HRP20110825T1 - Derivati aminotriazola kao alx agonisti - Google Patents

Derivati aminotriazola kao alx agonisti Download PDF

Info

Publication number: HRP20110825T1
Authority: HR; Croatia
Prior art keywords: triazol; acetyl; ylmethyl; phenyl; amide
Prior art date: 2007-12-18

Application number

HR20110825T

Other languages

English (en)

Croatian (hr)

Inventor

Bur Daniel

Corminboeuf Olivier

Cren Sylvaine

Grisostomi Corinna

Leroy Xavier

Richard-Bildstein Sylvia

Original Assignee

Actelion Pharmaceuticals Ltd.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-12-18

Filing date

2008-12-17

Publication date

2011-12-31

2008-12-17 Application filed by Actelion Pharmaceuticals Ltd. filed Critical Actelion Pharmaceuticals Ltd.

2011-12-31 Publication of HRP20110825T1 publication Critical patent/HRP20110825T1/hr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pulmonology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Virology (AREA)
Molecular Biology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
AIDS & HIV (AREA)
Rheumatology (AREA)
Tropical Medicine & Parasitology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

HR20110825T 2007-12-18 2008-12-17 Derivati aminotriazola kao alx agonisti HRP20110825T1 (hr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
IB2007055199		2007-12-18
IB2008054369		2008-10-23
PCT/IB2008/055375 WO2009077990A1 (fr)	2007-12-18	2008-12-17	Dérivés d'aminotriazole comme agonistes d'alx

Publications (1)

Publication Number	Publication Date
HRP20110825T1 true HRP20110825T1 (hr)	2011-12-31

Family

ID=40404773

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR20110825T HRP20110825T1 (hr)	2007-12-18	2008-12-17	Derivati aminotriazola kao alx agonisti

Country Status (25)

