JP2008088104A - W/o/w emulsion and external preparation and cosmetic - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a W/O/W emulsion having good stability with time over a long period of time even when an electrolyte at a high concentration is formulated in its inner aqueous phase. <P>SOLUTION: The W/O/W emulsion, and an external preparation and a cosmetic comprising the emulsion have good stability with time over the long period of time even when the electrolyte with high concentration is formulated in the inner aqueous phase. The W/O/W emulsion is obtained by emulsifying and dispersing W/O emulsion in an aqueous phase prepared by formulating (A) alkylated polysaccharides having a 6-22C straight chain or a 6-22C branched alkyl group which may contain an unsaturated bond with (B) a phospholipid and (C) an ionic surfactant. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to a W / O / W emulsion, an external preparation, and a cosmetic. More specifically, even if a high concentration electrolyte is blended in the inner aqueous phase of the W / O / W emulsion, the stability over time is long. The present invention relates to a W / O / W emulsion, an external preparation and a cosmetic, which are characterized by being good.

  The W / O / W type emulsion is an emulsion in which oil (O) droplet particles in which water (W) droplet particles are confined are dispersed in an outer aqueous phase (W). Various active ingredients can be blended in the internal water phase and oil phase, or two water-soluble active ingredients can be blended without contacting each other, so it has been actively studied in the fields of food, pharmaceuticals, cosmetics, etc. ing. In the cosmetics field, sustained release of active ingredients, stable blending of water-soluble substances, compatibility between the moisture retention of W / O emulsions and the feeling of use of O / W emulsions, and a fresh feeling of use that causes phase inversion during application. May be used for the purpose.

  However, the W / O / W emulsion tends to cause coalescence of the inner aqueous phase and the outer water phase, aggregation / merging of the W / O emulsion, and coalescence / enlargement of the inner aqueous phases. Therefore, since it is difficult to maintain the form for a long period of time, improvement of stability over time is a big problem.

  Various studies have been made on such problems. For example, a method of blending a polysaccharide as a water-soluble thickener in an outer aqueous phase (Patent Document 1), a method of dispersing a W / O emulsion in an outer aqueous phase using an alkyl-modified carboxyvinyl polymer (Patent Document 2) 3), a method of adding an osmotic pressure regulator when dispersing vesicles having an aqueous phase in an aqueous dispersion medium (Patent Document 4), a W / O emulsion using a specific bentonite or metal soap And then preparing a W / O / W using an N-long-chain acyl acidic amino acid mono salt or an aqueous nonionic surfactant (Patent Documents 5 and 6), a stable W / O emulsion interface In order to reinforce the membrane, a method using a glycerin condensed ricinoleic acid ester or a saccharide ester of ricinoleic acid self-condensate as a surfactant (Patent Documents 7 and 8) is disclosed. However, when a high concentration electrolyte is blended in the inner aqueous phase of the W / O / W type emulsion, the temporal stability of the W / O / W type emulsion over a long period of time is not always sufficient.

  On the other hand, the present inventors have obtained an O / W emulsion having both a depolyoxyethylene-based emulsification function and a thickening performance, which is "safe for the living body and excellent in environmental compatibility", and has excellent stability over time. (A) an alkylated polysaccharide having a linear and / or branched alkyl group having 6 to 22 carbon atoms that may contain an unsaturated bond, (B) a phospholipid, (C) An ionic surfactant and an O / W emulsifier composition containing the same were proposed (Patent Document 9). As the present inventors are advancing application research of this O / W emulsifier composition, it is possible to obtain an O / W emulsion having extremely good long-term stability even when a high concentration of electrolyte is blended. By using this O / W emulsifier composition as the outer aqueous phase of the W / O / W emulsion, it is stable over time even if a high concentration of electrolyte is added to the inner aqueous phase and / or the outer aqueous phase. It was found that a W / O / W type emulsion having good properties can be obtained.

