ltd. A nutritional supplement for lowering serum triglyceride and cholesterol levels
US6998501B1 (en) 1999-08-30 2006-02-14 Ocean Nutrition Canada Limited Nutritional supplement for lowering serum triglyceride and cholesterol levels
US6197832B1 (en) 1999-09-14 2001-03-06 Harlan Lee Sorkin, Jr. Composition for reducing serum cholesterol levels
US6355274B1 (en) 1999-12-15 2002-03-12 Mcneil-Ppc, Inc. Encapsulated long chain alcohols
NZ508692A (en) * 1999-12-15 2002-10-25 Mcneil Ppc Inc Cholesterol lowering comestibles comprising policosanol (predominately octasanol) and sterol
US7232574B1 (en) 1999-12-15 2007-06-19 Mcneil-Ppc, Inc. Long chain alcohols provided in edible oils
US7147859B2 (en) * 2000-05-15 2006-12-12 Laboratorios Biosintetica Ltda. Application of phytosterols (and their isomers), folic acid, cyanocobalamin and pyridoxin in dietetic (alimentary) fibers
BR0001794A (pt) * 2000-05-15 2001-12-26 Laboratorios Biosintetica Ltda Aplicação de fitosteróides (e seus isÈmeros), ácidofólico, cianocobalamina e piridoxina em fibrasdietéticas (alimentares)
WO2003009854A1 (en) * 2001-07-20 2003-02-06 Lonza Ag Lipid lowering composition comprising carnitine and phytosterol
WO2003075931A1 (en) * 2002-03-14 2003-09-18 Forbes Medi-Tech Inc. A method of treating diabetes mellitus including conditions associated with diabetes mellitus and complications of diabetes mellitus
US7368138B2 (en) * 2002-03-21 2008-05-06 Archer-Daniels-Midland Company Extraction of phytosterols from corn fiber using green solvents
CA2433246A1 (en) * 2003-06-25 2004-12-25 Telum Technologies Inc. Process for recovering value-added products from pulping soap
WO2007071036A1 (en) * 2005-12-20 2007-06-28 Forbes Medi-Tech Inc. Emulsions comprising non-esterified phytosterols in the aqueous phase
US8309156B2 (en) * 2005-12-20 2012-11-13 Pharmachem Laboratories, Inc. Compositions comprising one or more phytosterols and/or phytostanols, or derivatives thereof, and high HLB emulsifiers
US20070254026A1 (en) * 2006-05-01 2007-11-01 Forbes Medi-Tech Inc. Softgel capsules
WO2007124597A1 (en) * 2006-05-01 2007-11-08 Forbes Medi-Tech Inc. Composition comprising one or more esterified phytosterols and/or phytostanols into which are solubilized one or more unesterified phytosterols and/or phytostanols, in order to achieve therapeutic and formulation benefits
EP2036445A1 (en) * 2007-09-05 2009-03-18 Dietetics Pharma S.r.l. Nutraceutic preparation in powder form containing free plant sterols
US20110207952A1 (en) * 2010-02-22 2011-08-25 Rafael Avila Cholesterol extraction from algae and preparation of vegan vitamin d3
EA024619B1 (ru) * 2014-11-21 2016-10-31 Эльвин Гаджи оглы Керимли ФРАКСИНОСТЕРИН - 24β-ЭТИЛХОЛЕСТА-20-КАРБОКСИ-6(7),8(9)-ДИЕН 3β-ОЛА И ЕГО ПРОИЗВОДНОЕ
SE540791C2 (en) 2016-01-29 2018-11-13 Stora Enso Oyj Extraction of phytosterols
WO2017137908A1 (en) 2016-02-12 2017-08-17 Stora Enso Oyj Distillation of neutral compounds from tall oil soap

