IL129653A - Substituted amylose as a matrix for sustained drug release - Google Patents
Substituted amylose as a matrix for sustained drug releaseInfo
- Publication number
- IL129653A IL129653A IL12965397A IL12965397A IL129653A IL 129653 A IL129653 A IL 129653A IL 12965397 A IL12965397 A IL 12965397A IL 12965397 A IL12965397 A IL 12965397A IL 129653 A IL129653 A IL 129653A
- Authority
- IL
- Israel
- Prior art keywords
- matrix
- sustained release
- amylose
- drug
- drug release
- Prior art date
Links
- 229920000856 Amylose Polymers 0.000 title abstract 4
- 239000011159 matrix material Substances 0.000 title abstract 4
- 238000013269 sustained drug release Methods 0.000 title 1
- 229940079593 drug Drugs 0.000 abstract 3
- 239000000843 powder Substances 0.000 abstract 3
- 238000013268 sustained release Methods 0.000 abstract 3
- 239000012730 sustained-release form Substances 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 239000004593 Epoxy Substances 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- -1 halogen alkane Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000007939 sustained release tablet Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/739,539 US5879707A (en) | 1996-10-30 | 1996-10-30 | Substituted amylose as a matrix for sustained drug release |
| PCT/CA1997/000792 WO1998018451A2 (fr) | 1996-10-30 | 1997-10-22 | Amylose substituee servant de matrice pour la liberation continue de medicaments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL129653A0 IL129653A0 (en) | 2000-02-29 |
| IL129653A true IL129653A (en) | 2005-06-19 |
Family
ID=24972771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12965397A IL129653A (en) | 1996-10-30 | 1997-10-22 | Substituted amylose as a matrix for sustained drug release |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5879707A (fr) |
| EP (1) | EP0938300B1 (fr) |
| JP (1) | JP4477144B2 (fr) |
| CN (1) | CN1122535C (fr) |
| AT (1) | ATE249814T1 (fr) |
| AU (1) | AU719190B2 (fr) |
| BR (2) | BRPI9712618B1 (fr) |
| CA (1) | CA2271895C (fr) |
| DE (1) | DE69724987T2 (fr) |
| ES (1) | ES2207720T3 (fr) |
| HU (1) | HU225037B1 (fr) |
| IL (1) | IL129653A (fr) |
| WO (1) | WO1998018451A2 (fr) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999029310A2 (fr) * | 1997-12-05 | 1999-06-17 | Medical College Of Georgia Research Institute, Inc. | Regulation de l'immunite a mediation lymphocytaire, au moyen du tryptophane |
| US6284273B1 (en) * | 1998-02-24 | 2001-09-04 | Vincent Lenaerts | Cross-linked high amylose starch resistant to amylase as a matrix for the slow release of biologically active compounds |
| US6299907B1 (en) * | 1998-06-12 | 2001-10-09 | Kansas State University Research Foundation | Reversibly swellable starch products |
| US6607748B1 (en) | 2000-06-29 | 2003-08-19 | Vincent Lenaerts | Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture |
| EP1174127A1 (fr) * | 2000-07-21 | 2002-01-23 | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno | Composition pour la libération ciblée d' un principe actif et procédé pour la préparation d' une telle composition |
| EP1485078B1 (fr) * | 2002-03-15 | 2012-09-26 | Cypress Bioscience, Inc. | Milnacipran pour le traitement du syndrôme du colon irritable |
| US8487002B2 (en) * | 2002-10-25 | 2013-07-16 | Paladin Labs Inc. | Controlled-release compositions |
| US20060003004A1 (en) * | 2002-10-25 | 2006-01-05 | Collegium Pharmaceutical, Inc. | Pulsatile release compositions of milnacipran |
| TWI319713B (en) * | 2002-10-25 | 2010-01-21 | Sustained-release tramadol formulations with 24-hour efficacy | |
