IL119078A - Substituted benzylaminopiperidine compounds and pharmaceutical compositions comprising them - Google Patents

Substituted benzylaminopiperidine compounds and pharmaceutical compositions comprising them

Info

Publication number: IL119078A
Authority: IL; Israel
Prior art keywords: pharmaceutical compositions; substituted; compounds; substituted benzylaminopiperidine; benzylaminopiperidine compounds
Prior art date: 1995-08-24

Application number

IL11907896A

Other languages

English (en)

Other versions

IL119078A0 (en

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-08-24

Filing date

1996-08-15

Publication date

2003-11-23

1996-08-15 Application filed by Pfizer filed Critical Pfizer

1996-11-14 Publication of IL119078A0 publication Critical patent/IL119078A0/xx

2003-11-23 Publication of IL119078A publication Critical patent/IL119078A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Otolaryngology (AREA)
Urology & Nephrology (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IL11907896A 1995-08-24 1996-08-15 Substituted benzylaminopiperidine compounds and pharmaceutical compositions comprising them IL119078A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IB9500683		1995-08-24

Publications (2)

Publication Number	Publication Date
IL119078A0 IL119078A0 (en)	1996-11-14
IL119078A true IL119078A (en)	2003-11-23

Family

ID=11004362

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL11907896A IL119078A (en)	1995-08-24	1996-08-15	Substituted benzylaminopiperidine compounds and pharmaceutical compositions comprising them

Country Status (41)

Country	Link
US (1)	US6506775B1 (fr)
EP (2)	EP1114817B1 (fr)
JP (1)	JP3084069B2 (fr)
KR (1)	KR100288673B1 (fr)
CN (1)	CN1153764C (fr)
AP (1)	AP643A (fr)
AR (1)	AR006305A1 (fr)
AT (2)	ATE258166T1 (fr)
AU (1)	AU702698B2 (fr)
BG (1)	BG64126B1 (fr)
BR (1)	BR9609989A (fr)
CA (1)	CA2227814C (fr)
CO (1)	CO4480738A1 (fr)
CZ (1)	CZ297543B6 (fr)
DE (2)	DE69616817T2 (fr)
DK (2)	DK1114817T3 (fr)
DZ (1)	DZ2086A1 (fr)
ES (2)	ES2163017T3 (fr)
HR (1)	HRP960386B1 (fr)
HU (1)	HU225480B1 (fr)
IL (1)	IL119078A (fr)
IS (1)	IS1947B (fr)
MA (1)	MA23961A1 (fr)
MX (1)	MX9801467A (fr)
MY (1)	MY114800A (fr)
NO (1)	NO310720B1 (fr)
NZ (1)	NZ308207A (fr)
OA (1)	OA10666A (fr)
PE (2)	PE1398A1 (fr)
PL (1)	PL186773B1 (fr)
PT (2)	PT1114817E (fr)
RO (1)	RO119299B1 (fr)
RU (1)	RU2152930C2 (fr)
SI (2)	SI1114817T1 (fr)
SK (1)	SK282925B6 (fr)
TN (1)	TNSN96107A1 (fr)
TR (1)	TR199800300T1 (fr)
TW (1)	TW340842B (fr)
UA (1)	UA48981C2 (fr)
WO (1)	WO1997008144A1 (fr)
YU (1)	YU49122B (fr)

Families Citing this family (59)

