HUP9901055A3 - Preparation of clavulanate salts - Google Patents

Preparation of clavulanate salts

Info

Publication number: HUP9901055A3
Authority: HU; Hungary
Prior art keywords: preparation; clavulanate salts; clavulanate; salts
Prior art date: 1995-04-20

Application number

HU9901055A

Other languages

English (en)

Original Assignee

Lek Tovarna Farmacevtskih

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-04-20

Filing date

1996-04-17

Publication date

2000-02-28

1996-04-17 Application filed by Lek Tovarna Farmacevtskih filed Critical Lek Tovarna Farmacevtskih

1999-08-30 Publication of HUP9901055A2 publication Critical patent/HUP9901055A2/hu

2000-02-28 Publication of HUP9901055A3 publication Critical patent/HUP9901055A3/hu

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Oncology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Cephalosporin Compounds (AREA)
Saccharide Compounds (AREA)

HU9901055A 1995-04-20 1996-04-17 Preparation of clavulanate salts HUP9901055A3 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SI9500134A SI9500134B (sl)	1995-04-20	1995-04-20	Postopek za pripravo čistih alkalijskih soli klavulanske kisline

Publications (2)

Publication Number	Publication Date
HUP9901055A2 HUP9901055A2 (hu)	1999-08-30
HUP9901055A3 true HUP9901055A3 (en)	2000-02-28

Family

ID=20431603

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU9901055A HUP9901055A3 (en)	1995-04-20	1996-04-17	Preparation of clavulanate salts

Country Status (29)

Country	Link
US (2)	US6180782B1 (hu)
EP (1)	EP0821687B1 (hu)
JP (1)	JPH11503744A (hu)
KR (1)	KR19990007892A (hu)
CN (1)	CN1118469C (hu)
AT (1)	ATE239736T1 (hu)
BG (1)	BG63395B1 (hu)
CA (1)	CA2218648A1 (hu)
CZ (1)	CZ293279B6 (hu)
DE (1)	DE69628002T2 (hu)
DK (1)	DK0821687T3 (hu)
DZ (1)	DZ2024A1 (hu)
EE (1)	EE9700263A (hu)
EG (1)	EG21091A (hu)
ES (1)	ES2199286T3 (hu)
HR (1)	HRP960186A2 (hu)
HU (1)	HUP9901055A3 (hu)
JO (1)	JO1902B1 (hu)
PL (1)	PL183465B1 (hu)
PT (1)	PT821687E (hu)
RO (1)	RO116195B1 (hu)
RU (1)	RU2166506C2 (hu)
SI (1)	SI9500134B (hu)
SK (1)	SK143797A3 (hu)
TN (1)	TNSN96061A1 (hu)
UA (1)	UA54389C2 (hu)
WO (1)	WO1996033197A1 (hu)
YU (1)	YU49113B (hu)
ZA (1)	ZA963119B (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AT400033B (de)	1992-03-10	1995-09-25	Biochemie Gmbh	Neues verfahren zur isolierung und reinigung von clavulansäure und zur herstellung von pharmakologisch verträglichen salzen derselben
SI9500134B (sl) *	1995-04-20	2004-04-30	Lek,	Postopek za pripravo čistih alkalijskih soli klavulanske kisline
SI9500265A1 (en) *	1995-08-28	1997-02-28	Lek Tovarna Farmacevtskih	Process for purification of the aqueous fermented broth filtrate of streptomyces sp. p 6621 ferm p 2804 by ultrafiltration
AT403375B (de) *	1995-11-15	1998-01-26	Biochemie Gmbh	Verfahren zur fällung von alkalisalzen der clavulansäure
WO1998021212A1 (en) *	1996-11-11	1998-05-22	Gist-Brocades B.V.	Process for the preparation of salts and esters of clavulanic acid
AT404728B (de) *	1996-11-27	1999-02-25	Biochemie Gmbh	Verfahren zur herstellung von clavulansäure-aminsalzen
AR015825A1 (es) *	1997-05-28	2001-05-30	Gist Brocades Bv	Produccion fermentativa de acido clavulanico bajo condiciones controladas de fosfato
GB0003305D0 (en)	2000-02-15	2000-04-05	Zeneca Ltd	Pyrimidine derivatives
US20040146918A1 (en) *	2000-02-18	2004-07-29	Weiner Michael L.	Hybrid nucleic acid assembly
KR100827898B1 (ko)	2000-05-13	2008-05-07	스미스클라인비이참피이엘시이	클라불란산의 염의 정제 방법
CN105384758B (zh) *	2015-12-01	2018-05-01	国药集团威奇达药业有限公司	克拉维酸胺盐的制备方法
CN109305978A (zh) *	2017-07-26	2019-02-05	山东睿鹰先锋制药有限公司	一种制备克拉维酸盐的新方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4110165A (en)	1974-04-20	1978-08-29	Beecham Group Limited	Process for the production of clavulanic acid
US4144242A (en)	1975-02-07	1979-03-13	Glaxo Laboratories Limited	Process for the purification of clavulanic acid
GB1578739A (en)	1976-07-23	1980-11-05	Beecham Group Ltd	Amine salts of clavulanic acid methods for their preparation and compositions containing them
US4454069A (en)	1979-08-24	1984-06-12	Beecham Group Limited	Clavulanic acid salts and their preparation from the tertiary butyl amine salt
DE3063683D1 (en)	1979-08-24	1983-07-14	Beecham Group Plc	Amine salt of clavulanic acid, its preparation and use
NZ213963A (en)	1984-10-27	1989-01-06	Antibioticos Sa	Production of clavulanic acid
AT399155B (de) *	1992-03-26	1995-03-27	Lek Tovarna Farmacevtskih	Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung
SI9300296B (sl) *	1992-06-11	1998-06-30	Smithkline Beecham P.L.C.	Postopek in intermedianti za pripravo klavulanske kisline
KR100200239B1 (ko) *	1992-10-21	1999-06-15	김충환	클라불란산 칼륨염의 제조방법
GB9305565D0 (en)	1993-03-18	1993-05-05	Smithkline Beecham Plc	Novel compounds and processes
NZ263564A (en)	1993-03-26	1995-12-21	Gist Brocades Nv	Tertiary, tertiary diamine mono and di salts of clavulanic acid; purification of clavulanic acid
GB9401969D0 (en)	1994-02-02	1994-03-30	Smithkline Beecham Plc	Process
SI9400107A (en) *	1994-03-02	1995-10-31	Lek Tovarna Farmacevtskih	New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.
GB9426261D0 (en)	1994-12-24	1995-02-22	Spurcourt Ltd	Clavulanic acid salts
BR9607258A (pt) *	1995-02-25	1997-12-30	Spurcourt Ltd	Sais de ácido clavul nico
SI9500074A (en) *	1995-03-10	1996-10-31	Lek Tovarna Farmacevtskih	Process for preparation of alkani salts of clavulanic acid.
SI9500134B (sl) *	1995-04-20	2004-04-30	Lek,	Postopek za pripravo čistih alkalijskih soli klavulanske kisline
WO1998021212A1 (en) *	1996-11-11	1998-05-22	Gist-Brocades B.V.	Process for the preparation of salts and esters of clavulanic acid

1995
- 1995-04-20 SI SI9500134A patent/SI9500134B/sl not_active IP Right Cessation
1996
- 1996-04-17 CN CN96194125A patent/CN1118469C/zh not_active Expired - Fee Related
- 1996-04-17 DE DE69628002T patent/DE69628002T2/de not_active Expired - Lifetime
- 1996-04-17 DK DK96910095T patent/DK0821687T3/da active
- 1996-04-17 KR KR1019970707415A patent/KR19990007892A/ko not_active Abandoned
- 1996-04-17 CZ CZ19973318A patent/CZ293279B6/cs not_active IP Right Cessation
- 1996-04-17 AT AT96910095T patent/ATE239736T1/de active
- 1996-04-17 RO RO97-01936A patent/RO116195B1/ro unknown
- 1996-04-17 WO PCT/GB1996/000921 patent/WO1996033197A1/en active IP Right Grant
- 1996-04-17 SK SK1437-97A patent/SK143797A3/sk unknown
- 1996-04-17 UA UA97105123A patent/UA54389C2/uk unknown
- 1996-04-17 JP JP8531550A patent/JPH11503744A/ja not_active Ceased
- 1996-04-17 EP EP96910095A patent/EP0821687B1/en not_active Expired - Lifetime
- 1996-04-17 US US08/930,527 patent/US6180782B1/en not_active Expired - Lifetime
- 1996-04-17 RU RU97119069/04A patent/RU2166506C2/ru not_active IP Right Cessation
- 1996-04-17 PT PT96910095T patent/PT821687E/pt unknown
- 1996-04-17 EE EE9700263A patent/EE9700263A/xx unknown
- 1996-04-17 PL PL96322888A patent/PL183465B1/pl unknown
- 1996-04-17 CA CA002218648A patent/CA2218648A1/en not_active Abandoned
- 1996-04-17 ES ES96910095T patent/ES2199286T3/es not_active Expired - Lifetime
- 1996-04-17 HU HU9901055A patent/HUP9901055A3/hu unknown
- 1996-04-19 TN TNTNSN96061A patent/TNSN96061A1/fr unknown
- 1996-04-19 ZA ZA963119A patent/ZA963119B/xx unknown
- 1996-04-19 HR HRP9500134A patent/HRP960186A2/hr not_active Application Discontinuation
- 1996-04-19 YU YU24796A patent/YU49113B/sh unknown
- 1996-04-20 EG EG33996A patent/EG21091A/xx active
- 1996-04-20 JO JO19961902A patent/JO1902B1/en active
- 1996-04-27 DZ DZ960066A patent/DZ2024A1/fr active
1997
- 1997-11-14 BG BG102043A patent/BG63395B1/bg unknown
2000
- 2000-12-14 US US09/738,434 patent/US6369219B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
KR19990007892A (ko)	1999-01-25
ZA963119B (en)	1996-10-24
EE9700263A (et)	1998-04-15
PT821687E (pt)	2003-09-30
DE69628002T2 (de)	2004-03-04
AU692091B2 (en)	1998-05-28
WO1996033197A1 (en)	1996-10-24
US6180782B1 (en)	2001-01-30
YU24796A (sh)	1998-09-18
RO116195B1 (ro)	2000-11-30
JPH11503744A (ja)	1999-03-30
PL322888A1 (en)	1998-03-02
CZ331897A3 (cs)	1998-03-18
CN1118469C (zh)	2003-08-20
BG102043A (en)	1998-11-30
HRP960186A2 (en)	1997-12-31
TNSN96061A1 (fr)	2005-03-15
SI9500134B (sl)	2004-04-30
BG63395B1 (bg)	2001-12-29
SK143797A3 (en)	1998-05-06
CA2218648A1 (en)	1996-10-24
ATE239736T1 (de)	2003-05-15
DK0821687T3 (da)	2003-08-18
DE69628002D1 (de)	2003-06-12
AU5340196A (en)	1996-11-07
ES2199286T3 (es)	2004-02-16
EP0821687B1 (en)	2003-05-07
EG21091A (en)	2000-10-31
DZ2024A1 (fr)	2002-10-21
US6369219B2 (en)	2002-04-09
PL183465B1 (pl)	2002-06-28
UA54389C2 (uk)	2003-03-17
HUP9901055A2 (hu)	1999-08-30
CN1185158A (zh)	1998-06-17
US20010025104A1 (en)	2001-09-27
YU49113B (sh)	2004-03-12
JO1902B1 (en)	1996-07-25
CZ293279B6 (cs)	2004-03-17
EP0821687A1 (en)	1998-02-04
RU2166506C2 (ru)	2001-05-10
SI9500134A1 (en)	1996-10-31

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