JP2001190560A - Ovum collection needle and washing and absorbing ovum collection device using the same - Google Patents
Ovum collection needle and washing and absorbing ovum collection device using the sameInfo
- Publication number
- JP2001190560A JP2001190560A JP2000001278A JP2000001278A JP2001190560A JP 2001190560 A JP2001190560 A JP 2001190560A JP 2000001278 A JP2000001278 A JP 2000001278A JP 2000001278 A JP2000001278 A JP 2000001278A JP 2001190560 A JP2001190560 A JP 2001190560A
- Authority
- JP
- Japan
- Prior art keywords
- needle
- egg
- outer needle
- washing
- inner needle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000005406 washing Methods 0.000 title claims abstract description 32
- 102000002322 Egg Proteins Human genes 0.000 title abstract 8
- 108010000912 Egg Proteins Proteins 0.000 title abstract 8
- 210000004681 ovum Anatomy 0.000 title abstract 8
- 239000007788 liquid Substances 0.000 claims abstract description 38
- 229920003002 synthetic resin Polymers 0.000 claims abstract description 8
- 239000000057 synthetic resin Substances 0.000 claims abstract description 8
- 238000004140 cleaning Methods 0.000 claims description 18
- 238000002347 injection Methods 0.000 claims description 17
- 239000007924 injection Substances 0.000 claims description 17
- 238000004891 communication Methods 0.000 claims description 7
- 229920005989 resin Polymers 0.000 claims description 7
- 239000011347 resin Substances 0.000 claims description 7
- 230000036760 body temperature Effects 0.000 claims description 3
- 239000012530 fluid Substances 0.000 claims description 3
- 238000007789 sealing Methods 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 230000002745 absorbent Effects 0.000 claims 1
- 239000002250 absorbent Substances 0.000 claims 1
- 238000005070 sampling Methods 0.000 abstract 1
- 235000013601 eggs Nutrition 0.000 description 68
- 238000000034 method Methods 0.000 description 10
- 239000000523 sample Substances 0.000 description 5
- 210000003815 abdominal wall Anatomy 0.000 description 3
- 238000000338 in vitro Methods 0.000 description 3
- 229920000954 Polyglycolide Polymers 0.000 description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 description 2
- 208000000509 infertility Diseases 0.000 description 2
- 230000036512 infertility Effects 0.000 description 2
- 231100000535 infertility Toxicity 0.000 description 2
- 238000002350 laparotomy Methods 0.000 description 2
- 229920000747 poly(lactic acid) Polymers 0.000 description 2
- -1 polyethylene Polymers 0.000 description 2
- 239000004633 polyglycolic acid Substances 0.000 description 2
- 239000004626 polylactic acid Substances 0.000 description 2
- 229920002635 polyurethane Polymers 0.000 description 2
- 239000004814 polyurethane Substances 0.000 description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 229920000106 Liquid crystal polymer Polymers 0.000 description 1
- 239000004977 Liquid-crystal polymers (LCPs) Substances 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010034238 Pelvic adhesions Diseases 0.000 description 1
- 239000004695 Polyether sulfone Substances 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 230000004720 fertilization Effects 0.000 description 1
- 238000002695 general anesthesia Methods 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 238000012966 insertion method Methods 0.000 description 1
- 238000002690 local anesthesia Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910001000 nickel titanium Inorganic materials 0.000 description 1
- 210000001672 ovary Anatomy 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920006393 polyether sulfone Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
Landscapes
- Surgical Instruments (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
Description
【０００１】[0001]
【発明の属する技術分野】本発明は、体外受精並びに顕
微受精を行うために、ヒト並びに動物の卵巣から卵を吸
引採取するために用いられる採卵針に関するもので、一
般に、超音波プローブにマウントされ、超音波エコー下
で使用される。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an egg collection needle used for aspirating and collecting eggs from the ovaries of humans and animals for performing in vitro fertilization and microinsemination, and is generally mounted on an ultrasonic probe. Used under ultrasound echo.