Although W / O / W type animal vaccines that use high molecular weight polysaccharides and fatty acid esters but do not use phospholipids have been disclosed, a high concentration electrolyte is included. No mention is made of the stability over time in this case (Patent Documents 10 and 11).
JP 58-183611 A JP-A-11-33391 JP 2002-275029 A JP 2002-187834 A JP 59-127646 A JP-A-60-193529 JP 59-56324 A JP 2000-292269 A JP2005-179241 JP 2001-39891 A JP 2003-128578 A

  To provide a W / O / W emulsion, an external preparation and a cosmetic which have good stability over time even when a high concentration electrolyte is added to the inner aqueous phase.

  As a result of intensive studies to solve these problems, the present inventors have found that (A) an alkylated polysaccharide having a straight chain and / or branched alkyl group having 6 to 22 carbon atoms which may contain an unsaturated bond. When a high concentration electrolyte is added to the inner aqueous phase by emulsifying and dispersing the W / O emulsion in the aqueous phase containing (B) phospholipid and (C) ionic surfactant. However, the present inventors have found that this W / O / W type emulsion, an external preparation and a cosmetic which have good stability over time for a long period of time can be obtained, and the present invention has been completed.

  A long-term stability test of a W / O / W emulsion obtained by emulsifying and dispersing various W / O emulsions containing a high concentration of electrolyte in an aqueous phase containing (A) to (C) as essential components. When implemented, the effect was remarkable in any case. Although the detailed mechanism of action regarding the combination of the components (A) to (C) is not clear, various W / O emulsions are emulsified and / or in the aqueous phase containing (A) to (C) as essential components. The dispersed W / O / W type emulsion makes it possible to stably blend a high concentration of electrolyte in the inner aqueous phase over a long period of time.

  As the alkylated polysaccharide of component (A) used in the present invention, an alkylated polysaccharide obtained from cellulose, seaweed, seed, sap, fruit, or microbial product can be used.

  Specifically, polysaccharides such as alginic acid, carrageenan, agar, fercelan, guar gum, quinseed, konjac mannan, tamarind gum, tara gum, dextrin, starch, gum arabic, locust bean gum, karaya gum, gati gum, tragacanth gum, xanthan gum, pectin, cellulose The alkylated product can be used.

  Furthermore, the modified product of the polysaccharide can be used after alkylation. Specific examples include alkylated products of water-soluble cellulose ethers such as methylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, hydroxyethylmethylcellulose, and hydroxypropylmethylcellulose.

  The alkylated polysaccharide of component (A) used in the present invention is particularly preferably an alkyl glyceryl etherified product of the polysaccharide and / or a modified product thereof. Alkyl glyceryl etherification is a particularly preferable method for producing the alkylated polysaccharide of the present invention because the production method is simple and there are few by-products.

  As the component (A) of the present invention, a cellulose ether having an alkyl group having 1 to 3 carbon atoms and / or a hydroxyalkyl group having 2 to 4 carbon atoms may have an unsaturated bond and has 6 to 22 carbon atoms. A linear and / or branched alkyl glyceryl ether is particularly preferable because it exhibits very good emulsifying power and thickening action.

  Methods for producing these alkyl glyceryl etherified celluloses are known and disclosed, for example, in JP-A-3-12401. That is, in the presence of an alkaline agent such as caustic soda, an alkyl glycidyl ether as an alkylating agent is added to the water-soluble cellulose ether described above, and mixed and reacted at 50 to 80 ° C. for several hours, and then the alkaline agent is neutralized. It can be obtained by washing and drying as necessary.

  As alkyl glycidyl ether here, what has a C6-C22 alkyl group which may be unsaturated or a branched structure can be used conveniently. Specific examples include behenyl glycidyl ether, stearyl glycidyl ether, isostearyl glycidyl ether, oleyl glycidyl ether, cetyl glycidyl ether, decyl glycidyl ether, 2-ethylhexyl glycidyl ether, and hexyl glycidyl ether.

  The alkylation rate of the alkylated polysaccharide of the present invention is 0.001-1 mol, preferably 0.001-0.5 mol, more preferably 0.001-0.1 mol per constituent glucose unit.

