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FR2672617B1 - Sequences nucleotidiques codant pour des regions variables de chaines beta des recepteurs des lymphocytes t humains, segments peptidiques correspondants et les applications diagnostiques et therapeutiques. - Google Patents

Sequences nucleotidiques codant pour des regions variables de chaines beta des recepteurs des lymphocytes t humains, segments peptidiques correspondants et les applications diagnostiques et therapeutiques.

Info

Publication number
FR2672617B1
FR2672617B1 FR9101613A FR9101613A FR2672617B1 FR 2672617 B1 FR2672617 B1 FR 2672617B1 FR 9101613 A FR9101613 A FR 9101613A FR 9101613 A FR9101613 A FR 9101613A FR 2672617 B1 FR2672617 B1 FR 2672617B1
Authority
FR
France
Prior art keywords
diagnostic
human
nucleotide sequences
sequences encoding
variable regions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9101613A
Other languages
English (en)
Other versions
FR2672617A1 (fr
Inventor
Thierry Hercend
Frederic Triebel
Sergio Roman-Roman
Laurent Ferradini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9101613A priority Critical patent/FR2672617B1/fr
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to JP4506380A priority patent/JPH06502997A/ja
Priority to EP92906703A priority patent/EP0528007A1/fr
Priority to PCT/FR1992/000130 priority patent/WO1992013950A2/fr
Priority to AU15445/92A priority patent/AU660306B2/en
Priority to ZA921014A priority patent/ZA921014B/xx
Priority to CA002079881A priority patent/CA2079881C/fr
Priority to IE044792A priority patent/IE920447A1/en
Priority to KR1019920702512A priority patent/KR100227303B1/ko
Publication of FR2672617A1 publication Critical patent/FR2672617A1/fr
Application granted granted Critical
Publication of FR2672617B1 publication Critical patent/FR2672617B1/fr
Priority to US08/423,383 priority patent/US5700907A/en
Priority to US08/437,353 priority patent/US5830758A/en
Priority to KR1019997004635A priority patent/KR100297082B1/ko
Priority to US10/095,672 priority patent/US7294712B2/en
Priority to US11/867,862 priority patent/US8709426B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
FR9101613A 1990-06-04 1991-02-12 Sequences nucleotidiques codant pour des regions variables de chaines beta des recepteurs des lymphocytes t humains, segments peptidiques correspondants et les applications diagnostiques et therapeutiques. Expired - Lifetime FR2672617B1 (fr)

Priority Applications (14)

Application Number Priority Date Filing Date Title
FR9101613A FR2672617B1 (fr) 1991-02-12 1991-02-12 Sequences nucleotidiques codant pour des regions variables de chaines beta des recepteurs des lymphocytes t humains, segments peptidiques correspondants et les applications diagnostiques et therapeutiques.
KR1019920702512A KR100227303B1 (ko) 1991-02-12 1992-02-12 인체 t 임파구 수용체의 베타 사슬의 가변성 영역을 코딩하는 뉴클레오티드 서열, 대응하는 펩티드 세그먼트 및 진단 및 치료 용도
EP92906703A EP0528007A1 (fr) 1991-02-12 1992-02-12 SEQUENCES NUCLEOTIDIQUES CODANT POUR DES REGIONS VARIABLES DE CHAINES $g(b) DES RECEPTEURS DES LYMPHOCYTES T HUMAINS, SEGMENTS PEPTIDIQUES CORRESPONDANTS ET LES APPLICATIONS DIAGNOSTIQUES ET THERAPEUTIQUES
PCT/FR1992/000130 WO1992013950A2 (fr) 1991-02-12 1992-02-12 SEQUENCES NUCLEOTIDIQUES CODANT POUR DES REGIONS VARIABLES DE CHAINES β DES RECEPTEURS DES LYMPHOCYTES T HUMAINS, SEGMENTS PEPTIDIQUES CORRESPONDANTS ET LES APPLICATIONS DIAGNOSTIQUES ET THERAPEUTIQUES
AU15445/92A AU660306B2 (en) 1991-02-12 1992-02-12 Nucleotidic sequences coding for variable regions of beta chains of human T lymphocyte receptors, corresponding peptidic segments and diagnostic and therapeutic applications
ZA921014A ZA921014B (en) 1991-02-12 1992-02-12 Nucleotide sequences coding for beta-chain variable regions of human t-lymphocyte receptors,corresponding peptide segments and diagnostic and therapeutic applications
CA002079881A CA2079881C (fr) 1991-02-12 1992-02-12 Sequences nucleotidiques codant pour des regions variables de chaines .beta. des recepteurs des lymphocytes t humains, segments peptidiques correspondants et les applications diagnostiques et therapeutiques
IE044792A IE920447A1 (en) 1991-02-12 1992-02-12 NUCLEOTIDE SEQUENCES CODING FOR ß-CHAIN VARIABLE REGIONS OF¹HUMAN T-LYMPHOCYTE RECEPTORS, CORRESPONDING PEPTIDE SEGMENTS¹AND DIAGNOSTIC AND THERAPEUTIC APPLICATIONS
JP4506380A JPH06502997A (ja) 1991-02-12 1992-02-12 ヒトＴリンパ球レセプターのβ鎖の可変領域をコードするヌクレオチド配列対応するペプチドセグメント並びに診断及び治療への利用
US08/423,383 US5700907A (en) 1991-02-12 1995-04-14 Nucleotide sequences coding for variable regions of β chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses
US08/437,353 US5830758A (en) 1991-02-12 1995-05-09 Isolated Vβ TCR antibodies
KR1019997004635A KR100297082B1 (ko) 1991-02-12 1999-05-26 인체 Ｔ 임파구 수용체의 β 사슬의 가변성 영역을 코딩하는 뉴클레오티드 서열, 대응하는 펩티드 세그먼트 및 진단 및 치료 용도
US10/095,672 US7294712B2 (en) 1990-06-04 2002-03-12 Nucleotide sequences coding for variable regions of β chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses
US11/867,862 US8709426B2 (en) 1991-02-12 2007-10-05 Nucleotide sequence coding for variable regions of β chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9101613A FR2672617B1 (fr) 1991-02-12 1991-02-12 Sequences nucleotidiques codant pour des regions variables de chaines beta des recepteurs des lymphocytes t humains, segments peptidiques correspondants et les applications diagnostiques et therapeutiques.

Publications (2)

Publication Number Publication Date
FR2672617A1 FR2672617A1 (fr) 1992-08-14
FR2672617B1 true FR2672617B1 (fr) 1994-09-23

Family

ID=9409619

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9101613A Expired - Lifetime FR2672617B1 (fr) 1990-06-04 1991-02-12 Sequences nucleotidiques codant pour des regions variables de chaines beta des recepteurs des lymphocytes t humains, segments peptidiques correspondants et les applications diagnostiques et therapeutiques.

Country Status (2)

Country Link
FR (1) FR2672617B1 (fr)
ZA (1) ZA921014B (fr)

Also Published As

Publication number Publication date
FR2672617A1 (fr) 1992-08-14
ZA921014B (en) 1993-04-28

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