HUP0201455A3 - Recombinant adenoviruses for the sodium/iodide symporter (nis) - Google Patents
Recombinant adenoviruses for the sodium/iodide symporter (nis)Info
- Publication number
- HUP0201455A3 HUP0201455A3 HU0201455A HUP0201455A HUP0201455A3 HU P0201455 A3 HUP0201455 A3 HU P0201455A3 HU 0201455 A HU0201455 A HU 0201455A HU P0201455 A HUP0201455 A HU P0201455A HU P0201455 A3 HUP0201455 A3 HU P0201455A3
- Authority
- HU
- Hungary
- Prior art keywords
- nis
- sodium
- recombinant adenoviruses
- iodide symporter
- symporter
- Prior art date
Links
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 title 1
- 102000003673 Symporters Human genes 0.000 title 1
- 108090000088 Symporters Proteins 0.000 title 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 title 1
- 229910052708 sodium Inorganic materials 0.000 title 1
- 239000011734 sodium Substances 0.000 title 1
- 241000701161 unidentified adenovirus Species 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/108—Plasmid DNA episomal vectors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9907449A FR2794771B1 (fr) | 1999-06-11 | 1999-06-11 | Adenovirus recombinants codant pour le transporteur specifique de l'iode (nis) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0201455A2 HUP0201455A2 (en) | 2002-08-28 |
| HUP0201455A3 true HUP0201455A3 (en) | 2004-12-28 |
Family
ID=9546704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0201455A HUP0201455A3 (en) | 1999-06-11 | 2000-06-08 | Recombinant adenoviruses for the sodium/iodide symporter (nis) |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20100080775A1 (hu) |
| EP (1) | EP1187919B1 (hu) |
| JP (2) | JP2003501107A (hu) |
| KR (1) | KR100708949B1 (hu) |
| CN (1) | CN1259418C (hu) |
| AU (1) | AU782934B2 (hu) |
| CA (1) | CA2376735A1 (hu) |
| DE (1) | DE60037189T2 (hu) |
| FR (1) | FR2794771B1 (hu) |
| HU (1) | HUP0201455A3 (hu) |
| IL (1) | IL146182A0 (hu) |
| MX (1) | MXPA01012004A (hu) |
| WO (1) | WO2000076450A2 (hu) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2794771B1 (fr) | 1999-06-11 | 2001-08-10 | Aventis Pharma Sa | Adenovirus recombinants codant pour le transporteur specifique de l'iode (nis) |
| US6586411B1 (en) | 2000-08-16 | 2003-07-01 | Mayo Foundation For Medical Education And Research | System for monitoring the location of transgenes |
| US6896881B1 (en) | 1999-09-24 | 2005-05-24 | Mayo Foundation For Medical Education And Research | Therapeutic methods and compositions using viruses of the recombinant paramyxoviridae family |
| US7118740B1 (en) | 2000-09-22 | 2006-10-10 | Mayo Foundation For Medical Education And Research | Method for limiting the growth of cancer cells using an attenuated measles virus |
| FR2837492B1 (fr) * | 2002-03-21 | 2007-07-20 | Commissariat Energie Atomique | Transporteur apical d'iode et ses applications |
| CA2690627C (en) * | 2007-06-15 | 2014-12-02 | Genelux Corporation | Microorganisms for imaging and/or treatment of tumors |
| CN102344489B (zh) * | 2010-08-05 | 2014-02-26 | 中国医药大学 | 经修饰的钠碘共同转运蛋白质及其应用 |
| US9951117B2 (en) | 2010-09-02 | 2018-04-24 | Mayo Foundation For Medical Education And Research | Vesicular stomatitis viruses |
| ES2545357T3 (es) | 2010-09-02 | 2015-09-10 | Mayo Foundation For Medical Education And Research | Virus de la estomatitis vesicular |
| ES2733211T3 (es) | 2011-04-15 | 2019-11-28 | Genelux Corp | Cepas clonales de virus vaccinia atenuados y métodos de uso de las mismas |