  As the phospholipid of the component (B) used in the present invention, lecithin such as soybean lecithin, egg yolk lecithin, hydrogenated soybean lecithin, hydrogenated egg yolk lecithin, lysolecithin obtained by converting these lecithins into a monoacyl form by enzyme treatment and / or Examples include hydrogenated lysolecithin and hydroxylated hydroxylecithin. These may be crude lecithin containing egg yolk oil or vegetable oil as a raw material, or purified lecithin that has been deoiled and decolorized and purified.

  Furthermore, phospholipid fractions in lecithin such as phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine, phosphatidylserine, phosphatidic acid and the like can be used individually or in combination.

  In the present invention, hydrogenated soybean lecithin is particularly preferable in terms of emulsifying power and oxidation stability.

As the ionic surfactant of the component (C) used in the present invention, an anionic surfactant: fatty acid soap, α-acylsulfonic acid, alkylsulfonic acid, alkylallylsulfonic acid, alkylnaphthalenesulfonic acid, alkylsulfuric acid, POE alkyl ether sulfuric acid, alkyl amide sulfuric acid, alkyl phosphoric acid, POE alkyl phosphoric acid, alkyl amide phosphoric acid, alkyloyl alkyl taurine, N-acyl amino acid, POE alkyl ether carboxylic acid,
Alkylsulfosuccinic acid, alkylsulfoacetic acid, acyl isethionic acid, acylated hydrolyzed collagen peptide, perfluoroalkyl phosphate, saponin, glycyrrhizic acid, glycyrrhetinic acid, sterol sulfates, sterol phosphates and / or their ants , Alkaline earth metals, alkanolamines, alkylamines, ammonium salts and the like.

  Cationic surfactants: alkyl trimethyl ammonium chloride, stearyl trimethyl ammonium chloride, stearyl trimethyl ammonium bromide, cetostearyl trimethyl ammonium chloride, distearyl dimethyl ammonium chloride, stearyl dimethyl benzyl ammonium chloride, behenyl trimethyl ammonium bromide, benzalkonium chloride , Behenic acid amidopropyldimethylhydroxypropylammonium chloride, stearic acid diethylaminoethylamide, stearic acid dimethylaminopropylamide, lanolin derivative quaternary ammonium, and the like. Further, tertiary amines such as fatty acid amide dialkylamines and salts thereof are also included.

  Amphoteric surfactants: carboxybetaine type, amide betaine type, sulfobetaine type, hydroxysulfobetaine type, amide sulfobetaine type, phosphobetaine type, aminocarboxylate type, imidazoline derivative type and the like.

About the composition ratio of (A)-(C) component, it is as follows by mass ratio.
(A) / (C) = 99.9 / 0.1-90 / 10
(A) / (B) = 99.9 / 0.1-30 / 70
(A) + (C) / (B) = 99.9 / 0.1-30 / 70
Preferably,
(A) / (C) = 99.5 / 0.5 to 90/10
(A) / (B) = 99 / 1-30 / 70
(A) + (C) / (B) = 99 / 1-30 / 70
More preferably,
(A) / (C) = 99/1 to 93/7
(A) / (B) = 90 / 10-40 / 60
(A) + (C) / (B) = 90 / 10-40 / 60

  The W / O / W emulsion of the present invention and the W / O emulsion that can be blended at the time of preparation of external preparations and cosmetics vary depending on the use, dosage form, blending purpose, etc., and are not particularly limited. Generally, a lipophilic surfactant up to about HLB 12 as an emulsifier, such as polyglycinyl hexaglyceryl, diglyceryl monooleate, POE (2) cetyl ether, POE (1) POP (8) cetyl ether, mono A method using sorbitan isostearate, an amino acid gel emulsification method, a method using an alkyl glyceryl ether, a polyhydric alcohol, a gel formed with water, a method using an organically modified clay mineral, or the like can be used.

  As an emulsifier for W / O using an organically modified clay mineral, commercially available products include NIKKOL Nikomulus WO (an organically modified clay mineral, a silicone-based emulsifier, a W / O emulsifier made of cyclic silicone, manufactured by Nikko Chemicals) and NIKKOL Nikomulus WO -NS (organic modified clay mineral, W / O emulsifier made of polyglycerin fatty acid ester, manufactured by Nikko Chemicals) and the like. By using these, an extremely stable W / O type emulsion can be prepared even if a large amount of oil is blended without blending an oil gelling agent or wax component.

  The W / O / W emulsion of the present invention, the external preparation and the salt to be blended in the inner water phase and / or the outer water phase of cosmetics vary depending on the use, dosage form, blending purpose, etc., and are particularly limited. However, inorganic salts, water-soluble active ingredients, and the like can be used, and powders and the like from which inorganic ingredients are eluted can be blended stably.

  Specifically, inorganic salts contained in sodium chloride, potassium chloride, magnesium chloride, calcium chloride, sodium citrate, sea salt, seaweed extract, organic salts such as sodium pyrrolidonecarboxylate, amino acids, and stratum corneum Water-soluble substances (NMF components (consisting of amino acids, pyrrolidone carboxylic acid, organic acids, urea, inorganic salts, etc.)), vitamins such as magnesium ascorbate phosphate, disodium ascorbate sulfate C derivatives and the like can be used.

  Furthermore, the W / O / W emulsion of the present invention, the external preparation, and the internal aqueous phase of the cosmetics can be stably mixed with water-soluble active ingredients (other than salts) that are difficult to mix with the aqueous phase.

  Specifically, components that are easily colored such as ascorbic acid, arbutin, kojic acid, catechin and apple tannin can be used.

  The blending amount of the salt to be blended in the W / O / W emulsion of the present invention, the external preparation and the inner aqueous phase of the cosmetic varies depending on the use, dosage form, blending purpose, etc., and is not particularly limited. Generally, 0.01-10.0 mass% is preferable in the whole quantity, More preferably, it is 0.1-5.0 mass%.

  When preparing the mixture of the components (A) to (C), the components (A) to (C) are weighed into a stirrer equipped with a heater and a temperature controller at a time, and stirred and mixed at 50 to 130 ° C. It ’s fine. As the stirrer, a paddle stirrer, a homomixer, a Henschel mixer, a kneader, a roll mill or the like can be used. In that case, water-soluble solvents such as glycerin, propylene glycol, 1,3-butanediol, carbitols, and / or liquid paraffin, 2-ethylhexyl palmitate, cetyl 2-ethylhexanoate, tri-2-ethylhexanoic acid glyceride By using liquid oil such as olive oil, a paste-like composition can be obtained. Furthermore, a high oil spot such as a higher alcohol can be mixed to form a wax, and it can also be formed into a flake with a flaker or the like.

  When the (A) to (C) components are used to prepare the W / O / W emulsion, the external preparation and the cosmetic of the present invention, as a mixture of the components (A) to (C), W / O / W type emulsion, external preparation and cosmetics, 0.1 to 30.0% by mass, preferably 0.5 to 20.0% by mass, more preferably 1.0 to 15.0% by mass To do.

  When the components (A) to (C) are used to prepare the W / O / W emulsion of the present invention, the external preparation, and the cosmetic, ordinary emulsification devices such as a paddle mixer and a homomixer can be used. In the preparation method, the aqueous phase containing the components (A) to (C) was stirred at a temperature of 50 ° C. to 80 ° C. while stirring with a homomixer or the like, cooled to 30 ° C. to 35 ° C., and prepared in advance. And a method of adding the / O type emulsion while stirring with a paddle mixer or the like.

  In the W / O / W type emulsion, the external preparation, and the cosmetic of the present invention, an oily component, a higher alcohol, a fatty acid, an active component, a moisturizing component, an antibacterial component, a viscosity adjusting agent, a pigment, and the like can be used in combination.

   As the oil component, any oil component generally used in cosmetics can be suitably used. Specifically, hydrocarbons such as squalane, olive squalane and liquid paraffin, vegetable oils such as olive oil and jojoba oil, animal oils such as beef tallow, waxes such as beeswax, carnauba wax, lanolin and candelilla wax, tri-2-ethylhexane Examples thereof include esters such as acid glycerin ester, myristic acid isopropyl ester and 2-ethylhexanoic acid cetyl ester, and silicones such as dimethylpolysiloxane, phenylmethylpolysiloxane and cyclic methylpolysiloxane.

  Examples of the higher alcohol include isooctanol, octanol, lauryl alcohol, oleyl alcohol, stearyl alcohol, behenyl alcohol, isostearyl alcohol, cholesterol and the like.

  Examples of fatty acids include octanoic acid, isooctanoic acid, capric acid, lauric acid, myristic acid, palmitic acid, oleic acid, stearic acid, behenic acid, linoleic acid, and linolenic acid.

  Specific examples of the active ingredient include whitening ingredients such as vitamin C derivatives such as ascorbic acid tetraisopalmitate, ascorbate monopalmitate, ascorbate phosphate magnesium ascorbate glucoside, arbutin, and kojic acid. Further, vitamin E which is an antioxidant component and its derivatives or polyphenols such as catechin, carotenoids, and the like, and ε-aminocaproic acid, lysozyme chloride, guaiazulene, hydrocortisone, vitamin A, vitamin D, nicotine which are anti-inflammatory components Acid amides, calcium pantothenate, allantoin, γ-oryzanol and the like, and vitamin E, γ-linolenic acid and the like which are skin nutrients can be preferably used.

  Moisturizing ingredients include glycerin, polyglycerin, propylene glycol, dipropylene glycol, 1,3-butanediol, sorbitol, sorbitan, pentaerythritol, xylitol and other polyhydric alcohols, chitosan, hyaluronic acid and other polysaccharides, pyrrolidone carboxylic Examples include amino acids such as acids. Similarly, ceramides and sphingolipids can also be suitably used.

  Antibacterial and antiseptic components include ethanol, methyl paraben, propyl paraben, phenoxyethanol and the like.

  Examples of the viscosity adjusting agent and the appearance adjusting agent include water-soluble polymers such as xanthan gum, hydroxyethyl cellulose, and carboxyvinyl polymer, and pearl agents such as higher fatty acid ethylene glycol esters.

  A nonionic surfactant can be used in combination with the W / O / W emulsion, the external preparation, and the cosmetic of the present invention as long as the characteristics are not impaired. Preferred nonionic surfactants include propylene glycol fatty acid ester, glycerin fatty acid ester, polyglycerin fatty acid ester, sorbitan fatty acid ester, POE sorbitan fatty acid ester, POE sorbitol fatty acid ester, POE glycerin fatty acid ester, POE alkyl ether, POE fatty acid ester, POE hydrogenated castor oil, POE castor oil, POE / POP copolymer, POE / POP alkyl ether, polyether-modified silicone lauric acid alkanolamide, alkylamine oxide and the like.

  The present invention will be described more specifically with reference to the following examples, but the technical scope of the present invention is not limited thereto.

<Production of alkylated polysaccharides>
300 g of polysaccharide was charged into a stainless steel 5-liter reactor having a nitrogen introducing device, a temperature controller, a reflux condenser, a dropping funnel, and a paddle-shaped stirring device, and 2 L of isopropanol was added thereto. The mixture was stirred at room temperature for 1 hour under a nitrogen stream, and each of the following four polysaccharides was dispersed in isopropanol. A 48% sodium hydroxide solution (50 g) was added to the dispersion under the same conditions, and the mixture was further stirred for 30 minutes. Next, 10 g of stearyl glycidyl ether was added dropwise thereto, and the mixture was stirred for 6 hours under reflux. After completion of the reaction, the reaction mixture was cooled and the solid matter was removed by filtration. The extracted solid was washed with 2 liters of isopropanol three times, and further with purified water until the pH of the washing liquid became neutral with pH test paper and dried to obtain alkylated polysaccharides 1 to 4. In addition, the raw material polysaccharide used hydroxypropyl methylcellulose, methylcellulose, guar gum, and potato dextrin.
Alkylated polysaccharide 1: Stearyl glyceryl etherified hydroxypropyl methylcellulose alkylated polysaccharide 2: Stearyl glyceryl etherified methylcellulose alkylated polysaccharide 3: Stearyl glyceryl etherified guar gum Alkylated polysaccharide 4: Stearyl glyceryl etherified potato dextrin

<Production Example of Mixture of Components (A) to (C)>
A stainless steel 10-liter stirrer having a temperature controller, a nitrogen introducing device, and a paddle-shaped stirrer is charged with the total amount of the raw materials shown in Table 1 at 5 Kg, and filled with nitrogen at 70 to 80 ° C., 200 The mixture was stirred at a stirring speed of 2 times / minute for 2 hours. Further, the mixture is cooled while stirring at the same stirring speed, and when the temperature of the system reaches 40 ° C., the stirring is stopped and the mixture is taken out. 1 to 6 and comparative components 1 to 4 were obtained. The resulting mixture was a light brown paste. The numerical value in a table | surface represents the mass%.

