JP2009148551A - Fever bag for infusion - Google Patents

Abstract

PROBLEM TO BE SOLVED: To cause a part of an infusion tube connecting between an infusion bag and an injection needle to meander, heat the infusion part of the meandering portion from the side, and warm the infusion, a temperature close to body temperature. Thus, a heating means for efficiently heating is provided without much time and effort.
SOLUTION: A heat generating composition that generates heat upon contact with oxygen in the air is a flat heat generating bag housed in a breathable bag, and generates heat around the heat generating bag in an air atmosphere at 20 ° C. The exothermic bag is prepared so that the time for maintaining the temperature between the maximum temperature of the exothermic composition and the temperature lower by 5 ° C. is 1 to 4 hours as exothermic characteristics in a state where there is no effect on And
[Selection] Figure 1

Description

  The present invention relates to an exothermic bag for infusion, and more particularly to an exothermic bag for efficiently warming an infusion to a temperature close to body temperature when infusion of the infusion to a patient or the like.

Conventionally, when an infusion is infused into a patient, a treatment for warming the infusion to a temperature close to body temperature has been performed in order to alleviate the patient's pain. The infusion solution is usually stored at a temperature of 10 ° C. or less, and it takes time and labor to warm the infusion solution filled in the infusion bag or the like, and it is necessary to maintain a preferable range of temperature during the infusion. In addition, once infused, the infusion solution has a disadvantage that it cannot be used again. Therefore, a part of the infusion tube connecting between the infusion bag and the injection needle is meandered, the infusion tube in the meandering part is heated from the side surface, and the infusion is heated efficiently as described in Patent Document 1. Tools have been developed.
Japanese Utility Model Publication No. 53-139798

As a heating means used for the infusion heating device as described above, for example, a heat storage material using heat released when the liquid becomes solid, or heat generated by a reaction between a metal such as iron and oxygen in the air. The exothermic composition used can be considered.
However, when a heat storage material is used, it is necessary to heat the heat storage material in advance, which takes time and effort, and for example, there are cases where it cannot be used because there is no electrical equipment outside the hospital. In addition, exothermic compositions that generate heat upon contact with oxygen in the air are widely used for disposable warmers, etc., but generally have a low initial temperature rise (rise) and are used to heat fluid. Therefore, there was a disadvantage that the calorific value per unit time was insufficient.

  Therefore, the problem to be solved by the present invention is to meander the part of the infusion tube that connects between the infusion bag and the injection needle, warm the infusion part of the meandering portion from the side, and warm the infusion. In the heating means of an infusion heating tool, it is to provide a heating means for efficiently heating an infusion without spending time and effort until it reaches a temperature close to body temperature.

  As a result of intensive studies to solve these problems, the inventors of the present invention have developed a flat exothermic bag in which a heat generating composition that generates heat upon contact with oxygen in the air is contained in a breathable bag. By using a means such as limiting the air permeability (water vapor permeability) of the packaging material, the heat generation peak time is concentrated in a shorter time than a normal heat generation bag used as a disposable body warmer, It was found that the initial temperature rise (rise) was fast and the calorific value per unit time was sufficiently large, and reached the exothermic bag for infusion of the present invention.

  That is, the present invention is a flat heating bag in which a heating composition that generates heat upon contact with oxygen in the air is housed in a breathable bag, and is placed around the heating bag in an air atmosphere at 20 ° C. As a heat generation characteristic in a state where there is no influence on the heat generation, the time for maintaining the temperature between the maximum temperature of the heat generation composition and a temperature lower by 5 ° C. is adjusted to be 1 to 4 hours. Is a heat-generating bag for infusion.

  The exothermic bag for infusion of the present invention concentrates the exothermic effect of the exothermic composition in a short time, so that the initial temperature rise (rise) is fast and the calorific value per unit time is sufficiently large. The temperature can be efficiently heated. Furthermore, by providing a means for holding the infusion tube and a means for adhering to the infusion bag or the infusion tube holder in the packaging material of the heating bag, the adhesion to these can be improved, and the infusion can be heated more efficiently. It is possible.