【０００２】[0002]
【従来の技術】不妊症治療の方法として、従来、体外受
精−胚移植（ＩＶＦ−ＥＴ）が行われているが、ＩＶＦ
−ＥＴの成否のひとつは成熟卵を如何にして得るかとい
うことにある。最初の採卵の報告は、1966年にエドワー
ズ（Edwards）によってなされた開腹によるもので、197
0年には、さらに侵襲の少ない方法として、エドワーズ
等により腹腔鏡を用いた採卵が報告されている。この方
法は開腹による方法と異なり、採卵を繰り返し行うこと
ができるという利点があるが、ＩＶＦ−ＥＴを必要とす
る患者には強度の骨盤癒着の者が少なからず存在してお
り、このような患者には腹腔鏡による方法を採用するこ
とができない。また、腹腔鏡による方法は、全身麻酔を
必要とする侵襲性のある方法である。そこで、スエーデ
ンとデンマークの2つのグループにより、ＩＶＦ−ＥＴ
における超音波採卵が開発され、１９８２年には、超音
波採卵による始めての体外受精児が誕生している。超音
波採卵によるＩＶＦ−ＥＴは、採卵率が腹腔鏡採卵と遜
色が無く、また、画像超音波スキャナーは階調性に優れ
た高分解能を有しているため、正確な穿刺方法を提供で
きる上、侵襲性も少ない。そのため、超音波採卵は、世
界の多くの先進的なＩＶＦ−ＥＴのグループによって採
用され、その後の技術の進歩も預かって、中心的不妊治
療法として広く受け入れられるようになっている2. Description of the Related Art In vitro fertilization-embryo transfer (IVF-ET) has been conventionally used as a method of treating infertility.
One of the successes of ET is how to get mature eggs. The first report of egg collection was due to a laparotomy made by Edwards in 1966,
In year 0, laparoscopic egg collection was reported by Edwards et al. As a less invasive method. This method has the advantage that, unlike the method based on laparotomy, eggs can be repeatedly collected. However, there are not a few patients who require IVF-ET who have strong pelvic adhesions. Cannot use the laparoscopic method. The laparoscopic method is an invasive method requiring general anesthesia. Therefore, two groups, Sweden and Denmark, have signed the IVF-ET
In 1982, the first in vitro fertilized infant by ultrasonic egg collection was born. The IVF-ET using ultrasonic egg collection has an egg collection rate comparable to that of laparoscopic egg collection, and the image ultrasonic scanner has a high resolution with excellent gradation and can provide an accurate puncture method. , Less invasive. As such, ultrasonic egg harvesting has been adopted by many advanced IVF-ET groups around the world and has become widely accepted as a central infertility treatment, with subsequent technological advances.
【０００３】超音波採卵は、針の挿入方法の違いによ
り、腹壁プローブを用いた経膀胱的採卵法、腹壁プロー
ブまたは経膣プローブを用いた経膣採卵法、腹壁プロー
ブを用いた経尿道採卵法に分類され、現在では、穿刺距
離が短く皮膚を傷つけない、局所麻酔が有効などの理由
から、経膣的方法が超音波採卵で最も良く採用されてい
る。超音波採卵は、当初、シングルニードルの超音波針
を卵胞に穿刺し、シリンジで洗浄液を注入し、その後、
別のシリンジで吸引して卵を採取する操作を繰り返すこ
とにより行われていた。しかしながら、この方法は、シ
リンジを差し替える操作の間に、刃先が振れたり、液の
逆流が生じたりするため、採取に要する時間が長くな
り、また採卵率も悪かった。そこで、図６および図７に
示す洗浄吸引採卵装置におけるような、その外面に長手
軸方向の溝１０３が設けられた中空の内針１０と、この
内針１０に外挿された外針２０からなり、外針２０と溝
１０３の間に形成されるルーメン２０３と内針２０のル
ーメン１０４を有する、所謂ダブルルーメンの採卵針が
登場し、術者が採卵針を穿刺した卵胞の卵を確認し、補
助者がシリンジにて洗浄液を注入しながら吸引を行うこ
とができるようになり、採卵時間も採卵率も向上してい
る。尚、図中、４０はコネクター、５０は卵吸引ライ
ン、６０は洗浄液注入ライン、７０は採卵容器である。[0003] Ultrasonic egg collection includes transvesical egg collection using an abdominal wall probe, transvaginal egg collection using an abdominal wall probe or a transvaginal probe, and transurethral egg collection using an abdominal wall probe, depending on the needle insertion method. At present, the transvaginal method is most often used in ultrasonic egg collection because of its short puncture distance, which does not damage the skin, and effective local anesthesia. Ultrasonic egg collection, initially, puncture the follicle with a single needle ultrasonic needle, inject the washing solution with a syringe,
It has been performed by repeating the operation of collecting eggs by sucking with another syringe. However, according to this method, the blade edge swings or the liquid flows backward during the operation of replacing the syringe, so that the time required for collection is long and the egg collection rate is poor. Therefore, as in the washing and suction egg collecting apparatus shown in FIGS. 6 and 7, a hollow inner needle 10 having a longitudinal groove 103 on its outer surface and an outer needle 20 externally inserted into the inner needle 10 are provided. In other words, a so-called double-lumen egg collection needle having a lumen 203 formed between the outer needle 20 and the groove 103 and a lumen 104 of the inner needle 20 appears, and the operator confirms the egg of the follicle punctured by the needle. In addition, the assistant can perform suction while injecting the washing liquid with the syringe, and the egg collection time and the egg collection rate are improved. In the figure, 40 is a connector, 50 is an egg suction line, 60 is a washing liquid injection line, and 70 is an egg collection container.