Country	Link
US (1)	US8536209B2 (fr)
EP (1)	EP2225231B1 (fr)
JP (1)	JP4656674B2 (fr)
KR (1)	KR101213007B1 (fr)
CN (1)	CN101903378B (fr)
AR (1)	AR069801A1 (fr)
AT (1)	ATE520689T1 (fr)
AU (1)	AU2008337097B2 (fr)
BR (1)	BRPI0821115A8 (fr)
CA (1)	CA2706839C (fr)
CY (1)	CY1112465T1 (fr)
DK (1)	DK2225231T3 (fr)
HR (1)	HRP20110825T1 (fr)
IL (1)	IL206399A (fr)
MA (1)	MA31949B1 (fr)
MX (1)	MX2010006241A (fr)
MY (1)	MY153985A (fr)
NZ (1)	NZ586735A (fr)
PL (1)	PL2225231T3 (fr)
PT (1)	PT2225231E (fr)
RU (1)	RU2492167C2 (fr)
SI (1)	SI2225231T1 (fr)
TW (1)	TWI434685B (fr)
WO (1)	WO2009077990A1 (fr)
ZA (1)	ZA201005080B (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR069650A1 (es)	2007-12-14	2010-02-10	Actelion Pharmaceuticals Ltd	Derivados de aminopirazol como agonistas no peptidicos del receptor alx humano
PT2432760E (pt) *	2009-05-18	2013-10-21	Actelion Pharmaceuticals Ltd	Derivados de espiro [2,4] heptano ligados em ponte como agonistas do receptor fprl2 e/ou receptor alx
RU2544862C2 (ru)	2009-06-09	2015-03-20	Актелион Фармасьютиклз Лтд	Фторированные аминотриазольные производные
WO2010143158A1 (fr)	2009-06-12	2010-12-16	Actelion Pharmaceuticals Ltd	Dérivés de l'oxazole et du thiazole en tant qu'agonistes du récepteur alx
JP5917541B2 (ja)	2010-11-17	2016-05-18	アクテリオンファーマシューティカルズリミテッドＡｃｔｅｌｉｏｎＰｈａｒｍａｃｅｕｔｉｃａｌｓＬｔｄ	架橋スピロ［２．４］ヘプタンエステル誘導体
CN103249413B (zh) *	2010-12-07	2015-11-25	埃科特莱茵药品有限公司	作为脂氧素(alx)受体激动剂的羟基化氨基三唑衍生物
ES2526132T3 (es)	2010-12-07	2015-01-07	Actelion Pharmaceuticals Ltd.	Derivados de oxazolil-metiléter como agonistas del receptor de ALX
EP2707373A1 (fr)	2011-05-10	2014-03-19	Bayer Intellectual Property GmbH	(thio)carbonylamidines bicycliques
WO2013022766A1 (fr)	2011-08-05	2013-02-14	Flynn Gary A	Préparation et procédés d'utilisation d'ortho-aryle hétéroaryle à 5 chaînons -carboxamide contenant des inhibiteurs de kinases multicibles
CN102558117B (zh) *	2011-12-15	2014-10-08	北京金骄生物质化工有限公司	一种利用废弃生物质制备5-硝基-2-糠酸酯的方法
MA37618B1 (fr)	2012-05-16	2017-08-31	Actelion Pharmaceuticals Ltd	Dérivés pontés fluorés de spiro[2.4]heptane en tant qu'agonistes de récepteur alx
TW201348219A (zh)	2012-05-16	2013-12-01	Actelion Pharmaceuticals Ltd	作爲ａｌｘ受體激動劑之經１－（對－甲苯基）環丙基取代橋聯螺［２．４］庚烷衍生物
PT2855453T (pt)	2012-06-04	2017-03-09	Actelion Pharmaceuticals Ltd	Derivados de benzimidazol-prolina
AU2013328301A1 (en)	2012-10-10	2015-05-28	Actelion Pharmaceuticals Ltd	Orexin receptor antagonists which are [ortho bi (hetero-)aryl]-[2-(meta bi (hetero-)aryl)-pyrrolidin-1-yl]-methanone derivatives
BR112015012885A2 (pt) *	2012-12-03	2017-07-11	Hoffmann La Roche	composições triazol e imidazol substituídas
JP2016510810A (ja)	2013-03-12	2016-04-11	アクテリオンファーマシューティカルズリミテッドＡｃｔｅｌｉｏｎＰｈａｒｍａｃｅｕｔｉｃａｌｓＬｔｄ	オレキシン受容体アンタゴニストとしてのアゼチジンアミド誘導体
AR096686A1 (es)	2013-06-25	2016-01-27	Actelion Pharmaceuticals Ltd	Derivados de espiro[2.4]heptano puenteados sustituidos con difluoroetil-oxazol como agonistas del receptor de alx
WO2015007830A1 (fr)	2013-07-18	2015-01-22	Actelion Pharmaceuticals Ltd	Dérivés de spiro[2.4]heptane pontés, substitués par pipérazine, utilisés en tant qu'agonistes du récepteur alx
AR097279A1 (es)	2013-08-09	2016-03-02	Actelion Pharmaceuticals Ltd	Derivados de benzimidazolil-metil urea como agonistas del receptor de alx
EP3075726B1 (fr)	2013-11-28	2017-11-08	Kyorin Pharmaceutical Co., Ltd.	Dérivés d'urée ou leurs sels pharmacologiquement acceptables en tant qu'agonistes du récepteur fprl-1
PL3077391T3 (pl)	2013-12-04	2019-01-31	Idorsia Pharmaceuticals Ltd	Zastosowanie pochodnych benzimidazoloproliny
WO2016189877A1 (fr)	2015-05-27	2016-12-01	Kyorin Pharmaceutical Co., Ltd.	Dérivé d'urée ou sel pharmacologiquement acceptable de ce dernier
PE20180234A1 (es)	2015-05-27	2018-01-31	Kyorin Seiyaku Kk	Derivado de urea o sal farmacologicamente aceptable del mismo
WO2017091496A1 (fr) *	2015-11-24	2017-06-01	Bristol-Myers Squibb Company	Ciblage du récepteur 2 de peptide formyle / du récepteur de la lipoxine a4 (fpr2/alx) pour le traitement de maladies cardiaques
SI3762380T1 (sl)	2018-03-05	2022-09-30	Bristol-Myers Squibb Company	Receptor agonisti fenilpirolidinon peptida 2
US11629143B2 (en)	2020-10-01	2023-04-18	Vibliome Therapeutics, Llc	HipK4 inhibitors and uses thereof
JP7743010B2 (ja) *	2021-03-12	2025-09-24	国立大学法人長崎大学	ハロカルボニル化合物の製造方法