| US8859256B2 (en) | 2011-10-05 | 2014-10-14 | Genelux Corporation | Method for detecting replication or colonization of a biological therapeutic |
| TWI583224B (zh) * | 2015-03-12 | 2017-05-11 | 柯彥均 | 訊息之即時通訊方法 |
| EP3390428B1 (en) | 2016-02-23 | 2019-09-25 | Salk Institute for Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
| WO2017147269A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics |
| WO2018111767A1 (en) | 2016-12-12 | 2018-06-21 | Salk Institute For Biological Studies | Tumor-targeting synthetic adenoviruses and uses thereof |
| AU2019251356B2 (en) | 2018-04-09 | 2025-06-12 | Salk Institute For Biological Studies | Oncolytic adenovirus compositions with enhanced replication properties |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2601676B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Procede de preparation du taxol et du desacetyl-10 taxol |
| FR2601675B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2629818B1 (fr) * | 1988-04-06 | 1990-11-16 | Centre Nat Rech Scient | Procede de preparation du taxol |
| FR2662440B1 (fr) * | 1990-05-22 | 1992-07-31 | Rhone Poulenc Sante | Procede de preparation stereoselective de derives de la phenylisoserine. |
| FR2662441B1 (fr) | 1990-05-22 | 1992-10-23 | Rhone Poulenc Sante | Procede de preparation enantioselective de derives de la phenylisoserine. |
| WO1993000926A1 (en) | 1991-07-02 | 1993-01-21 | Children's Medical Center Corporation | Treatment of periodontal disease with protease inhibitors |
| FR2678833B1 (fr) | 1991-07-08 | 1995-04-07 | Rhone Poulenc Rorer Sa | Nouvelles compositions pharmaceutiques a base de derives de la classe des taxanes. |
| FR2698543B1 (fr) * | 1992-12-02 | 1994-12-30 | Rhone Poulenc Rorer Sa | Nouvelles compositions à base de taxoides. |
| FR2698871B1 (fr) * | 1992-12-09 | 1995-02-24 | Rhone Poulenc Rorer Sa | Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent. |
| FR2705361B1 (fr) | 1993-05-18 | 1995-08-04 | Centre Nat Rech Scient | Vecteurs viraux et utilisation en thérapie génique. |
| FR2705686B1 (fr) * | 1993-05-28 | 1995-08-18 | Transgene Sa | Nouveaux adénovirus défectifs et lignées de complémentation correspondantes. |
| FR2706486B1 (fr) | 1993-06-16 | 1995-09-01 | Rhone Poulenc Rorer Sa | Séquences nucléiques, vecteurs les contenant, compositions pharmaceutiques et utilisations thérapeutiques. |
| WO1995002697A1 (fr) | 1993-07-13 | 1995-01-26 | Rhone-Poulenc Rorer S.A. | Vecteurs adenoviraux defectifs et utilisation en therapie genique |
| WO1995003400A1 (en) | 1993-07-23 | 1995-02-02 | Johns Hopkins University School Of Medicine | Recombinationally targeted cloning in yeast artificial chromosomes |
| US7252989B1 (en) | 1994-04-04 | 2007-08-07 | Board Of Regents, The University Of Texas System | Adenovirus supervector system |
| FR2722191B1 (fr) | 1994-07-08 | 1996-08-23 | Rhone Poulenc Rorer Sa | Procede de preparation du trihydrate du (2r,3s)-3-tertbutoxycarbonylamino-2-hydroxy-3-phenylpropionate de 4-acetoxy2alpha-benzoyloxy-5beta,20epoxy-1,7beta,10beta trihydroxy-9-oxo-tax-11-en-13alpha-yle |
| FR2724945B1 (fr) | 1994-09-27 | 1996-12-27 | Centre Nat Rech Scient | Vecteurs viraux et utilisation en therapie genique |
| IL116816A (en) | 1995-01-20 | 2003-05-29 | Rhone Poulenc Rorer Sa | Cell for the production of a defective recombinant adenovirus or an adeno-associated virus and the various uses thereof |