【０００４】[0004]
【発明が解決しようとする課題】しかしながら、従来の
ダブルルーメン採卵針の場合、洗浄液ルートは採卵ルー
トを縮小させることにより成り立っているので、採卵ル
ートを確保するためには、洗浄液ルートの面積を狭くす
る必要があり、洗浄液ルートを狭くすると、今度は管路
抵抗が大きくなるため、シリンジでの注入に大きな力を
必要とするなど問題があった。本発明は上記の事情に鑑
みてなされたもので、採卵ルートの内径を卵子が通過で
きる大きさに確保するとともに、洗浄ルートの流量も十
分に確保できる採卵針を提供することを目的とする。ま
た、この採卵針を用いた洗浄吸引採卵装置を提供するこ
とを目的とする。However, in the case of the conventional double-lumen egg collection needle, since the washing liquid route is formed by reducing the egg collecting route, the area of the washing liquid route must be reduced in order to secure the egg collecting route. If the cleaning solution route is narrowed, the resistance of the pipeline will increase, which causes a problem that a large force is required for injection with a syringe. The present invention has been made in view of the above circumstances, and an object of the present invention is to provide an egg collecting needle that secures the inside diameter of an egg collecting route to a size that allows an egg to pass through and also ensures a sufficient flow rate of a washing route. It is another object of the present invention to provide a washing suction egg collecting apparatus using the egg collecting needle.
【０００５】[0005]
【課題を解決するための手段】本発明者等は、上記の課
題を解決するために鋭意検討の結果、採卵針を、合成樹
脂製の外針と剛性を有する内針で構成し、外針の先端部
に内針の先端部と密着する絞り部を形成するとともに、
この絞り部に対応する内針の外面に洗浄液流通用の長手
方向の溝を設ければ良いことに想到し、本発明を完成し
た。すなわち本発明は、合成樹脂製の中空の外針と、該
外針にその先端部を所定長突出させて挿着された、先端
に刃先が設けられた中空の剛性を有する内針と、前記外
針および内針の基端部をそれぞれ固定する手段を備えた
分岐コネクター、とを含み、前記外針の先端部に前記内
針の先端部と密着する絞り部が形成されるとともに、該
絞り部に対応する前記内針の外表面に洗浄液流通用の長
手方向の溝が設けられてなる採卵針に関する（第１発
明）。ここで、外針は、吸水性樹脂あるいは体温付近の
温度で軟化する形状記憶樹脂で形成されるのが好まし
い。また、本発明は、請求項１に記載の採卵針と、該採
卵針の基端部分で、それぞれ内針の内腔および外針の内
腔と液体連通するように接続された、卵採取容器を備え
た卵吸引ラインおよび、バルーンと該バルーンを密封す
るシェルからなるポンプ手段を備えた洗浄液注入ライン
を含み、該卵吸引ラインと洗浄液注入ラインが流路切替
手段を介して接続されてなる洗浄吸引採卵装置に関する
（第２発明）。ここで、必要ならば、流路切替手段には
予備吸引ラインを接続してもよい。Means for Solving the Problems The present inventors have made intensive studies to solve the above-mentioned problems, and as a result, the egg collecting needle is constituted by an outer needle made of synthetic resin and an inner needle having rigidity. At the tip of the needle, while forming a narrowed portion that is in close contact with the tip of the inner needle,
The present inventor has completed the present invention by conceiving that it is sufficient to provide a longitudinal groove for distributing the cleaning liquid on the outer surface of the inner needle corresponding to the throttle portion. That is, the present invention provides a hollow outer needle made of a synthetic resin, a hollow rigid inner needle having a cutting edge provided at the tip inserted into the outer needle with its tip protruding a predetermined length. A branch connector having means for fixing the proximal ends of the outer needle and the inner needle, respectively, and a throttle