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Publication number	Priority date	Publication date	Assignee	Title
MX9706196A (es) *	1996-08-14	1998-02-28	Pfizer	Compuestos triciclicos de piperidinilamino como antagonistas de la sustancia p.
TW426667B (en) *	1997-11-19	2001-03-21	Pfizer	Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists
US6777428B1 (en)	1999-02-10	2004-08-17	Eli Lilly And Company	5-HT1f agonist
IL145945A0 (en) *	1999-05-06	2002-07-25	Pfizer Prod Inc	Substituted benzolactam compounds
RS49964B (sr)	1999-05-17	2008-09-29	Pfizer Products Inc.,	Postupak za dobijanje 2-fenil-3-aminopiridina,njegovih supstituisanih fenil derivata, i njegovih soli
EE04719B1 (et) *	1999-05-21	2006-10-16	Pfizer Products Inc.	1-trifluorometüül-4-hüdroksü-7-piperidinüül-aminometüülkromaani derivaadid
DK1095939T3 (da) *	1999-10-18	2004-04-13	Pfizer Prod Inc	Fremgangsmåde til fremstilling af cykliske piperidinylaminomethyltrifluormethyletherforbindelser
CA2324116A1 (fr) *	1999-10-25	2001-04-25	Susan Beth Sobolov-Jaynes	Antagonistes du recepteur nk-1 et eletriptan pour le traitement de la migraine
CA2389306C (fr)	1999-11-03	2010-03-30	Albany Molecular Research, Inc.	Tetrahydroisoquinolines a substitution aryle et heteroaryle et utilisation de ces composes pour bloquer le recaptage de norepinephrine, de dopamine et de serotonine
US7163949B1 (en)	1999-11-03	2007-01-16	Amr Technology, Inc.	4-phenyl substituted tetrahydroisoquinolines and use thereof
BR0112350A (pt)	2000-07-11	2003-06-24	Albany Molecular Res Inc	Composto, composição farmacêutica, e, método de tratar um animal afligido por um distúrbio neurológico ou psicológico
PA8525601A1 (es) *	2000-08-21	2002-04-25	Hoffmann La Roche	Profarmacos de (3s,4s)-4-bencil-1-[2-(4-hidroxi-bencenosulfonil)-etil]-piperidin-3-ol
US20020049211A1 (en) *	2000-09-06	2002-04-25	Sobolov-Jaynes Susan Beth	Combination treatment for depression and anxiety
EP1192952A3 (fr) *	2000-09-28	2003-03-26	Pfizer Products Inc.	Composition pour le traitement de la dépression et de l'anxieté contenant un antagoniste du recepteur NK-3 et un antagoniste du récepteur NK-1
US6911544B2 (en)	2002-10-23	2005-06-28	Pfizer Inc.	Process for the preparation of (S,S)-cis-2-phenyl-3-aminopiperidine
CA2518839A1 (fr)	2003-04-18	2004-11-04	Eli Lilly And Company	Composes (piperidinyloxy)phenyle, (piperidinyloxy)pyridinyle, (piperidinylsulfanyl)phenyle et (piperidinylsulfanyl)pyridinyle utilises comme agonistes des recepteurs 5-ht<sb>1f</sb>
EP1753722A2 (fr) *	2004-05-21	2007-02-21	Pfizer Products Inc.	Metabolites de (+)-(2s, 3s)-3-(2-methoxy-5-trifluoromethoxybenzylamino)-2-phenyl-piperidine
AU2005274927B2 (en)	2004-07-15	2011-11-03	Albany Molecular Research, Inc.	Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
ATE550019T1 (de)	2005-05-17	2012-04-15	Merck Sharp & Dohme	Cis-4-ä(4-chlorophenyl)sulfonylü-4-(2,5- difluorophenyl)cyclohexanepropansäure zur behandlug von krebs
JP5258561B2 (ja)	2005-07-15	2013-08-07	アルバニーモレキュラーリサーチ，インコーポレイテッド	アリール置換およびヘテロアリール置換テトラヒドロベンズアゼピンならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するためのその使用
AU2006297443B2 (en)	2005-09-29	2010-08-12	Merck Sharp & Dohme Corp.	Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
SE529246C2 (sv) *	2005-10-13	2007-06-12	Neurosearch Sweden Ab	Nya disubstituerade fenyl-piperidiner som modulatorer för dopaminneurotransmission
GB0603041D0 (en)	2006-02-15	2006-03-29	Angeletti P Ist Richerche Bio	Therapeutic compounds
JP5489333B2 (ja)	2006-09-22	2014-05-14	メルク・シャープ・アンド・ドーム・コーポレーション	脂肪酸合成阻害剤を用いた治療の方法
US20110218176A1 (en)	2006-11-01	2011-09-08	Barbara Brooke Jennings-Spring	Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
PL2805945T3 (pl)	2007-01-10	2019-09-30	Msd Italia S.R.L.	Indazole podstawione grupą amidową jako inhibitory polimerazy poli(adp-rybozy) - (parp)
CA2682727C (fr)	2007-04-02	2016-03-22	Banyu Pharmaceutical Co., Ltd.	Derive d'indoledione
