[go: up one dir, main page]

HUP0103392A2 - Vizsgálati eljárás megtermékenyíthetetlen csírasejtek jelenlétének kimutatására - Google Patents

Vizsgálati eljárás megtermékenyíthetetlen csírasejtek jelenlétének kimutatására

Info

Publication number
HUP0103392A2
HUP0103392A2 HU0103392A HUP0103392A HUP0103392A2 HU P0103392 A2 HUP0103392 A2 HU P0103392A2 HU 0103392 A HU0103392 A HU 0103392A HU P0103392 A HUP0103392 A HU P0103392A HU P0103392 A2 HUP0103392 A2 HU P0103392A2
Authority
HU
Hungary
Prior art keywords
mammal
assay
indicate
unfertilizable
ivm
Prior art date
Application number
HU0103392A
Other languages
English (en)
Inventor
Svend Lindenberg
Anne Lis Mikkelsen
Original Assignee
Medi-Cult A/S.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK199900885A external-priority patent/DK199900885A/da
Application filed by Medi-Cult A/S. filed Critical Medi-Cult A/S.
Publication of HUP0103392A2 publication Critical patent/HUP0103392A2/hu

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743—Steroid hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0609—Oocytes, oogonia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C12N2501/48—Regulators of apoptosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999—Small molecules not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00—Cells related to new breeds of animals
    • C12N2517/10—Conditioning of cells for in vitro fecondation or nuclear transfer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/367—Infertility, e.g. sperm disorder, ovulatory dysfunction

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Developmental Biology & Embryology (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • General Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Steroid Compounds (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A találmány egy emlősből származó mintában legalább egy előrejelzőmarker vizsgálatára vonatkozik, amelyben legalább egy előrejelzőmarkerre vonatkozó specifikus reakció jelzi, hogy mikor vannak jelenaz emlősben in vitro érlelésre (IVÉ) és ezt követő in vitromegtermékenyítésre (IVM) alkalmas megtermékenyíthetetlen csírasejtek.Ez a vizsgálat különösen jól használható annak a megállapítására, hogymikor lesznek a megtermékenyíthetetlen csírasejtek, feltéve, hogyleszívták azokat, az MF-II stádiumba történt in vitro érlelés utánmegtermékenyítésre és a nőstény emlősbe történő beültetés utánterhességre alkalmasak. A vizsgálati minta test-szekrétumokból,köpetből, vérből, vizeletből, méhszekrétumokból vagy sejtekbőlszármazhat. Ó
HU0103392A 1998-06-22 1999-06-22 Vizsgálati eljárás megtermékenyíthetetlen csírasejtek jelenlétének kimutatására HUP0103392A2 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9011598P 1998-06-22 1998-06-22
DK199900885A DK199900885A (da) 1998-06-22 Fremgangsmåde for tildeling af et vilkårligt beløb på en given taletidskortkonto
PCT/DK1999/000344 WO1999067644A1 (en) 1998-06-22 1999-06-22 Assay to indicate the presence of non-fertilisable ova

Publications (1)

Publication Number Publication Date
HUP0103392A2 true HUP0103392A2 (hu) 2002-01-28

Family

ID=26064838

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0103392A HUP0103392A2 (hu) 1998-06-22 1999-06-22 Vizsgálati eljárás megtermékenyíthetetlen csírasejtek jelenlétének kimutatására

Country Status (23)

Country Link
US (2) US20010028878A1 (hu)
EP (2) EP1088056A1 (hu)
JP (1) JP2002519640A (hu)
CN (2) CN1607391A (hu)
AT (1) ATE407363T1 (hu)
AU (2) AU4360599A (hu)
BR (1) BR9911470A (hu)
CA (2) CA2335632A1 (hu)
DE (1) DE69939468D1 (hu)
EE (1) EE200000763A (hu)
ES (1) ES2313785T3 (hu)
HR (1) HRP20000888A2 (hu)
HU (1) HUP0103392A2 (hu)
ID (1) ID27197A (hu)
IL (2) IL140394A0 (hu)
IS (1) IS5768A (hu)
NO (2) NO20006519L (hu)
NZ (1) NZ509451A (hu)
PL (1) PL345318A1 (hu)
RU (1) RU2227916C2 (hu)
SK (1) SK19152000A3 (hu)
TR (1) TR200003830T2 (hu)
WO (2) WO1999067644A1 (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003076600A2 (en) 2002-03-08 2003-09-18 Mcgill University In vitro maturation of immature human oocytes
CN1675354A (zh) * 2002-06-17 2005-09-28 哥本哈根政府医院,位于海莱乌 体外受精
WO2005054449A1 (en) * 2003-11-26 2005-06-16 Applied Research Systems Ars Holding N.V. Use of il-6-type cytokines for maturation of oocytes
WO2007008521A1 (en) * 2005-07-07 2007-01-18 Lonnie Shea Stage specific follicle maturation systems
CN103275930B (zh) * 2013-06-20 2014-07-09 江苏皓康生物医药科技有限公司 一种卵母细胞体外成熟培养液及其制备方法
WO2015189301A1 (en) * 2014-06-10 2015-12-17 Polybiocept Ab Culture medium for cellular immunotherapy
WO2017143412A1 (en) * 2016-02-24 2017-08-31 Universidade Estadual Paulista "Júlioo De Mesquita Filho" - Unesp Follicular system for in vitro oocyte maturation and kit
CN110628705A (zh) * 2019-10-22 2019-12-31 山东畜牧兽医职业学院 一种驴胚胎冲洗液及其应用方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4614715A (en) * 1982-05-14 1986-09-30 The Board Of Trustees Of The University Of Illinois Predictive test for impending ovulation in mammals
RU2013989C1 (ru) * 1991-08-13 1994-06-15 Борис Васильевич Леонов Способ определения овуляции
GB9217866D0 (en) * 1992-08-21 1992-10-07 Unilever Plc Monitoring method
EP0734531A1 (en) * 1993-12-16 1996-10-02 Abbott Laboratories Methods and means for determining the female fertile period
GB9410345D0 (en) * 1994-05-24 1994-07-13 Univ Oxford Brookes Method of genetic testing
GB9603326D0 (en) * 1996-02-16 1996-04-17 Royal Free Hosp School Med Predictive assay
ATE213333T1 (de) * 1996-09-27 2002-02-15 Unilever Nv Überwachungsverfahren
GB9625175D0 (en) * 1996-12-04 1997-01-22 Medi Cult As Serum-free cell culture media