portion that is in close contact with the distal end of the inner needle is formed at the distal end of the outer needle; A first aspect of the present invention relates to an egg collection needle in which a longitudinal groove for circulating a washing liquid is provided on an outer surface of the inner needle corresponding to a part (first invention). Here, the outer needle is preferably formed of a water-absorbing resin or a shape memory resin that softens at a temperature near body temperature. Further, the present invention provides an egg collection needle according to claim 1, and an egg collection container connected at the base end portion of the egg collection needle so as to be in fluid communication with the lumen of the inner needle and the lumen of the outer needle, respectively. And a washing liquid injection line provided with a pump means comprising a balloon and a shell for sealing the balloon, wherein the egg suction line and the washing liquid injection line are connected via flow path switching means. The present invention relates to a suction egg collecting apparatus (second invention). Here, if necessary, a preliminary suction line may be connected to the flow path switching means.
【０００６】[0006]
【発明の実施の形態】次に本発明の実施例について図面
に基づいて説明する。図１は本発明の実施例を示す平面
図であり、図2は図１の先端部の拡大縦断面図、図３は
図１のＸ−Ｘ線拡大断面図、図４は図１の基端部の拡大
縦断面図である。また、図５は図１に示す採卵針を利用
した洗浄吸引採卵装置を示す平面図である。先ず、採卵
針について説明する。本発明の採卵針は、図１〜４に示
すように、合成樹脂製の外針１と、この外針１に挿着さ
れた、先端に刃先２２が設けられた剛性を有する内針２
と、外針１および内針２の基端部をそれぞれ固定する分
岐コネクター３とを含んでおり、外針１の先端部には、
内針２の先端部と密着する絞り部１２が形成され、この
絞り部１２に対応する内針２の外表面には、洗浄液流通
用の長手方向の溝２３が設けられている。DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Next, embodiments of the present invention will be described with reference to the drawings. FIG. 1 is a plan view showing an embodiment of the present invention, FIG. 2 is an enlarged longitudinal sectional view of a tip portion of FIG. 1, FIG. 3 is an enlarged sectional view taken along line XX of FIG. 1, and FIG. It is an expanded longitudinal sectional view of an end part. FIG. 5 is a plan view showing a washing suction egg collecting apparatus using the egg collecting needle shown in FIG. First, the egg collection needle will be described. As shown in FIGS. 1 to 4, the egg collecting needle of the present invention comprises an outer needle 1 made of a synthetic resin, and a rigid inner needle 2 having a cutting edge 22 provided at the tip thereof, which is inserted into the outer needle 1.
And a branch connector 3 for fixing the proximal ends of the outer needle 1 and the inner needle 2 respectively.
A narrowed portion 12 that is in close contact with the tip of the inner needle 2 is formed, and a longitudinal groove 23 for distributing the cleaning liquid is provided on the outer surface of the inner needle 2 corresponding to the narrowed portion 12.