CA2690191C (fr)	2007-06-27	2015-07-28	Merck Sharp & Dohme Corp.	Derives de 4-carboxybenzylamino utilises en tant qu'inhibiteurs de l'histone desacetylase
CN102014631A (zh)	2008-03-03	2011-04-13	泰格尔医药科技公司	酪氨酸激酶抑制剂
EP2264029A4 (fr)	2008-03-31	2011-08-24	Kowa Co	Dérivé de 1,3-dihydroisobenzofurane
US9156812B2 (en)	2008-06-04	2015-10-13	Bristol-Myers Squibb Company	Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
EP2413932A4 (fr)	2009-04-01	2012-09-19	Merck Sharp & Dohme	Inhibiteurs de l'activité akt
ES2528404T3 (es)	2009-05-12	2015-02-10	Bristol-Myers Squibb Company	Formas cristalinas de (S)-7-([1,2,4]triazol[1,5-a]piridin-6-il)-4-(3,4-diclorofenil)-1,2,3,4-tetrahidroisoquinolina y sus usos
WO2010132437A1 (fr)	2009-05-12	2010-11-18	Albany Molecular Research, Inc.	Aryle, hétéroaryle et tétrahydroisoquinolines à hétérocycle substitué et leur utilisation
CN102595902B (zh)	2009-05-12	2015-04-29	阿尔巴尼分子研究公司	7-([1,2,4]三唑并[1,5-a]吡啶-6-基)-4-(3,4-二氯苯基)-1,2,3,4-四氢异喹啉及其用途
NZ599343A (en)	2009-10-14	2014-05-30	Merck Sharp & Dohme	Substituted piperidines that increase p53 activity and the uses thereof
EP2584903B1 (fr)	2010-06-24	2018-10-24	Merck Sharp & Dohme Corp.	Nouveaux composés hétérocycliques utilisés comme inhibiteurs de erk
WO2012018754A2 (fr)	2010-08-02	2012-02-09	Merck Sharp & Dohme Corp.	Inhibition à médiation par interférence arn de caténine (protéine associée à cadhérine), expression du gène bêta 1 (ctnnb1) à l'aide de petit acide nucléique interférent (sian)
EP4079856A1 (fr)	2010-08-17	2022-10-26	Sirna Therapeutics, Inc.	Inhibition médiée par des arn interférents de l'expression génique du virus de l'hépatite b (vhb) à l'aide de petits acides nucléiques interférents (pani)
EP2608669B1 (fr)	2010-08-23	2016-06-22	Merck Sharp & Dohme Corp.	Nouveaux dérivés de pyrazolo[1,5-a]pyrimidine utilisés comme inhibiteurs de mtor
EP2613782B1 (fr)	2010-09-01	2016-11-02	Merck Sharp & Dohme Corp.	Dérivés d'indazole utilisables en tant qu'inhibiteurs de la voie erk
WO2012036997A1 (fr)	2010-09-16	2012-03-22	Schering Corporation	Dérivés condensés de pyrazole utilisés comme nouveaux inhibiteurs erk
ES2663009T3 (es)	2010-10-29	2018-04-10	Sirna Therapeutics, Inc.	Inhibición de la expresión génica mediada por interferencia por ARN utilizando ácidos nucleicos de interferencia cortos (ANic)
EP2654748B1 (fr)	2010-12-21	2016-07-27	Merck Sharp & Dohme Corp.	Dérivés d'indazole utiles en tant qu'inhibiteurs de erk
CA2831730A1 (fr)	2011-04-21	2012-10-26	Piramal Enterprises Limited	Forme cristalline d'un sel d'un derive de morpholinosulfonylindole et son procede de preparation
US9023865B2 (en)	2011-10-27	2015-05-05	Merck Sharp & Dohme Corp.	Compounds that are ERK inhibitors
EP3453762B1 (fr)	2012-05-02	2021-04-21	Sirna Therapeutics, Inc.	Compositions d'acide nucléique interférent court (sina)
US9233979B2 (en)	2012-09-28	2016-01-12	Merck Sharp & Dohme Corp.	Compounds that are ERK inhibitors
WO2014078568A1 (fr)	2012-11-14	2014-05-22	The Johns Hopkins University	Méthodes et compositions pour le traitement de la schizophrénie
BR112015012295A8 (pt)	2012-11-28	2023-03-14	Merck Sharp & Dohme	Uso de um inibidor de wee1, e, kit para identificar um paciente com câncer
BR112015013611A2 (pt)	2012-12-20	2017-11-14	Merck Sharp & Dohme	composto, e, composição farmacêutica
US9540377B2 (en)	2013-01-30	2017-01-10	Merck Sharp & Dohme Corp.	2,6,7,8 substituted purines as HDM2 inhibitors
US20160194368A1 (en)	2013-09-03	2016-07-07	Moderna Therapeutics, Inc.	Circular polynucleotides
US10975084B2 (en)	2016-10-12	2021-04-13	Merck Sharp & Dohme Corp.	KDM5 inhibitors
WO2019094311A1 (fr)	2017-11-08	2019-05-16	Merck Sharp & Dohme Corp.	Inhibiteurs de prmt5
EP3706747B1 (fr)	2017-11-08	2025-09-03	Merck Sharp & Dohme LLC	Inhibiteurs de prmt5
AU2019317549A1 (en)	2018-08-07	2021-02-25	Msd International Gmbh	PRMT5 inhibitors
EP3833667B1 (fr)	2018-08-07	2024-03-13	Merck Sharp & Dohme LLC	Inhibiteurs de prmt5
EP3833668B1 (fr)	2018-08-07	2025-03-19	Merck Sharp & Dohme LLC	Inhibiteurs de prmt5