| US20040121010A1 (en) * | 2002-10-25 | 2004-06-24 | Collegium Pharmaceutical, Inc. | Pulsatile release compositions of milnacipran |
| US20040228830A1 (en) * | 2003-01-28 | 2004-11-18 | Collegium Pharmaceutical, Inc. | Multiparticulate compositions of milnacipran for oral administration |
| US7598287B2 (en) | 2003-04-01 | 2009-10-06 | Medical College Of Georgia Research Institute, Inc. | Use of inhibitors of indoleamine-2,3-dioxygenase in combination with other therapeutic modalities |
| US20050186289A1 (en) * | 2003-04-01 | 2005-08-25 | Medical College Of Georgia Research Institute, Inc. | Regulation of T cell-mediated immunity by D isomers of inhibitors of indoleamine-2,3-dioxygenase |
| US20060172006A1 (en) * | 2003-10-10 | 2006-08-03 | Vincent Lenaerts | Sustained-release tramadol formulations with 24-hour clinical efficacy |
| CA2491665A1 (fr) * | 2004-12-24 | 2006-06-24 | Louis Cartilier | Formulation de comprime pour liberation soutenue de principe actif |
| ES2620293T3 (es) * | 2005-09-09 | 2017-06-28 | Paladin Labs Inc. | Composición de liberación sostenida de fármacos |
| AU2006308449B8 (en) * | 2005-09-09 | 2012-11-22 | Angelini Labopharm, Llc | Trazodone composition for once a day administration |
| ATE454908T1 (de) * | 2005-09-21 | 2010-01-15 | Surmodics Inc | In situ okklusionszusammensetzungen mit natürlichen biologisch abbaubaren polysacchariden |
| ATE540705T1 (de) * | 2005-09-21 | 2012-01-15 | Surmodics Inc | Überzüge und artikel mit natürlichen biologisch abbaubaren polysacchariden |
| AU2006306521B2 (en) * | 2005-10-21 | 2011-12-22 | Medical College Of Georgia Research Institute, Inc. | The induction of indoleamine 2,3-dioxygenase in dendritic cells by TLR ligands and uses thereof |
| WO2007055329A1 (fr) * | 2005-11-11 | 2007-05-18 | Asahi Kasei Chemicals Corporation | Preparation solide a liberation controlee |
| JP5819579B2 (ja) * | 2006-01-13 | 2015-11-24 | サーモディクス,インコーポレイティド | 薬物送達のためのマトリックスを含む微粒子 |
| EP2296630A2 (fr) * | 2008-05-07 | 2011-03-23 | SurModics, Inc. | Administration de complexe d'acide nucléique à partir de particules |
| US8901092B2 (en) | 2010-12-29 | 2014-12-02 | Surmodics, Inc. | Functionalized polysaccharides for active agent delivery |
| WO2015127537A1 (fr) * | 2014-02-27 | 2015-09-03 | B-Organic Films Corp. | Agents bio-actifs inclus dans l'amidon fonctionnalisé ayant une structure en v à hélice unique |
| CN104291973B (zh) * | 2014-09-26 | 2016-08-24 | 广州市高士实业有限公司 | 缓释载体及其在盆栽作物所需水分或肥料的缓释中的应用 |
| CN108450545B (zh) * | 2018-04-12 | 2021-08-13 | 天津商业大学 | 利用回生淀粉制备果蔬保鲜剂 |
| CN114196076B (zh) * | 2021-12-31 | 2023-04-28 | 昆山京昆油田化学科技有限公司 | 一种起泡胶及其制备方法和凝胶材料 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3034911A (en) * | 1959-03-25 | 1962-05-15 | Nat Starch Chem Corp | Tablet disintegrants |
| US3163579A (en) * | 1962-02-15 | 1964-12-29 | Nat Starch Chem Corp | Method for the entrapment of choline salts |
| GB978495A (en) * | 1962-07-25 | 1964-12-23 | Staley Mfg Co A E | Amylose solutions |
| US3490742A (en) * | 1966-01-14 | 1970-01-20 | Staley Mfg Co A E | Compressed tablets |
| US3622677A (en) * | 1969-07-07 | 1971-11-23 | Staley Mfg Co A E | Compressed tablets containing compacted starch as binder-disintegrant ingredient |
| US4072535A (en) * | 1970-12-28 | 1978-02-07 | A. E. Staley Manufacturing Company | Precompacted-starch binder-disintegrant-filler material for direct compression tablets and dry dosage capsules |
| JPS4837817B1 (fr) * | 1970-12-31 | 1973-11-14 | ||