【０００７】外針１は合成樹脂で形成された柔軟なチュ
ーブであり、基端にハブ１１を備え、先端部は絞られて
内針１の先端部と密着する絞り部１２に形成されてい
る。外針１を形成する合成樹脂としては、例えば、ポリ
エチレンや、ポリエステル、ポリウレタン、シリコー
ン、フッ素樹脂、ポリビニルアルコール、ポリグリコー
ル酸、ポリ乳酸等の可撓性樹脂や、体温付近の温度で軟
化するポリウレタン系形状記憶樹脂等が挙げられるが、
洗浄液注入時にチューブが膨張して流路が拡大するとい
う特性から、形状記憶樹脂や、水分を吸収して軟化する
性質を有するポリビニルアルコールやポリグリコール
酸、ポリ乳酸等が好ましい。外針１のハブ１１は、図１
や図４に示すような分岐コネクター３の先端部であって
もよいが、図示していないが、ハブを別途設けてこれを
分岐コネクターと接続できるようにしてもよい。外針１
の内径は内針２の外径より大きく形成されており、外針
１の内腔１と内針２の外表面の間は洗浄液流通路４にな
っている。尚、図４において、１３は外針１をハブ１１
に固定するためのカシメ部材であるThe outer needle 1 is a flexible tube made of a synthetic resin, has a hub 11 at the base end, and is formed at a narrowed portion 12 which is narrowed at the distal end and is in close contact with the distal end of the inner needle 1. . Examples of the synthetic resin forming the outer needle 1 include a flexible resin such as polyethylene, polyester, polyurethane, silicone, fluororesin, polyvinyl alcohol, polyglycolic acid, and polylactic acid, and a polyurethane that softens at a temperature near body temperature. System shape resin, etc.,
A shape memory resin, polyvinyl alcohol, polyglycolic acid, polylactic acid, or the like, which has a property of absorbing water and softening when water is injected, is preferable because the tube expands and the flow path expands when the cleaning liquid is injected. The hub 11 of the outer needle 1 is shown in FIG.
Alternatively, a hub may be provided separately, though not shown, such that the hub can be connected to the branch connector, although not shown. Outer needle 1
Is formed larger than the outer diameter of the inner needle 2, and a cleaning liquid flow passage 4 is formed between the inner cavity 1 of the outer needle 1 and the outer surface of the inner needle 2. In FIG. 4, reference numeral 13 denotes the outer needle 1 connected to the hub 11.
It is a caulking member for fixing to
【０００８】内針２はステンレス、ニッケル−チタン合
金等の金属や、ポリエーテルスルホン、液晶ポリマー等
の可撓性合成樹脂で形成された剛性を有するパイプであ
り、先端に刃先２２を有し、基端にハブ２１を備えてい
る。内針２は、刃先２２とライジスタンスに相当する部
分が突出するように外針１に挿着されており、外針１の
絞り部１２に対応する位置の外表面には、洗浄液流通用
の長手方向の溝２３が設けられている。この溝２３は、
図２に示すように、先端方向も基端方向も外針１の絞り
部１２より長く形成されており、洗浄液流通路４を流れ
てきた洗浄液はこの溝２３を通って洗浄部位に注入され
る。溝２３の数は、限定するものではないが、通常２〜
６個である。内針２のハブ２１は、図１や図４に示すよ
うな、分岐コネクターの基端部と接続できるようにした
ものであってもよいが、図示していないが、分岐コネク
ター３の先端部をハブとしたものであってもよい。The inner needle 2 is a rigid pipe formed of a metal such as stainless steel or a nickel-titanium alloy, or a flexible synthetic resin such as polyether sulfone or liquid crystal polymer. A hub 21 is provided at the base end. The inner needle 2 is inserted into the outer needle 1 so that a portion corresponding to the cutting edge 22 and the ridge is protruded, and the outer surface of the outer needle 1 at a position corresponding to the squeezed portion 12 is provided with a cleaning liquid flow passage. A longitudinal groove 23 is provided. This groove 23
As shown in FIG. 2, both the distal end direction and the proximal end direction are formed to be longer than the narrowed portion 12 of the outer needle 1, and the cleaning liquid flowing through the cleaning liquid flow path 4 is injected into the cleaning portion through the groove 23. . Although the number of the grooves 23 is not limited, it is usually 2 to
There are six. The hub 21 of the inner needle 2 may be such that it can be connected to the base end of the branch connector as shown in FIGS. 1 and 4; May be used as a hub.