Family Cites Families (13)

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JPS62234018A (ja)	1986-04-02	1987-10-14	Rooto Seiyaku Kk	糖尿病併発症治療剤
AU2002359311A1 (en)	2001-10-26	2003-05-06	Government Of The United States Of America, As Represented By The Secretary, Department Of Health An	Amyloid ss is a ligand for fpr class receptors
US20050164305A1 (en)	2002-04-03	2005-07-28	Bayer Healthcare Ag	Diagnostics and therapeutics for diseases associated with n-formyl peptide receptor like 1 (fprl1)
BRPI0416272A (pt) *	2003-11-07	2007-01-09	Acadia Pharm Inc	usos do receptor fprl1, e de compostos, uso profilático de compostos, métodos de triagem para um composto capaz de afetar uma ou mais atividades de um receptor fprl1, de tratamento ou prevenção de inflamação, de identificação de um composto de indução de vasodilatação, para antagonismo de uma resposta vasoconstrutiva a um sulfidopeptìdeo leucotrieno em um indivìduo, e para estimulação de proliferação celular em um indivìduo, e, composto
ZA200610650B (en) *	2004-05-25	2009-04-29	Metabolex Inc	Substituted triazoles as modulators of PPAR and methods of their preparation
KR101260236B1 (ko) *	2004-12-13	2013-05-06	레오 파마 에이/에스	트리아졸 치환된 아미노벤조페논 화합물
EP1945617B1 (fr)	2005-11-03	2012-12-26	Merck Sharp & Dohme Corp.	Inhibiteurs de l'histone desacetylase a motifs d'aryle-pyrazolyle
CA2651072A1 (fr) *	2006-05-01	2007-11-08	Pfizer Products Inc.	Composes heterocycliques 2-amino-substitues a cycles fusionnes
RO128637A2 (ro)	2007-08-21	2013-07-30	Senomyx, Inc.	Identificarea receptorilor t2r umani care răspund la compuşii amari care extrag gustul amar din compoziţii, şi utilizarea acestora în analize pentru a identifica compuşii care inhibă () gustul amar în compoziţii şi utilizarea acestora
AR069650A1 (es)	2007-12-14	2010-02-10	Actelion Pharmaceuticals Ltd	Derivados de aminopirazol como agonistas no peptidicos del receptor alx humano
PT2432760E (pt)	2009-05-18	2013-10-21	Actelion Pharmaceuticals Ltd	Derivados de espiro [2,4] heptano ligados em ponte como agonistas do receptor fprl2 e/ou receptor alx
RU2544862C2 (ru)	2009-06-09	2015-03-20	Актелион Фармасьютиклз Лтд	Фторированные аминотриазольные производные
WO2010143158A1 (fr)	2009-06-12	2010-12-16	Actelion Pharmaceuticals Ltd	Dérivés de l'oxazole et du thiazole en tant qu'agonistes du récepteur alx