| JPS5945002B2 (ja) * | 1974-06-08 | 1984-11-02 | ユニチカ株式会社 | カルボキシアルキル化アミロ−スペレツトの製造法 |
| DE3045135A1 (de) * | 1980-11-29 | 1982-06-09 | Sandoz-Patent-GmbH, 7850 Lörrach | Pharmazeutische kompositionen enthaltende bioabbaubare polymere |
| US4369308A (en) * | 1981-07-24 | 1983-01-18 | National Starch And Chemical Corporation | Low swelling starches as tablet disintegrants |
| US4985082A (en) * | 1987-11-20 | 1991-01-15 | Lafayette Applied Chemistry, Inc. | Microporous granular starch matrix compositions |
| GB8812490D0 (en) * | 1988-05-26 | 1988-06-29 | Agricultural & Food Res | Delayed release formulations |
| CA2041774C (fr) * | 1990-11-27 | 1994-04-19 | Mircea A. Mateescu | Utilisation d'amylose reticulee en tant que matrice pour la liberation lente de composes biologiquement actifs |
| CA2032385A1 (fr) * | 1990-12-17 | 1992-06-18 | Chung Wai-Chiu | Amidons debranches par un enzyme sous forme de comprimes |
| AU4109493A (en) * | 1992-04-20 | 1993-11-18 | Bruce K. Redding Jr. | Method and apparatus for the modification of starch and other polymers |
| NL9201195A (nl) * | 1992-07-03 | 1994-02-01 | Tno | Preparaat voor de gereguleerde afgifte van een werkzame stof en werkwijze ter bereiding van een dergelijk preparaat. |
| DE69302580T2 (de) * | 1992-07-24 | 1996-09-26 | Labopharm Inc., Ste-Therese, Quebec | Vernetztes polyhydroxyl-material zur enzymatisch gesteuerten arzneistofffreisetzung |
| US5616343A (en) * | 1993-03-25 | 1997-04-01 | Labopharm, Inc. | Cross-linked amylose as a binder/disintegrant in tablets |
-
1996
- 1996-10-30 US US08/739,539 patent/US5879707A/en not_active Expired - Lifetime
-
1997
- 1997-10-22 JP JP51983798A patent/JP4477144B2/ja not_active Expired - Lifetime
- 1997-10-22 HU HU0000256A patent/HU225037B1/hu not_active IP Right Cessation
- 1997-10-22 CN CN97199353A patent/CN1122535C/zh not_active Expired - Fee Related
- 1997-10-22 DE DE69724987T patent/DE69724987T2/de not_active Expired - Lifetime
- 1997-10-22 AU AU47689/97A patent/AU719190B2/en not_active Ceased
- 1997-10-22 WO PCT/CA1997/000792 patent/WO1998018451A2/fr active IP Right Grant
- 1997-10-22 EP EP97910175A patent/EP0938300B1/fr not_active Expired - Lifetime
- 1997-10-22 BR BRPI9712618-7A patent/BRPI9712618B1/pt unknown
- 1997-10-22 IL IL12965397A patent/IL129653A/xx not_active IP Right Cessation
- 1997-10-22 CA CA002271895A patent/CA2271895C/fr not_active Expired - Fee Related
- 1997-10-22 AT AT97910175T patent/ATE249814T1/de not_active IP Right Cessation
- 1997-10-22 ES ES97910175T patent/ES2207720T3/es not_active Expired - Lifetime
- 1997-10-22 BR BRPI9712618-7A patent/BR9712618B1/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69724987D1 (de) | 2003-10-23 |
| WO1998018451A3 (fr) | 1998-08-06 |
| US5879707A (en) | 1999-03-09 |
| JP2001502700A (ja) | 2001-02-27 |
| BR9712618A (pt) | 1999-12-21 |
| CA2271895C (fr) | 2002-08-20 |
| AU719190B2 (en) | 2000-05-04 |
| ATE249814T1 (de) | 2003-10-15 |
| BR9712618B1 (pt) | 2008-11-18 |
| CN1122535C (zh) | 2003-10-01 |
| DE69724987T2 (de) | 2004-07-15 |
| CN1235539A (zh) | 1999-11-17 |
| WO1998018451A2 (fr) | 1998-05-07 |
| JP4477144B2 (ja) | 2010-06-09 |
| HU225037B1 (en) | 2006-05-29 |
| BRPI9712618B1 (pt) | 2009-07-21 |
| AU4768997A (en) | 1998-05-22 |
| HUP0000256A2 (hu) | 2000-06-28 |
| HUP0000256A3 (en) | 2000-08-28 |
| EP0938300A2 (fr) | 1999-09-01 |
| ES2207720T3 (es) | 2004-06-01 |
| EP0938300B1 (fr) | 2003-09-17 |
| IL129653A0 (en) | 2000-02-29 |
| CA2271895A1 (fr) | 1998-05-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |