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JP2005229974A - Health food - Google Patents

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JP2005229974A
JP2005229974A JP2004075309A JP2004075309A JP2005229974A JP 2005229974 A JP2005229974 A JP 2005229974A JP 2004075309 A JP2004075309 A JP 2004075309A JP 2004075309 A JP2004075309 A JP 2004075309A JP 2005229974 A JP2005229974 A JP 2005229974A
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tea
fermented
guarana
noodles
extract
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Japanese (ja)
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Yumiko Yamazaki
弓子 山崎
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Abstract

<P>PROBLEM TO BE SOLVED: To provide a means for taking catechin and epicatechin of guarana as bean curd, teas (green tea, oolong tea, etc.), yoghurt, cheese, black tea (fermented tea), lactic acid beverage, soy sauce, soybean paste, alcoholic beverages (Japanese sake, white liquor, beer, wine, etc.), fermented soybean, pickles, noodles (buckwheat noodles, wheat noodles, etc.), confectioneries (cookies, cakes, puddings, coffee jelly, Ogura type sweet jelly made from bean jam, caramel and vanilla ice cream), soup (egg soup), a seasoning, etc., not as a medicine while enjoying their tastes naturally in daily life. <P>SOLUTION: This health food for preventing Alzheimer type dementia of mainly with elderly persons, not as the medicine is constituted by fermenting the daily taken bean curd, teas (green tea, oolong tea, etc.), fermented foods (yoghurt, lactic acid beverage, black tea, cheese, alcoholic beverages, soybean paste, soy sauce, fermented soybean and pickles) with guarana powder and its extract liquid. Thereby, while enjoying the tastes naturally in the daily life, it is possible to take catechin and epicatechin of the guarana. <P>COPYRIGHT: (C)2005,JPO&NCIPI

Description

この発明は、主に、老人のアルツハイマー型痴呆症予防、ベーターアミロイドタンパク分解態を有するカテキン、エピカテキンを含有するガラナパウダー、もしくはその抽出液を混合した豆腐とお茶(緑茶、ウーロン茶等)からなる健康食品。ヨーグルト、チーズ、紅茶(発酵茶)、乳酸飲料、醤油、味噌、酒類(日本酒、焼酎、ビール、ワイン等)、納豆、漬物等の発酵食品の原料に混合し、同時に発酵処理を行った発酵健康食品。又は、ガラナパウダーもしくはその抽出物を発酵させ麺類(そば、うどん等)、菓子類(クッキー、ケーキ、プリン、コーヒーゼリー、小倉羊羹、キャラメル、バニラアイスクリーム)、豆腐、お茶(緑茶、ウーロン茶等)、スープ、調味料等の食品に混入させてなる健康食品等に関するものである。The present invention mainly consists of tofu and tea (green tea, oolong tea, etc.) mixed with catechin having a beta-amyloid proteolytic state, catechin having epicatechin, galana powder, or an extract thereof. healthy food. Yogurt, cheese, black tea (fermented tea), lactic acid beverage, soy sauce, miso, liquor (Japanese sake, shochu, beer, wine, etc.), fermented foods such as natto, pickles, etc. Food. Or fermented guarana powder or its extract, noodles (buckwheat noodles, etc.), confectionery (cookies, cakes, pudding, coffee jelly, okura gourd, caramel, vanilla ice cream), tofu, tea (green tea, oolong tea, etc.) It relates to health foods mixed in foods such as soups and seasonings.

ガラナパウダーもしくはその抽出液を混合する豆腐、お茶(緑茶、ウーロン茶等)、混合発酵するヨーグルト、チーズ、紅茶(発酵茶)、乳酸飲料、醤油、みそ、酒類(日本酒、焼酎、ビール、ワイン等)、納豆、漬物、又、そのものを発酵し混合した麺類(そば、うどん等)、菓子類(クッキー、ケーキ、プリン、コーヒーゼリー、小倉羊羹、キャラメル、バニラアイスクリーム等)、スープ、お茶(緑茶、ウーロン茶等)、調味料等に老人のアルツハイマー型痴呆症予防食品としてカテキン、エピカテキンを利用した例はない。ガラナの成分であるカテキンには、アルツハイマー病の原因とされる物質であるベーターアミロイドによる神経細胞の死滅を防ぐ効果があることを鈴鹿医療科学大学大学院の鈴木郁功教授らの研究グループが突き止めた。ネズミからとった神経細胞を培養し、一方にはベーターたんぱくとカテキンを与え観察した。その結果、ベーターたんぱくだけで処理した細胞は約4割が死滅し、カテキンも加えた細胞はほとんど死ななかった。又、カテキンの効能についての他の学説は以下のとおりである。脳虚血疾患やアルツハイマー病で起こる神経変性は、ミトコンドリアの機能低下やカスパーゼの活性化を経由した神経細胞のアポトーシスによる。アポトーシスを誘導するこれらの現象前に、prostateapotosis rsponse−4(Par−4)という蛋白質が誘導された。また、β−アミロイドペプチドの添加によっても誘導された。Par−4は栄養因子の除去によるアポトーシスにおいても誘導されるが、このアポトーシスは抗酸化物質によって抑制された。茶及びガラナのカテキンはβ−アミロイドペプチド毒性を抑制した。β−アミロイドペプチドは活性酸素を産生させたが、カテキンは活性酸素産生を完全に抑制した。β−アミロイドペプチドのうち、あるフラグメント(Aβ25−35)が海馬神経細胞に毒性を示した。この毒性の抑制物質を検索した結果、生薬ガラナ抽出物のカテキンが強く抑制した。カテキンと以前からβ−アミロイドペプチド毒性抑制物質とされているビタミンEの抑制機構を検討した。その結果、両者はβ−アミロイドによる酸素ラジカル産生過程のいずれかを抑制していた。 ガラナは、全体的な老化の進行の防止にも著しい効果を発揮する。心臓の活動を活発化させ、老化した器官に起こりやすいうっ血を防止する。
2002.03.22日本経済新聞 鈴木郁功(鈴鹿医療科学大学大学院) GO527A化学と生物 VOL.38,NO.4,PAGE.212−214 2000 新家一男、他2名(東大) G0089A バイオサイエンスとインダストリーVOL.54,NO.12,PAGE.861−862 1996 O guarana,Agric.E Pec.,Rio de Janeiro,2(42),619−621(1930).
Tofu, tea (green tea, oolong tea, etc.) mixed with guarana powder or its extract, mixed fermentation yogurt, cheese, tea (fermented tea), lactic acid beverage, soy sauce, miso, liquor (sake, shochu, beer, wine, etc.) Natto, pickles, fermented and mixed noodles (buckwheat noodles, etc.), confectionery (cookies, cakes, pudding, coffee jelly, Ogura gourd, caramel, vanilla ice cream, etc.), soup, tea (green tea, There is no example of using catechin or epicatechin as a food for preventing Alzheimer's dementia in the elderly for oolong tea and seasonings. The research group of Professor Satoshi Suzuki and other professors at the Graduate School of Suzuka University of Health Sciences found that catechin, a component of guarana, has the effect of preventing neuronal cell death caused by beta-amyloid, a substance that causes Alzheimer's disease. . Neurons taken from mice were cultured, and one was given beta protein and catechin and observed. As a result, about 40% of the cells treated with only beta protein were killed, and cells to which catechin was added hardly died. Other theories about the effects of catechins are as follows. Neurodegeneration that occurs in cerebral ischemic disease and Alzheimer's disease is due to neuronal apoptosis through mitochondrial hypofunction and caspase activation. Prior to these phenomena inducing apoptosis, a protein called prosteapotosis rsponse-4 (Par-4) was induced. It was also induced by the addition of β-amyloid peptide. Par-4 is also induced in apoptosis by removal of trophic factors, but this apoptosis was suppressed by antioxidants. Tea and guarana catechins suppressed β-amyloid peptide toxicity. β-amyloid peptide produced active oxygen, whereas catechin completely suppressed active oxygen production. Among β-amyloid peptides, a fragment (Aβ25-35) was toxic to hippocampal neurons. As a result of searching for the inhibitory substance of this toxicity, the catechin of the crude drug guarana extract was strongly suppressed. The inhibitory mechanism of catechin and vitamin E, which has been regarded as a β-amyloid peptide toxicity inhibitor, has been studied. As a result, both suppressed one of the oxygen radical production processes by β-amyloid. Guarana also has a significant effect on preventing the overall progression of aging. Increases heart activity and prevents congestion that tends to occur in aging organs.
2002.3.22 Nihon Keizai Shimbun Yasuyoshi Suzuki (Graduate School, Suzuka University of Medical Science) GO527A Chemistry and Biology VOL. 38, NO. 4, PAGE. 212-214 2000 Kazuo Shinke and 2 others (The University of Tokyo) G0089A Bioscience and Industry VOL. 54, NO. 12, PAGE. 861-862 1996 O guarana, Agric. E Pec. , Rio de Janeiro, 2 (42), 619-621 (1930).

本製品は、主に老人のアルツハイマー型痴呆症予防に対して薬ではなく、日常摂取する豆腐、お茶(緑茶、ウーロン茶等)、酒類(日本酒、焼酎、ビール、ワイン等)、ヨーグルト、チーズ、紅茶(発酵茶)、乳酸飲料、醤油、味噌、納豆、漬物等、麺類(そば、うどん等)、菓子類(クッキー、ケーキ、プリン、コーヒーゼリー、小倉羊羹、キャラメル、バニラアイスクリーム等)、スープ(たまごスープ等)、調味料等の形で供給することを目的とする。This product is not mainly a drug for the prevention of Alzheimer-type dementia in elderly people, but tofu, tea (green tea, oolong tea, etc.), alcoholic beverages (sake, shochu, beer, wine, etc.), yogurt, cheese, black tea (Fermented tea), lactic acid beverage, soy sauce, miso, natto, pickles, noodles (soba, udon, etc.), confectionery (cookies, cakes, pudding, coffee jelly, Ogura goat, caramel, vanilla ice cream, etc.), soup ( It is intended to be supplied in the form of egg soup and seasonings.

老人のアルツハイマー型痴呆症予防に対して、薬ではなく、豆腐、お茶(緑茶、ウーロン茶等)として摂取するものとする。ガラナの房を自然発酵させ、種子をすりつぶす粉末、或いは種子をすりつぶしたものを浸漬して得る抽出液を豆腐、お茶(緑茶、ウーロン茶)に混合、又はヨーグルト、チーズ、紅茶(発酵茶)、乳酸飲料、醤油、みそ、酒類(日本酒、焼酎、ビール、ワイン等)、納豆、漬物等の発酵食品の原料に混合し発酵、又はガラナパウダーもしくはその抽出液を発酵させ、豆腐、お茶(緑茶、ウーロン茶等)、麺類 (そば、うどん等)、菓子類(クッキー、ケーキ、プリン、コーヒーゼリー、小倉羊羹、キャラメル、バニラアイスクリーム等)、スープ(たまごスープ)、調味料等の食品に混合した健康食品。For the prevention of Alzheimer-type dementia in the elderly, it should be taken as tofu and tea (green tea, oolong tea, etc.) instead of medicine. Extracts obtained by fermenting a bunch of guarana and then pulverizing the seeds or mashing the seeds are mixed with tofu, tea (green tea, oolong tea), or yogurt, cheese, black tea (fermented tea), lactic acid Beverages, soy sauce, miso, liquor (Japanese sake, shochu, beer, wine, etc.), fermented food ingredients such as natto, pickles, etc., fermented guarana powder or its extract, tofu, tea (green tea, oolong tea) Etc.), noodles (buckwheat noodles, etc.), confectionery (cookies, cakes, pudding, coffee jelly, okura gourd, caramel, vanilla ice cream, etc.), soup (egg soup), and health foods mixed with seasonings .

本発明により、薬ではなく、豆腐、お茶(緑茶、ウーロン茶等)及びヨーグルト、チーズ、紅茶(発酵茶)、乳酸飲料、醤油、味噌、酒類(日本酒、焼酎、ビール、ワイン等)、納豆、漬物、麺類(そば、うどん等)、菓子類(クッキー、ケーキ、プリン、コーヒーゼリー、小倉羊羹、キャラメル、バニラアイスクリーム)、スープ(たまごスープ)、調味料等として自然に日常生活の中で味覚を楽しみながら、ガラナのカテキン、エピカテキンを摂取することができる。According to the present invention, instead of medicine, tofu, tea (green tea, oolong tea, etc.) and yogurt, cheese, black tea (fermented tea), lactic acid beverage, soy sauce, miso, liquor (sake, shochu, beer, wine, etc.), natto, pickles , Noodles (buckwheat noodles, etc.), confectionery (cookies, cakes, pudding, coffee jelly, okura gourd, caramel, vanilla ice cream), soups (egg soup), seasonings, etc. You can ingest catechin and epicatechin of guarana while having fun.

ガラナパウダーもしくは、その抽出液を豆腐、お茶(緑茶、ウーロン茶等)、ヨーグルト、チーズ、紅茶(発酵茶)、乳酸飲料、醤油、味噌、酒類(日本酒、焼酎、ビール、ワイン等)、納豆、漬物、麺類(そば、うどん等)、菓子類(クッキー、ケーキ、プリン、コーヒーゼリー、小倉羊羹、キャラメル、バニラアイスクリーム等)、スープ、調味料等の原料と共に混合し、味付けをする。
焙煎したガラナ100gに対する分析結果
カフェイン 5.388%
黄色固定油 2.950%
赤色樹脂 7.800%
赤着色成分 1.520%
不結晶成分 0.050%
サポニン 0.060%
食物繊維 49.125%
澱粉 9.350%
水分 7.650%
ペクチン、林檎酸、粘液、塩分etc. 7.470%
ガラナ・タンニン酸 5.750%
ガラナの抽出液は粉末に対して、約40分の1に薄めたものとする。
ガラナパウダーもしくはその抽出液を混合又は、発酵させ混合するもの
(豆腐)
大豆 2カップ(400cc)、水 1200cc、にがり 小匙2杯
(緑茶、ウーロン茶)
生の茶葉 (1kg)
発酵食品の原料にガラナパウダーもしくはその抽出液を混合し発酵させるもの
(チーズ)
牛乳 5リットル 乳酸菌 50ml レンネット 0.5g
(ヨーグルト、プレーンヨーグルト)
牛乳 5リットル 乳酸菌 50ml
(乳酸飲料)
牛乳 300ml 砂糖 500g クエン酸 2g 乳酸 7ml エッセンス 少々
(紅茶)
生の茶葉 (1kg)
(醤油)
全粒の小麦 1.5kg 大豆 1.5kg 醤油用種麹 10g 天然の塩 1kg 水 4 リットル
(味噌)
大豆 13.5kg 糀 15枚(原料米15kg) 食塩 6.5〜7kg 煮汁 20kg
(清酒、焼酎)
米 5.4リットル 水 7.2リットル こうじ 3.6リットル ごはん 360ml
(ビール)
破砕麦芽 100リットル 水 220リットル Be 12〜14度の麦芽汁 少々 ホップ 1.2〜1.5リットル
(ワイン)
ブドウ 2kg ブドウ酒酵母 2g
(ウイスキー)
大麦麦芽 100リットル 水 220リットル Be 12〜14度の麦芽汁 少々
(納豆)
大豆 500g 納豆菌 0.1g 塩 小匙4分の1 砂糖 小匙2分の1
(漬物)
糠 500g 塩 75g 水 500cc キュウリ 3〜4本
こんぶとうがらし(適宜)
ガラナパウダーもしくはその抽出液を混合又は、発酵させ混合するもの
(うどん)
強力粉 300g 塩 小匙2 水 160ml
(そば)
そば粉 1000g 水 500cc
(クッキー)
バター 120g 砂糖 100g とき卵 M1個 薄力粉 240g
(ケーキ)
薄力粉 90g 卵 M3個 砂糖 90g バター 15g 牛乳 大さじ1
(プリン)
牛乳 500ml 砂糖 70g バニラエッセンス 少々
(コーヒーゼリー)
水 100ml 粉ゼラチン 10g 水 2カップ インスタントコーヒー 大さじ 2 砂糖 50g
(小倉羊羹)
糸寒天 5g 水 200ml グラニュー糖 480g ゆで小豆300g
(キャラメル)
コンデンスミルク 200g 砂糖 250g 水あめ 150g バター 110g サラダ油 少々
(バニラアイスクリーム)
生クリーム 200cc 牛乳 100cc 卵 2個 砂糖 大さじ3杯 バニラエッセンス 5〜6滴
(たまごスープ)
ベーコン 2枚 玉葱 1個 人参 2分の1本 パセリ 1えだ たまご 2個 ブイヨン 1個 塩 小さじ1 こしょう 少々 醤油 大さじ1 水 800cc
(かつおだし)
削り節(花鰹)ひとつかみ 約20g 水 5カップ
上記の原材料に対し100ppmのガラナパウダーもしくはガラナの抽出液(エキス)を加え、混合又は発酵する。又、ガラナパウダー又はガラナ抽出液10gを酵母エキス3g、麦芽エキス3g、ブドウ糖10g、ペプトン5g、蒸留水1000mlと共にBacillus属又は、酵母菌により発酵処理する。これを凍結乾燥し豆腐、お茶(緑茶、ウーロン茶等)、麺類(そば、うどん等)、菓子類(クッキー、ケーキ、プリン、コーヒーゼリー、小倉羊羹、キャラメル、バニラアイスクリーム等)、スープ(たまごスープ)、調味料等の食品に対し、100ppm〜50ppm混合する健康食品。
Guarana powder or its extract is tofu, tea (green tea, oolong tea, etc.), yogurt, cheese, black tea (fermented tea), lactic acid beverage, soy sauce, miso, liquor (sake, shochu, beer, wine, etc.), natto, pickles Mix with raw materials such as noodles (soba, udon, etc.), confectionery (cookies, cakes, pudding, coffee jelly, okura gourd, caramel, vanilla ice cream, etc.), soup, seasonings, etc.
Analysis result for 100g of roasted guarana Caffeine 5.388%