<Preparation of W / O / W emulsion>
Table 3 shows the O / W emulsions shown in Table 2 and the mixtures 1 to 6 of the components (A) to (C) and the mixtures 1 to 4 of the comparative components that are essential components in the present invention product. W / O / W type emulsions of Invention products 1 to 6 and Comparative products 1 to 4 were prepared. The numerical value in a table | surface represents the mass%.

<Stability of W / O / W emulsion>
Immediately after preparation, the stability of the emulsion stored for 3 months at 45 ° C. (a constant temperature bath manufactured by Yamato Scientific Co., 45 ° C. ± 2 ° C.) was evaluated. The determination was made by observing the W / O / W type emulsion stored in a 100 ml transparent glass container under a microscope.

<Conductivity of W / O / W emulsion>
Immediately after the preparation, the electrical conductivity at 22 ° C. of the W / O / W emulsion stored at 45 ° C. for 3 months was measured using a digital electrical conductivity meter CM-50D (manufactured by Takemura Electric Co., Ltd.).

<Result>
As shown in Table 3, invention products 1-6 using a mixture of components (A) to (C) as essential components in the present invention product among the W / O / W type emulsions are 3 months at 45 ° C. Even after storage, a multiphase equivalent to that immediately after preparation was confirmed, and the coalescence of the inner aqueous phase and the outer aqueous phase was not confirmed. Also, the conductivity hardly changed between immediately after preparation and after storage at 45 ° C. for 3 months. However, comparative products 1 to 4 using a mixture of comparative components were confirmed to be multiphase in the same manner as the inventive product using a mixture of components (A) to (C) as essential components in the present invention immediately after preparation. Moreover, although the same degree of conductivity was shown, after storage for 3 months at 45 ° C., it was confirmed that no multiphase was observed in all the preparations and the conductivity was remarkably increased.
Therefore, the W / O / W type emulsion using the mixture of the components (A) to (C) as essential components in the product of the present invention has good temporal stability even if a large amount of electrolyte is blended in the inner aqueous phase. It was suggested that

  Next, practical examples of application of W / O / W emulsions, external preparations and cosmetics are given in Examples 2 to 9. However, it is not limited only to these examples. In addition, a compounding quantity is shown by the mass%.

W / O / W emulsion (A phase)
POE (10) hydrogenated castor oil 2.0%
Tocopherol acetate 0.3
Liquid paraffin 3.0
Tri (capryl / capric acid) glyceryl 5.0
Cyclomethicone 1.0
Preservative appropriate amount (phase B)
1,3-butylene glycol 2.0
Glycerin 2.0
PCA sodium 1.0
Apple tannin 0.1
Ascorbic acid 0.3
Purified water 20.0
(Phase C)
Preservative Appropriate amount It is an essential component in the product of the present invention. 1 4.0
Sodium hyaluronate 0.01
Purified water balance (preparation method)
The B phase component is added to the A phase component dissolved by heating and stirred with a homomixer to prepare a W / O emulsion in advance. After heating C phase to 80 degreeC and stirring with a homomixer, it cools with paddle stirring and cools to 35-30 degreeC. The W / O emulsion is added while stirring with a homomixer.