The exothermic bag for infusion of the present invention is applied to an exothermic bag for heating an infusion using a exothermic composition that generates heat upon contact with oxygen in the air.
Hereinafter, although the exothermic bag for infusion of this invention is demonstrated in detail based on FIGS. 1-8, this invention is not limited by these. FIG. 1 is a cross-sectional view showing an example of an infusion heating bag according to the present invention. FIG. 2 is a perspective view (partially cutaway perspective view) showing an example of a heat generating bag for infusion of the present invention. FIG. 3 is a cross-sectional view showing an example of the exothermic bag for infusion of the present invention other than FIG. FIG. 4 is a configuration diagram showing an arrangement example of the pressure-sensitive adhesive portion provided on the surface of the packaging material in the infusion bag for infusion of the present invention. FIG. 5 is a perspective view showing an example of a means for holding an infusion tube provided in a packaging material in the exothermic bag for infusion of the present invention. FIG. 6 is a perspective view showing an example of means for adhering to an infusion bag or an infusion tube holder provided in a packaging material in the exothermic bag for infusion of the present invention. FIG. 7 is a configuration diagram showing an example of an infusion tube holder. FIG. 8 is a graph showing an example of the heat generation characteristic (solid line) of the heat generation bag for infusion of the present invention.

  As shown in FIGS. 1 and 2, the exothermic bag for infusion of the present invention comprises a exothermic composition 1 that generates heat upon contact with oxygen in the air, and is contained in a bag having a breathable packaging material 2. As a heat generation characteristic in a flat exothermic bag, in a state where there is no influence on the heat generation around the heat generation bag in an air atmosphere of 20 ° C., it is between the maximum temperature of the exothermic composition and a temperature lower by 5 ° C. The heating bag is prepared so that the time for maintaining the temperature is 1 to 4 hours, preferably 1.2 to 3.5 hours, and more preferably 1.5 to 3 hours. As a configuration of the flat heating bag, both sides can be made breathable, or one side can be made breathable and the other side can be made non-breathable.

In the present invention, for example, the exothermic composition comes into contact with air and the temperature rises, reaches a temperature 5 ° C. lower than the maximum temperature after time t ₁ , then reaches the maximum temperature after time t ₂ , and further after time t ₃ . When the temperature is 5 ° C lower than the maximum temperature again, the time for maintaining the temperature between the maximum temperature of the exothermic composition and the temperature 5 ° C lower than that is (t ₃ -t ₁ ), In the exothermic bag for infusion, it is prepared to be 1 to 4 hours. Note that the above time is a room temperature (20 ° C.), normal pressure, no air (air) environment, no heat generation hindrance or influence around the heat generation bag, for example, a state where the heat generation bag is hung from the ceiling Shall be measured in

In order to easily exhibit such heat generation characteristics, the breathable packaging material in the present invention has a total water vapor transmission rate of 500 to 1200 g / m ² according to the JISK7129A method on one side and the other side. It is selected to be 24 hr, preferably 600 to 1000 g / m ² · 24 hr. For example, when a non-breathable packaging material is used on one side, the water vapor permeability of the other one side is 500 to 1200 g / m ² · 24 hr, and the same packaging material is used on both sides. The water vapor permeability of the packaging material is 250 to 600 g / m ² · 24 hr.

  In the exothermic bag for infusion of the present invention, a flat infusion tube, a flat infusion tube holder, or a flat infusion bag is efficiently used from both sides by using one exothermic bag. In order to warm, as shown in FIG. 3, the exothermic composition storage part can be divided into two parts. When such a heating bag is used, the infusion solution can be obtained by folding the bonding portion 4 formed in the central portion of the heating bag into two folds and sandwiching the infusion tube, the infusion tube holder, or the infusion bag. Heating is performed.

  As a raw material of the flat bag packaging material used in the present invention, usually a laminated sheet containing a plastic film is used. As these laminated sheets, for example, (1) heat-fusibility Component layer / plastic film, (2) (mixed film of heat fusible component and plastic component) / plastic film, (3) heat fusible component layer / plastic film / heat fusible component layer / nonwoven fabric, (4 ) (Mixed film of heat-fusible component and plastic component) / bonded sheet made of non-woven fabric. In addition, as a plastic film, a polyethylene film, a polypropylene film, a polyester film, a nylon film, etc. can be illustrated.

  As the air-permeable plastic film used in the present invention, it is preferable to use a plastic film provided with microporous air holes. Such a microporous plastic film is a film having fine pores having a pore diameter of 0.01 μm or more and 10 μm or less. For example, after calcium carbonate is dispersed in molten plastic (polyethylene, polypropylene, etc.), the film is formed into a film shape. It is obtained by extruding and stretching. When a microporous plastic film is used, it is easy to control the air permeability (water vapor permeability), and when the heat generating bag is used, the heat generating composition reaches the maximum temperature as shown in the graph (solid line) of FIG. Since the subsequent temperature drop is relatively fast, it is easy to control the exothermic peak time to concentrate in a short time.