2008
- 2008-12-17 JP JP2010539015A patent/JP4656674B2/ja not_active Expired - Fee Related
- 2008-12-17 KR KR1020107015871A patent/KR101213007B1/ko not_active Expired - Fee Related
- 2008-12-17 WO PCT/IB2008/055375 patent/WO2009077990A1/fr active Application Filing
- 2008-12-17 MX MX2010006241A patent/MX2010006241A/es active IP Right Grant
- 2008-12-17 RU RU2010129272/04A patent/RU2492167C2/ru not_active IP Right Cessation
- 2008-12-17 MY MYPI2010002834A patent/MY153985A/en unknown
- 2008-12-17 CN CN200880122188.XA patent/CN101903378B/zh not_active Expired - Fee Related
- 2008-12-17 NZ NZ586735A patent/NZ586735A/en not_active IP Right Cessation
- 2008-12-17 CA CA2706839A patent/CA2706839C/fr not_active Expired - Fee Related
- 2008-12-17 HR HR20110825T patent/HRP20110825T1/hr unknown
- 2008-12-17 BR BRPI0821115A patent/BRPI0821115A8/pt not_active IP Right Cessation
- 2008-12-17 PT PT08862134T patent/PT2225231E/pt unknown
- 2008-12-17 SI SI200830412T patent/SI2225231T1/sl unknown
- 2008-12-17 TW TW097149199A patent/TWI434685B/zh not_active IP Right Cessation
- 2008-12-17 AU AU2008337097A patent/AU2008337097B2/en not_active Ceased
- 2008-12-17 PL PL08862134T patent/PL2225231T3/pl unknown
- 2008-12-17 DK DK08862134.7T patent/DK2225231T3/da active
- 2008-12-17 EP EP08862134A patent/EP2225231B1/fr not_active Not-in-force
- 2008-12-17 AT AT08862134T patent/ATE520689T1/de active
- 2008-12-17 US US12/809,545 patent/US8536209B2/en not_active Expired - Fee Related
- 2008-12-18 AR ARP080105522A patent/AR069801A1/es not_active Application Discontinuation
2010
- 2010-06-16 IL IL206399A patent/IL206399A/en not_active IP Right Cessation
- 2010-06-29 MA MA32968A patent/MA31949B1/fr unknown
- 2010-07-16 ZA ZA2010/05080A patent/ZA201005080B/en unknown
2011
- 2011-11-17 CY CY20111101111T patent/CY1112465T1/el unknown

Also Published As

Publication number	Publication date
RU2010129272A (ru)	2012-01-27
CN101903378B (zh)	2014-03-12
CA2706839A1 (fr)	2009-06-25
IL206399A (en)	2016-03-31
EP2225231B1 (fr)	2011-08-17
EP2225231A1 (fr)	2010-09-08
IL206399A0 (en)	2010-12-30
TWI434685B (zh)	2014-04-21
CA2706839C (fr)	2015-10-20
NZ586735A (en)	2012-06-29
ZA201005080B (en)	2011-12-28
BRPI0821115A2 (pt)	2015-06-16
MX2010006241A (es)	2010-06-30
CN101903378A (zh)	2010-12-01
JP4656674B2 (ja)	2011-03-23
PT2225231E (pt)	2011-10-19
AR069801A1 (es)	2010-02-17
BRPI0821115A8 (pt)	2017-12-26
US20100331378A1 (en)	2010-12-30
KR20100092516A (ko)	2010-08-20
CY1112465T1 (el)	2015-12-09
US8536209B2 (en)	2013-09-17
AU2008337097A1 (en)	2009-06-25
ATE520689T1 (de)	2011-09-15
TW200932216A (en)	2009-08-01
AU2008337097B2 (en)	2014-03-20
WO2009077990A1 (fr)	2009-06-25
PL2225231T3 (pl)	2012-01-31
KR101213007B1 (ko)	2012-12-20
SI2225231T1 (sl)	2011-12-30
MY153985A (en)	2015-04-30
HK1144158A1 (en)	2011-01-28
DK2225231T3 (da)	2011-10-17
MA31949B1 (fr)	2010-12-01
RU2492167C2 (ru)	2013-09-10
JP2011506594A (ja)	2011-03-03

Publication	Publication Date	Title
HRP20110825T1 (hr)	2011-12-31	Derivati aminotriazola kao alx agonisti
HRP20131105T1 (hr)	2013-12-20	Derivati aminopirazola
US8541457B2 (en)	2013-09-24	Aminothiazole derivatives as human stearoyl-CoA desaturase inhibitors
CA2660201C (fr)	2016-05-03	Composes organiques
JP2009513563A5 (fr)	2009-07-02
US7795444B2 (en)	2010-09-14	Human protein tyrosine phosphatase inhibitors and methods of use
US8815920B2 (en)	2014-08-26	Substituted amide compound
JP2020516671A5 (fr)	2020-12-17
JP2009524677A5 (fr)	2010-03-11
RU2005129729A (ru)	2006-03-20	Производные гетероарилкарбамоилбензола
NZ574405A (en)	2012-01-12	Human protein tyrosine phosphatase inhibitors and methods of use
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