【０００９】分岐コネクター３は、図４に示すような形
状に限定されるものではないが、少なくとも、図５に示
すような、内針２および外針１を固定する手段と、内針
２の内腔２４と卵吸引ライン６を液体連通させる手段
と、外針１の内腔１４と洗浄液注入ライン６を液体連通
させる手段を備えている。例えば、図４で言えば、内針
２および外針１を固定する手段は、分岐コネクター３の
先端部（ハブ１１）および内針ハブ固定部３２であり、
内針２の内腔２４と卵吸引ライン６を液体連通させる手
段は洗浄液注入ライン接続部３１であり、外針１の内腔
１４と洗浄液注入ライン６を液体連通させる手段は内針
ハブ固定部３２（これに固定されたハブ２１を介して内
針２の内腔２４と卵吸引ライン６が接続されている）で
ある。The branch connector 3 is not limited to the shape as shown in FIG. 4, but at least means for fixing the inner needle 2 and the outer needle 1 as shown in FIG. There is provided a means for liquid communication between the lumen 24 and the egg suction line 6, and a means for liquid communication between the lumen 14 of the outer needle 1 and the washing liquid injection line 6. For example, in FIG. 4, the means for fixing the inner needle 2 and the outer needle 1 are the distal end portion (hub 11) of the branch connector 3 and the inner needle hub fixing portion 32,
The means for liquid communication between the lumen 24 of the inner needle 2 and the egg suction line 6 is a washing liquid injection line connecting part 31, and the means for liquid communication between the lumen 14 of the outer needle 1 and the washing liquid injection line 6 is an inner needle hub fixing part 32 (the lumen 24 of the inner needle 2 and the egg suction line 6 are connected via the hub 21 fixed thereto).
【００１０】次に、上記の採卵針Ｎを用いた洗浄吸引採
卵装置について説明する。本発明の洗浄吸引採卵装置
は、図５に示すように、採卵針Ｎと卵吸引ライン５、洗
浄液注入ライン６を含んでなり、卵吸引ライン５と洗浄
液注入ライン６は流路切替手段としての例えば三方コッ
ク７を介して接続チューブ８で接続されている。卵吸引
ライン５は卵採取容器５１を備えたラインであり、採卵
針Ｎの基端部分で、図４に示す内針２のハブ２１に接続
され、内針２の内腔２４と液体連通している。また、洗
浄液注入ライン６はポンプ手段６４を備えたラインであ
り、採卵針Ｎの基端部分で、図４に示す分岐コネクター
３の洗浄液注入ライン接続部３１に接続され、外針１の
内腔１４、正確には外針１の内腔１と内針２の外表面の
間にできる洗浄液流通路４、と液体連通している。ポン
プ手段６４は、バルーン６４１とこのバルーン６４１を
密封するシェル６４２からなるものであり、バルーン６
４１の収縮力を利用して内部に充填された洗浄液を吐出
することができる。また、洗浄液の吐出の際、収縮した
バルーン６４１とこれを密封するシェル６４２の間には
陰圧が生じるので、三方コック７を操作して卵吸引ライ
ン５と洗浄液注入ライン６を接続すれば、この陰圧を利
用して、卵吸引ライン５に吸引力を付与し、卵の吸引を
行うことができる。洗浄液注入ライン６には、必要なら
ば流量制御手段６１やフィルター６２、クランプ６３等
を配してもよい。また、卵の吸引力が不足する場合を考
慮して、三方コック７に予備吸引ライン９を接続しても
よい。予備吸引ライン９には吸引手段としての例えば注
射器などを接続可能になっている。Next, a washing suction egg collecting apparatus using the above-mentioned egg collecting needle N will be described. As shown in FIG. 5, the washing suction egg collecting apparatus of the present invention includes an egg collecting needle N, an egg suction line 5, and a washing liquid injection line 6, and the egg sucking line 5 and the washing liquid injection line 6 serve as flow path switching means. For example, they are connected by a connection tube 8 via a three-way cock 7. The egg suction line 5 is a line provided with an egg collecting container 51, and is connected to the hub 21 of the inner needle 2 shown in FIG. ing. The washing liquid injection line 6 is a line provided with a pump means 64. The washing liquid injection line 6 is connected to the washing liquid injection line connecting portion 31 of the branch connector 3 shown in FIG. 14. More precisely, it is in fluid communication with a washing liquid flow passage 4 formed between the inner cavity 1 of the outer needle 1 and the outer surface of the inner needle 2. The pump means 64 comprises a balloon 641 and a shell 642 for sealing the balloon 641.
The cleaning liquid filled inside can be discharged using the contraction force of 41. Further, at the time of discharging the cleaning liquid, a negative pressure is generated between the deflated balloon 641 and the shell 642 that seals the balloon, so that the egg suction line 5 and the cleaning liquid injection line 6 can be connected by operating the three-way cock 7. Utilizing this negative pressure, a suction force can be applied to the egg suction line 5 to suck the eggs. If necessary, the cleaning liquid injection line 6 may be provided with a flow control means 61, a filter 62, a clamp 63, and the like. In addition, a preliminary suction line 9 may be connected to the three-way cock 7 in consideration of a case where the suction force of the egg is insufficient. For example, a syringe as a suction means can be connected to the preliminary suction line 9.
