HUS2400033I1 - A biphenylsulfonamide endothelin and angiotensin ii receptor antagonist to treat glomerulosclerosis and iga-induced nephropathy - Google Patents
A biphenylsulfonamide endothelin and angiotensin ii receptor antagonist to treat glomerulosclerosis and iga-induced nephropathyInfo
- Publication number
- HUS2400033I1 HUS2400033I1 HUS2400033C HUS2400033C HUS2400033I1 HU S2400033 I1 HUS2400033 I1 HU S2400033I1 HU S2400033 C HUS2400033 C HU S2400033C HU S2400033 C HUS2400033 C HU S2400033C HU S2400033 I1 HUS2400033 I1 HU S2400033I1
- Authority
- HU
- Hungary
- Prior art keywords
- biphenylsulfonamide
- endothelin
- angiotensin
- iga
- receptor antagonist
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Psychology (AREA)
- Ophthalmology & Optometry (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16541909P | 2009-03-31 | 2009-03-31 | |
| US16544709P | 2009-03-31 | 2009-03-31 | |
| EP17157697.8A EP3222277B1 (en) | 2009-03-31 | 2010-03-29 | A biphenylsulfonamide endothelin and angiotensin ii receptor antagonist to treat glomerulosclerosis and iga-induced nephropathy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUS2400033I1 true HUS2400033I1 (en) | 2024-10-28 |
Family
ID=42828649
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE17157697A HUE049450T2 (en) | 2009-03-31 | 2010-03-29 | Endothelin and angiotensin II receptor antagonist for the treatment of biphenylsulfonamide glomerulosclerosis and IgA-induced nephropathy |
| HUE14155459A HUE033494T2 (en) | 2009-03-31 | 2010-03-29 | A biphenylsulfonamide endothelin and angiotensin ii receptor antagonist to treat glomerulosclerosis |
| HUS2400033C HUS2400033I1 (en) | 2009-03-31 | 2024-09-30 | A biphenylsulfonamide endothelin and angiotensin ii receptor antagonist to treat glomerulosclerosis and iga-induced nephropathy |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE17157697A HUE049450T2 (en) | 2009-03-31 | 2010-03-29 | Endothelin and angiotensin II receptor antagonist for the treatment of biphenylsulfonamide glomerulosclerosis and IgA-induced nephropathy |
| HUE14155459A HUE033494T2 (en) | 2009-03-31 | 2010-03-29 | A biphenylsulfonamide endothelin and angiotensin ii receptor antagonist to treat glomerulosclerosis |
Country Status (18)
| Country | Link |
|---|---|
| US (4) | US20140142149A1 (en) |
| EP (4) | EP3708163A1 (en) |
| JP (3) | JP2012522058A (en) |
| CN (2) | CN104107176A (en) |
| CY (2) | CY1119232T1 (en) |
| DK (2) | DK3222277T3 (en) |
| ES (2) | ES2811342T3 (en) |
| FI (1) | FIC20240031I1 (en) |
| FR (1) | FR24C1038I1 (en) |
| HR (2) | HRP20171197T1 (en) |
| HU (3) | HUE049450T2 (en) |
| LT (3) | LT2732818T (en) |
| NL (1) | NL301291I2 (en) |
| PL (2) | PL3222277T3 (en) |
| PT (2) | PT3222277T (en) |
| SI (2) | SI2732818T1 (en) |
| SM (2) | SMT202000269T1 (en) |
| WO (1) | WO2010114801A1 (en) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2011280969A1 (en) | 2010-07-23 | 2013-02-07 | Trustees Of Boston University | Anti-Despr inhibitors as therapeutics for inhibition of pathological angiogenesis and tumor cell invasiveness and for molecular imaging and targeted delivery |
| AR083417A1 (en) * | 2010-10-14 | 2013-02-21 | Novartis Ag | PHARMACEUTICAL COMPOSITIONS CONTAINING AN INHIBITOR DGAT1 |
| US20130022551A1 (en) * | 2011-07-22 | 2013-01-24 | Trustees Of Boston University | DEspR ANTAGONISTS AND AGONISTS AS THERAPEUTICS |
| EP3763374A1 (en) * | 2011-10-17 | 2021-01-13 | Lexicon Pharmaceuticals, Inc. | Solid dosage forms of (s)-ethyl 2-amino-3-(4-(2-amino-6-((r)-1-(4-chloro-2-(3-methyl-1h-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoate |
| ES2790358T3 (en) | 2011-12-28 | 2020-10-27 | Global Blood Therapeutics Inc | Substituted Heteroaryl Aldehyde Compounds and Methods for Their Use in Increasing Tissue Oxygenation |
| EP2797416B1 (en) | 2011-12-28 | 2017-08-09 | Global Blood Therapeutics, Inc. | Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation |
| WO2013149258A2 (en) | 2012-03-30 | 2013-10-03 | Charles Drew University of Medicine and Science | Compositions and methods for treating or preventing metabolic syndrome disorders |
| US20140271923A1 (en) | 2013-03-14 | 2014-09-18 | Christopher Brian Reid | Compositions & formulations for preventing and treating chronic diseases that cluster in patients such as cardiovascular disease, diabetes, obesity, polycystic ovary syndrome, hyperlipidemia and hypertension, as well as for preventing and treating other diseases and conditions |
| US9458139B2 (en) | 2013-03-15 | 2016-10-04 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| CN105246477A (en) | 2013-03-15 | 2016-01-13 | 全球血液疗法股份有限公司 | Compounds and their use for regulating hemoglobin |
| PE20161035A1 (en) | 2013-03-15 | 2016-11-13 | Global Blood Therapeutics Inc | COMPOUNDS AND USES OF THESE FOR THE MODULATION OF HEMOGLOBIN |
| US8952171B2 (en) | 2013-03-15 | 2015-02-10 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| KR102293060B1 (en) | 2013-03-15 | 2021-08-23 | 글로벌 블러드 테라퓨틱스, 인크. | Compounds and uses thereof for the modulation of hemoglobin |
| PE20160194A1 (en) | 2013-06-13 | 2016-04-20 | Akebia Therapeutics Inc | COMPOSITIONS AND METHODS TO TREAT ANEMIA |
| EA201992707A1 (en) | 2013-11-18 | 2020-06-30 | Глобал Блад Терапьютикс, Инк. | COMPOUNDS AND THEIR APPLICATIONS FOR HEMOGLOBIN MODULATION |
| US12168004B2 (en) | 2014-02-05 | 2024-12-17 | Merck Sharp & Dohme Llc | Treatment of migraine |
| CN105960397B (en) * | 2014-02-05 | 2020-09-04 | 默沙东公司 | CGRP - tablet formulation of active compound |
| HUE053706T2 (en) | 2014-02-07 | 2021-07-28 | Global Blood Therapeutics Inc | Crystalline polymorph of the free base of 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde |
| CN104367576A (en) * | 2014-10-24 | 2015-02-25 | 南方医科大学南方医院 | Use of compound ICG-001 in preparation of medicine for treating hypertension |
| US10202457B2 (en) | 2015-08-24 | 2019-02-12 | Trustees Of Boston University | Anti-DEspR monoclonal antibody targeted therapy and imaging for cancer and stroke |
| WO2017096230A1 (en) | 2015-12-04 | 2017-06-08 | Global Blood Therapeutics, Inc. | Dosing regimens for 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde |
| TWI663160B (en) | 2016-05-12 | 2019-06-21 | 全球血液治療公司 | Process for synthesizing 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)-pyridin-3-yl)methoxy)benzaldehyde |
| TW202332423A (en) * | 2016-10-12 | 2023-08-16 | 美商全球血液治療公司 | Tablets comprising 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde |
| US20190262317A1 (en) * | 2016-10-13 | 2019-08-29 | Retrophin, Inc. | Biphenyl sulfonamide compounds for the treatment of kidney diseases or disorders |
| EP3615002A4 (en) * | 2017-04-25 | 2021-01-06 | Proteus Digital Health, Inc. | LISINOPRIL COMPOSITIONS WITH A TAKE-UP EVENT MARKER |
| EP3684400A4 (en) | 2017-09-18 | 2021-06-16 | Trustees of Boston University | Methods for treating netosis and neutrophil activation |
| US12383545B1 (en) | 2018-06-08 | 2025-08-12 | Allergan Pharmaceuticals International Limited | Treatment of migraine |
| US10953107B2 (en) | 2018-06-15 | 2021-03-23 | Trustees Of Boston University | Polypeptide compositions and methods for site-specific targeting of therapeutic agents |
| EP3860975B1 (en) | 2018-10-01 | 2023-10-18 | Global Blood Therapeutics, Inc. | Modulators of hemoglobin for the treatment of sickle cell disease |
| KR20210081338A (en) | 2018-10-04 | 2021-07-01 | 트래버르 테라퓨틱스, 인코포레이티드 | Biphenyl sulfonamide compounds for the treatment of type IV collagen diseases |
| EP3897834A1 (en) * | 2018-12-21 | 2021-10-27 | Travere Therapeutics, Inc. | Amorphous sparsentan compositions |
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| WO2020166710A1 (en) | 2019-02-15 | 2020-08-20 | 国立大学法人東北大学 | 1, 3-dioxolan derivative |
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| US793898A (en) | 1905-03-01 | 1905-07-04 | William Mcintosh | Locomotive-tender frame. |
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