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IL114235A0 - Oligonucleotide conjugates and processes for noninvasive diagnosis utilizing the same - Google Patents

Oligonucleotide conjugates and processes for noninvasive diagnosis utilizing the same

Info

Publication number
IL114235A0
IL114235A0 IL11423595A IL11423595A IL114235A0 IL 114235 A0 IL114235 A0 IL 114235A0 IL 11423595 A IL11423595 A IL 11423595A IL 11423595 A IL11423595 A IL 11423595A IL 114235 A0 IL114235 A0 IL 114235A0
Authority
IL
Israel
Prior art keywords
processes
same
oligonucleotide conjugates
noninvasive diagnosis
diagnosis utilizing
Prior art date
Application number
IL11423595A
Other languages
English (en)
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4424923A external-priority patent/DE4424923A1/de
Priority claimed from DE19944445076 external-priority patent/DE4445076A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL114235A0 publication Critical patent/IL114235A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/12—Macromolecular compounds
    • A61K49/126—Linear polymers, e.g. dextran, inulin, PEG
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL11423595A 1994-07-14 1995-06-20 Oligonucleotide conjugates and processes for noninvasive diagnosis utilizing the same IL114235A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4424923A DE4424923A1 (de) 1994-07-14 1994-07-14 Konjugate aus Metallkomplexen und Oligonucleotiden, die spezifisch an bestimmte Zielstrukturen binden für MRI
DE19944445076 DE4445076A1 (de) 1994-12-05 1994-12-05 Konjugate aus Metallkomplexen und Oligonucleotiden, die spezifisch an bestimmte Zielstrukturen binden, diese Konjugate enthaltende Mittel, deren Verwendung in der NMR-Diagnostik sowie Verfahren zu deren Herstellung

Publications (1)

Publication Number Publication Date
IL114235A0 true IL114235A0 (en) 1995-10-31

Family

ID=25938360

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11423595A IL114235A0 (en) 1994-07-14 1995-06-20 Oligonucleotide conjugates and processes for noninvasive diagnosis utilizing the same

Country Status (5)

Country Link
EP (1) EP0770146A1 (xx)
JP (1) JPH10511842A (xx)
AU (1) AU3109095A (xx)
IL (1) IL114235A0 (xx)
WO (1) WO1996002669A1 (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11507027A (ja) * 1995-06-07 1999-06-22 シェリング アクチェンゲゼルシャフト 特定の標的構造に特異的に結合するフェライト及びオリゴヌクレオチドのコンジュゲート
DE19741084A1 (de) * 1997-09-18 1999-03-25 Knoell Hans Forschung Ev Hochaffine Nukleinsäuremoleküle mit funktionellen Gruppen zur spezifischen Erkennung von Zielmolekülen, ihre Herstellung und Verwendung
WO2002096417A1 (en) 2001-05-31 2002-12-05 Miravant Pharmaceuticals, Inc. Substituted porphyrin and azaporphyrin derivatives and their use in photodynamic therapy, radioimaging and mri diagnosis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5057302A (en) * 1987-02-13 1991-10-15 Abbott Laboratories Bifunctional chelating agents
US4962045A (en) * 1988-05-02 1990-10-09 The Perkin-Elmer Corporation Time-resolved fluorimetric detection of lanthanide labeled nucleotides
US5559207A (en) * 1989-03-06 1996-09-24 Board Of Regents, University Of Texas Texaphyrin metal complex mediated ester hydrolysis
ES2139578T3 (es) * 1990-05-23 2000-02-16 Isis Pharmaceuticals Inc Composiciones y procedimiento para modular la actividad del arn mediante la modificacion de la estructura protectora 5' del arn.
ES2108109T3 (es) * 1991-02-14 1997-12-16 Dade Microscan Inc Nuevos oligonucleotidos conjugados con quelatos de lantanidos.
WO1993012230A1 (en) * 1991-12-13 1993-06-24 Sri International Triple-helix formation at (punpyn).(punpyn) tracts
FR2697254A1 (fr) * 1992-10-22 1994-04-29 Genset Sa Conjugués constitués par un oligonucléotide lié à des dérivés de métalloporphyrine cationique, leur préparation et leur utilisation.

Also Published As

Publication number Publication date
EP0770146A1 (en) 1997-05-02
AU3109095A (en) 1996-02-16
WO1996002669A1 (en) 1996-02-01
JPH10511842A (ja) 1998-11-17

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