【００１１】[0011]
【発明の効果】以上説明してきたことから明らかなよう
に、本発明の採卵針では、採卵ルートである内針の内腔
を縮小させることなく、内針の外面に設けた溝を洗浄ル
ートとしているので、採卵ルートの内径を卵子が通過で
きる大きさに確保でき、また、洗浄ルートの流量も十分
に確保することができる。As is clear from the above description, in the egg collecting needle of the present invention, the groove provided on the outer surface of the inner needle is used as the washing route without reducing the inner lumen of the inner needle which is the egg collecting route. Therefore, the inside diameter of the egg collection route can be secured to a size that allows the eggs to pass, and the flow rate of the washing route can be sufficiently secured.
【図１】 本発明の一実施例を示す平面図である。FIG. 1 is a plan view showing an embodiment of the present invention.
【図２】 図１の先端部の拡大縦断面図である。FIG. 2 is an enlarged vertical sectional view of a distal end portion of FIG.
【図３】 図１のＸ−Ｘ線拡大断面図である。FIG. 3 is an enlarged sectional view taken along line XX of FIG. 1;
【図４】 図１の基端部の拡大縦断面図である。FIG. 4 is an enlarged vertical sectional view of a base end portion of FIG. 1;
【図５】 図１に示す採卵針を利用した洗浄吸引採卵装
置を示す平面図である。FIG. 5 is a plan view showing a washing suction egg collecting apparatus using the egg collecting needle shown in FIG. 1;
１ 外針 １１ ハブ １２ 絞り部 １３ カシメ部材 １４ 内腔 ２ 内針 ２１ ハブ ２２ 刃先 ２３ 溝 ２４ 内腔 ３ 分岐コネクター ３１ 洗浄液注入ライン接続部 ３２ 内針ハブ固定部 ４ 洗浄液流通路 ５ 卵吸引ライン ５１ 卵採取容器 ６ 洗浄液注入ライン ６１ 流量制御手段 ６２ フィルター ６３ クランプ ６４ ポンプ手段 ６４１ バルーン ６４２ シェル ７ 三方コック ８ 接続チューブ ９ 予備吸引ライン Ｎ 採卵針 DESCRIPTION OF SYMBOLS 1 Outer needle 11 Hub 12 Throttle part 13 Caulking member 14 Lumen 2 Inner needle 21 Hub 22 Cutting edge 23 Groove 24 Lumen 3 Branch connector 31 Cleaning liquid injection line connection part 32 Inner needle hub fixing part 4 Cleaning liquid flow path 5 Egg suction line 51 Egg collection container 6 Cleaning liquid injection line 61 Flow rate control means 62 Filter 63 Clamp 64 Pump means 641 Balloon 642 Shell 7 Three-way cock 8 Connection tube 9 Pre-suction line N Egg collection needle
Claims (5)
の先端部を所定長突出させて挿着された、先端に刃先が
設けられた中空の剛性を有する内針と、前記外針および
内針の基端部をそれぞれ固定する手段を備えた分岐コネ
クター、とを含み、前記外針の先端部に前記内針の先端
部と密着する絞り部が形成されるとともに、該絞り部に
対応する前記内針の外表面に洗浄液流通用の長手方向の
溝が設けられてなる採卵針。1. A hollow rigid outer needle having a cutting edge provided at a tip thereof, wherein the hollow outer needle is made of a synthetic resin, and a tip is provided at the tip of the hollow outer needle. A branch connector having means for fixing the proximal ends of the outer needle and the inner needle, respectively, and a throttle portion that is in close contact with the distal end of the inner needle is formed at the distal end of the outer needle; An egg collection needle in which a longitudinal groove for circulating a washing liquid is provided on an outer surface of the inner needle corresponding to the portion.
項１に記載の採卵針。2. The egg collection needle according to claim 1, wherein the outer needle is formed of a water absorbent resin.
憶樹脂で形成されてなる請求項１に記載の採卵針。3. The egg collection needle according to claim 1, wherein the outer needle is formed of a shape memory resin that softens at a temperature near body temperature.