In the present invention, a plastic film having needle holes (usually having a diameter of 50 μm or more) can be used. However, it is more difficult to control the air permeability (water vapor permeability) than the microporous plastic film, and the heat generation composition Since the temperature drop after the object reaches the maximum temperature is gradual, it is difficult to concentrate the exothermic peak time in a short time.
Furthermore, when a microporous plastic film is used, there is an advantage that the exothermic composition is less likely to be biased when the infusion solution is heated, compared to the case where a plastic film having a needle hole is used.

  The size of the vent of the breathable plastic film used in the present invention is preferably about 0.01 to 30 μm, but the position of the vent is not particularly limited. It can be suitably formed on the entire surface, central portion, peripheral portion, or part of the bonded sheet. However, it is preferable that air holes having the same size and shape are formed at equal intervals on the entire surface of the bonded sheet. In addition, when providing the vent hole with which arrangement | positioning, a magnitude | size, etc. are biased, it is preferable to set so that the water vapor transmission rate by the JISK7129A method may become the above-mentioned range as the whole packaging material.

  In the exothermic bag for infusion of the present invention, when a packaging material having a water vapor permeability in the range as described above is used, as an exothermic characteristic when used for warming infusion under an atmosphere at room temperature (20 ° C.), infusion Within 3 minutes (time after contacting the exothermic composition with oxygen in the air), and the time for maintaining the infusion solution at a temperature around 1 body temperature. It becomes easy to set it to ~ 4 hours. If the water vapor transmission rate is set to be smaller than the above range, the initial temperature rise (rise) may be delayed or may not reach a temperature around the body temperature, and the water vapor transmission rate may be larger than the above range. When set, the initial temperature rise (rise) is accelerated, but the temperature holding time around the body temperature is shortened.

  In the exothermic bag for infusion of the present invention, the flat bag is preferably provided with means for holding the infusion tube, means for adhering to the infusion bag, or means for adhering to the infusion tube holder. These are provided in one of the packaging materials when a breathable packaging material having the same water vapor permeability is used on both sides. Moreover, when the packaging material from which water vapor permeability differs mutually is used for each surface, it is preferable to provide in one side with the smaller water vapor permeability.

  As the means for holding the infusion tube, the means for adhering to the infusion bag, or the means for adhering to the infusion tube holder, an adhesive part 5 provided on the surface of the packaging material can be exemplified as shown in FIG. . There is no particular limitation on the arrangement position, size, etc. of the pressure-sensitive adhesive part 5, for example, the pressure-sensitive adhesive part having the same size and shape on the entire surface, central part, peripheral part, or part of the packaging material, Alternatively, a plurality of types of pressure-sensitive adhesive parts having different sizes and shapes can be formed, but it is preferable to form pressure-sensitive adhesive parts having the same size and shape on the entire surface of the packaging material at equal intervals.

  The ratio of the area with respect to the whole packaging material of the single side | surface of an adhesive part is 2-40% normally, Preferably it is 5-20%. When the ratio of the area with respect to the whole one surface of an adhesive part is less than 2%, there exists a possibility that holding | maintenance of an infusion tube, adhesion | attachment to an infusion bag, or adhesion | attachment to an infusion tube holder may become impossible. Moreover, although an adhesive part can also be provided in the whole single side | surface, it is preferable that the ratio of the area with respect to the whole single side | surface of an adhesive part is 40% or less at the point from which a favorable initial temperature rise (rise) is obtained.

  As the pressure-sensitive adhesive part, a pressure-sensitive adhesive layer can be directly provided on the packaging material, but a tape or sheet layer (double-sided tape) provided with a pressure-sensitive adhesive layer on both sides can also be provided. By adopting such a structure composed of three layers of pressure-sensitive adhesive layer / tape or sheet layer / pressure-sensitive adhesive layer, the thickness of the pressure-sensitive adhesive portion is increased, and a gap with an infusion bag, an infusion tube holder, etc. is generated and aeration is performed. Can be improved. The adhesive is covered with release paper or the like until it is used.

  As other infusion tube holding means, a fixing member 7 of the infusion tube 6 can be exemplified as shown in FIG. When the fixing member 7 is provided, it is usually provided on the surface of the bonding portion 4. The fixing member 7 can be manufactured, for example, by attaching an elongated tape to the surface of the packaging material so that a space for the infusion tube to pass through is formed. Further, a penetrating part (circular shape with a diameter of about 0.2 to 1 cm or a size corresponding to this) for passing the infusion tube through the peripheral part (bonding part) of the air-permeable packaging material, A cutout portion (a semicircular shape having a diameter of about 0.2 to 1 cm or a shape corresponding to this) can be provided to fix the position. Moreover, as an adhesion means to other infusion bags or an adhesion means to the infusion tube holder, as shown in FIG. 6, a band 8 having an adhesive portion 5 can be exemplified. These fixing member 7 and band 8 can also be used in combination with the pressure-sensitive adhesive part 5 provided on the surface of the packaging material.

In the exothermic bag for infusion of the present invention, a mixture of an oxidizable metal, activated carbon, an inorganic electrolyte, water, and a polymer water retention agent is used as the exothermic composition that generates heat upon contact with oxygen in the air. .
Examples of the oxidizable metal powder include iron powder and aluminum powder, but iron powder is usually used, and reduced iron powder, atomized iron powder, electrolytic iron powder, and the like are used. Activated carbon is used as a water retention agent in addition to a reaction aid, and usually coconut shell charcoal, wood dust charcoal, peat charcoal and the like are used. As the inorganic electrolyte, alkali metal, alkaline earth metal, heavy metal chloride, alkali metal sulfate and the like are preferable, for example, sodium chloride, potassium chloride, calcium chloride, magnesium chloride, ferric chloride, sodium sulfate and the like. Is used. The ratios of these normal components are 20-80 wt% for oxidizable metals, 1-20 wt% for activated carbon, 1-20 wt% for inorganic electrolyte, 5-50 wt% for water, and 1-20 wt% for water retention agent. It is.

The exothermic bag for infusion of the present invention is composed of, for example, two breathable packaging materials or a breathable packaging material and a non-breathable packaging material so that the heat-sealing surfaces are inside each other, The periphery is heat-fused and formed into a bag shape, and filled with the above-described heat-generating composition to form a heat-generating bag as shown in FIGS. Moreover, the size of the exothermic bag for infusion of the present invention is usually about the same size as a business card, and is about Japanese Industrial Standard A row No. 3. The shape is usually rectangular, but may be circular, elliptical, polygonal, or the like.
The exothermic bag for infusion of the present invention is sealed in a non-breathable flat bag in order to shut off from outside air and prevent water from evaporating and diffusing outside during the period until it is used. Is done. In use, the exothermic composition in the exothermic bag comes into contact with oxygen in the air to generate heat by taking it out from the non-breathable flat bag.

  The heating bag for infusion of the present invention, when directly heating the infusion tube, for example, as shown in FIG. 5, the infusion tube is fixed in a serpentine shape on the surface of the packaging material of the heating bag, or further the serpentine shape Another one exothermic bag is bonded from the side so as to sandwich the infusion tube. Moreover, when heating an infusion bag or an infusion tube holder, it adhere | attaches on these one side surfaces or both side surfaces. In the present invention, as shown in FIG. 7, the infusion tube holder has an infusion tube that holds the infusion tube in a serpentine shape, and has two flow paths for circulating the infusion in a serpentine shape. In addition to those having the function of coupling the tubes, those that hold the infusion tube in a spiral shape or those that circulate the infusion solution in a spiral shape are included.

EXAMPLES Next, although an Example demonstrates this invention concretely, this invention is not limited by these.
[Example 1]

(Production of fever bag)
As a breathable packaging material on one side, a packaging material composed of a microporous polyethylene film having a thickness of 90 μm and a nylon nonwoven fabric having a thickness of 20 μm was used. This breathable packaging material had a water vapor permeability of 600 g / m ² · 24 hr according to the JIS K7129A method.
Moreover, the packaging material which provided the adhesive part uniformly disperse | distributed as shown to FIG. 4 (1) was used for the nylon nonwoven fabric side of the said breathable packaging material as another one-sided breathable packaging material. Release paper is temporarily superimposed on the adhesive part. This packaging material had reduced air permeability due to the pressure-sensitive adhesive part, and had a water vapor permeability of 300 g / m ² · 24 hr according to the JISK7129A method.

These packaging materials are cut into 100 mm × 150 mm, and further, a tape-like polyethylene infusion tube is formed on the nylon nonwoven fabric side periphery of the low-breathability packaging material so as to have a form as shown in FIG. A fixing member was attached and provided.
Also, in a nitrogen gas atmosphere, an exothermic composition is prepared by mixing so that the iron powder is 62 wt%, the activated carbon is 8 wt%, the salt (inorganic electrolyte) is 2 wt%, the water is 20 wt%, and the water retention agent is 8 wt%. did. The two breathable packaging materials described above are overlapped so that the heat-sealing surfaces are inside, and the periphery is heat-fused to form a bag and filled with 45 g of exothermic composition, as shown in FIG. A fever bag like this was made. Thereafter, the heating bag was sealed in a 120 mm × 180 mm non-breathable flat bag.

(Investigation of heat generation characteristics of heat generation bag)
Ten exothermic bags as described above were produced and left in a room at 20 ° C. for one day and night. Next, the heat generation characteristics of these 10 heat generation bags were measured in a state where the heat generation bags were taken out from the non-breathable flat bag and suspended from the ceiling at 20 ° C. As a result, the exothermic compositions of all the exothermic bags reached 30 ° C. within 4 minutes. Regarding the time for maintaining the temperature between the maximum temperature of the exothermic composition and the temperature 5 ° C. lower than that, the average of 10 bags is 2.8 hours, the shortest is 2.5 hours, and the longest is 3.0 hours. there were. The heat generation characteristics of these heat generation bags were as shown in the graph (solid line) in FIG.

(Infusion warming survey)
In order to hold the infusion tube with the heating bag in a meandering manner and heat it, a heating bag for facing was manufactured in the same manner as above except that the fixing member for the infusion tube was not provided. Sealed in a flat bag.
A heating bag provided with an infusion tube fixing member and a facing heating bag not provided with an infusion tube fixing member were allowed to stand overnight in a room at 20 ° C. Next, these heating bags are taken out from the non-breathable flat bag in a room at 20 ° C., and the infusion tube is passed through the fixing member of the heating bag provided with the fixing member of the infusion tube so as to form a meandering shape. Furthermore, the heat-generating bag for facing was fixed by overlapping the adhesive part side so that the infusion tube was sandwiched. Five minutes after taking out the heat generating bag from the non-breathable flat bag, an infusion solution at 20 ° C. is circulated from the infusion bag to the infusion tube at a flow rate of 3 cc / min, and passes through the infusion tube sandwiched between the exothermic bags. The temperature of the infusion solution was measured about every 5 minutes. As a result, an infusion solution at 30 ° C. or higher was obtained over 2 hours.
[Example 2]

(Production of fever bag)
As a breathable packaging material on one side, a packaging material made of a microporous polyethylene film having a thickness of 80 μm and a nylon nonwoven fabric having a thickness of 20 μm was used. This breathable packaging material had a water vapor permeability of 900 g / m ² · 24 hr according to the JISK7129A method.
Further, as the non-breathable packaging material, a bonded packaging material made of a commercially available polyethylene film and nylon film was used, and a uniformly dispersed adhesive part as shown in FIG. 4 (1) was provided on the nylon film side.
A heat-generating bag was produced in the same manner as in Example 1 except that these breathable packaging material and non-breathable packaging material were used and the fixing member for the infusion tube was not provided. Thereafter, the heating bag was sealed in a 120 mm × 180 mm non-breathable flat bag.

(Investigation of heat generation characteristics of heat generation bag)
Ten exothermic bags as described above were produced and left in a room at 20 ° C. for one day and night. Next, the heat generation characteristics of these 10 heat generation bags were measured in a state where the heat generation bags were taken out from the non-breathable flat bag and suspended from the ceiling at 20 ° C. As a result, the exothermic compositions of all the exothermic bags reached 30 ° C. within 4 minutes. In addition, the time for maintaining the temperature between the maximum temperature of the exothermic composition and the temperature 5 ° C lower than that is 2.7 hours on the average of 10 bags, 2.5 hours at the shortest, and 2.9 hours at the longest. there were.

(Infusion warming survey)
Two exothermic bags left in a room at 20 ° C. for one day are taken out from the non-breathable flat bag, and an infusion warming device (100 mm × 100 mm) having a flow path through which the infusion is circulated as shown in FIG. 150 mm) was attached to each side.
5 minutes after taking out the fever bag from the non-breathable flat bag, the infusion solution passed through the infusion warming device through the infusion bag at a flow rate of 20 ° C. at a flow rate of 3 cc / min. Was measured approximately every 5 minutes. As a result, an infusion solution at 30 ° C. or higher was obtained over 2.2 hours.

[Comparative Example 1]
(Investigation of heat generation characteristics of commercially available portable body warmers)
Ten commercially available bags of portable hand warmers were left in a room at 20 ° C. for a whole day and night. The exothermic composition of this portable body warmer has substantially the same composition, filling amount and the like as in Example 1 and Example 2. Next, with respect to these portable warmers, the heat generation characteristics were measured in a state where the heat generation bag was taken out from the non-breathable flat bag and suspended from the ceiling at 20 ° C. As a result, the exothermic composition of all the exothermic bags did not reach 30 ° C. within 5 minutes. In addition, the time for maintaining the temperature between the maximum temperature of the exothermic composition and the temperature 5 ° C lower than that was 9.5 hours on average for 10 bags, 7.8 hours for the shortest, and 10 hours or more for the longest. It was. The heat generation characteristics of these heat generation bags were as shown in the graph (dotted line) in FIG.

(Infusion warming survey)
A heat-generating bag of two commercially available portable body warmers that are left in a room at 20 ° C. for one day is taken out of the non-breathable flat bag and has a flow path for circulating the infusion as shown in FIG. One bag was adhered to each side of the infusion warming device (100 mm × 150 mm).
5 minutes after taking out the fever bag from the non-breathable flat bag, the infusion solution passed through the infusion warming device through the infusion bag at a flow rate of 20 ° C. at a flow rate of 3 cc / min. Was measured approximately every 5 minutes. As a result, the maximum temperature of the infusion was about 27 ° C.

  As described above, the exothermic bag for infusion of the embodiment of the present invention has a fast initial temperature rise (rise), a sufficiently large calorific value per unit time, and can efficiently warm the infusion to a predetermined temperature. Became clear.

Sectional drawing which shows the example of the exothermic bag for infusion of this invention The perspective view which shows an example of the exothermic bag for infusion of this invention (partially cutaway perspective view) Sectional drawing which shows an example of the exothermic bag for infusions of this invention other than FIG. In the exothermic bag for infusion of this invention, the block diagram which shows the example of arrangement | positioning of the adhesive part provided in the surface of a packaging material The perspective view which shows an example of the holding means of the infusion tube provided in a packaging material in the exothermic bag for infusion of this invention The perspective view which shows an example of the adhesion | attachment means to the infusion bag or infusion tube holder provided in a packaging material in the exothermic bag for infusion of this invention Configuration diagram showing an example of an infusion tube holder The graph which shows an example of the exothermic characteristic of the exothermic bag for infusion of this invention

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Exothermic composition 2 Breathable packaging material 3 Non-breathable packaging material 4 Bonding part 5 Adhesive part 6 Infusion tube 7 Fixing member 8 Band 9 Infusion tube holder

Claims (10)

  A heat generating composition that generates heat upon contact with oxygen in the air is a flat heat generating bag housed in a breathable bag, and affects the heat generation around the heat generating bag in an air atmosphere at 20 ° C. As an exothermic property in a state where there is nothing, the infusion is characterized in that the time for maintaining the temperature between the maximum temperature of the exothermic composition and a temperature lower by 5 ° C. is 1 to 4 hours. Fever bag for use. ^2. The infusion solution according to claim 1, comprising a packaging material having a total water vapor permeability of 500 to 1200 g / m ² · 24 hr according to JISK7129A method as one of the breathable packaging materials and the other one surface. Fever bag.   The exothermic bag for infusion according to claim 2, wherein the air-permeable packaging material is a packaging material in which micropores having a pore diameter of 0.01 to 10 µm are provided on a plastic film.   The exothermic bag for infusion according to claim 1, wherein the storage portion for the exothermic composition is divided into two.   The exothermic bag for infusion according to claim 1, wherein the packaging material is provided with means for holding the infusion tube.   The exothermic bag for infusion according to claim 1, wherein the packaging material is provided with means for adhering to the infusion bag or the infusion tube holder.   The exothermic bag for infusion of Claim 1 which has the adhesive part disperse | distributed to two or more on the surface of the packaging material of one side.   The exothermic bag for infusion according to claim 7, wherein the ratio of the area of one side of the adhesive part to the whole packaging material is 2 to 40%.   The exothermic bag for infusion according to claim 7, wherein the pressure-sensitive adhesive part comprises a tape or a sheet having a pressure-sensitive adhesive layer on both sides.   The infusion exothermic bag according to claim 1, wherein the flat exothermic bag is further sealed in a non-breathable flat type bag.

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