Family Cites Families (11)

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US5232929A (en) *	1990-11-28	1993-08-03	Pfizer Inc.	3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
US5364943A (en) *	1991-11-27	1994-11-15	Pfizer Inc.	Preparation of substituted piperidines
JPH0794440B2 (ja) *	1991-03-26	1995-10-11	フアイザー・インコーポレイテツド	置換ピペリジンの立体選択的製造
HU221634B1 (hu) *	1991-06-20	2002-12-28	Pfizer Inc.	Nitrogéntartalmú heterociklusos vegyületek fluor-alkoxi-benzilamino-származékai, eljárás előállításukra és az ezeket tartalmazó gyógyszerkészítmények
US5340826A (en) *	1993-02-04	1994-08-23	Pfizer Inc.	Pharmaceutical agents for treatment of urinary incontinence
US5393762A (en) *	1993-06-04	1995-02-28	Pfizer Inc.	Pharmaceutical agents for treatment of emesis
EP0653208A3 (fr) *	1993-11-17	1995-10-11	Pfizer	Antagonistes de la substance P pour le traitement et la prévention de l'erythème solaire.
EP0655246A1 (fr) *	1993-11-30	1995-05-31	Pfizer Inc.	Antagonistes de la substance P pour le traitement des maladies causées par Helicobacter Pylori ou d'autres bacteries spirales, ureare-positives, gram-négatives
CA2216701A1 (fr)	1995-03-27	1996-10-03	Akira Okayama	Derives de piperidine
ATE223896T1 (de) *	1995-12-21	2002-09-15	Pfizer	3-((5-substituierte benzyl)amino)-2- phenylpiperidine als substance-p-antagonisten
US5990125A (en)	1996-01-19	1999-11-23	Pfizer Inc.	NK-1 receptor antagonists for the treatment of cancer

1996
- 1996-06-04 TW TW085106675A patent/TW340842B/zh active
- 1996-06-10 JP JP09510015A patent/JP3084069B2/ja not_active Expired - Fee Related
- 1996-06-10 TN TNTNSN96107A patent/TNSN96107A1/fr unknown
- 1996-06-10 EP EP01108350A patent/EP1114817B1/fr not_active Expired - Lifetime
- 1996-06-10 CZ CZ0052198A patent/CZ297543B6/cs not_active IP Right Cessation
- 1996-06-10 PL PL96325332A patent/PL186773B1/pl not_active IP Right Cessation
- 1996-06-10 BR BR9609989A patent/BR9609989A/pt not_active Application Discontinuation
- 1996-06-10 SI SI9630670T patent/SI1114817T1/xx unknown
- 1996-06-10 MX MX9801467A patent/MX9801467A/es active IP Right Grant
- 1996-06-10 SK SK207-98A patent/SK282925B6/sk not_active IP Right Cessation
- 1996-06-10 DE DE69616817T patent/DE69616817T2/de not_active Expired - Fee Related
- 1996-06-10 AU AU57769/96A patent/AU702698B2/en not_active Ceased
- 1996-06-10 DK DK01108350T patent/DK1114817T3/da active
- 1996-06-10 ES ES96914375T patent/ES2163017T3/es not_active Expired - Lifetime
- 1996-06-10 CN CNB961965037A patent/CN1153764C/zh not_active Expired - Fee Related
- 1996-06-10 ES ES01108350T patent/ES2211684T3/es not_active Expired - Lifetime
- 1996-06-10 PT PT01108350T patent/PT1114817E/pt unknown
- 1996-06-10 DK DK96914375T patent/DK0861235T3/da active
- 1996-06-10 AT AT01108350T patent/ATE258166T1/de not_active IP Right Cessation
- 1996-06-10 CA CA002227814A patent/CA2227814C/fr not_active Expired - Fee Related
- 1996-06-10 SI SI9630374T patent/SI0861235T1/xx unknown
- 1996-06-10 RU RU98102959/04A patent/RU2152930C2/ru not_active IP Right Cessation
- 1996-06-10 PT PT96914375T patent/PT861235E/pt unknown
- 1996-06-10 EP EP96914375A patent/EP0861235B1/fr not_active Expired - Lifetime
- 1996-06-10 TR TR1998/00300T patent/TR199800300T1/xx unknown
- 1996-06-10 WO PCT/IB1996/000572 patent/WO1997008144A1/fr active IP Right Grant
- 1996-06-10 NZ NZ308207A patent/NZ308207A/en unknown
- 1996-06-10 DE DE69631390T patent/DE69631390T2/de not_active Expired - Fee Related
- 1996-06-10 KR KR1019980701310A patent/KR100288673B1/ko not_active Expired - Fee Related
- 1996-06-10 UA UA98020924A patent/UA48981C2/uk unknown
- 1996-06-10 RO RO98-00334A patent/RO119299B1/ro unknown
- 1996-06-10 HU HU9901159A patent/HU225480B1/hu not_active IP Right Cessation
- 1996-06-10 AT AT96914375T patent/ATE208377T1/de not_active IP Right Cessation
- 1996-08-15 IL IL11907896A patent/IL119078A/xx not_active IP Right Cessation
- 1996-08-20 AR ARP960104045A patent/AR006305A1/es active IP Right Grant
- 1996-08-21 PE PE1996000625A patent/PE1398A1/es not_active Application Discontinuation
- 1996-08-21 PE PE2001000276A patent/PE20010700A1/es not_active Application Discontinuation
- 1996-08-21 DZ DZ960130A patent/DZ2086A1/fr active
- 1996-08-22 HR HR960386A patent/HRP960386B1/xx not_active IP Right Cessation
- 1996-08-23 MY MYPI96003496A patent/MY114800A/en unknown
- 1996-08-23 YU YU47896A patent/YU49122B/sh unknown
- 1996-08-23 MA MA24339A patent/MA23961A1/fr unknown
- 1996-08-24 AP APAP/P/1996/000850A patent/AP643A/en active
- 1996-08-26 CO CO96045248A patent/CO4480738A1/es unknown
1997
- 1997-12-30 IS IS4644A patent/IS1947B/is unknown
1998
- 1998-02-23 NO NO19980751A patent/NO310720B1/no unknown
- 1998-02-23 OA OA9800023A patent/OA10666A/en unknown
- 1998-02-27 BG BG102288A patent/BG64126B1/bg unknown
2000
- 2000-05-01 US US09/564,398 patent/US6506775B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
SK282925B6 (sk)	2003-01-09
CA2227814C (fr)	2002-12-31
YU49122B (sh)	2004-03-12
OA10666A (en)	2002-11-25
US6506775B1 (en)	2003-01-14
DZ2086A1 (fr)	2002-07-22
DK0861235T3 (da)	2001-12-27
SI1114817T1 (en)	2004-06-30
CA2227814A1 (fr)	1997-03-06
EP0861235B1 (fr)	2001-11-07
CO4480738A1 (es)	1997-07-09
PL325332A1 (en)	1998-07-20
KR19990044077A (ko)	1999-06-25
JPH10510554A (ja)	1998-10-13
IS1947B (is)	2004-10-13
JP3084069B2 (ja)	2000-09-04
PE1398A1 (es)	1998-02-27
TW340842B (en)	1998-09-21
PT1114817E (pt)	2004-05-31
CN1153764C (zh)	2004-06-16
AP9600850A0 (en)	1996-10-31
PE20010700A1 (es)	2001-07-09
TNSN96107A1 (fr)	2005-03-15
YU47896A (sh)	1998-12-23
MX9801467A (es)	1998-05-31
IL119078A0 (en)	1996-11-14
TR199800300T1 (xx)	1998-06-22
BG64126B1 (bg)	2004-01-30
WO1997008144A1 (fr)	1997-03-06
NO310720B1 (no)	2001-08-20
KR100288673B1 (ko)	2001-05-02
AP643A (en)	1998-04-24
IS4644A (is)	1997-12-30
AU5776996A (en)	1997-03-19
PT861235E (pt)	2002-03-28
HK1014935A1 (en)	1999-10-08
UA48981C2 (uk)	2002-09-16
CN1193961A (zh)	1998-09-23
ATE208377T1 (de)	2001-11-15
DK1114817T3 (da)	2004-04-26
SK20798A3 (en)	1999-03-12
SI0861235T1 (en)	2002-04-30
AU702698B2 (en)	1999-03-04
NZ308207A (en)	1998-07-28
MA23961A1 (fr)	1997-04-01
NO980751D0 (no)	1998-02-23
AR006305A1 (es)	1999-08-25
BG102288A (en)	1998-09-30
DE69631390T2 (de)	2004-11-25
EP1114817B1 (fr)	2004-01-21
HU225480B1 (en)	2006-12-28
DE69631390D1 (de)	2004-02-26
HRP960386B1 (en)	2002-04-30
CZ52198A3 (cs)	1999-01-13
MY114800A (en)	2003-01-31
HUP9901159A3 (en)	2000-05-29
BR9609989A (pt)	1999-07-06
ES2211684T3 (es)	2004-07-16
DE69616817D1 (de)	2001-12-13
EP1114817A1 (fr)	2001-07-11
ES2163017T3 (es)	2002-01-16
HUP9901159A2 (hu)	1999-07-28
HRP960386A2 (en)	1998-04-30
DE69616817T2 (de)	2002-04-04
NO980751L (no)	1998-02-23
ATE258166T1 (de)	2004-02-15
RO119299B1 (ro)	2004-07-30
CZ297543B6 (cs)	2007-02-07
PL186773B1 (pl)	2004-02-27
EP0861235A1 (fr)	1998-09-02
RU2152930C2 (ru)	2000-07-20

Publication	Publication Date	Title
IL119078A (en)	2003-11-23	Substituted benzylaminopiperidine compounds and pharmaceutical compositions comprising them
HU9601698D0 (en)	1996-08-28	Pharmaceutical composition
IL122618A0 (en)	1998-08-16	Substituted imidazolylacetonitrile compounds their preparation and pharmaceutical compositions containing them
AP9701160A0 (en)	1998-01-31	Compounds and pharmaceutical compositions containing them
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GB9513972D0 (en)	1995-09-06	Pharmaceutical compositions
ZA961051B (en)	1996-09-11	Pharmaceutical composition
ZA9610426B (en)	1997-06-23	Pharmaceutical composition
ZA964193B (en)	1996-12-04	Pharmaceutical composition
HUP9802291A3 (en)	1999-06-28	Penicillaminamide derivatives and pharmaceutical compositions containing them
ZA968616B (en)	1997-05-13	Pharmaceutical composition
ZA963591B (en)	1996-11-19	Pharmaceutical composition
HUP9802072A3 (en)	2000-01-28	Benzothiopyranoindazole derivatives and pharmaceutical compositions containing them
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ZA95736B (en)	1995-10-04	Pharmaceutical composition
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Legal Events

Date	Code	Title
2004-05-12	FF	Patent granted
2004-06-01	KB	Patent renewed
2006-10-04	KB	Patent renewed
2011-04-28	MM9K	Patent not in force due to non-payment of renewal fees