| FR2730504B1 (fr) | 1995-02-13 | 1997-03-28 | Rhone Poulenc Rorer Sa | Procede de preparation de genomes d'adenovirus recombinants |
| US5652224A (en) * | 1995-02-24 | 1997-07-29 | The Trustees Of The University Of Pennsylvania | Methods and compositions for gene therapy for the treatment of defects in lipoprotein metabolism |
| US5863904A (en) * | 1995-09-26 | 1999-01-26 | The University Of Michigan | Methods for treating cancers and restenosis with P21 |
| CA2283090A1 (en) * | 1997-02-20 | 1998-08-27 | Hepavec Aktiengesellschaft Fur Gentherapie | Method for induction of apoptotic cell death in malignant cells, through reduction of the rb to apoptosis inducing proteins ratio |
| KR20010020342A (ko) * | 1997-04-28 | 2001-03-15 | 자끄 사비나 | 종양치료용 맥관형성 길항제의 아데노바이러스-매개 종양내 전달방법 |
| US6022708A (en) * | 1998-02-26 | 2000-02-08 | Genentech, Inc. | Fused |
| FR2778670B1 (fr) | 1998-05-18 | 2002-12-13 | Rhone Poulenc Rorer Sa | Methodes et compositions pour la production de particules virales |
| WO2000012738A1 (en) | 1998-08-27 | 2000-03-09 | Aventis Pharma S.A. | Targeted adenovirus vectors for delivery of heterologous genes |
| FR2794771B1 (fr) * | 1999-06-11 | 2001-08-10 | Aventis Pharma Sa | Adenovirus recombinants codant pour le transporteur specifique de l'iode (nis) |
-
1999
- 1999-06-11 FR FR9907449A patent/FR2794771B1/fr not_active Expired - Fee Related
-
2000
- 2000-06-08 AU AU55407/00A patent/AU782934B2/en not_active Ceased
- 2000-06-08 KR KR1020017015802A patent/KR100708949B1/ko not_active Expired - Fee Related
- 2000-06-08 IL IL14618200A patent/IL146182A0/xx unknown
- 2000-06-08 EP EP00940476A patent/EP1187919B1/fr not_active Expired - Lifetime
- 2000-06-08 DE DE60037189T patent/DE60037189T2/de not_active Expired - Lifetime
- 2000-06-08 JP JP2001502790A patent/JP2003501107A/ja active Pending
- 2000-06-08 MX MXPA01012004A patent/MXPA01012004A/es unknown
- 2000-06-08 HU HU0201455A patent/HUP0201455A3/hu unknown
- 2000-06-08 CA CA002376735A patent/CA2376735A1/fr not_active Abandoned
- 2000-06-08 CN CNB008085900A patent/CN1259418C/zh not_active Expired - Fee Related
- 2000-06-08 WO PCT/FR2000/001594 patent/WO2000076450A2/fr active IP Right Grant
-
2009
- 2009-09-25 US US12/567,076 patent/US20100080775A1/en not_active Abandoned
-
2012
- 2012-07-02 US US13/540,421 patent/US8642028B2/en not_active Expired - Fee Related
- 2012-10-11 JP JP2012225794A patent/JP2013048626A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE60037189D1 (de) | 2008-01-03 |
| IL146182A0 (en) | 2002-07-25 |
| CN1408022A (zh) | 2003-04-02 |
| US20100080775A1 (en) | 2010-04-01 |
| US20120269773A1 (en) | 2012-10-25 |
| EP1187919B1 (fr) | 2007-11-21 |
| AU5540700A (en) | 2001-01-02 |
| KR100708949B1 (ko) | 2007-04-18 |
| KR20020028893A (ko) | 2002-04-17 |
| JP2003501107A (ja) | 2003-01-14 |
| JP2013048626A (ja) | 2013-03-14 |
| FR2794771B1 (fr) | 2001-08-10 |
| CN1259418C (zh) | 2006-06-14 |
| DE60037189T2 (de) | 2008-10-09 |
| US8642028B2 (en) | 2014-02-04 |
| WO2000076450A2 (fr) | 2000-12-21 |
| MXPA01012004A (es) | 2002-05-06 |
| CA2376735A1 (fr) | 2000-12-21 |
| WO2000076450A3 (fr) | 2001-06-28 |
| AU782934B2 (en) | 2005-09-08 |
| EP1187919A2 (fr) | 2002-03-20 |
| FR2794771A1 (fr) | 2000-12-15 |
| HUP0201455A2 (en) | 2002-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |