[go: up one dir, main page]

FI974173L - Endoteliiniantagonisteja ja endoteliinisyntaasi-inhibiittoreita kohdunsupistussairauksien, raskausmyrkytyksen esivaiheen, valtimon haurausk ovetustaudin ja verenpainetaudin ennaltaehkäisemiseksi ja hoitamiseksi sekä hormonipalautusterapiaan - Google Patents

Endoteliiniantagonisteja ja endoteliinisyntaasi-inhibiittoreita kohdunsupistussairauksien, raskausmyrkytyksen esivaiheen, valtimon haurausk ovetustaudin ja verenpainetaudin ennaltaehkäisemiseksi ja hoitamiseksi sekä hormonipalautusterapiaan Download PDF

Info

Publication number
FI974173L
FI974173L FI974173A FI974173A FI974173L FI 974173 L FI974173 L FI 974173L FI 974173 A FI974173 A FI 974173A FI 974173 A FI974173 A FI 974173A FI 974173 L FI974173 L FI 974173L
Authority
FI
Finland
Prior art keywords
endothelin
preeclampsia
arteriosclerosis
hypertension
prevention
Prior art date
Application number
FI974173A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI974173A7 (fi
FI974173A0 (fi
Inventor
Kristof Chwalisz
Robert E Garfield
Original Assignee
Kristof Chwalisz
Robert E Garfield
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kristof Chwalisz, Robert E Garfield filed Critical Kristof Chwalisz
Publication of FI974173A0 publication Critical patent/FI974173A0/fi
Publication of FI974173A7 publication Critical patent/FI974173A7/fi
Publication of FI974173L publication Critical patent/FI974173L/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/223—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of alpha-aminoacids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
FI974173A 1995-05-08 1995-11-30 Endoteliiniantagonisteja ja endoteliinisyntaasi-inhibiittoreita kohdunsupistussairauksien, raskausmyrkytyksen esivaiheen, valtimon haurausk ovetustaudin ja verenpainetaudin ennaltaehkäisemiseksi ja hoitamiseksi sekä hormonipalautusterapiaan FI974173L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/437,462 US5811416A (en) 1994-06-06 1995-05-08 Endothelin antagonist and/or endothelin synthase inhibitor in combination with a progestin, an estrogen, a cyclooxygenase inhibitor, or a nitric acid donor or substrate
PCT/US1995/015220 WO1996035453A2 (fr) 1995-05-08 1995-11-30 Antagonistes de l'endotheline et inhibiteurs de l'endotheline-synthase pour la prevention et le traitement des troubles de la contractilite intra-uterine, de la preeclampsie, des maladies vasculaires atherosclereuses, de l'hypertension, ainsi que pour les hormonotherapies substitutives

Publications (3)

Publication Number Publication Date
FI974173A0 FI974173A0 (fi) 1997-11-07
FI974173A7 FI974173A7 (fi) 1998-01-07
FI974173L true FI974173L (fi) 1998-01-07

Family

ID=23736556

Family Applications (1)

Application Number Title Priority Date Filing Date
FI974173A FI974173L (fi) 1995-05-08 1995-11-30 Endoteliiniantagonisteja ja endoteliinisyntaasi-inhibiittoreita kohdunsupistussairauksien, raskausmyrkytyksen esivaiheen, valtimon haurausk ovetustaudin ja verenpainetaudin ennaltaehkäisemiseksi ja hoitamiseksi sekä hormonipalautusterapiaan

Country Status (7)