W / O / W emulsion (moisturizing cosmetic)
(Phase A)
POE (5) Phytosterol 2.0%
Tocopherol acetate 0.3
Olive Squalane 3.0
Macadamia nut oil 5.0
Dimethylpolysiloxane 1.0
Behenyl alcohol 0.3
Batyl alcohol 0.3
Stearic acid 0.2
Preservative appropriate amount (phase B)
Dipropylene glycol 2.0
Glycerin 2.0
THALITAN (hydrolyzed algin, magnesium sulfate,
Aqueous solution containing manganese sulfate) 5.0
Purified water 20.0
(Phase C)
Preservative Appropriate amount It is an essential component in the product of the present invention. 2 10.0
PCA potassium 1.0
Purified water balance (preparation method)
The B phase component is added to the A phase component dissolved by heating and stirred with a homomixer to prepare a W / O emulsion in advance. After heating C phase to 80 degreeC and stirring with a homomixer, it cools with paddle stirring and cools to 35-30 degreeC. The W / O emulsion is added while stirring with a homomixer.

W / O / W emulsion (whitening agent)
(Phase A)
Polyglycinoyl hexaglyceryl 1.8%
Diglyceryl monoisostearate 1.5
Hydrogenated soybean phospholipid 0.3
Cetyl ethylhexanoate 7.0
Methylphenylpolysiloxane 5.0
Preservative appropriate amount (phase B)
1,3-butylene glycol 2.0
Glycerin 2.0
L-ascorbyl magnesium phosphate 3.0
Sodium citrate 1.0
EDTA-4Na 0.05
Purified water 20.0
(Phase C)
Preservative Appropriate amount It is an essential component in the product of the present invention. 3 7.0
Purified water balance (preparation method)
The A phase component is heated and dissolved at 60 ° C. and then cooled to room temperature. The B phase component is added to the A phase component and stirred with a homomixer to prepare a W / O emulsion beforehand. After heating C phase to 80 degreeC and stirring with a homomixer, it cools with paddle stirring and cools to 35-30 degreeC. The W / O emulsion is added while stirring with a homomixer.

W / O / W emulsion (anti-aging cosmetic)
(Phase A)
POE (5) Phytosterol 1.0%
Polyglycinoyl hexaglyceryl 0.5
Hydrogenated retinol 0.3
Olive Squalane 3.0
Ascorbyl tetra-2-hexyldecanoate 3.0
Cyclomethicone 2.0
Preservative appropriate amount (phase B)
1,3-butylene glycol 2.0
Glycerin 2.0
Sodium hyaluronate 0.01
Ergothioneine 0.2
Purified water 20.0
(Phase C)
Preservative Appropriate amount It is an essential component in the product of the present invention. 3 4.0
PCA sodium 1.0
Purified water balance (preparation method)
The B phase component is added to the A phase component dissolved by heating and stirred with a homomixer to prepare a W / O emulsion in advance. After heating C phase to 80 degreeC and stirring with a homomixer, it cools with paddle stirring and cools to 35-30 degreeC. The W / O emulsion is added while stirring with a homomixer.

W / O / W emulsion (whitening cosmetic)
(Phase A)
Nikomurusu WO (Organic modified clay mineral, silicone emulsifier,
W / O emulsifier made of cyclic silicone, manufactured by Nikko Chemicals)
1.5%
Cetyl ethylhexanoate 1.0
Octyldodecanol 1.0
Dimethyl polysiloxane 3.0
Cyclomethicone 3.0
Preservative appropriate amount (Phase B)
Pentylene glycol 4.0
Glycerin 2.0
Sodium hyaluronate 0.01
Ascorbic acid disodium sulfate 3.0
Purified water 20.0
(Phase C)
Preservative Appropriate amount It is an essential component in the product of the present invention. 5 5.0
Pheohydran P (hydrolyzed algin, seawater,
Chlorella extract mixture) 3.0
Purified water balance (preparation method)
The B phase component is added to the A phase component and stirred with a homomixer to prepare a W / O emulsion beforehand. After heating C phase to 80 degreeC and stirring with a homomixer, it cools with paddle stirring and cools to 35-30 degreeC. The W / O emulsion is added while stirring with a homomixer.