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2573891A (en) * 1950-05-09 1951-11-06 Pittsburgh Plate Glass Co Recovery of sterols
US2715638A (en) * 1953-07-28 1955-08-16 American Cyanamid Co Production of sterols from tall oil pitch
US2835682A (en) * 1955-08-08 1958-05-20 Swift & Co Sterol recovery process
US3840570A (en) * 1970-12-07 1974-10-08 Procter & Gamble Process for preparing sterols from tall oil pitch
SE417107B (sv) * 1973-06-29 1981-02-23 Bjarne Holmbom Forfarande for foredling av sapor
US4044031A (en) * 1976-07-02 1977-08-23 Ake Allan Johansson Process for the separation of sterols
US4208286A (en) 1977-11-03 1980-06-17 Kauppi Pekka K Sulphate soap skimming apparatus
US4153622A (en) * 1978-05-18 1979-05-08 Medipolar Oy Process for the recovery of β-sitosterol
FI58333C (fi) * 1978-10-27 1981-01-12 Kaukas Ab Oy Foerfarande foer framstaellning av under 5 vikt-% alfa2-sitosterol innehaollande beta-sitosterolkoncentrat
FI57956C (fi) * 1978-12-12 1980-11-10 Farmos Oy Foerfarande foer isolering av beta-sitosterol med laog alfa-sitosterolhalt
FI59416C (fi) * 1979-11-19 1981-08-10 Farmos Oy Foerfarande foer utvinning av beta-sitosterol ur en sterolblandning utvunnen fraon raosaopans neutralfraktion
FI63423C (fi) * 1981-01-27 1983-06-10 Farmos Oy Foerfarande foer separering av beta-sitosterol fraon en sterolblandning utvunnen ur raosaopans neutralfraktion
JPS57206336A (en) * 1981-06-12 1982-12-17 Ajinomoto Co Inc Edible oil
FI812279A7 (fi) 1981-07-21 1983-01-22 Kaukas Ab Oy Menetelmä sulfaattiselluloosaprosessin raakasuovan neutraliaineesta eristetyn -sitosterolin puhdistamiseksi.
FI65440C (fi) * 1981-07-21 1984-05-10 Kaukas Ab Oy Foerfarande foer separering av beta-sitosterol med en laog alfa-sitosterolhalt
JPS58116415A (ja) * 1981-12-28 1983-07-11 Riyoushiyoku Kenkyukai コレステロ−ル低下剤の使用方法
JPS6479119A (en) * 1987-09-22 1989-03-24 Daiichi Seiyaku Co Drug of blended two components
FR2653974B1 (fr) * 1989-11-03 1992-12-31 Expanchimie Sarl Additif alimentaire constitue d'extraits de soja et/ou d'avocat.
CA2028759A1 (en) 1989-11-22 1991-05-23 Jean-Marie Cassal Steroids
FI964951A0 (fi) * 1991-05-03 1996-12-11 Raision Tehtaat Oy Ab Seerumin korkean kolesterolitason alentamiseen käytettävä aine ja sen käyttö
US5286845A (en) 1992-05-20 1994-02-15 Union Camp Corporation Acidification of tall oil soap using carbon dioxide

Also Published As

Publication number Publication date
PL186441B1 (pl) 2004-01-30
RU2165431C2 (ru) 2001-04-20
EP1707572A3 (en) 2012-06-20
PT783514E (pt) 2002-09-30
WO1996010033A1 (en) 1996-04-04
BR9509119A (pt) 1997-10-28
DK0783514T4 (da) 2007-12-10
EP0783514B1 (en) 2002-04-17
PL319384A1 (en) 1997-08-04
EP1707572B1 (en) 2014-04-16
LT97074A (en) 1997-10-27
MD970178A (ro) 1999-02-28
MD1721B2 (en) 2001-08-31
CZ298622B6 (cs) 2007-11-28
LV11900A (lv) 1997-12-20
DK1707572T3 (da) 2014-05-12
CZ92797A3 (cs) 1998-02-18
LT4305B (lt) 1998-03-25
CN1166174A (zh) 1997-11-26
NO310293B1 (no) 2001-06-18
DE69526442T2 (de) 2002-11-21
US5770749A (en) 1998-06-23
EP1148062A3 (en) 2003-06-11
AU3559795A (en) 1996-04-19
MD1721C2 (ro) 2002-01-31
DE69526442D1 (de) 2002-05-23
NO971304D0 (no) 1997-03-20
DK0783514T3 (da) 2002-08-05
CA2201328A1 (en) 1996-04-04
NO971304L (no) 1997-05-14
BG101354A (en) 1998-03-31
EP1707572A2 (en) 2006-10-04
NO322293B1 (no) 2006-09-11
BG64054B1 (bg) 2003-11-28
EP0783514A1 (en) 1997-07-16
JPH10506394A (ja) 1998-06-23
ES2173966T5 (es) 2008-01-16
LV11900B (en) 1998-05-20
DE69526442T3 (de) 2007-10-31
EP1148062A2 (en) 2001-10-24
NO20011062D0 (no) 2001-03-01
GEP20022657B (en) 2002-03-25
ES2464465T3 (es) 2014-06-02
NZ293210A (en) 2000-03-27
MX9702308A (es) 1998-04-30
CN1057768C (zh) 2000-10-25
NO11062A (no) 1997-05-14
SK41597A3 (en) 1997-11-05
EE9700073A (et) 1997-10-15
ATE216395T1 (de) 2002-05-15
EP0783514B2 (en) 2007-08-01
HUT77522A (hu) 1998-05-28
SK284250B6 (sk) 2004-12-01
TJ302B (en) 2001-08-06