Also Published As

Publication number Publication date
NO20006519D0 (no) 2000-12-20
JP2002519640A (ja) 2002-07-02
IL140394A0 (en) 2002-02-10
EP1090300B1 (en) 2008-09-03
ID27197A (id) 2001-03-08
NO20006519L (no) 2001-02-21
IL140283A0 (en) 2002-02-10
ATE407363T1 (de) 2008-09-15
HRP20000888A2 (en) 2001-12-31
NO20006545D0 (no) 2000-12-21
CN1607391A (zh) 2005-04-20
EE200000763A (et) 2002-06-17
SK19152000A3 (sk) 2001-12-03
NZ509451A (en) 2003-03-28
EP1090300A1 (en) 2001-04-11
US20010028878A1 (en) 2001-10-11
RU2227916C2 (ru) 2004-04-27
EP1088056A1 (en) 2001-04-04
AU4360499A (en) 2000-01-10
BR9911470A (pt) 2001-03-20
PL345318A1 (en) 2001-12-03
CA2335632A1 (en) 1999-12-29
DE69939468D1 (de) 2008-10-16
CN1313951A (zh) 2001-09-19
AU4360599A (en) 2000-01-10
TR200003830T2 (tr) 2002-01-21
US20020115211A1 (en) 2002-08-22
WO1999067365A1 (en) 1999-12-29
NO20006545L (no) 2001-02-21
CN1161615C (zh) 2004-08-11
CA2335793A1 (en) 1999-12-29
AU760165B2 (en) 2003-05-08
IS5768A (is) 2000-12-12
ES2313785T3 (es) 2009-03-01
WO1999067644A1 (en) 1999-12-29

Similar Documents

Publication Publication Date Title
Macklon et al. Conception to ongoing pregnancy: the ‘black box’of early pregnancy loss
Esim et al. Diagnosis of premature rupture of membranes by identification of β-HCG in vaginal washing fluid
Kyama et al. Increased peritoneal and endometrial gene expression of biologically relevant cytokines and growth factors during the menstrual phase in women with endometriosis
Barragan et al. Human endometrial fibroblasts derived from mesenchymal progenitors inherit progesterone resistance and acquire an inflammatory phenotype in the endometrial niche in endometriosis
Pomp et al. Sex identification in mammals with polymerase chain reaction and its use to examine sex effects on diameter of day-10 or-11 pig embryos
Tarín et al. Human embryo biopsy on the 2nd day after insemination for preimplantation diagnosis: removal of a quarter of embryo retards cleavage
EP3444357B1 (en) Noninvasive detection method for screening healthily-growing blastulas
EP1154016A3 (en) Methods of isolating trophoblast cells from maternal blood
Correia-Alvarez et al. Expression and localization of interleukin 1 beta and interleukin 1 receptor (type I) in the bovine endometrium and embryo
HUP0103392A2 (hu) Vizsgálati eljárás megtermékenyíthetetlen csírasejtek jelenlétének kimutatására
TR201908019T4 (tr) Doğum öncesi teşhis için servikal mukusta fetal trofoblast hücrelerinin tanımlanması ve analizi.
Sobalska-Kwapis et al. New variants near RHOJ and C2, HLA-DRA region and susceptibility to endometriosis in the Polish population—the genome-wide association study
ATE513851T1 (de) Menschliches gen zur fruchtbarkeit entscheidend
Tveden-Nyborg et al. Analysis of the expression of putatively imprinted genes in bovine peri-implantation embryos
Chang et al. Minimally‐invasive early prenatal diagnosis using fluorescence in situ hybridization on samples from uterine lavage
AU704928B2 (en) Analytical and therapeutic agents
Osterlund et al. Temporal expression of platelet-derived growth factor (PDGF)-A and its receptor in human preimplantation embryos
CN113490753A (zh) 用于预测生育治疗成功的子宫内膜液
RU2001101921A (ru) Количественный анализ для выявления присутствия неоплодотворяемых яйцеклеток
JP2000513208A (ja) Ｉｖｆの成果についての予測アッセイ
WO2004109292A3 (de) Verfahren und mittel zur bestimmung von definierten zuständen oder veränderungen in der uterusschleimhaut oder im epithel anderer organe
JP2023533245A (ja) ダウン症候群診断用後成的バイオマーカー組成物及びその用途
Tay et al. Recognition of cervical neoplasia by the estimation of a free-radical reaction product (octadeca-9, 11-dienoic acid) in exfoliated cells
Kline et al. X-chromosome inactivation and ovarian age during the reproductive years
Marinić et al. Derivation of endometrial gland organoids from term post-partum placenta