W / O / W emulsion (whitening cosmetic)
(Phase A)
Nikomulus WO-NS (Organic modified clay mineral, W / O emulsifier made of polyglyceryl fatty acid ester, manufactured by Nikko Chemicals)
1.5%
Tocopherol acetate 0.2
Olive Squalane 4.0
Tri (capryl / capric acid) glyceryl 4.0
Cyclomethicone 2.0
Preservative appropriate amount (phase B)
Pentylene glycol 4.0
Glycerin 2.0
Xanthan gum 0.1
Sodium hyaluronate 0.01
Arbutin 3.0
Citric acid 0.1
Purified water 20.0
(Phase C)
Preservative appropriate amount 1,3-butylene glycol 3.0
A mixture No. (A) to (C) as essential components in the present product. 6 4.0
Glycine zinc 0.1
Purified water balance (preparation method)
The B phase component is added to the A phase component and stirred with a homomixer to prepare a W / O emulsion beforehand. After heating C phase to 80 degreeC and stirring with a homomixer, it cools with paddle stirring and cools to 35-30 degreeC. The W / O emulsion is added while stirring with a homomixer.

W / O / W emulsion (cream foundation)
(Phase A)
Polyglyceryl pentaisostearate 1.5%
Methylpolysiloxane / cetylmethylpolysiloxane / poly (oxyethylene / oxypropylene) methylpolysiloxane copolymer 0.2
Foundation powder base (silicone treatment)
8.0
Olive Squalane 1.0
Diisostearyl malate 3.0
Ethylhexyl methoxycinnamate 2.0
Cyclomethicone 5.0
Preservative appropriate amount (phase B)
Pentylene glycol 4.0
Glycerin 2.0
Sodium pyrrolidonecarboxylate 2.0
Purified water 20.0
(Phase C)
Preservative Appropriate amount It is an essential component in the product of the present invention. 1 4.0
Purified water balance (preparation method)
A phase component and B phase component are dissolved by heating. The B phase component is added to the A phase component and stirred with a homomixer to prepare a W / O emulsion beforehand. After heating C phase to 80 degreeC and stirring with a homomixer, it cools with paddle stirring and cools to 35-30 degreeC. The W / O emulsion is added while stirring with a homomixer.

W / O / W emulsion (anti-acne emulsion)
(Phase A)
Dextrin palmitate 0.5%
Liquid paraffin 10.0
Solid paraffin 1.0
Beeswax 1.0
Diglyceryl isostearate 1.5
Preservative appropriate amount (phase B)
Glycerin 5.0
Sodium glutamate 0.5
Phyco Anti-Acne (hydrolyzed algin,
Aqueous solution containing zinc sulfate) 5.0
Purified water 20.0
(Phase C)
Preservative Appropriate amount It is an essential component in the product of the present invention. 4 5.0
Purified water balance (preparation method)
A phase component and B phase component are dissolved by heating. The B phase component is added to the A phase component and stirred with a homomixer to prepare a W / O emulsion beforehand. After heating C phase to 80 degreeC and stirring with a homomixer, it cools with paddle stirring and cools to 35-30 degreeC. The W / O emulsion is added while stirring with a homomixer.

  In a W / O / W emulsion obtained by emulsifying and dispersing a W / O emulsion, (A) a straight chain and / or branched having 6 to 22 carbon atoms that may contain (A) an unsaturated bond in the outer aqueous phase. Even if a high concentration electrolyte is added to the inner aqueous phase by blending an alkylated polysaccharide having an alkyl group of (B), a phospholipid, and (C) an ionic surfactant as essential components, A stable W / O / W emulsion, an external preparation, and a cosmetic can be provided.

Claims (5)

W / O / W type emulsification obtained by emulsifying and / or dispersing a W / O type emulsion in an aqueous phase containing the following (A), (B) and (C) as essential components: object.
(A) an alkylated polysaccharide having a straight chain and / or branched alkyl group having 6 to 22 carbon atoms which may contain an unsaturated bond (B) phospholipid (C) ionic surfactant 2. The W / O / W type emulsion according to claim 1, wherein the W / O type emulsion contains an organically modified clay mineral as an essential component. The W / O / W emulsion according to claim 1 or 2, wherein the phospholipid is hydrogenated soybean phospholipid. The W / O / W type emulsion according to any one of claims 1 to 3, wherein an electrolyte and / or a water-soluble active ingredient is blended in any of the aqueous phases. A skin external preparation, a cosmetic, or a hair cosmetic, which is the W / O / W emulsion according to any one of claims 1 to 4.