Yellow fixed oil 2.950%
Red resin 7.800%
Red coloring component 1.520%
Amorphous component 0.050%
Saponin 0.060%
Dietary fiber 49.125%
Starch 9.350%
Moisture 7.650%
Pectin, apple acid, mucus, salinity etc. 7.470%
Guarana tannic acid 5.750%
It is assumed that the extract of guarana is diluted to about 1/40 of the powder.
Mixing or fermenting guarana powder or its extract (tofu)
2 cups of soybean (400 cc), 1200 cc of water, 2 cups of bittern (green tea, oolong tea)
Raw tea leaves (1kg)
Fermented food ingredients mixed with guarana powder or its extract and fermented (cheese)
Milk 5 liters Lactic acid bacteria 50ml Rennet 0.5g
(Yogurt, plain yogurt)
Milk 5 liters Lactic acid bacteria 50 ml
(Lactic acid beverage)
Milk 300ml Sugar 500g Citric acid 2g Lactic acid 7ml Essence a little (tea)
Raw tea leaves (1kg)
(Soy sauce)
Whole wheat 1.5kg Soybean 1.5kg Soy sauce seed candy 10g Natural salt 1kg Water 4 liters (Miso)
Soybean 13.5kg 糀 15 pieces (raw rice 15kg) Salt 6.5-7kg Boiled juice 20kg
(Sake, shochu)
Rice 5.4 liters water 7.2 liters koji 3.6 liters rice 360 ml
(Beer)
Crushed malt 100 liters Water 220 liters Be 12 to 14 degree malt juice A little hop 1.2 to 1.5 liters (wine)
Grape 2kg Wine yeast 2g
(whisky)
Barley malt 100 liters water 220 liters Be 12-14 degrees malt juice a little (natto)
Soybean 500g Natto 0.1g Salt A quarter of sugar A half of sugar
(pickles)
500 500g Salt 75g Water 500cc Cucumber 3-4 cucumbers (as appropriate)
Mixed or fermented with guarana powder or its extract (Udon)
Powerful powder 300g Salt Komari 2 Water 160ml
(Soba)
Buckwheat flour 1000g Water 500cc
(cookie)
Butter 120g Sugar 100g Toki egg M1 Soft flour 240g
(cake)
Soft flour 90g Egg M3 Sugar 90g Butter 15g Milk 1 tablespoon milk
(Pudding)
Milk 500ml Sugar 70g Vanilla extract a little (coffee jelly)
Water 100ml Powdered gelatin 10g Water 2 cups Instant coffee 2 tablespoons Sugar 50g
(Ogura Yokan)
Thread agar 5g Water 200ml Granulated sugar 480g Boiled red beans 300g
(caramel)
Condensed milk 200g Sugar 250g Mizuame 150g Butter 110g Salad oil A little (vanilla ice cream)
Fresh cream 200cc Milk 100cc 2 eggs 3 tablespoons sugar 5-6 drops vanilla extract (egg soup)
2 bacon 1 onion 1 carrot 1/2 parsley 1 edama 2 bouillon 1 1 teaspoon salt a little 1 tablespoon soy sauce 800 cc water
(dashi of Katsuo)
One bite of a shaving node (flower bud) About 20 g Water 5 cups 100 ppm guarana powder or guarana extract (extract) is added to the above ingredients and mixed or fermented. Moreover, 10 g of guarana powder or guarana extract is fermented with 3 g of yeast extract, 3 g of malt extract, 10 g of glucose, 5 g of peptone and 1000 ml of distilled water with Bacillus genus or yeast. Freeze-dried tofu, tea (green tea, oolong tea, etc.), noodles (soba, udon, etc.), confectionery (cookies, cakes, pudding, coffee jelly, Ogura gourd, caramel, vanilla ice cream, etc.), soup (egg soup) ), Health foods that are mixed with 100 ppm to 50 ppm of food such as seasonings.

