GB796498A - Dental compositions - Google Patents
Dental compositionsInfo
- Publication number
- GB796498A GB796498A GB36063/54A GB3606354A GB796498A GB 796498 A GB796498 A GB 796498A GB 36063/54 A GB36063/54 A GB 36063/54A GB 3606354 A GB3606354 A GB 3606354A GB 796498 A GB796498 A GB 796498A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pregnene
- dione
- triol
- hydrocortisone
- per cent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- JYGXADMDTFJGBT-VWUMJDOOSA-N Hydrocortisone Natural products O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 abstract 11
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
- 229960000890 hydrocortisone Drugs 0.000 abstract 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 abstract 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- -1 hydrocortisone aldehyde Chemical class 0.000 abstract 2
- 239000002674 ointment Substances 0.000 abstract 2
- SUPOKHOQAKXOHJ-BYZMTCBYSA-N (8s,9s,10r,13r,14s,17s)-17-ethyl-10,13-dimethyl-2,3,6,7,8,9,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthrene Chemical compound C1CC2=CCCC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](CC)[C@@]1(C)CC2 SUPOKHOQAKXOHJ-BYZMTCBYSA-N 0.000 abstract 1
- 241000416162 Astragalus gummifer Species 0.000 abstract 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 abstract 1
- 235000019739 Dicalciumphosphate Nutrition 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 229920000569 Gum karaya Polymers 0.000 abstract 1
- 239000004264 Petrolatum Substances 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 241000934878 Sterculia Species 0.000 abstract 1
- 229920001615 Tragacanth Polymers 0.000 abstract 1
- 239000000853 adhesive Substances 0.000 abstract 1
- 230000001070 adhesive effect Effects 0.000 abstract 1
- 229910000019 calcium carbonate Inorganic materials 0.000 abstract 1
- 229960003563 calcium carbonate Drugs 0.000 abstract 1
- 235000010216 calcium carbonate Nutrition 0.000 abstract 1
- 239000001506 calcium phosphate Substances 0.000 abstract 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 abstract 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 abstract 1
- 229940105329 carboxymethylcellulose Drugs 0.000 abstract 1
- ALEXXDVDDISNDU-JZYPGELDSA-N cortisol 21-acetate Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)COC(=O)C)(O)[C@@]1(C)C[C@@H]2O ALEXXDVDDISNDU-JZYPGELDSA-N 0.000 abstract 1
- 239000000001 dental powder Substances 0.000 abstract 1
- NEFBYIFKOOEVPA-UHFFFAOYSA-K dicalcium phosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])([O-])=O NEFBYIFKOOEVPA-UHFFFAOYSA-K 0.000 abstract 1
- 229940038472 dicalcium phosphate Drugs 0.000 abstract 1
- 229910000390 dicalcium phosphate Inorganic materials 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- 235000019441 ethanol Nutrition 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 abstract 1
- 235000013355 food flavoring agent Nutrition 0.000 abstract 1
- 235000011187 glycerol Nutrition 0.000 abstract 1
- 229960005150 glycerol Drugs 0.000 abstract 1
- 229960001067 hydrocortisone acetate Drugs 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 235000010494 karaya gum Nutrition 0.000 abstract 1
- 239000000231 karaya gum Substances 0.000 abstract 1
- 229940039371 karaya gum Drugs 0.000 abstract 1
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 abstract 1
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 abstract 1
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 abstract 1
- 229960002216 methylparaben Drugs 0.000 abstract 1
- 239000002480 mineral oil Substances 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 229940066842 petrolatum Drugs 0.000 abstract 1
- 235000019271 petrolatum Nutrition 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 229960004063 propylene glycol Drugs 0.000 abstract 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 abstract 1
- 229940081974 saccharin Drugs 0.000 abstract 1
- 235000019204 saccharin Nutrition 0.000 abstract 1
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 abstract 1
- 239000000344 soap Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- 239000000606 toothpaste Substances 0.000 abstract 1
- 229940034610 toothpaste Drugs 0.000 abstract 1
- 235000010487 tragacanth Nutrition 0.000 abstract 1
- 239000000196 tragacanth Substances 0.000 abstract 1
- 229940116362 tragacanth Drugs 0.000 abstract 1
- 229940045860 white wax Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/60—Preparations for dentistry comprising organic or organo-metallic additives
- A61K6/69—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Cosmetics (AREA)
Abstract
A dental composition comprises a carrier which is an ointment suitable for application to the gingival tissues, toothpaste, dental powders, or a denture adhesive, and a D 4-pregnene-11b , 17a -diol-3,20-dione having at least one of the hydrogen atoms at the 21 position replaced by an hydroxy, oxo or ester group. The active ingredient may be present from 0.05 to 25 per cent by weight of the composition but it is preferred that ointments should contain from 1 to 2.5 per cent and the other forms from 0.1 to 0.5 per cent by weight. Specified active ingredients are hydrocortisone aldehyde (D 4-pregnene - 11b ,17a - diol - 21 - al - 3,20 - dione), hydrocortisone (D 4 - pregnene - 11b ,17a ,21 - triol - 3,20 - dione), hydrocortisone alkanoates such as hydrocortisone acetate (D 4-pregnene-11b ,17a ,21 - triol - 3,20 - dione - 21 - acetate) and D 4 - pregnene - 11b ,17a ,21 - triol - 3,20 - dione - 21 - tertiary butyl acetate, D 4 - pregnene - 11b ,17a ,21 - triol - 3,20 - dione - 21 - propionate, D 4 - pregnene - 11b ,17a ,21 - triol - 3,20 - dione - 21 - benzoate, D 4 - pregnene-11b ,17a ,21 - triol - 3,20 - dione - 21 - tricarballylate. Substances which may comprise the carrier are polyethylene glycol, propylene glycol, white wax, petrolatum karaya gum, tragacanth, carboxymethylcellulose, glycerine, mineral oils, soaps, calcium carbonate, dicalcium phosphate, saccharin, methyl parahydroxybenzoate, alcohol, surface-active and flavouring agents.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US796498XA | 1954-01-13 | 1954-01-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB796498A true GB796498A (en) | 1958-06-11 |
Family
ID=22151905
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB36063/54A Expired GB796498A (en) | 1954-01-13 | 1954-12-13 | Dental compositions |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB796498A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6290975B1 (en) | 1998-05-15 | 2001-09-18 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Method for the prevention of gum disease |
| ITMI20130723A1 (en) * | 2013-05-03 | 2014-11-04 | Betafarma S P A | COMPOSITION OF ADHESIVE PASTE FOR DENTAL PROSTHESES AND ITS PRODUCTION METHOD. |
-
1954
- 1954-12-13 GB GB36063/54A patent/GB796498A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6290975B1 (en) | 1998-05-15 | 2001-09-18 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Method for the prevention of gum disease |
| ITMI20130723A1 (en) * | 2013-05-03 | 2014-11-04 | Betafarma S P A | COMPOSITION OF ADHESIVE PASTE FOR DENTAL PROSTHESES AND ITS PRODUCTION METHOD. |
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