Similar Documents

Publication Publication Date Title
ES2173966T3 (es) Composiciones de esteroles a partir de jabon formado de la trituracion de pasta papelera.
Kovanen et al. Low density lipoprotein receptors in bovine adrenal cortex. I. Receptor-mediated uptake of low density lipoprotein and utilization of its cholesterol for steroid synthesis in cultured adrenocortical cells
ATE243498T1 (de) Aerosol formulierungen für buccale und pulmonale anwendung
CO4970835A1 (es) Inhibicion de la oxidacion de lipoproteinas
KR970706006A (ko) 폐 계면활성제와의 배합물 형태로 1종 이상의 글루코코르티코이드를 함유하는 irds 및 ards 치료용 조성물(compositions containing at least one glucocorticoid in combination with a pulmonary surfactant for the treatment of irds and ards)
BR9915008A (pt) Composição de xampu, e, processo para preparação da mesma
BR9917074A (pt) Composição cosmética ou famacêutica do tipoemulsão óleo-em-água que compreende um agentebiologicamente ativo micronizado e um sistemaemulsionante apropriado e processo detratamento cosmético
DE50011218D1 (de) Verwendung von nanoskaligen sterolen und sterolestern
BR0203902A (pt) Composições de compostos bioquìmicos envolvidos no metabolismo bioenergético das células e método de uso da mesma
ATE263578T1 (de) Feste arzneiformen, enthaltend clathrate vom steroidalen sexualhormon ethinylestradiol
AP2001002054A0 (en) Use of biogenic estrogen sulfamates for hormone replacement therapy.
FI971536A0 (fi) Keratinosyytti-kasvutekijän analogeja
Wiegratz et al. Effect of dienogest-containing oral contraceptives on lipid metabolism
Hofmann et al. Chenotherapy for gallstone dissolution: II. Induced changes in bile composition and gallstone response
CL2004000026A1 (es) Uso de una composicion que comprende 0 a alrededor de 29% de cis-clomifeno y de alrededor de 100 a alrededor de 71% de trans-clomifeno para preparar un medicamento util para aumentar los niveles de testosterona en suero en un mamifero masculino.
McCall et al. Psyllium husk I: effect on plasma lipoproteins, cholesterol metabolism, and atherosclerosis in African green monkeys
Inal et al. Effects of postmenopausal hormone replacement and α-tocopherol on the lipid profiles and antioxidant status
PT1135193E (pt) Agentes para o tratamento de tumores a base de lipossomas e compreendendo tamoxifeno
BR9814284A (pt) Composições e métodos para regulação de fagocitose e expressão de icam-1
ES2128710T3 (es) Liposomas que contienen proteinas encapsuladas, procedimiento para su produccion asi como las preparaciones farmaceuticas y cosmeticas que contienen estos liposomas.
Register et al. Effects of tibolone and conventional hormone replacement therapies on arterial and hepatic cholesterol accumulation and on circulating endothelin-1, vascular cell adhesion molecule-1, and E-selectin in surgically menopausal monkeys
ATE173624T1 (de) Synergistische pharmazeutische zusammensetungen, die triamcinolonacetonid und halcinonid enthalten
Erberich et al. Hormone replacement therapy in postmenopausal women and its effects on plasma lipid levels
KR890701091A (ko) 프레그네놀론 또는 프레그네놀론 에스테르를 함유하는 수화지질 층판상 또는 리포솜을 기제로 한 조성물 및 이러한 조성물이 들어있고 재생 혹은 생기회복 활성을 갖는 화장제 혹은 제약 조성물, 특히 피부과 조성물
Leuschner Ursodeoxycholic acid therapy in primary biliary cirrhosis

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 783514

Country of ref document: ES