Claims (3)

ガラナパウダーもしくは、その抽出物を豆腐とお茶(緑茶、ウーロン茶等)に混入させる健康食品。Health food in which guarana powder or its extract is mixed with tofu and tea (green tea, oolong tea, etc.). ガラナパウダーもしくはその抽出物をヨーグルト、チーズ、紅茶(発酵茶)、乳酸飲料、醤油、味噌、酒類(日本酒、焼酎、ビール、ワイン等)、納豆、漬物等の発酵食品の原料に混合し、同時に発酵処理を行った発酵健康食品。Mix guarana powder or its extract with fermented food ingredients such as yogurt, cheese, black tea (fermented tea), lactic acid beverage, soy sauce, miso, liquor (sake, shochu, beer, wine, etc.), natto, pickles Fermented health food that has been fermented. ガラナパウダーもしくはその抽出物を発酵させ、麺類(そば、うどん等)、菓子類(クッキー、ケーキ、プリン、コーヒーゼリー、小倉羊羹、キャラメル、バニラアイスクリーム)、豆腐、お茶(緑茶、ウーロン茶等)、スープ(たまごスープ)、調味料等に混入させてなる健康食品。Fermented guarana powder or its extract, noodles (buckwheat noodles, etc.), confectionery (cookies, cakes, pudding, coffee jelly, Ogura gourd, caramel, vanilla ice cream), tofu, tea (green tea, oolong tea, etc.), Health food mixed with soup (egg soup) and seasonings.
JP2004075309A 2004-02-17 2004-02-17 Health food Pending JP2005229974A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2127529A4 (en) * 2007-01-24 2010-02-24 Kao Corp Cakes
US7989009B2 (en) 2006-02-02 2011-08-02 Advocare International, L.P. Composition and method for promoting weight loss
KR20190107868A (en) * 2018-03-13 2019-09-23 해남에다녀왔습니다 영농조합법인 Method for Manufacturing Soybean Curd Ripened within Fermented Soybean Paste

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7989009B2 (en) 2006-02-02 2011-08-02 Advocare International, L.P. Composition and method for promoting weight loss
EP2127529A4 (en) * 2007-01-24 2010-02-24 Kao Corp Cakes
KR20190107868A (en) * 2018-03-13 2019-09-23 해남에다녀왔습니다 영농조합법인 Method for Manufacturing Soybean Curd Ripened within Fermented Soybean Paste
KR102081208B1 (en) * 2018-03-13 2020-02-25 해남에다녀왔습니다 영농조합법인 Method for Manufacturing Soybean Curd Ripened within Fermented Soybean Paste

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