基端部分で、それぞれ内針の内腔および外針の内腔と液
体連通するように接続された、卵採取容器を備えた卵吸
引ラインおよび、バルーンと該バルーンを密封するシェ
ルからなるポンプ手段を備えた洗浄液注入ラインを含
み、該卵吸引ラインと洗浄液注入ラインが流路切替手段
を介して接続されてなる洗浄吸引採卵装置。4. The egg collection needle according to claim 1, and an egg collection container connected at the proximal end of the egg collection needle to be in fluid communication with the lumen of the inner needle and the lumen of the outer needle, respectively. Cleaning suction including an egg suction line provided with a pump and a pump means comprising a balloon and a shell for sealing the balloon, wherein the egg suction line and the cleaning liquid injection line are connected via flow path switching means Egg collecting equipment.
てなる請求項４に記載の洗浄吸引採卵装置。5. The washing suction egg collecting apparatus according to claim 4, wherein a preliminary suction line is connected to the flow path switching means.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000001278A JP2001190560A (en) | 2000-01-07 | 2000-01-07 | Ovum collection needle and washing and absorbing ovum collection device using the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000001278A JP2001190560A (en) | 2000-01-07 | 2000-01-07 | Ovum collection needle and washing and absorbing ovum collection device using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2001190560A true JP2001190560A (en) | 2001-07-17 |
Family
ID=18530524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000001278A Pending JP2001190560A (en) | 2000-01-07 | 2000-01-07 | Ovum collection needle and washing and absorbing ovum collection device using the same |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2001190560A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2394179A (en) * | 2001-10-25 | 2004-04-21 | Smiths Group Plc | Dual lumen oocyte recovery needle |
| WO2004100807A1 (en) * | 2003-05-19 | 2004-11-25 | Jiahui Xia | A micro-holding pipette with an oblique opening |
| WO2008120824A1 (en) | 2007-03-30 | 2008-10-09 | Nipro Corporation | Metal needle usable in echo imaging |
| JP2010534332A (en) * | 2007-09-28 | 2010-11-04 | ヴィトロライフ スウェーデン アクチボラゲット | Sampling needle |
| WO2014115304A1 (en) * | 2013-01-25 | 2014-07-31 | 株式会社北里メディカル | Needle for collecting living cell |
| CN117084764A (en) * | 2022-05-12 | 2023-11-21 | 浙江明悦医疗科技有限公司 | Puncture needle, double chamber egg retrieval needle and egg cell collection system |
-
2000
- 2000-01-07 JP JP2000001278A patent/JP2001190560A/en active Pending
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2394179A (en) * | 2001-10-25 | 2004-04-21 | Smiths Group Plc | Dual lumen oocyte recovery needle |
| GB2394179B (en) * | 2001-10-25 | 2004-11-10 | Smiths Group Plc | Medico-surgical instruments |
| US6979339B2 (en) | 2001-10-25 | 2005-12-27 | Smiths Group Plc | Medico-surgical instruments |
| WO2004100807A1 (en) * | 2003-05-19 | 2004-11-25 | Jiahui Xia | A micro-holding pipette with an oblique opening |
| US8287464B2 (en) | 2007-03-30 | 2012-10-16 | Nipro Corporation | Metal needle usable in echo imaging |
| WO2008120824A1 (en) | 2007-03-30 | 2008-10-09 | Nipro Corporation | Metal needle usable in echo imaging |
| JP2010534332A (en) * | 2007-09-28 | 2010-11-04 | ヴィトロライフ スウェーデン アクチボラゲット | Sampling needle |
| US9907571B2 (en) | 2007-09-28 | 2018-03-06 | Vitrolife Sweden Ab | Sampling needle |
| US10765454B2 (en) | 2007-09-28 | 2020-09-08 | Vitrolife Sweden Ab | Sampling needle |
| WO2014115304A1 (en) * | 2013-01-25 | 2014-07-31 | 株式会社北里メディカル | Needle for collecting living cell |
| JP6050837B2 (en) * | 2013-01-25 | 2016-12-21 | 株式会社北里メディカル | Biological cell collection needle |
| US10194940B2 (en) | 2013-01-25 | 2019-02-05 | Kitazato Corporation | Living cell collection needle |
| CN117084764A (en) * | 2022-05-12 | 2023-11-21 | 浙江明悦医疗科技有限公司 | Puncture needle, double chamber egg retrieval needle and egg cell collection system |
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