Country Link
US (1) US5811416A (fr)
EP (1) EP0844884A2 (fr)
AU (1) AU4243396A (fr)
CA (1) CA2220677A1 (fr)
FI (1) FI974173L (fr)
NO (1) NO975128L (fr)
WO (1) WO1996035453A2 (fr)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6210918B1 (en) * 1992-10-09 2001-04-03 The Regents Of The University Of California Non-invasive method for detection, diagnosis or prediction of term or pre-term labor
US6407082B1 (en) * 1996-09-13 2002-06-18 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a vitamin D compound
US6743783B1 (en) * 1993-12-01 2004-06-01 Marine Polymer Technologies, Inc. Pharmaceutical compositions comprising poly-β-1→4-N-acetylglucosamine
US6620590B2 (en) 1996-07-11 2003-09-16 Isis Innovation Limited Diagnosis of pre-eclampsia
US6511970B1 (en) 1996-09-13 2003-01-28 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium
US6034074A (en) 1996-09-13 2000-03-07 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a Vitamin D compound
US6028064A (en) 1996-09-13 2000-02-22 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of progestin products
US6765002B2 (en) 2000-03-21 2004-07-20 Gustavo Rodriguez Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium
DE19652374A1 (de) * 1996-12-04 1998-06-10 Schering Ag Verwendung von Endothelin-Konjugaten in der Therapie, neue Endothelin-Konjugate, diese enthaltende Mittel, sowie Verfahren zu deren Herstellung
ATE228011T1 (de) * 1998-08-06 2002-12-15 Vascular Biotech Gmbh Wirkstoffkombination insbesondere zur prophylaxe und therapie von ischämischen organschäden und reperfusionssyndromen
CA2367002A1 (fr) * 1999-03-19 2000-09-28 Michael A. Moskowitz Renforcement de la biodisponibilite des medicaments dans le cerveau
US20010044431A1 (en) * 2000-03-21 2001-11-22 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US6642055B1 (en) 2000-03-31 2003-11-04 Arbogast Pharmaceuticals, Inc. Method for the prediction of preeclampsia and other diseases
EP1363669A2 (fr) * 2001-02-02 2003-11-26 Pharmacia Corporation Methode d'utilisation d'un inhibiteur de la cyclooxygenase-2 et de steroides sexuels dans une polytherapie pour traiter et prevenir la dysmenorrhee
AUPR516901A0 (en) 2001-05-22 2001-06-14 Occupational & Medical Innovations Ltd Improvements to a single use syringe
US8563592B2 (en) 2001-11-01 2013-10-22 Spectrum Pharmaceuticals, Inc. Bladder cancer treatment and methods
PT2060259E (pt) 2001-11-01 2010-04-26 Spectrum Pharmaceuticals Inc Composições médicas para o tratamento intravesical do cancro da bexiga
RU2208438C1 (ru) * 2001-12-24 2003-07-20 Биологический факультет Московского государственного университета им. М.В. Ломоносова Донор оксида азота, активирующий растворимую форму гуанилатциклазы, ингибирующий агрегацию тромбоцитов и обладающий спазмолитическим и сосудорасширяющим действием
US7351692B2 (en) * 2002-06-19 2008-04-01 The Board Of Trustees Of The University Of Illinois Method and composition for potentiating the antipyretic action of a nonopioid analgesic
AU2003270446A1 (en) * 2002-09-25 2004-04-19 The Board Of Trustees Of The University Of Illinois Method and composition for treating alzheimer's disease and dementias of vascular origin
US8026216B2 (en) * 2002-10-24 2011-09-27 Spectrum Pharmaceuticals, Inc. Methods and compositions for contributing to the treatment of cancers
US20080145424A1 (en) * 2002-10-24 2008-06-19 Enos Phramaceuticals, Inc. Sustained release L-arginine formulations and methods of manufacture and use
US20070032422A1 (en) * 2002-10-24 2007-02-08 Spectrum Pharmaceuticals, Inc. Methods, compositions and articles of manufacture for contributing to the treatment of cancers
EP1556073B1 (fr) * 2002-10-24 2016-01-06 The Board Of Trustees Of The University Of Illinois Methode et composition destinees a la prevention de l'apparition et au traitement de tumeurs solides
EP1562555A2 (fr) * 2002-10-24 2005-08-17 Enos Pharmaceuticals, Inc. Preparations de l-arginine a liberation prolongee et procedes de fabrication et d'utilisation de celles-ci
US8217010B2 (en) 2002-10-24 2012-07-10 The Board Of Trustees Of The University Of Illinois Methods, compositions and articles of manufacture for contributing to the treatment of solid tumors
GB0308967D0 (en) * 2003-04-17 2003-05-28 Univ London Screen for pre-eclampsia
PL1624878T3 (pl) * 2003-05-22 2007-01-31 Pantarhei Bioscience Bv Zastosowanie kompozycji zawierającej estrogenowy składnik w celu leczenia i zapobiegania bólowi mięśniowo-szkieletowemu
WO2005023189A2 (fr) * 2003-09-03 2005-03-17 Pharmacia Corporation Procede de prevention ou de traitement de la douleur, de l'inflammation, et de troubles lies a l'inflammation avec un inhibiteur selectif de cox-2 en combinaison avec un agent donneur de monoxyde d'azote et compositions en contenant
EP1675619A4 (fr) * 2003-09-29 2010-10-06 Palmetto Pharmaceuticals Llc Formulations de l'arginine a liberation prolongee, procedes de fabrication et utilisations
CA2615393C (fr) * 2005-07-19 2011-09-20 The Population Council, Inc. Methodes et compositions pour contraception d'urgence faisant intervenir des antagonistes du recepteur de l'endotheline
WO2007054975A1 (fr) * 2005-11-08 2007-05-18 Panacea Biotec Ltd Compositions pharmaceutiques destinees au traitement de troubles cardiovasculaires et d'autres troubles associes
WO2007092963A1 (fr) * 2006-02-09 2007-08-16 Spectrum Pharmaceuticals, Inc. Traitement du cancer de la vessie et procedes correspondants
RU2009111605A (ru) * 2006-08-31 2010-10-10 Спектрум Фармасьютикалз, Инк. (Us) Сенсибилизация опухолевых клеток к лучевой терапии посредством введения агонистов эндотелина
ES2918452T3 (es) * 2007-02-19 2022-07-15 Marine Polymer Tech Inc Composiciones hemostáticas y regímenes terapéuticos
US8858964B2 (en) 2010-04-15 2014-10-14 Marine Polymer Technologies, Inc. Anti-bacterial applications of poly-N-acetylglucosamine nanofibers
AU2012242479B2 (en) 2011-04-15 2015-04-16 Marine Polymer Technologies, Inc. Treatment of disease with poly-n-acetylglucosamine nanofibers
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
CA2856520C (fr) 2011-11-23 2021-04-06 Therapeuticsmd, Inc. Preparations et therapies de substitution pour hormonotherapie naturelle combinee
US9308235B2 (en) 2012-05-09 2016-04-12 Spectrum Pharmaceuticals, Inc. Treatment of primary and metastatic carcinoma
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
AU2015264003A1 (en) 2014-05-22 2016-11-17 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
MX2016013693A (es) 2014-07-29 2017-10-31 Therapeuticsmd Inc Crema transdermica.
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
JP2019513709A (ja) 2016-04-01 2019-05-30 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． ステロイドホルモン薬学的組成物
WO2017173044A1 (fr) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Compositions d'hormones stéroïdes dans des huiles à chaîne moyenne
WO2017218418A1 (fr) * 2016-06-13 2017-12-21 The Board Of Regents Of The University Of Texas System Compositions et procédés de modélisation de l'insuffisance cardiaque à fraction d'éjection conservée
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260276A (en) * 1991-06-14 1993-11-09 Warner-Lambert Company Linear and monocyclic endothelin antagonists
GB9123967D0 (en) * 1991-11-12 1992-01-02 Fujisawa Pharmaceutical Co New compound and its preparation
US5378715A (en) * 1992-02-24 1995-01-03 Bristol-Myers Squibb Co. Sulfonamide endothelin antagonists
WO1993025580A1 (fr) * 1992-06-18 1993-12-23 Immunopharmaceutics, Inc. Peptides cycliques modulant l'activite de l'endotheline
US5508045A (en) * 1992-10-09 1996-04-16 The Regents Of The University Of California Method and agents for control and management of labor during pregnancy
GB9313330D0 (en) * 1993-06-28 1993-08-11 Fujisawa Pharmaceutical Co New compound and its preparation
US5895783A (en) * 1993-07-16 1999-04-20 Schering Aktiengesellschaft Treatment of preeclampsia and preterm labor with combination of progestational agent and a nitric oxide synthase substrate and/or donor
AU8144594A (en) * 1993-11-16 1995-06-06 Robert E Garfield Treatment of uterine contractility disorders with a nitric oxide synthase substrate and/or donor, or a nitric oxide inhibitor

Also Published As

Publication number Publication date
FI974173A7 (fi) 1998-01-07
FI974173A0 (fi) 1997-11-07
WO1996035453A3 (fr) 1997-03-13
US5811416A (en) 1998-09-22
EP0844884A2 (fr) 1998-06-03
NO975128D0 (no) 1997-11-07
NO975128L (no) 1998-01-07
CA2220677A1 (fr) 1996-11-14
WO1996035453A2 (fr) 1996-11-14
AU4243396A (en) 1996-11-29

Similar Documents

Publication Publication Date Title
FI974173L (fi) Endoteliiniantagonisteja ja endoteliinisyntaasi-inhibiittoreita kohdunsupistussairauksien, raskausmyrkytyksen esivaiheen, valtimon haurausk ovetustaudin ja verenpainetaudin ennaltaehkäisemiseksi ja hoitamiseksi sekä hormonipalautusterapiaan
NO20040936L (no) Plaster for behandling av dysfunksjoner og forstyrrelser ved neglevekst.
NO20001754D0 (no) Prostaglandinagonister og anvendelse derav for behandling av benforstyrrelser
HUP9803018A3 (en) Use of cyclooxygenase-2 inhibitors for producing pharmaceutical compositions suitable for the treatment and prevention of tumors, tumor-veloted disorders and cachexia
NO972972L (no) Sammensetninger for behandling av dermatologiske forstyrrelser og metoder for deres anvendelse
HUP0103856A3 (en) Pharmaceutical composition for the treatment of acute disorders
NO20000688D0 (no) Anvendelse av lokalt avleverte metallioner for behandling av periodontal sykdom
EE200100659A (et) Diaminotiasoolid ja nende kasutamine proteiinikinaaside pärssimiseks
IL134013A (en) Substituted quinazoline derivatives and their use as tyrosine kinase inhibitors
AU4060599A (en) Pharmaceutical composition for treating or preventing sleep disorders
IL138129A (en) Composition for therapy of estrogen-associated disorders
AU2003216586A8 (en) Diaryl pyrimidinone derivatives useful for the treatment of inflammation and immunogolical diseases
AP2000001796A0 (en) The use of inhibitors of the renin-angiotensin system for the treatment of hypoxia or impaired metabolic function
IL127496A0 (en) The use of MMP inhibitors for the treatment of ocular angiogenesis
PL350167A1 (en) Medicament for treating hypertension
PL373835A1 (en) Use of cd23 antagonists for the treatment of neoplastic disorders
DE69432595D1 (de) Antagonisten des angiotensin ii-rezeptors zur behandlung von chronischen entzündlichen erkrankungen
DK1041985T3 (da) Kombination af benzocycloheptapyridinforbindelser og antineoplastiske lægemidler til behandling af profilerative sygdomme
PT983275E (pt) Novos derivados do triptolido vantajosos para o tratamento de doencas autoimunes
HUP0000935A3 (en) Atropisomers of 3-heteroaryl-4(3h)-quinazolinones and their use for the treatment of neurodegenerative and cns-trauma related conditions
NO971449D0 (no) Nye hormonelle medikamenter og anvendelse derav for korrigering av östrogen-mangel
ID27214A (id) Triazolopiridina untuk pengobatan gangguan trombosis
AU7788500A (en) Use of substance p antagonists for influencing the circadian timing system
FR2761058B1 (fr) Composition et procede pour la stimulation de la germination des grains de pollen
NO982112L (no) Blanding med bestemt dose, av en angiotensinkonverterende enzyminhibitor og en kalsiumkanal antagonist, fremgangsmÕte for fremstilling og anvendelse derav i behandling av kardiovaskulµre sykdommer